Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P00750 (PLA)
 16,800 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Examination of 107 patients that had undergone radical correction of tetralogy of Fallot using computer monitoring and mathematical modelling of circulation showed that right-ventricular failure was characterized by reduced cardiac output, high central venous pressure at relatively low left-ventricular pressures, high PV-PLA gradient at low pumping function of the right ventricle. An increase in the volume load in right-ventricular failure may lead to suppressed pumping function of the right heart. Thus, infusion therapy should be administered in relation to the PV-PLA gradient and its changes with increased adrenomimetic doses. Replacing assisted ventilation by spontaneous breathing should be accomplished in these patients using the technique of intermittent forced lung ventilation which is most optimal.
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PMID:[Principles of the diagnosis and intensive therapy of right ventricular insufficiency in patients following radical correction of Fallot's tetralogy]. 259 92