Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P00492 (hypoxanthine-guanine phosphoribosyltransferase)
 2,385 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
hypoxanthine-guanine phosphoribosyltransferase 13.7
WEE1 homolog 13.7
60S ribosomal protein L13 13.7
TOP2 beta 12.4
60S ribosomal protein L32 12.1
MAE3 11.7
neurexophilin 3 11.7
Calsyntenin-3 11.7
Neurexophilin 1 11.7
PPRibP 11.4
NPH2 11.4
PRTFDC1 11.4
engrailed homeobox 1 11.4
Tp120 11.4
aprt 11.2
hypoxanthine guanine phosphoribosyltransferase 11.2
Mvp1 11.1
neurexophilin 1 11.1
V3-3 11.1
HPRT 11.0
40S ribosomal protein S12 10.9
ALDH16A1 10.9
RML2 10.7
60S acidic ribosomal protein P0 10.7
Adapter protein 10.5
cadherin-9 10.5
succinate dehydrogenase complex subunit A 10.5
Cysteine conjugate beta-lyase 10.4
Inosine 5'-monophosphate dehydrogenase 10.1
adenylosuccinate synthase 10.1
GUK1 10.0
PSA2 10.0
selenium binding protein 1 10.0
ribosomal protein L8 9.9
guanine deaminase 9.8
amidophosphoribosyltransferase 9.8
MDR/TAP 9.7
hypoxanthine phosphoribosyltransferase 1 9.6
VDAC-2 9.5
C8G 9.5
adenylosuccinate synthetase 9.5
GMP reductase 9.4
nicotinic acid phosphoribosyltransferase 9.3
Guanine deaminase 9.3
LTV1 9.3
acyl-protein thioesterase 9.3
LRRTM2 9.2
purine nucleoside phosphorylase 9.2
CDH10 9.2
THO2 9.1
Deoxyguanosine kinase 9.1
phosphoribosyl pyrophosphate amidotransferase 9.1
XMP 9.1
DRP2 9.1
SULT1C2 9.0
BGR 9.0
UV20 9.0
A-9 9.0
adenosine kinase 9.0
ANXA11 8.9
NPH4 8.9
70kD 8.8
3-hydroxyanthranilate 3,4-dioxygenase 8.8
adenylosuccinate lyase 8.8
IMP 8.8
Sp5 8.7
SULT1B1 8.7
THH 8.7
dGK 8.7
14-3-3 epsilon protein 8.7
mannose phosphate isomerase 8.7
mutS homolog 6 8.7
BTF2 8.7
ADORA2A 8.6
LAMR1 8.6
ribosomal protein L13a 8.6
Beta-secretase 8.6
deoxyguanosine kinase 8.6
CAD protein 8.5
ribosomal protein P0 8.5
more...
Disease
Disorders of purine and pyrimidine metabolism 13.7
Deficiency of uracil phosphoribosyltransferase 13.7
Hyperuricemic nephropathy 13.7
Lesch-Nyhan syndrome 13.3
Kelley-Seegmiller syndrome 13.1
UMP synthase deficiency 12.1
purine metabolism disorder 10.9
Marie's ataxia 10.1
glycinuria 9.7
APRT deficiency 9.7
gouty nephropathy 9.6
PNP deficiency 9.5
choreoathetosis 9.4
self-injurious behavior 9.2
uricosuria 8.4
adult soft tissue sarcoma 8.4
hyperuricemia 8.4
articulation disorder 8.2
self-destructive behavior 8.0
enzyme deficiency 7.9
cystathioninuria 7.9
nervous disorder 7.8
ADA deficiency 7.6
gout 7.5
disorders of amino acid metabolism 7.4
MCL 7.4
neurobehavioral problems 7.3
18q- syndrome 7.1
tophi 7.1
AT3 7.1
AT3 7.1
AT3 7.1
AT3 7.1
AT3 7.1
AT3 7.1
AT3 7.1
AT3 7.1
AT3 7.1
orotic aciduria 6.8
DRD 6.8
familial disorder 6.6
sponge kidney 6.6
Fukuyama congenital muscular dystrophy 6.5
mouse leukemia L1210 6.5
nephrolithiasis 6.4
STY 6.4
xeroderma pigmentosum 6.4
hyperargininemia 6.3
dyserythropoietic anemia 6.2
Papillomas 6.1
hypobetalipoproteinemia 6.1
Bradley 6.0
secondary AML 6.0
XX males 6.0
XPD 6.0
abnormal involuntary movements 6.0
congenital hemolytic anemia 6.0
CPL 5.9
Tay-Sachs disease 5.9
chronic myeloproliferative disorders 5.8
CAE 5.8
megaloblastic anemia 5.7
CAE 5.7
nephrocalcinosis 5.5
Cockayne syndrome 5.5
spastic diplegia 5.5
mental retardation 5.4
mental retardation 5.4
thyroid neoplasm 5.4
MNS 5.4
XPB 5.3
dissociative disorder 5.3
malignant state 5.3
CEM 5.3
Severe sepsis 5.2
CREST 5.2
Lowe syndrome 5.2
trichothiodystrophy 5.2
SD1 5.2
harlequin 5.2
more...
