Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P00492 (hypoxanthine-guanine phosphoribosyltransferase)
 2,385 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
hypoxanthine-guanine phosphoribosyltransferase 0.999
HPRT 0.016
hypoxanthine guanine phosphoribosyltransferase 0.002
aprt 0.002
IMP 0.001
purine nucleoside phosphorylase 0.001
adenosine kinase 0.001
WEE1 homolog 0.001
60S ribosomal protein L13 0.001
TOP2 beta 0.001
phosphoglycerate kinase 0.000
X-linked 0.000
GMP 0.000
HAT 0.000
amidophosphoribosyltransferase 0.000
60S ribosomal protein L32 0.000
guanine deaminase 0.000
MAE3 0.000
Calsyntenin-3 0.000
Neurexophilin 1 0.000
neurexophilin 3 0.000
adenylosuccinate synthetase 0.000
AMP 0.000
NPH2 0.000
Tp120 0.000
PRTFDC1 0.000
engrailed homeobox 1 0.000
Inosine 5'-monophosphate dehydrogenase 0.000
PPRibP 0.000
X-linked recessive 0.000
adenosine deaminase 0.000
V3-3 0.000
Mvp1 0.000
neurexophilin 1 0.000
thymidine kinase 0.000
succinate dehydrogenase complex subunit A 0.000
40S ribosomal protein S12 0.000
ALDH16A1 0.000
X-chromosome 0.000
60S acidic ribosomal protein P0 0.000
RML2 0.000
XMP 0.000
Adapter protein 0.000
cadherin-9 0.000
Cysteine conjugate beta-lyase 0.000
adenylosuccinate synthase 0.000
adenylosuccinate lyase 0.000
glucose-6-phosphate dehydrogenase 0.000
GUK1 0.000
PSA2 0.000
selenium binding protein 1 0.000
nicotinic acid phosphoribosyltransferase 0.000
ribosomal protein L8 0.000
hypoxanthine phosphoribosyltransferase 1 0.000
MDR/TAP 0.000
GMP reductase 0.000
nucleoside phosphorylase 0.000
C8G 0.000
VDAC-2 0.000
A-9 0.000
AHH 0.000
acyl-protein thioesterase 0.000
Guanine deaminase 0.000
LTV1 0.000
deoxyguanosine kinase 0.000
LRRTM2 0.000
CDH10 0.000
ADORA2A 0.000
AMP deaminase 0.000
Deoxyguanosine kinase 0.000
THO2 0.000
phosphoribosyl pyrophosphate amidotransferase 0.000
xanthine oxidase 0.000
DRP2 0.000
5'-nucleotidase 0.000
BGR 0.000
UV20 0.000
SULT1C2 0.000
MCL 0.000
Sp5 0.000
more...
Disease
Lesch-Nyhan syndrome 0.203
Kelley-Seegmiller syndrome 0.002
hyperuricemia 0.001
self-injurious behavior 0.001
choreoathetosis 0.001
Hyperuricemic nephropathy 0.001
Deficiency of uracil phosphoribosyltransferase 0.001
Disorders of purine and pyrimidine metabolism 0.001
gout 0.000
UMP synthase deficiency 0.000
enzyme deficiency 0.000
purine metabolism disorder 0.000
APRT deficiency 0.000
PNP deficiency 0.000
Marie's ataxia 0.000
gouty nephropathy 0.000
glycinuria 0.000
carcinogenesis 0.000
mental retardation 0.000
mental retardation 0.000
MCL 0.000
uricosuria 0.000
xeroderma pigmentosum 0.000
nephrolithiasis 0.000
self-destructive behavior 0.000
ADA deficiency 0.000
adult soft tissue sarcoma 0.000
articulation disorder 0.000
tophi 0.000
cystathioninuria 0.000
nervous disorder 0.000
disorders of amino acid metabolism 0.000
cancer 0.000
neurobehavioral problems 0.000
AT3 0.000
AT3 0.000
AT3 0.000
AT3 0.000
AT3 0.000
AT3 0.000
AT3 0.000
AT3 0.000
AT3 0.000
18q- syndrome 0.000
CEM 0.000
Tay-Sachs disease 0.000
acute promyelocytic leukemia 0.000
Schistosoma mansoni 0.000
DRD 0.000
orotic aciduria 0.000
familial disorder 0.000
XPD 0.000
megaloblastic anemia 0.000
sponge kidney 0.000
mantle cell lymphoma 0.000
Fukuyama congenital muscular dystrophy 0.000
mouse leukemia L1210 0.000
Bradley 0.000
secondary AML 0.000
nephrocalcinosis 0.000
abnormal involuntary movements 0.000
STY 0.000
hyperargininemia 0.000
embryonal carcinoma 0.000
lymphoma 0.000
fragile X syndrome 0.000
dyserythropoietic anemia 0.000
genetic disorder 0.000
Cockayne syndrome 0.000
Papillomas 0.000
cerebral palsy 0.000
hypobetalipoproteinemia 0.000
XX males 0.000
chronic myeloproliferative disorders 0.000
congenital hemolytic anemia 0.000
CPL 0.000
leukemia 0.000
CAE 0.000
urolithiasis 0.000
Fanconi 0.000
more...
