Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:O76050 (neu)
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Human Gene/Protein
neu 13.0
h-neu 13.0
hypothetical protein H41 13.0
quiescin Q6 sulfhydryl oxidase 1 12.0
TMEM10 12.0
KIAA0554 12.0
Neur2 11.4
KIAA1543 11.4
p185 11.3
NANOG2 11.0
p50E4F 11.0
C-abl 11.0
amplified in osteosarcoma 11.0
C10orf90 11.0
NEURL4 10.9
Tieg3 10.6
PNCK 10.6
neuroepithelial cell transforming gene 1 10.6
PPIL3 10.4
TIP120B 10.3
Opalin 10.3
NRG-4 10.2
RUVBL 10.2
TOP2A protein 10.0
CGR19 10.0
RNF26 10.0
HER2 10.0
MAK-V 9.9
STARD10 9.8
C10orf99 9.8
ERRB2 9.8
PFDN4 9.8
Noelin 9.8
EAPP 9.6
NACB 9.6
AP-2B 9.6
MAGE2 9.6
erbB-2 9.6
DMXL2 9.5
ACEH 9.5
HER4 9.4
retinoic acid receptor, alpha 9.4
hDMP1 9.4
erbB-3 9.3
open reading frame X 9.3
RASSF3 9.3
H-2RIIBP 9.3
TPBG 9.3
Br3 9.2
LEF1 protein 9.2
NEU 9.1
CEACAM1 protein 9.1
GlcNAc-T V 9.1
SEREX-defined 9.1
amplified in breast cancer 1 9.0
FXYD3 9.0
c-erbB-3 9.0
ErbB-3 9.0
PLU-1 8.9
T-cell lymphoma invasion and metastasis 1 8.9
MCT 1 8.9
Reversion-inducing cysteine-rich protein with Kazal motifs 8.9
metastasis associated protein 8.8
tumor-related protein 8.7
putative zinc finger transcription factor 8.7
SEI-1 8.7
lipophilin B 8.7
MSH6 protein 8.7
E4TF1 8.6
TIEG2 8.6
seven transmembrane domain protein 8.6
CISH 8.6
RASSF4 8.6
ASGR1 8.6
HER3 8.6
GRB7 8.6
B3GNT2 8.5
WD repeat domain 5 8.5
NOTCH1 protein 8.5
ER81 8.5
more...
Disease
MLVI2 13.0
Bowen's disease, pagetoid 13.0
Metaplastic Breast Carcinoma 11.4
Infiltrating duct carcinoma 11.0
DIN 2 10.6
Follicular neoplasms 10.2
Secretory carcinoma of the breast 9.5
DYT2 9.3
Stromal sarcoma 9.3
Small cell osteosarcoma 9.0
Nevus sebaceus of Jadassohn 9.0
Paget's disease of the breast 8.9
Squamous cell carcinoma in situ 8.9
Scrotum 8.9
Scrotum 8.6
Cylindroma 8.6
Sialoblastoma 8.5
Squamous cell carcinoma in situ 8.5
stage IV renal cell carcinoma 8.5
Salivary duct carcinoma 8.4
Mononeuritis multiplex 8.2
Clear cell meningioma 8.2
salivary gland adenocarcinoma 8.2
Extramammary Paget's disease 8.1
Breast carcinoma 8.0
testicular yolk sac tumor 8.0
Psammoma 7.9
metaplastic carcinoma 7.9
stage III breast cancer 7.8
ductal carcinoma 7.8
Vagina 7.7
mammary tumor 7.7
EIC 7.7
Parosteal osteosarcoma 7.6
comedo 7.6
LCIS 7.6
inflammatory breast cancer 7.6
Serous carcinoma 7.5
Paget's disease of the nipple 7.5
ductal carcinoma in situ 7.5
infiltrating ductal carcinoma 7.4
preneoplastic state 7.4
Vagina 7.4
ovarian endometrioid adenocarcinoma 7.3
Hers 7.3
metastatic endometrial cancer 7.3
bilateral cancer 7.3
adenocarcinoma of unknown primary 7.2
metastatic breast cancer 7.2
breast cancer stage 7.1
androgen independent prostate cancer 7.1
RCA1 7.0
lobular carcinoma in situ 7.0
carcinoma of unknown origin 6.8
bone marrow metastases 6.8
Epithelial hyperplasia 6.8
Myoepithelial carcinoma 6.7
WSS 6.7
cholangioma 6.7
Pelizaeus-Merzbacher 6.6
lobular breast carcinoma 6.6
Lymph node metastases 6.6
stage I breast cancer 6.6
Undifferentiated carcinoma 6.6
stage IIIA NSCLC 6.6
Vesicular stomatitis 6.6
GFD 6.6
Metastatic colorectal cancer 6.5
carcinoma of the parotid 6.5
iris melanoma 6.5
carcinoma of the breast 6.5
Paraneoplastic cerebellar degeneration 6.5
large cell carcinomas 6.5
Luminal 6.4
bilateral breast cancer 6.4
Extraskeletal osteosarcoma 6.4
carcinoma of the breast 6.4
Marcus Gunn 6.3
Sebaceous carcinoma 6.3
fibrocystic breast disease 6.3
more...