Symptom
athetosis 8.3
chromosome marker 6.6
labored breathing 6.0
spasticity 6.0
clumsiness 5.6
renal colic 5.0
dystonia 4.8
chorea 4.7
Decreased activity 4.6
Fluctuation 4.5
hypertonia 4.4
forgetfulness 4.3
dysesthesia 3.8
muscle stiffness 3.4
dysarthria 2.8
hypotonia 2.8
flank pain 2.6
stridor 2.5
dysuria 2.4
HSA 2.2
colic 2.1
starvation 1.9
myoclonus 1.6
acute stress 1.5
hyperoxia 1.4
vomiting 1.3
lethargy 1.2
hepatomegaly 1.2
paresis 1.2
hemoptysis 1.1
tremor 1.1
ataxia 0.7
splenomegaly 0.4
sleepiness 0.1
abdominal pain -0.2
weakness -0.5
respiratory distress -0.6
seizures -0.6
nausea -0.8
overweight -1.0
dyspnea -1.1
analgesia -1.1
collapse -1.1
anesthesia -1.5
pain -1.5
fatigue -2.0
diarrhea -2.1
Drug
6-Methylpurine 10.4
Thioguanine 10.2
2-Methoxyethanol 9.1
8-Azaguanine 9.0
Adozelesin 8.9
Formycin B 8.5
Mercaptopurine 8.3
Neocarzinostatin 7.9
Mutagen 7.5
Adenosine deaminase 7.5
TMX 7.4
Rasburicase 7.3
BH4 6.8
Deoxyadenosine 6.8
Rasburicase 6.7
G418 6.6
Febuxostat 6.5
Adderall 6.4
Cytidine 5.8
Propidium 5.7
Cellulose acetate 5.6
KCL 5.6
Mycophenolic acid 5.3
Acyclovir 5.3
Etoposide 5.1
AGG 5.1
ddI 4.9
OMP 4.8
AIC 4.7
CFT 4.5
Helium 4.5
AZT 4.3
-deoxyadenosine 4.3
ACT 4.2
AZT 4.1
Adriamycin 4.1
Reserpine 3.7
Prednisone 3.7
CTC 3.7
AraC 3.7
Hypaque 3.6
Infliximab 3.6
Infliximab 3.6
DNase I 3.5
TAT 3.5
Hypaque 3.4
Arsenic trioxide 3.4
CTC 3.4
BLM 3.3
Meth 3.3
IFN-beta 3.1
Sorafenib 3.1
MIL 3.1
Parkin 2.8
Parkin 2.8
caffeine 2.5
Ouabain 2.4
Nitric Oxide 2.4
ETS 2.3
ICI 2.3
THF 2.3
Alanine 2.3
Vitamin E 2.0
Kenyan 1.9
p75 1.8
Asn 1.8
Spectrum 1.7
nitroglycerin 1.6
IFN-gamma 1.5
Ethanol 1.4
Glutathione 1.3
FAD 1.3
lysine 1.2
Bifidobacterium 1.2
Nephron 1.2
CaCl2 1.1
CaCl2 1.1
CaCl2 1.0
NH3 0.9
Gel 0.8
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase 12.9
xanthine phosphoribosyltransferase 11.6
formyltetrahydrofolate deformylase 11.4
adenine phosphoribosyltransferase 11.3
amidophosphoribosyltransferase 10.5
PRPP synthetase 10.2
adenine deaminase 10.0
acyl-CoA:malonyl-CoA C-acyltransferase 10.0
3-methyladenine DNA glycosylase I 9.6
adenylosuccinate synthetase 9.6
purine nucleoside phosphorylase 9.3
deoxyadenosine kinase 9.3
guanase 9.2
EC 1.3.2.3 9.1
nicotinic acid phosphoribosyltransferase 9.1
adenylosuccinate lyase 9.0
GMP reductase 8.9
AICAR transformylase 8.9
adenosine kinase 8.8
orotate phosphoribosyltransferase 8.6
deoxyguanosine kinase 8.5
IMP dehydrogenase 8.5
GMP synthetase 8.5
IMP cyclohydrolase 8.4
DHOdehase 8.3
phosphoglycerate kinase 8.0
GMP synthase 7.9
orotidine-5'-phosphate decarboxylase 7.9
PRT 7.9
AMP deaminase 7.9
nucleoside phosphotransferase 7.8
3-hydroxyanthranilic acid oxygenase 7.7