Symptom
athetosis 0.000
spasticity 0.000
dystonia 0.000
chromosome marker 0.000
labored breathing 0.000
clumsiness 0.000
chorea 0.000
renal colic 0.000
Decreased activity 0.000
hypertonia 0.000
Fluctuation 0.000
forgetfulness 0.000
dysesthesia 0.000
muscle stiffness 0.000
hypotonia 0.000
starvation 0.000
dysarthria 0.000
flank pain 0.000
stridor 0.000
dysuria 0.000
vomiting 0.000
HSA 0.000
colic 0.000
myoclonus 0.000
tremor 0.000
acute stress 0.000
hyperoxia 0.000
lethargy 0.000
hepatomegaly 0.000
paresis 0.000
hemoptysis 0.000
ataxia 0.000
splenomegaly 0.000
sleepiness 0.000
seizures 0.000
abdominal pain 0.000
pain 0.000
weakness 0.000
respiratory distress 0.000
nausea 0.000
overweight 0.000
anesthesia 0.000
dyspnea 0.000
analgesia 0.000
collapse 0.000
fatigue 0.000
diarrhea 0.000
Drug
Mutagen 0.000
Thioguanine 0.000
6-Methylpurine 0.000
2-Methoxyethanol 0.000
Adenosine deaminase 0.000
8-Azaguanine 0.000
Adozelesin 0.000
G418 0.000
BH4 0.000
Formycin B 0.000
Mercaptopurine 0.000
Neocarzinostatin 0.000
TMX 0.000
Rasburicase 0.000
Rasburicase 0.000
Deoxyadenosine 0.000
Febuxostat 0.000
Adderall 0.000
Cytidine 0.000
Propidium 0.000
Acyclovir 0.000
Cellulose acetate 0.000
KCL 0.000
Etoposide 0.000
Mycophenolic acid 0.000
AGG 0.000
Adriamycin 0.000
AZT 0.000
ddI 0.000
OMP 0.000
AZT 0.000
-deoxyadenosine 0.000
DNase I 0.000
AIC 0.000
ACT 0.000
CFT 0.000
Helium 0.000
caffeine 0.000
Reserpine 0.000
Prednisone 0.000
CTC 0.000
AraC 0.000
TAT 0.000
Hypaque 0.000
Infliximab 0.000
Infliximab 0.000
Hypaque 0.000
Arsenic trioxide 0.000
CTC 0.000
IFN-beta 0.000
BLM 0.000
Meth 0.000
Sorafenib 0.000
MIL 0.000
Parkin 0.000
Parkin 0.000
lysine 0.000
THF 0.000
IFN-gamma 0.000
ICI 0.000
Ouabain 0.000
Nitric Oxide 0.000
ETS 0.000
Alanine 0.000
Asn 0.000
Vitamin E 0.000
Kenyan 0.000
p75 0.000
nitroglycerin 0.000
Spectrum 0.000
Ethanol 0.000
Nephron 0.000
CSF 0.000
Glutathione 0.000
FAD 0.000
Bifidobacterium 0.000
CaCl2 0.000
CaCl2 0.000
CaCl2 0.000
Gel 0.000
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase 0.361
adenine phosphoribosyltransferase 0.011
xanthine phosphoribosyltransferase 0.002
purine nucleoside phosphorylase 0.001
PRPP synthetase 0.001
amidophosphoribosyltransferase 0.001
adenosine kinase 0.000
phosphoglycerate kinase 0.000
adenylosuccinate synthetase 0.000
adenine deaminase 0.000
IMP dehydrogenase 0.000
formyltetrahydrofolate deformylase 0.000
adenosine deaminase 0.000
guanase 0.000
adenosine deaminase 0.000
thymidine kinase 0.000
orotate phosphoribosyltransferase 0.000
adenylosuccinate lyase 0.000
acyl-CoA:malonyl-CoA C-acyltransferase 0.000
glucose-6-phosphate dehydrogenase 0.000
AMP deaminase 0.000
nicotinic acid phosphoribosyltransferase 0.000
3-methyladenine DNA glycosylase I 0.000
deoxyadenosine kinase 0.000
5'-nucleotidase 0.000
deoxyguanosine kinase 0.000
GMP synthetase 0.000