Symptom
retracted nipple 11.4
Sore 8.2
breast hyperplasia 7.8
nipple discharge 6.8
Sister Mary Joseph's nodule 6.7
nipple discharge 6.7
peau d'orange 6.5
female puberty 6.1
rigors 4.3
Spots 4.1
hot flashes 2.9
decreased appetite 2.8
hot flushes 2.7
menopausal symptoms 2.3
heartburn 1.9
chills 1.9
masculinization 1.6
asthenia 1.6
cancer pain 1.4
bone pain 1.4
erythema 1.3
nausea 1.3
anorexia 0.8
hepatomegaly 0.5
paresis 0.5
back pain 0.4
vomiting 0.3
sleepiness 0.3
spasticity 0.3
arthralgia 0.2
starvation -0.1
overweight -0.1
syncope -0.2
dyspnea -0.2
nausea and vomiting -0.3
low back pain -0.3
constipation -0.4
abdominal pain -0.4
Ill -0.5
thinning -0.5
diarrhea -0.5
cough -0.6
fatigue -0.7
stigma -0.7
functional recovery -0.7
exhaustion -0.8
pain -0.9
acidity -0.9
ataxia -1.0
Welt -1.0
headache -1.2
anesthesia -1.5
seizures -1.7
analgesia -1.8
Drug
Cetraxate hydrochloride 10.0
Herceptin 9.7
Halcinonide 9.3
Pertuzumab 8.9
Alimta 8.2
Tykerb 8.2
Taxotere 7.4
Tarceva 7.2
Epidoxorubicin 7.2
Provenge 7.2
Navelbine 7.0
OctreoScan 7.0
CDX 7.0
Radicicol 6.9
Tipifarnib 6.8
Xeloda 6.7
CDX 6.5
Insulin detemir 6.5
Gefitinib 6.4
Gemzar 6.4
Vinorelbine 6.2
Resovist 6.2
anti-CD33 6.2
Fulvestrant 6.1
Emodin 6.1
Axitinib 5.9
Pemetrexed 5.9
Docetaxel 5.9
Cetuximab 5.9
Emodin 5.8
Arimidex 5.8
Clobetasol propionate 5.7
Paraffin 5.6
Bexarotene 5.5
Daclizumab 5.4
Erlotinib 5.4
Olive oil 5.3
Parlodel 5.2
Taxol 5.1
Spiegel 5.1
FCV 5.1
ETS 4.9
Abciximab 4.7
DM1 4.7
Colombo 4.6
DEL 4.6
Everolimus 4.5
Tocopherol 4.5
uPA 4.5
Bevacizumab 4.5
Vorinostat 4.5
Gleevec 4.5
Ipilimumab 4.3
MDM 4.3
Valsartan 4.1
Rituximab 4.1
KGF 4.1
IFN-gamma 4.0
GEO 3.9
AIC 3.9
Imiquimod 3.9
Adalimumab 3.9
CED 3.8
Norplant 3.8
RFP 3.7
Imatinib 3.7
R1881 3.7
CPT-11 3.7
PDL 3.6
EPI 3.5
CAM 3.5
PMEA 3.4
G418 3.4
TAC 3.3
Irinotecan 3.3
MAP 3.3
CSF 3.2
Gastro 3.1
DEX 3.1
Oxaliplatin 3.1
more...
