Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P00492 (hypoxanthine-guanine phosphoribosyltransferase)
 2,385 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
hypoxanthine-guanine phosphoribosyltransferase 13.7
60S ribosomal protein L13 13.7
WEE1 homolog 13.7
TOP2 beta 12.4
60S ribosomal protein L32 12.1
Neurexophilin 1 11.7
Calsyntenin-3 11.7
MAE3 11.7
neurexophilin 3 11.7
Tp120 11.4
PPRibP 11.4
NPH2 11.4
engrailed homeobox 1 11.4
PRTFDC1 11.4
aprt 11.2
hypoxanthine guanine phosphoribosyltransferase 11.2
V3-3 11.1
Mvp1 11.1
neurexophilin 1 11.1
HPRT 11.0
more...
Disease
Deficiency of uracil phosphoribosyltransferase 13.7
Disorders of purine and pyrimidine metabolism 13.7
Hyperuricemic nephropathy 13.7
Lesch-Nyhan syndrome 13.3
Kelley-Seegmiller syndrome 13.1
UMP synthase deficiency 12.1
purine metabolism disorder 10.9
Marie's ataxia 10.1
glycinuria 9.7
APRT deficiency 9.7
gouty nephropathy 9.6
PNP deficiency 9.5
choreoathetosis 9.4
self-injurious behavior 9.2
uricosuria 8.4
adult soft tissue sarcoma 8.4
hyperuricemia 8.4
articulation disorder 8.2
self-destructive behavior 8.0
enzyme deficiency 7.9
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Symptom
athetosis 8.3
chromosome marker 6.6
labored breathing 6.0
spasticity 6.0
clumsiness 5.6
renal colic 5.0
dystonia 4.8
chorea 4.7
Decreased activity 4.6
Fluctuation 4.5
hypertonia 4.4
forgetfulness 4.3
dysesthesia 3.8
muscle stiffness 3.4
dysarthria 2.8
hypotonia 2.8
flank pain 2.6
stridor 2.5
dysuria 2.4
HSA 2.2
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Drug
6-Methylpurine 10.4
Thioguanine 10.2
2-Methoxyethanol 9.1
8-Azaguanine 9.0
Adozelesin 8.9
Formycin B 8.5
Mercaptopurine 8.3
Neocarzinostatin 7.9
Mutagen 7.5
Adenosine deaminase 7.5
TMX 7.4
Rasburicase 7.3
BH4 6.8
Deoxyadenosine 6.8
Rasburicase 6.7
G418 6.6
Febuxostat 6.5
Adderall 6.4
Cytidine 5.8
Propidium 5.7
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Enzyme
hypoxanthine-guanine phosphoribosyltransferase 12.9
xanthine phosphoribosyltransferase 11.6
formyltetrahydrofolate deformylase 11.4
adenine phosphoribosyltransferase 11.3
amidophosphoribosyltransferase 10.5
PRPP synthetase 10.2
adenine deaminase 10.0
acyl-CoA:malonyl-CoA C-acyltransferase 10.0
3-methyladenine DNA glycosylase I 9.6
adenylosuccinate synthetase 9.6
purine nucleoside phosphorylase 9.3
deoxyadenosine kinase 9.3
guanase 9.2
EC 1.3.2.3 9.1
nicotinic acid phosphoribosyltransferase 9.1
adenylosuccinate lyase 9.0
GMP reductase 8.9
AICAR transformylase 8.9
adenosine kinase 8.8
orotate phosphoribosyltransferase 8.6
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Compound
1-(3-pyridinyl)-2-butanone 13.7
6-Ethylmercaptopurine 13.7
C10H12N4O5S 12.7
Marmesin 11.7
C7H8N4S 11.7
Disperse Red 11 11.4
methoxyacetaldehyde 11.3
R 48 11.1
6-Mercaptopurine riboside 10.9
Marmesin 10.9
R 7000 10.7
1,8-Dinitropyrene 10.4
6-Methylpurine 10.4
Inosinic acid 10.4
Ammonium metavanadate 10.1
6-Methylpurine 10.1
Hypoxanthine 10.1
6-Thioguanine 10.0
Myosmine 9.8
N-Hydroxy-2-acetylaminofluorene 9.7
more...