Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P00492 (hypoxanthine-guanine phosphoribosyltransferase)
2,385 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein hypoxanthine-guanine phosphoribosyltransferase 2385 Mol 292 HPRT 253 Sep 189 AMP 158 X-linked 134 IMP 100 GMP 69 purine nucleoside phosphorylase 68 thymidine kinase 59 ATP 50 adenosine deaminase 50 GTP 44 glucose-6-phosphate dehydrogenase 40 phosphoglycerate kinase 40 fused 40 X-chromosome 39 adenosine kinase 37 xanthine oxidase 35 HAT 34 X-linked recessive 32 p53 31 hypoxanthine guanine phosphoribosyltransferase 29 housekeeping 29 hemoglobin 22 5'-nucleotidase 20 aprt 20 ATPase 18 lymphoid 15 glyceraldehyde-3-phosphate dehydrogenase 14 cytochrome P450 14 Gen 13 beta-actin 13 polypeptide 13 NAD 13 catalase 13 erythroid 12 promyelocytic leukemia 12 amidophosphoribosyltransferase 12 ADP 12 more...

Disease Lesch-Nyhan syndrome 636 cancer 226 carcinogenesis 116 tumor 95 hyperuricemia 93 gout 72 mental retardation 51 mental retardation 51 self-injurious behavior 43 lymphoma 40 leukemia 39 choreoathetosis 29 arthritis 28 enzyme deficiency 25 carcinoma 21 renal failure 20 neuroblastoma 18 xeroderma pigmentosum 18 anemia 17 nephrolithiasis 17 acute promyelocytic leukemia 16 acute lymphoblastic leukemia 15 immunodeficiency 15 Schistosoma mansoni 15 hepatocellular carcinoma 15 renal disease 14 genetic disorder 13 autism 13 cerebral palsy 13 herpes simplex 13 CEM 12 breast cancer 11 neurological disease 10 Epstein 10 tumorigenesis 9 MCL 9 mantle cell lymphoma 9 Down syndrome 9 malaria 9 fits 8 more...

Symptom spasticity 30 dystonia 18 starvation 7 pain 7 vomiting 6 athetosis 6 chorea 4 seizures 4 hypotonia 3 anesthesia 3 tremor 3 hypertonia 2 weakness 2 abdominal pain 2 renal colic 2 dysarthria 2 clumsiness 2 ataxia 2 dyspnea 1 overweight 1 labored breathing 1 dysesthesia 1 hepatomegaly 1 dysuria 1 forgetfulness 1 chromosome marker 1 muscle stiffness 1 splenomegaly 1 hyperoxia 1 myoclonus 1 colic 1 hemoptysis 1 nausea 1 Decreased activity 1 sleepiness 1 diarrhea 1 collapse 1 flank pain 1 respiratory distress 1 stridor 1 more...

Drug Mutagen 81 G418 16 BH4 13 lysine 10 Adenosine deaminase 9 caffeine 9 DNase I 7 Adriamycin 6 IFN-gamma 6 AZT 4 CSF 4 AZT 4 Acyclovir 3 -deoxyadenosine 3 Asn 3 Nephron 3 Thioguanine 3 ACT 3 THF 3 Etoposide 3 Dermatol 3 Rasburicase 2 NADH 2 Neocarzinostatin 2 ascorbate 2 ICI 2 AGG 2 nitroglycerin 2 TAT 2 vitamin E 2 IFN-beta 2 IL-2 2 Ethanol 2 Gel 2 Dial 1 Adozelesin 1 AraC 1 ETS 1 Formycin B 1 6-Methylpurine 1 more...

Enzyme hypoxanthine-guanine phosphoribosyltransferase 1475 adenine phosphoribosyltransferase 132 purine nucleoside phosphorylase 67 thymidine kinase 59 adenosine deaminase 52 adenosine deaminase 50 phosphoglycerate kinase 43 glucose-6-phosphate dehydrogenase 43 xanthine oxidase 34 adenosine kinase 32 IMP dehydrogenase 25 5'-nucleotidase 24 PRPP synthetase 21 glyceraldehyde-3-phosphate dehydrogenase 21 ATPase 19 xanthine phosphoribosyltransferase 17 reverse transcriptase 15 catalase 15 glyceraldehyde-3-phosphate dehydrogenase 15 glyceraldehyde-3-phosphate dehydrogenase 14 glyceraldehyde-3-phosphate dehydrogenase 14 glyceraldehyde-3-phosphate dehydrogenase 14 glutathione S-transferase 13 amidophosphoribosyltransferase 13 AMP deaminase 12 DNA polymerase 12 adenylosuccinate synthetase 12 superoxide dismutase 12 guanase 10 deaminase 10 alpha-galactosidase 10 endonuclease 10 orotate phosphoribosyltransferase 10 protein kinase 8 adenine deaminase 8 topoisomerase 8 topoisomerase 8 alkaline phosphatase 8 RNA polymerase 7 adenylate kinase 7 more...

Compound DNA 701 Dec 179 IMP 102 Clin 96 GMP 92 pyrene 60 pyrimidine 59 pyrimidine 59 phosphate 53 AMP 52 ATP 50 GTP 46 oxygen 40 sodium 37 Hypoxanthine 31 hydrogen 30 arginine 27 EMS 26 Purine 26 acetate 26 water 25 His 20 iron 19 lysine 18 methyl methanesulfonate 18 nitrogen 17 calcium 17 DMSO 15 sulfate 15 uridine 15 dGTP 14 creatinine 14 NAD 14 Guo 14 leucine 14 pyridine 14 anthracene 13 tryptophan 13 glucose 13 Asp 13 more...

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