Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P00750 (PLA)
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Up to 2000 Australians each year rupture a cerebral aneurysm. This is immediately fatal in some, and others remain disabled. The main risks after a first haemorrhage are recurrent bleeding, prevented by early surgery, and delayed cerebral ischaemia due to vasospasm. This is minimised by keeping a good fluid balance, calcium antagonists, and possibly newer treatments such as aminosteroids or plasminogen activator. An important problem is that of the missed haemorrhage, which often leads to delay in treatment and a fatal or disabling recurrence.
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PMID:Cerebral aneurysms and subarachnoid haemorrhage. 145 Jun 43