Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:O76050 (
neu
)
3,969
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
neu
3969
HER2
1571
erbB-2
497
epidermal growth factor receptor
485
estrogen receptor
346
p53
336
progesterone receptor
315
Sep
274
Mol
261
tyrosine kinase
243
EGFR
162
proto-oncogene
158
p185
151
ras
145
epidermal growth factor
144
c-myc
116
CD8
115
Ki-67
115
EGF receptor
105
cytokine
94
receptor tyrosine kinase
92
hormone receptor
90
EGF
86
CD4
77
neuregulin
68
ERBB2
64
E-cadherin
63
nodal
63
fused
59
IFN-gamma
57
cyclin D1
57
BRCA1
54
cytokeratin
53
AKT
51
Bcl-2
47
p21
46
She
44
bcl-2
44
glycoprotein
43
IFN
43
androgen receptor
43
PTEN
41
vascular endothelial growth factor
41
HLA
41
HLA-A2
40
MAPK
40
CEA
39
MUC1
39
aromatase
38
tumor-associated antigen
38
tyrosine kinase receptor
38
p63
37
H-ras
37
p27
36
HER3
36
PI3K
36
FISH
35
insulin
35
K-ras
35
CK5
35
ATP
34
carcinoembryonic antigen
33
GM-CSF
32
interferon
31
p16
31
IL-2
30
scFv
30
polypeptide
29
mTOR
28
HER4
28
vimentin
28
cage
27
CK7
26
MRI
26
c-kit
26
MIB
25
c-fos
25
MHC class I
25
caspase-3
24
TNF
24
more...
Disease
tumor
1830
cancer
1552
breast cancer
1547
carcinoma
537
metastases
257
tumor growth
207
tumorigenesis
205
carcinogenesis
189
mammary tumor
172
metastatic breast cancer
139
adenocarcinoma
138
ovarian cancer
110
MCF
108
tumor progression
104
ductal carcinoma
102
ductal carcinoma in situ
84
primary tumor
67
lung cancer
58
melanoma
54
prostate cancer
53
squamous cell carcinoma
48
epithelial ovarian cancer
47
gastric cancer
47
non-small cell lung cancer
37
colorectal cancer
36
endometrial cancer
33
carcinoma of the breast
31
aggressiveness
30
leukemia
27
aggression
27
lung carcinoma
27
retinoblastoma
25
lung metastases
23
carcinoma of the breast
22
bladder cancer
22
hepatocellular carcinoma
21
lymphoma
21
dysplasia
20
renal cell carcinoma
20
Luminal
19
neuroblastoma
19
glioblastoma
19
glioma
19
pancreatic cancer
19
colon cancer
18
infiltrating ductal carcinoma
17
invasive cancer
17
osteosarcoma
16
inflammatory breast cancer
16
SDS
16
carcinoma in situ
15
residual disease
15
brain metastases
15
sarcoma
15
neoplastic transformation
14
chronic myeloid leukemia
14
EMA
14
PDB
14
Barrett's esophagus
13
infectious diseases
13
SCID
13
tumor angiogenesis
13
comedo
13
WT1
13
cold
12
obesity
12
diabetes
12
schwannoma
12
liver metastases
12
Breast carcinoma
11
PSA
11
multiple myeloma
11
Blocking
10
bone metastases
9
glioblastoma multiforme
9
adenoma
9
carcinosarcoma
9
depression
9
tumor initiation
9
lymphadenopathy
8
more...
