Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P00750 (
PLA
)
16,800
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PLA
16800
plasminogen
2661
urokinase-type plasminogen activator
2473
plasminogen activator inhibitor-1
1408
tissue plasminogen activator
1352
fibrinogen
1206
plasminogen activator inhibitor
1198
Sep
1148
thrombin
948
PEG
667
Plasminogen
566
Mol
538
collagen
468
u-PA
328
SDS
306
tPA
299
insulin
294
serine protease
289
antithrombin III
286
von Willebrand factor
283
PAI
269
fibronectin
263
prothrombin
251
thromboplastin
214
NMR
210
PCL
208
tissue factor
206
PAI-2
205
Plasmin
201
antithrombin
195
protein C
190
cytokine
185
Poly
181
inhibitor-1
173
matrix metalloproteinase
172
glycoprotein
169
thrombomodulin
159
urokinase plasminogen activator
158
uPAR
157
collagenase
155
bradykinin
143
epidermal growth factor
142
cyclooxygenase
138
tumor necrosis factor
137
phospholipase
134
ACS
132
fused
122
lipopolysaccharide
119
serum albumin
117
ADP
115
albumin
110
Phospholipase A2
109
PGA
109
C-reactive protein
107
polypeptide
107
vitronectin
106
factor VIII
106
factor VII
105
vascular endothelial growth factor
105
TNF
101
vascular endothelium
100
metalloproteinase
100
MMP-9
99
kallikrein
97
MMP-2
97
protein S
95
phospholipase A2
93
osteogenic
91
alpha 2-plasmin inhibitor
87
alkaline phosphatase
86
PBS
83
AMP
83
casein
79
IL-6
79
HDL
78
DSC
78
p38
76
COX-2
74
ATP
73
TPA
73
MAPK
72
FSH
72
Lp(a)
71
GPIIb
71
TOF
71
hemoglobin
68
FDP
68
ERK1
67
lipoprotein receptor-related protein
67
VIII
66
interleukin-6
65
factor Xa
65
factor XII
64
angiotensin II
64
TGF-beta
64
PLA2
62
IL-1
62
vWF
61
LPS
60
MRI
59
lipoxygenase
59
TEM
59
EPA
58
thrombin-activatable fibrinolysis inhibitor
58
protease inhibitor
58
renin
57
PLC
57
esterase
57
Pol
56
PEO
56
IVA
54
membrane-bound
53
TNF-alpha
52
creatine kinase
52
peroxidase
52
PVA
50
PKC
50
nitric oxide synthase
50
PAR
49
MMP-1
49
serine protease inhibitor
48
lysozyme
47
interferon
46
lipase
46
Tissue plasminogen activator
46
matrix metalloproteinase 2
46
beta-thromboglobulin
45
transforming growth factor-beta
45
VEGF
45
hepatocyte growth factor
45
ERK
44
tissue factor pathway inhibitor
44
nexin
44
tyrosine kinase
44
trypsin inhibitor
43
She
43
plasminogen activator inhibitor 2
43
vasopressin
43
caspase-3
42
endoplasmic reticulum
42
MMP-3
42
thrombin inhibitor
41
chymotrypsin
41
estrogen receptor
41
epidermal growth factor receptor
41
PHB
40
type I collagen
40
Pseudomonas
40
superoxide dismutase
39
phospholipase D
39
tumor necrosis factor alpha
39
Ang II
39
lectin
39
transferrin
39
PCI
38
dimeric
38
5-lipoxygenase
37
phosphodiesterase
37
Factor VIII
36
PGF
36
more...