Enzyme
ERK 7.1
bleomycin hydrolase 6.6
ceramide kinase 6.2
alpha-methylacyl-CoA racemase 6.1
N-acetylglucosaminyltransferase V 5.7
GD3 synthase 5.4
homogentisate 1,2-dioxygenase 5.4
PFI 5.4
PTPase 5.3
cathepsin D 5.3
beta-1,4-galactosyltransferase 5.2
dihydrodiol dehydrogenase 5.2
phosphatidylinositol 4-kinase 5.1
endo-N 5.1
lysyl oxidase 5.0
thymidine phosphorylase 5.0
farnesyltransferase 4.9
dihydropyrimidine dehydrogenase 4.9
iodothyronine 5'-deiodinase 4.8
VOR 4.6
matriptase 4.4
CEP 4.4
farnesyltransferase 4.4
FAST 4.4
topoisomerase 4.4
caspase-2 4.4
prostate-specific antigen 4.4
legumain 4.4
topoisomerase 4.3
caspase-2 4.3
dihydropyrimidine dehydrogenase 4.3
PHD 4.2
CGT 4.2
ALDH 4.2
STK11 4.1
caspase-6 4.1
caspase-6 4.0
matriptase 4.0
sialidase 3.9
IKK 3.9
CEP 3.9
chloramphenicol acetyltransferase 3.8
prostaglandin synthetase 3.7
MDR 3.7
porphobilinogen deaminase 3.7
ricin 3.6
dihydrofolate reductase 3.6
methylenetetrahydrofolate reductase 3.5
methylenetetrahydrofolate reductase 3.5
PARP 3.5
thymidylate synthase 3.5
insulin-degrading enzyme 3.4
phosphatidylinositol 3-kinase 3.4
cytosine deaminase 3.4
CD10 3.4
SST 3.4
urokinase-type plasminogen activator 3.4
PNGase F 3.4
ubiquitin-protein ligase 3.3
granzyme B 3.3
BAT 3.3
GRK2 3.2
AMPK 3.2
Pla 3.1
histone demethylase 3.1
mitogen-activated protein kinase 3.1
chondroitinase 3.0
cdc2 2.9
lysin 2.9
thymidine kinase 2.9
chondroitinase 2.9
aldehyde dehydrogenase 2.9
aldehyde dehydrogenase 2.9
aldehyde dehydrogenase 2.9
ADH 2.8
3-hydroxy-3-methylglutaryl-CoA reductase 2.8
matrix metalloproteinase 2 2.8
15-lipoxygenase 2.8
N-acetyltransferase 2.8
TAT 2.7
more...
Compound
LG 100268 11.0
p-Cresidine 9.8
DABI 9.6
4-ethoxyphenol 9.5
NEU 9.1
3-HP 8.4
Solamargine 8.2
Acar 8.1
N-ethylurea 7.6
Nitroxoline 7.5
ENU 7.3
Proflavine 7.2
FANFT 7.2
EGT 7.1
Toremifene 7.0
Garcinol 6.9
W37 6.8
Vidarabine 6.8
Tangeretin 6.8
IDC 6.7
1H-pyrrole-2,5-dione 6.6
Benzyl isothiocyanate 6.4
Epirubicin 6.3
arsenic acid 6.3
arsenic acid 6.3
arsenic acid 6.3
OLN 6.3
arsenic acid 6.3
BDH 6.2
ONT 6.2
Phenethyl isothiocyanate 6.1
TIF 6.1
Emodin 6.1
Phosphoserine 6.0
Mangostin 6.0
N-(4-hydroxyphenyl)retinamide 6.0
Geldanamycin 6.0
Capecitabine 5.9
MBT 5.9
C 5 5.9
DFS 5.8
DOPE 5.7
1,4,8,11-tetraazacyclotetradecane 5.7
EOC 5.6
Paraformaldehyde 5.6
Temsirolimus 5.6
Withaferin A 5.5
Luminal 5.3
ASE 5.3
Lentinan 5.3
Paraformaldehyde 5.3
DMC 5.3
1,4,7,10-tetraazacyclododecane 5.2
F23 5.2
Plumbagin 5.1
DMPC 5.1
(-)-Epigallocatechin 5.1
Paclitaxel 5.1
Ara-A 5.1
ASN 4.9
MDA 4.9
MNU 4.9
Rhein 4.9
Emodin 4.9
Gemcitabine 4.9
Gemcitabine 4.9
Lip 4.8
DMB 4.8
Carcinogen 4.8
Alba 4.6
Fluvastatin 4.6
MNU 4.6
PBD 4.6
TAA 4.6
Phalloidin 4.6
Eosin 4.6
DMB 4.5
quinazoline 4.5
quinazoline 4.4
Dieldrin 4.4
more...