Symptom
pain
18
nipple discharge
7
nausea
7
nipple discharge
7
vomiting
5
anesthesia
5
diarrhea
5
fatigue
4
erythema
4
dyspnea
3
starvation
3
overweight
3
seizures
3
anorexia
3
headache
3
abdominal pain
3
back pain
2
rigors
2
cough
2
sleepiness
2
chills
2
Welt
1
acidity
1
constipation
1
retracted nipple
1
heartburn
1
bone pain
1
menopausal symptoms
1
Sister Mary Joseph's nodule
1
female puberty
1
breast hyperplasia
1
Sore
1
low back pain
1
hepatomegaly
1
syncope
1
masculinization
1
peau d'orange
1
Ill
1
analgesia
1
cancer pain
1
paresis
1
thinning
1
Spots
1
functional recovery
1
asthenia
1
decreased appetite
1
hot flushes
1
arthralgia
1
stigma
1
exhaustion
1
spasticity
1
hot flashes
1
ataxia
1
nausea and vomiting
1
Drug
Herceptin
235
IFN-gamma
57
CSF
36
IL-2
30
MAP
19
lysine
17
Taxol
14
Dermatol
14
Docetaxel
13
Paraffin
13
Taxotere
13
Gefitinib
13
ETS
10
Pertuzumab
8
CAM
8
Cetuximab
7
CTX
6
vitamin E
6
Rituximab
6
uPA
6
DM1
5
Cardiovasc
5
Adriamycin
5
Bevacizumab
5
ICI
4
Tarceva
4
ABC
4
ROS
4
Erlotinib
4
CDX
4
Gleevec
4
CDX
4
Emodin
4
Imatinib
4
Vinorelbine
4
Emodin
4
CPT-11
3
Navelbine
3
anti-CD33
3
Fluorescein
3
p75
3
Pemetrexed
3
Retinoic acid
3
EPI
3
Alimta
3
GEO
3
Norplant
3
Fulvestrant
3
G418
3
TAT
2
Tykerb
2
ROC
2
Gemzar
2
Olive oil
2
TAC
2
ENT
2
Everolimus
2
Vitamin E
2
G-CSF
2
Kenyan
2
EE2
2
Tocopherol
2
Gel
2
Xeloda
2
Mutagen
2
RFP
2
DNase I
2
BH4
1
Resovist
1
Dial
1
Halcinonide
1
Spiegel
1
Parlodel
1
Sorafenib
1
CTC
1
Spectrum
1
DHT
1
Ipilimumab
1
balanced salt solution
1
Radicicol
1
more...
Enzyme
ERK
1665
mitogen-activated protein kinase
101
protein kinase
43
focal adhesion kinase
27
topoisomerase
25
topoisomerase
24
cathepsin D
20
caspase-3
19
PARP
19
prostate-specific antigen
18
luciferase
17
protein kinase C
17
phosphatidylinositol 3-kinase
15
MEK
14
urokinase-type plasminogen activator
14
CD10
13
reverse transcriptase
13
proteasome
12
P-glycoprotein
11
peroxidase
10
IKK
9
chloramphenicol acetyltransferase
9
dihydrofolate reductase
9
neuraminidase
9
phospholipase C
9
AMP-activated protein kinase
8
catalase
8
cdc2
8
AMPK
7
alkaline phosphatase
7
APC
7
AMPK
7
MDR
7
thymidine kinase
7
RNA polymerase
6
RNase
6
RNase
6
MAP
6
beta-galactosidase
6
caspase-9
5
PTPase
5
aldehyde dehydrogenase
5
glutathione S-transferase
5
thymidylate synthase
5
sialidase
5
tyrosinase
5
calcineurin
5
ricin
5
lysyl oxidase
5
farnesyltransferase
4
farnesyltransferase
4
granzyme B
4
aldehyde dehydrogenase
4
aldehyde dehydrogenase
4
aldehyde dehydrogenase
4
thrombin
4
ACS
4
NOS
4
aldehyde dehydrogenase
4
thymidine phosphorylase
4
ATPase
4
caspase-8
3
dihydropyrimidine dehydrogenase
3
transcriptase
3
MMP
3
methylenetetrahydrofolate reductase
3
ribonuclease
3
methylenetetrahydrofolate reductase
3
ribonuclease
3
collagenase
3
aspartate aminotransferase
3
prostaglandin synthetase
3
dihydropyrimidine dehydrogenase
3
NQO1
3
ornithine decarboxylase
3
acid phosphatase
3
DNase
3
phosphatidylinositol 4-kinase
3
MMP-3
2
PHD
2
more...
Compound
DNA
429
Dec
315
tyrosine
225
Clin
200
MDA
92
ATP
34
serine
28
cysteine
25
valine
25
TNF
24
iron
23
glutamic acid
23
water
23
threonine
23
phosphate
22
lysine
21
retinoic acid
21
calcium
21
PEG
19
Luminal
19
TNM
19
SDS
18
CAM
17
cAMP
16
oxygen
16
Estrogen
15
ENU
15
acetate
15
Estrogen
15
galactose
15
glucose
15
DBA
14
methionine
14
anthracene
13
formaldehyde
13
barium
13
Progesterone
13
arginine
12
PEG
12
Paclitaxel
12
MTT
12
sodium
12
tryptophan
11
Pac
11
NEU
11
alanine
10
silver
10
hydrogen
10
leucine
10
Asp
9
MAP
9
Tamoxifen
9
DFS
9
Tamoxifen
9
Ile
9
CAP
9
CAP
8
Adriamycin
8
Phe
8
Curcumin
8
sulfate
8
zinc
7
PMA
7
iodine
7
vitamin D
7
His
7
MDR
7
DSM
7
VP-16
6
CTX
6
COS
6
ethanol
6
proline
6
CAT
6
CAT
6
NH2
6
DTPA
6
BCR
6
potassium
6
MEK
6
more...