Disease
stroke
1085
cancer
1024
tumor
988
acute myocardial infarction
641
myocardial infarction
493
SDS
306
atherosclerosis
304
ischemia
257
melanoma
230
breast cancer
222
diabetes
220
pulmonary embolism
215
PCL
208
hypertension
206
carcinoma
200
SEM
188
cardiovascular disease
166
deep vein thrombosis
143
tumor growth
139
disseminated intravascular coagulation
127
metastases
122
hepatocellular carcinoma
119
coronary artery disease
113
plaque
113
cerebral ischemia
111
PGA
110
MCF
104
sepsis
102
obesity
97
sepsis
92
coronary heart disease
91
coronary thrombosis
88
Yersinia
77
Alzheimer's disease
76
myocardial ischemia
72
Thrombus
68
adenocarcinoma
67
heart failure
65
cerebral infarction
65
vascular disease
65
leukemia
65
systemic lupus erythematosus
64
coagulopathy
64
glioma
63
rheumatoid arthritis
63
TEM
60
unstable angina
60
fibrosarcoma
60
TEM
59
arthritis
59
thrombocytopenia
57
squamous cell carcinoma
56
cold
55
lung cancer
55
tumor progression
55
IVA
54
cirrhosis
52
prostate cancer
51
LAP
51
depression
50
type 2 diabetes
49
carcinogenesis
48
Rous sarcoma
45
colon cancer
44
pertussis
43
plague
42
lupus
42
neurological disease
42
ovarian cancer
42
uterus
42
renal disease
41
multiple sclerosis
39
neuroblastoma
39
pulmonary hypertension
38
pneumonia
38
glioblastoma
38
multiple myeloma
37
lung carcinoma
37
preeclampsia
37
hyperlipidemia
37
embryonal carcinoma
36
lupus
36
colorectal cancer
36
sarcoma
35
membranous nephropathy
34
asthma
34
osteosarcoma
34
hyperglycemia
34
Acute Stroke
34
tumorigenesis
34
hypercholesterolemia
33
gastric cancer
33
osteoarthritis
33
venous stasis
32
HIV
32
TCP
32
cholera
32
Ischemic stroke
32
PAF
30
PLG
29
congestive heart failure
29
glomerulonephritis
29
cornea
28
GSH
28
coronary occlusion
28
mole
28
infectious diseases
28
von Willebrand disease
27
NAME
27
proteinuria
26
metabolic syndrome
26
pemphigus
25
liver disease
25
mole
25
Adhesion
25
hemiparesis
25
psoriasis
24
encephalomyelitis
24
dementia
24
primary tumor
23
essential hypertension
23
lymphoma
23
renal failure
22
tumor angiogenesis
22
hyperinsulinemia
22
brain edema
21
dyslipidemia
21
heart disease
20
liver cancer
20
hypofibrinogenemia
19
subarachnoid hemorrhage
19
pulmonary fibrosis
19
epithelial ovarian cancer
19
tetanus
19
PLAT
19
nephrotic syndrome
19
brain tumor
19
infertility
19
haemophilia
19
pancreatic cancer
18
arteriosclerosis
18
liver cancer
18
cytomegalovirus
18
coma
18
retinopathy
18
bacterial infection
18
adult respiratory distress syndrome
18
transient ischemic attack
17
aqueous humor
17
acute promyelocytic leukemia
17
aphasia
17
antiphospholipid syndrome
17
non-small cell lung cancer
17
abortion
17
immunodeficiency
17
PHA
16
Steroids
16
amyloidosis
16
anaphylaxis
16
meningitis
16
more...
