Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P00492 (
hypoxanthine-guanine phosphoribosyltransferase
)
2,385
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Fullerene and their derivatives have many potential new applications. However, there is increasing concern regarding toxicity as very little information is available about fullerene derivatives--protein interactions. In the present work, to identify proteins interacting with chiral fullerene derivatives, Potential Drug Target Database was searched using reverse docking approach.
Hypoxanthine phosphoribosyltransferase
and
Beta-secretase
-1 were found to be the most favorable protein targets for fullerene derivatives.
...
PMID:In silico approaches: prediction of biological targets for fullerene derivatives. 2148 19
