Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P00750 (
PLA
)
16,800
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PLA
16800
plasminogen
2661
urokinase-type plasminogen activator
2473
plasminogen activator inhibitor-1
1408
tissue plasminogen activator
1352
fibrinogen
1206
plasminogen activator inhibitor
1198
Sep
1148
thrombin
948
PEG
667
Plasminogen
566
Mol
538
collagen
468
u-PA
328
SDS
306
tPA
299
insulin
294
serine protease
289
antithrombin III
286
von Willebrand factor
283
PAI
269
fibronectin
263
prothrombin
251
thromboplastin
214
NMR
210
PCL
208
tissue factor
206
PAI-2
205
Plasmin
201
antithrombin
195
protein C
190
cytokine
185
Poly
181
inhibitor-1
173
matrix metalloproteinase
172
glycoprotein
169
thrombomodulin
159
urokinase plasminogen activator
158
uPAR
157
collagenase
155
bradykinin
143
epidermal growth factor
142
cyclooxygenase
138
tumor necrosis factor
137
phospholipase
134
ACS
132
fused
122
lipopolysaccharide
119
serum albumin
117
ADP
115
albumin
110
PGA
109
Phospholipase A2
109
polypeptide
107
C-reactive protein
107
factor VIII
106
vitronectin
106
vascular endothelial growth factor
105
factor VII
105
TNF
101
metalloproteinase
100
vascular endothelium
100
MMP-9
99
kallikrein
97
MMP-2
97
protein S
95
phospholipase A2
93
osteogenic
91
alpha 2-plasmin inhibitor
87
alkaline phosphatase
86
PBS
83
AMP
83
IL-6
79
casein
79
HDL
78
DSC
78
p38
76
COX-2
74
TPA
73
ATP
73
more...
Disease
stroke
1085
cancer
1024
tumor
988
acute myocardial infarction
641
myocardial infarction
493
SDS
306
atherosclerosis
304
ischemia
257
melanoma
230
breast cancer
222
diabetes
220
pulmonary embolism
215
PCL
208
hypertension
206
carcinoma
200
SEM
188
cardiovascular disease
166
deep vein thrombosis
143
tumor growth
139
disseminated intravascular coagulation
127
metastases
122
hepatocellular carcinoma
119
coronary artery disease
113
plaque
113
cerebral ischemia
111
PGA
110
MCF
104
sepsis
102
obesity
97
sepsis
92
coronary heart disease
91
coronary thrombosis
88
Yersinia
77
Alzheimer's disease
76
myocardial ischemia
72
Thrombus
68
adenocarcinoma
67
cerebral infarction
65
leukemia
65
heart failure
65
vascular disease
65
coagulopathy
64
systemic lupus erythematosus
64
rheumatoid arthritis
63
glioma
63
unstable angina
60
TEM
60
fibrosarcoma
60
arthritis
59
TEM
59
thrombocytopenia
57
squamous cell carcinoma
56
cold
55
lung cancer
55
tumor progression
55
IVA
54
cirrhosis
52
prostate cancer
51
LAP
51
depression
50
type 2 diabetes
49
carcinogenesis
48
Rous sarcoma
45
colon cancer
44
pertussis
43
plague
42
lupus
42
neurological disease
42
uterus
42
ovarian cancer
42
renal disease
41
multiple sclerosis
39
neuroblastoma
39
pneumonia
38
glioblastoma
38
pulmonary hypertension
38
preeclampsia
37
multiple myeloma
37
lung carcinoma
37
hyperlipidemia
37
more...
Symptom
pain
97
chest pain
73
angina
64
anesthesia
40
functional recovery
33
fatigue
32
exhaustion
31
collapse
30
respiratory distress
26
seizures
26
overweight
25
hypothermia
20
dyspnea
19
discomfort
13
flushing
12
hemiplegia
12
discomfort
12
shortness of breath
11
weakness
11
spasm
10
headache
9
thinning
9
acidity
9
nausea
9
abdominal pain
8
starvation
8
tremor
8
syncope
7
tachypnea
7
dysarthria
7
cough
6
vertigo
6
stigma
6
diarrhea
6
analgesia
6
numbness
6
ataxia
6
sleepiness
5
agitation
5
pelvic pain
5
consciousness disturbance
5
hyperoxia
5
vomiting
5
disturbed balance
4
hepatomegaly
4
acute stress
4
dizziness
4
livedo
4
regurgitation
4
cyanosis
4
skin damage
4
arm pain
3
myalgia
3
exertional dyspnea
3
hemoptysis
3
paresis
3
neurological disability
3
Fluctuation
3
back pain
3
cachexia
2
skin irritation
2
sneezing
2
low back pain
2
leg pain
2
ENT
2
abdominal discomfort
2
paraparesis
2
hypercapnia
2
splenomegaly
2
nasal discharge
2
productive cough
2
acute abdominal pain
2
tinnitus
2
erythema
2
incoordination
2
acute pain
2
catatonia
1
rigors
1
neck pain
1
pedal edema
1
more...