Symptom
pain
97
chest pain
73
angina
64
anesthesia
40
functional recovery
33
fatigue
32
exhaustion
31
collapse
30
respiratory distress
26
seizures
26
overweight
25
hypothermia
20
dyspnea
19
discomfort
13
discomfort
12
flushing
12
hemiplegia
12
shortness of breath
11
weakness
11
spasm
10
nausea
9
headache
9
acidity
9
thinning
9
starvation
8
tremor
8
abdominal pain
8
syncope
7
dysarthria
7
tachypnea
7
diarrhea
6
cough
6
numbness
6
vertigo
6
ataxia
6
stigma
6
analgesia
6
pelvic pain
5
agitation
5
sleepiness
5
consciousness disturbance
5
hyperoxia
5
vomiting
5
cyanosis
4
dizziness
4
acute stress
4
disturbed balance
4
hepatomegaly
4
livedo
4
skin damage
4
regurgitation
4
arm pain
3
paresis
3
exertional dyspnea
3
neurological disability
3
Fluctuation
3
back pain
3
hemoptysis
3
myalgia
3
sneezing
2
ENT
2
paraparesis
2
splenomegaly
2
nasal discharge
2
productive cough
2
acute abdominal pain
2
tinnitus
2
erythema
2
incoordination
2
hypercapnia
2
cachexia
2
acute pain
2
abdominal discomfort
2
leg pain
2
skin irritation
2
low back pain
2
Livedoid
1
catatonia
1
rigors
1
neck pain
1
pedal edema
1
dysesthesia
1
pleuritic chest pain
1
general problem
1
cardialgia
1
CSR
1
Gastrointestinal symptoms
1
physical appearance
1
night sweats
1
exertional angina
1
scaly skin
1
constipation
1
urological problem
1
skin irritant
1
rhinorrhea
1
GI irritation
1
anorexia
1
intestinal bleeding
1
Anoxia
1
dystonia
1
Ill
1
Neuropathic pain
1
Involuntary Movement
1
facial pain
1
fasciculation
1
asthenia
1
Muscle soreness
1
Severe pain
1
mental fatigue
1
sore throat
1
memory loss
1
flank pain
1
presyncope
1
distraction
1
dry eye
1
Wind
1
POA
1
hepatosplenomegaly
1
twitching
1
orofacial pain
1
hunger
1
leg edema
1
hypotonia
1
nausea and vomiting
1
Scratch
1
atypical chest pain
1
autodigestion
1
epigastric pain
1
Drug
lysine
365
uPA
364
Alteplase
173
Alteplase
156
Alteplase
151
Cardiovasc
147
Urokinase
134
Streptokinase
102
Dermatol
75
DDAVP
60
DDAVP
59
Gel
51
Asn
47
MAP
30
Tenecteplase
30
DFP
29
vitamin E
29
ROS
25
TAT
25
CSF
24
Taxol
23
nitroglycerin
23
caffeine
21
CaCl2
19
CaCl2
19
CaCl2
19
Aprotinin
19
Nephron
18
ascorbate
18
Dial
18
THF
17
ZnO
17
Retinoic acid
17
lactose
16
Docetaxel
16
Activase
15
EE2
15
CTA
15
IFN-gamma
15
Argatroban
14
Nephron
14
Indomethacin
14
IL-2
12
EPA
12
Angiotensin II
11
Vitamin E
11
ABC
11
PPA
11
Ancrod
10
ACT
10
ADR
10
citric acid
10
Monit
10
Cremophor EL
9
Taxotere
9
Fragment
9
Captopril
9
G418
9
Dalteparin
9
Lactic Acid
9
Biopolymers
8
Gelatin
8
FeCl3
8
PTH
8
Forskolin
8
Simvastatin
7
ROC
7
DNase I
7
Antithrombin III
7
Desmoteplase
7
Tacrolimus
7
Leaf
7
Albumin
7
ALA
7
Darapladib
7
GEO
6
ENT
6
TiO2
6
Fraction
6
p75
6
Coumadin
6
Vitamin A
6
Lanoteplase
6
Norplant
5
PCB
5
Triad
5
Fragmin
5
MRC
5
Vena
5
RFP
5
Herceptin
5
Histamine
5
Vena
5
PDL
5
G-CSF
5
TMS
5
Diphenhydramine
5
Fluorescein
5
Hirulog
5
Abciximab
5
Ximelagatran
5
SiO2
5
Clopidogrel
5
Lovastatin
5
balanced salt solution
5
Pamiteplase
5
ICI
4
Doxycycline
4
DEX
4
Ginseng
4
Glycerol
4
Gabapentin
4
CAM
4
Gemfibrozil
4
ADM
4
Spectrum
4
Optison
4
PTC
4
GHRP
4
Alanine
4
DMAP
4
Fluorescein
4
Warfarin sodium
4
Ethanol
4
Vitamin K
4
TTC
3
Bayer
3
Trental
3
Arlacel 83
3
Imiquimod
3
Iloprost
3
Growth hormone
3
Pravastatin
3
niacin
3
Naproxen sodium
3
Asthma
3
CTX
3
NVP
3
Wine
3
Poloxamer
3
Alliance
3
TAC
3
Everolimus
3
NAG
3
Ziagen
3
CCL
3
EPI
3
Amiloride
3
BLM
3
NH3
3
KGF
3
Growth hormone
3
Monteplase
3
Fondaparinux
3
Amiloride
3
Lipidex
3
CTX
3
Glucagon
3
Heparin sodium
3
CTX
3
more...