glycinamide ribonucleotide transformylase 7.5
methylthioadenosine phosphorylase 7.4
CMP kinase 7.4
deoxycytidine deaminase 7.3
adenosine deaminase 7.1
adenosine deaminase 7.0
deoxycytidine kinase 6.8
nicotinamide mononucleotide adenylyltransferase 6.7
thymidine kinase 6.7
tripeptidase 6.7
5'-nucleotidase 6.7
S-adenosyl-L-homocysteine hydrolase 6.6
thymidylate kinase 6.5
endonuclease V 6.5
uridine phosphorylase 6.4
porphobilinogen deaminase 6.4
nucleoside diphosphokinase 6.4
NMT 6.3
3'-phosphatase 6.3
alpha-galactosidase 6.3
phosphomannose isomerase 6.2
glucose-6-phosphate dehydrogenase 6.2
guanylate kinase 6.2
thiopurine methyltransferase 6.2
uracil phosphoribosyltransferase 6.0
EC 1.1.1.40 6.0
galactokinase 6.0
uridine kinase 6.0
cyclohydrolase 5.9
deoxyribonuclease 5.8
xanthine oxidase 5.8
pantothenate kinase 5.8
xanthine dehydrogenase 5.8
AGT 5.7
CPL 5.7
ADH3 5.7
glyceraldehyde-3-phosphate dehydrogenase 5.6
alanine dehydrogenase 5.6
SpeB 5.6
dihydropyrimidinase 5.6
adenylate kinase 5.6
dihydroorotase 5.5
glyceraldehyde-3-phosphate dehydrogenase 5.4
glyceraldehyde-3-phosphate dehydrogenase 5.4
glyceraldehyde-3-phosphate dehydrogenase 5.4
alanine racemase 5.4
phosphoglycerate dehydrogenase 5.4
tryptophanyl-tRNA synthetase 5.4
more...
Compound
1-(3-pyridinyl)-2-butanone 13.7
6-Ethylmercaptopurine 13.7
C10H12N4O5S 12.7
C7H8N4S 11.7
Marmesin 11.7
Disperse Red 11 11.4
methoxyacetaldehyde 11.3
R 48 11.1
Marmesin 10.9
6-Mercaptopurine riboside 10.9
R 7000 10.7
1,8-Dinitropyrene 10.4
6-Methylpurine 10.4
Inosinic acid 10.4
6-Methylpurine 10.1
Ammonium metavanadate 10.1
Hypoxanthine 10.1
6-Thioguanine 10.0
Myosmine 9.8
N-Hydroxy-2-acetylaminofluorene 9.7
Orotidine 9.6
Prunetin 9.5
Cryptolepine 9.5
1,3-Butadiene 9.4
1,6-Dinitropyrene 9.4
PRPP 9.4
Tiazofurin 9.4
1,2-butanediol 9.3
XMP 9.2
ENNG 9.0
Aminoimidazole 8.9
1H-phenalen-1-one 8.8
IMP 8.7
Metanephrine 8.7
Bathocuproine 8.6
Lead nitrate 8.6
Xanthine 8.5
Formycin B 8.5
Formycin B 8.5
Purine 8.5
WR-1065 8.4
Glycidol 8.4
N-ethylurea 8.3
CI-921 8.3
dGDP 8.3
Normetanephrine 8.2
7H-dibenzo[c,g]carbazole 8.2
Diepoxybutane 8.1
isopropyl acetate 8.0
Neocarzinostatin 8.0
HNS 7.9
6-Mercaptopurine 7.9
Inosine 7.8
Kojic acid 7.8
Potassium bromate 7.7
2-ethylhexyl acrylate 7.7
5H-pyrido[4,3-b]indole 7.6
4-NQO 7.5
Phenolphthalein 7.5
Phenolphthalein 7.4
3-methoxybenzamide 7.4
XTP 7.4
Myrcene 7.3
Deoxyguanosine 7.3
TGR 7.3
methoxyacetic acid 7.3
Guanidinoacetic acid 7.2
Trifluorothymidine 7.2
1-methylhistidine 7.2
MMU 7.2
2-methoxyethanol 7.1
Propoxur 7.1
PhIP 7.1
dGTP 7.1
GMP 7.1
NaAsO2 7.1
O6-Methylguanine 7.1
5-methylchrysene 7.0
2-OHE1 7.0
Scopoletin 7.0
more...