Drug
lysine
365
uPA
364
Alteplase
173
Alteplase
156
Alteplase
151
Cardiovasc
147
Urokinase
134
Streptokinase
102
Dermatol
75
DDAVP
60
DDAVP
59
Gel
51
Asn
47
MAP
30
Tenecteplase
30
vitamin E
29
DFP
29
TAT
25
ROS
25
CSF
24
Taxol
23
nitroglycerin
23
caffeine
21
CaCl2
19
Aprotinin
19
CaCl2
19
CaCl2
19
Dial
18
ascorbate
18
Nephron
18
Retinoic acid
17
ZnO
17
THF
17
Docetaxel
16
lactose
16
CTA
15
IFN-gamma
15
EE2
15
Activase
15
Argatroban
14
Nephron
14
Indomethacin
14
IL-2
12
EPA
12
Vitamin E
11
Angiotensin II
11
ABC
11
PPA
11
Ancrod
10
Monit
10
ADR
10
ACT
10
citric acid
10
Cremophor EL
9
Taxotere
9
Dalteparin
9
Fragment
9
Captopril
9
G418
9
Lactic Acid
9
Biopolymers
8
FeCl3
8
Gelatin
8
PTH
8
Forskolin
8
ROC
7
DNase I
7
Leaf
7
Desmoteplase
7
Antithrombin III
7
Simvastatin
7
Darapladib
7
Albumin
7
Tacrolimus
7
ALA
7
GEO
6
TiO2
6
Lanoteplase
6
Fraction
6
ENT
6
more...
Enzyme
tissue plasminogen activator
5663
urokinase-type plasminogen activator
2635
plasmin
1891
phospholipase A2
1375
thrombin
922
ERK
308
thromboplastin
266
APC
248
trypsin
246
collagenase
193
mitogen-activated protein kinase
192
protein kinase C
187
ACS
132
kallikrein
124
elastase
114
protein kinase
113
alkaline phosphatase
86
peroxidase
82
phospholipase C
80
MMP-3
61
lipoxygenase
61
creatine kinase
59
renin
57
ACE
57
focal adhesion kinase
55
chymotrypsin
50
superoxide dismutase
49
lipase
49
lysozyme
47
thrombin-activatable fibrinolysis inhibitor
46
lactate dehydrogenase
42
phospholipase D
39
phosphodiesterase
38
matrix metalloproteinase 2
37
cathepsin B
36
cathepsin D
35
MEK
34
cathepsin G
33
catalase
33
adenylate cyclase
33
caspase-3
32
reverse transcriptase
32
NADPH oxidase
31
MMP
29
matrix metalloproteinase 9
28
beta-glucuronidase
26
ATPase
26
luciferase
26
NO synthase
26
NADPH oxidase
26
hyaluronidase
25
transglutaminase
25
TAT
25
Pla
25
interstitial collagenase
24
acid phosphatase
24
neutrophil elastase
24
hyaluronidase
22
carboxypeptidase B
22
lipoprotein lipase
22
proteinase K
22
ancrod
21
enolase
19
neuropathy target esterase
19
tryptase
18
ornithine decarboxylase
18
deaminase
18
beta-galactosidase
18
Hageman factor
16
tissue kallikrein
15
AMPK
15
DNase
14
P-glycoprotein
14
alanine aminotransferase
14
glutathione S-transferase
13
heparinase
13
glutathione peroxidase
13
proteasome
13
subtilisin
12
glyceraldehyde-3-phosphate dehydrogenase
12
more...
Compound
PLA
6020
Dec
1239
PEG
865
PEG
790
Clin
658
water
652
calcium
557
lysine
532
DNA
528
serine
413
sodium
412
Cardiol
361
arginine
355
oxygen
351
acetate
338
SDS
327
sulfate
287
phosphate
276
glucose
269
Lactic acid
196
Plasmin
194
ACS
188
prostacyclin
162
Fibrin
154
cAMP
148
nitric oxide
141
ADP
137
retinoic acid
134
ACS
132
Asp
124
alanine
122
tyrosine
120
hydrogen
118
Fibrinogen
118
Gly
118
PGA
116
ADP
115
His
115
ADP
115
cysteine
114
Thrombin
112
PGE
109
bromide
107
leucine
104
salt
104
MTT
102
TNF
101
Heparin
98
zinc
93
galactose
91
Phe
90
AMP
85
TEM
85
iron
83
ethanol
83
methionine
81
EDTA
78
copper
77
CO2
75
ATP
74
ASA
72
TOF
71
EDTA
71
nitrogen
70
FDP
68
MDA
67
ammonium
63
NH2
62
Triton X-100
62
urea
62
vinyl
57
PVA
54
carbonate
54
glutamate
53
glutamic acid
51
dichloromethane
51
glycerol
50
Cereb
50
creatinine
50
PAR
49
more...