Enzyme
tissue plasminogen activator
5663
urokinase-type plasminogen activator
2635
plasmin
1891
phospholipase A2
1375
thrombin
922
ERK
308
thromboplastin
266
APC
248
trypsin
246
collagenase
193
mitogen-activated protein kinase
192
protein kinase C
187
ACS
132
kallikrein
124
elastase
114
protein kinase
113
alkaline phosphatase
86
peroxidase
82
phospholipase C
80
lipoxygenase
61
MMP-3
61
creatine kinase
59
ACE
57
renin
57
focal adhesion kinase
55
chymotrypsin
50
superoxide dismutase
49
lipase
49
lysozyme
47
thrombin-activatable fibrinolysis inhibitor
46
lactate dehydrogenase
42
phospholipase D
39
phosphodiesterase
38
matrix metalloproteinase 2
37
cathepsin B
36
cathepsin D
35
MEK
34
cathepsin G
33
catalase
33
adenylate cyclase
33
caspase-3
32
reverse transcriptase
32
NADPH oxidase
31
MMP
29
matrix metalloproteinase 9
28
NO synthase
26
luciferase
26
ATPase
26
NADPH oxidase
26
beta-glucuronidase
26
transglutaminase
25
hyaluronidase
25
TAT
25
Pla
25
neutrophil elastase
24
interstitial collagenase
24
acid phosphatase
24
lipoprotein lipase
22
carboxypeptidase B
22
hyaluronidase
22
proteinase K
22
ancrod
21
enolase
19
neuropathy target esterase
19
tryptase
18
deaminase
18
beta-galactosidase
18
ornithine decarboxylase
18
Hageman factor
16
tissue kallikrein
15
AMPK
15
alanine aminotransferase
14
DNase
14
P-glycoprotein
14
glutathione S-transferase
13
heparinase
13
proteasome
13
glutathione peroxidase
13
phosphatidylinositol 3-kinase
12
RNase
12
glyceraldehyde-3-phosphate dehydrogenase
12
subtilisin
12
dihydrofolate reductase
11
guanylate cyclase
11
RNase
11
neuraminidase
11
xanthine oxidase
11
acetylcholinesterase
11
aspartate aminotransferase
11
5'-nucleotidase
11
RNA polymerase
10
PARP
10
PRA
10
calcineurin
9
pepsin
9
papain
9
prostate-specific membrane antigen
9
MAP
9
carboxylesterase
8
NOS
8
12-lipoxygenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
CD10
7
chloramphenicol acetyltransferase
7
phosphoinositide 3-kinase
7
apyrase
7
glyceraldehyde-3-phosphate dehydrogenase
7
PNGase F
7
chymase
7
15-lipoxygenase
7
glyceraldehyde-3-phosphate dehydrogenase
7
thromboxane synthase
7
transcriptase
7
hexosaminidase
7
PTA
7
tyrosinase
7
glyceraldehyde-3-phosphate dehydrogenase
7
BMT
6
MDP
6
CAD
6
cathepsin L
6
IKK
6
PAL
6
gamma-glutamyl transpeptidase
6
glutamine synthetase
6
phospholipase A1
6
CAD
6
thymidine kinase
6
CAD
6
clotting enzyme
6
PDE
6
prostaglandin synthetase
6
S1 nuclease
6
endonuclease
6
asparaginase
6
PAL
6
endoglycosidase H
6
paraoxonase
5
BAL
5
CD13
5
lysin
5
caspase-9
5
sialidase
5
cutinase
5
cholinesterase
5
MDR
5
AST
5
paraoxonase
5
GAS
5
NQO1
5
methylenetetrahydrofolate reductase
4
ATP synthase
4
ADPase
4
ribonuclease
4
ribonuclease
4
lecithin:cholesterol acyltransferase
4
monoacylglycerol lipase
4
Alternating
4
thermolysin
4
ricin
4
more...