GMP reductase 0.000
AICAR transformylase 0.000
EC 1.3.2.3 0.000
xanthine oxidase 0.000
orotidine-5'-phosphate decarboxylase 0.000
PRT 0.000
IMP cyclohydrolase 0.000
DHOdehase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
alpha-galactosidase 0.000
GMP synthase 0.000
deoxycytidine kinase 0.000
methylthioadenosine phosphorylase 0.000
nucleoside phosphotransferase 0.000
3-hydroxyanthranilic acid oxygenase 0.000
glycinamide ribonucleotide transformylase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
CMP kinase 0.000
deoxycytidine deaminase 0.000
porphobilinogen deaminase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
deoxyribonuclease 0.000
S-adenosyl-L-homocysteine hydrolase 0.000
adenylate kinase 0.000
thymidylate kinase 0.000
nicotinamide mononucleotide adenylyltransferase 0.000
tripeptidase 0.000
uridine phosphorylase 0.000
xanthine dehydrogenase 0.000
thiopurine methyltransferase 0.000
endonuclease V 0.000
galactokinase 0.000
phosphomannose isomerase 0.000
guanylate kinase 0.000
nucleoside diphosphokinase 0.000
NMT 0.000
deaminase 0.000
3'-phosphatase 0.000
AGT 0.000
cyclohydrolase 0.000
uracil phosphoribosyltransferase 0.000
EC 1.1.1.40 0.000
uridine kinase 0.000
cytidine deaminase 0.000
pantothenate kinase 0.000
nucleotidase 0.000
CPL 0.000
DOPA decarboxylase 0.000
ADH3 0.000
alanine dehydrogenase 0.000
SpeB 0.000
more...
Compound
IMP 0.001
Hypoxanthine 0.001
6-Ethylmercaptopurine 0.001
1-(3-pyridinyl)-2-butanone 0.001
C10H12N4O5S 0.000
GMP 0.000
6-Thioguanine 0.000
methoxyacetaldehyde 0.000
Purine 0.000
Marmesin 0.000
C7H8N4S 0.000
1,3-Butadiene 0.000
PRPP 0.000
DNA 0.000
Disperse Red 11 0.000
R 48 0.000
Marmesin 0.000
6-Mercaptopurine riboside 0.000
R 7000 0.000
XMP 0.000
Tiazofurin 0.000
Xanthine 0.000
Inosinic acid 0.000
6-Methylpurine 0.000
1,8-Dinitropyrene 0.000
Ammonium metavanadate 0.000
6-Methylpurine 0.000
1,2-butanediol 0.000
Myosmine 0.000
Cryptolepine 0.000
N-Hydroxy-2-acetylaminofluorene 0.000
Orotidine 0.000
Prunetin 0.000
pyrene 0.000
Inosine 0.000
1,6-Dinitropyrene 0.000
WR-1065 0.000
pyrimidine 0.000
pyrimidine 0.000
EMS 0.000
dGTP 0.000
6-Mercaptopurine 0.000
methyl methanesulfonate 0.000
ENNG 0.000
Aminoimidazole 0.000
1H-phenalen-1-one 0.000
HPP 0.000
Metanephrine 0.000
HNS 0.000
Bathocuproine 0.000
Lead nitrate 0.000
N-ethylurea 0.000
Formycin B 0.000
Formycin B 0.000
dGDP 0.000
PPi 0.000
Glycidol 0.000
5H-pyrido[4,3-b]indole 0.000
CI-921 0.000
3-aminobenzamide 0.000
Normetanephrine 0.000
TGR 0.000
Neocarzinostatin 0.000
ENU 0.000
7H-dibenzo[c,g]carbazole 0.000
Adenine 0.000
Diepoxybutane 0.000
isopropyl acetate 0.000
GTP 0.000
Kojic acid 0.000
AMP 0.000
PhIP 0.000
Potassium bromate 0.000
4-NQO 0.000
2-ethylhexyl acrylate 0.000
2-methoxyethanol 0.000
NaAsO2 0.000
Phenolphthalein 0.000
methoxyacetic acid 0.000
Phenolphthalein 0.000
more...