Gene/Protein
Disease
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Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
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Drug
Enzyme
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Target Concepts:
Gene/Protein
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Query: UNIPROT:P00492 (
hypoxanthine-guanine phosphoribosyltransferase
)
2,385
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Aberrations of the long arm of chromosome 5 (5q) were studied in 79 clear cell renal carcinomas (clear cell RCC) by LOH (loss of heterozygosity) method, using microsatellite markers D5S107, CRTL1,
LNS
-CA,
IL-9
.RP1, CFS1R and GeneScan analysis software. Alterations of chromosome 5q were detected in 42% of cases. We found, that accumulation of genomic abnormalities at multiple loci of 5q, especially in 5q21-qter region, where genes for cytokines are located, correlates with morphologic features of better prognosis.
...
PMID:Abnormalities of chromosome 5q correlate with morphologic features of better prognosis in clear cell renal carcinomas. 749 35