Compound
PLA
6020
Dec
1239
PEG
865
PEG
790
Clin
658
water
652
calcium
557
lysine
532
DNA
528
serine
413
sodium
412
Cardiol
361
arginine
355
oxygen
351
acetate
338
SDS
327
sulfate
287
phosphate
276
glucose
269
Lactic acid
196
Plasmin
194
ACS
188
prostacyclin
162
Fibrin
154
cAMP
148
nitric oxide
141
ADP
137
retinoic acid
134
ACS
132
Asp
124
alanine
122
tyrosine
120
Fibrinogen
118
hydrogen
118
Gly
118
PGA
116
ADP
115
His
115
ADP
115
cysteine
114
Thrombin
112
PGE
109
bromide
107
salt
104
leucine
104
MTT
102
TNF
101
Heparin
98
zinc
93
galactose
91
Phe
90
TEM
85
AMP
85
iron
83
ethanol
83
methionine
81
EDTA
78
copper
77
CO2
75
ATP
74
ASA
72
EDTA
71
TOF
71
nitrogen
70
FDP
68
MDA
67
ammonium
63
Triton X-100
62
urea
62
NH2
62
vinyl
57
PVA
54
carbonate
54
glutamate
53
dichloromethane
51
glutamic acid
51
creatinine
50
glycerol
50
Cereb
50
PAR
49
Insulin
48
adipate
45
threonine
45
potassium
44
nitrate
42
TPA
41
PMA
40
PHB
40
chloroform
40
acetone
40
TPA
40
Pluronic
40
Dexamethasone
39
silver
38
PMA
37
HCl
37
tryptophan
37
Ile
37
hyaluronic acid
37
homocysteine
35
PGE2
35
6-aminohexanoic acid
35
6-aminohexanoic acid
35
Paclitaxel
35
Arachidonic acid
34
THP
34
tin
34
iodine
34
aspartic acid
34
THP
34
proline
33
tryptophan
32
NMDA
32
TCP
32
TCP
32
tryptophan
32
tryptophan
32
TCP
32
TCP
32
DEAE
32
GSH
31
GSH
31
Tris
30
aspartic acid
30
methanol
29
thioglycollate
29
ADR
29
Ang II
29
Tranexamic acid
29
glutamine
29
Serine
28
acetic acid
28
H2O2
28
acrylamide
28
aspartic acid
28
THF
28
aspartic acid
27
guanidine
27
prostaglandin E1
27
PEI
26
PEI
26
COS
26
titanium
25
aluminum
25
aldosterone
25
DIC
24
5-HT
24
cGMP
23
Optimal
23
phenol
23
ammonia
22
Estrogen
22
ethyl acetate
22
Phorbol
22
silicon
21
isopropanol
21
DMSO
21
caffeine
21
COX
21
Angiotensin II
21
more...