Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P00492 (
hypoxanthine-guanine phosphoribosyltransferase
)
2,385
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
5-Hydroxytryptophan
(
5-HTP
) treatment of a single case of
Lesch-Nyhan syndrome
showing compulsive self-mutilation, athetoid movements, and characteristic clinical biochemical picture was studied on a double-blind basis.
5-HTP
or placebo was administered for seven fortnightly treatment blocks.
5-HTP
produced a significant reduction of athetoid movement and a sedative effect but did not improve the patient's mood or reduce self-mutilation.
...
PMID:Double-blind clinical trial of 5-hydroxytryptophan in a case of Lesch-Nyhan syndrome. 79 98
