Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P00492 (hypoxanthine-guanine phosphoribosyltransferase)
2,385 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
hypoxanthine-guanine phosphoribosyltransferase 2385
Mol 292
HPRT 253
Sep 189
AMP 158
X-linked 134
IMP 100
GMP 69
purine nucleoside phosphorylase 68
thymidine kinase 59
ATP 50
adenosine deaminase 50
GTP 44
fused 40
glucose-6-phosphate dehydrogenase 40
phosphoglycerate kinase 40
X-chromosome 39
adenosine kinase 37
xanthine oxidase 35
HAT 34
more...
Disease
Lesch-Nyhan syndrome 636
cancer 226
carcinogenesis 116
tumor 95
hyperuricemia 93
gout 72
mental retardation 51
mental retardation 51
self-injurious behavior 43
lymphoma 40
leukemia 39
choreoathetosis 29
arthritis 28
enzyme deficiency 25
carcinoma 21
renal failure 20
xeroderma pigmentosum 18
neuroblastoma 18
nephrolithiasis 17
anemia 17
more...
Symptom
spasticity 30
dystonia 18
pain 7
starvation 7
athetosis 6
vomiting 6
seizures 4
chorea 4
anesthesia 3
hypotonia 3
tremor 3
hypertonia 2
ataxia 2
abdominal pain 2
renal colic 2
dysarthria 2
weakness 2
clumsiness 2
hyperoxia 1
myoclonus 1
more...
Drug
Mutagen 81
G418 16
BH4 13
lysine 10
Adenosine deaminase 9
caffeine 9
DNase I 7
Adriamycin 6
IFN-gamma 6
CSF 4
AZT 4
AZT 4
Acyclovir 3
Etoposide 3
Dermatol 3
Thioguanine 3
ACT 3
-deoxyadenosine 3
Nephron 3
THF 3
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase 1475
adenine phosphoribosyltransferase 132
purine nucleoside phosphorylase 67
thymidine kinase 59
adenosine deaminase 52
adenosine deaminase 50
phosphoglycerate kinase 43
glucose-6-phosphate dehydrogenase 43
xanthine oxidase 34
adenosine kinase 32
IMP dehydrogenase 25
5'-nucleotidase 24
glyceraldehyde-3-phosphate dehydrogenase 21
PRPP synthetase 21
ATPase 19
xanthine phosphoribosyltransferase 17
glyceraldehyde-3-phosphate dehydrogenase 15
catalase 15
reverse transcriptase 15
glyceraldehyde-3-phosphate dehydrogenase 14
more...
Compound
DNA 701
Dec 179
IMP 102
Clin 96
GMP 92
pyrene 60
pyrimidine 59
pyrimidine 59
phosphate 53
AMP 52
ATP 50
GTP 46
oxygen 40
sodium 37
Hypoxanthine 31
hydrogen 30
arginine 27
Purine 26
EMS 26
acetate 26
more...