Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:O76050 (neu)
3,969 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
neu 3969
HER2 1571
erbB-2 497
epidermal growth factor receptor 485
estrogen receptor 346
p53 336
progesterone receptor 315
Sep 274
Mol 261
tyrosine kinase 243
EGFR 162
proto-oncogene 158
p185 151
ras 145
epidermal growth factor 144
c-myc 116
CD8 115
Ki-67 115
EGF receptor 105
cytokine 94
receptor tyrosine kinase 92
hormone receptor 90
EGF 86
CD4 77
neuregulin 68
ERBB2 64
E-cadherin 63
nodal 63
fused 59
IFN-gamma 57
cyclin D1 57
BRCA1 54
cytokeratin 53
AKT 51
Bcl-2 47
p21 46
She 44
bcl-2 44
glycoprotein 43
IFN 43
androgen receptor 43
PTEN 41
vascular endothelial growth factor 41
HLA 41
HLA-A2 40
MAPK 40
CEA 39
MUC1 39
aromatase 38
tumor-associated antigen 38
tyrosine kinase receptor 38
p63 37
H-ras 37
p27 36
HER3 36
PI3K 36
FISH 35
insulin 35
K-ras 35
CK5 35
ATP 34
carcinoembryonic antigen 33
GM-CSF 32
interferon 31
p16 31
IL-2 30
scFv 30
polypeptide 29
mTOR 28
HER4 28
vimentin 28
cage 27
CK7 26
MRI 26
c-kit 26
MIB 25
c-fos 25
MHC class I 25
caspase-3 24
TNF 24
more...
Disease
tumor 1830
cancer 1552
breast cancer 1547
carcinoma 537
metastases 257
tumor growth 207
tumorigenesis 205
carcinogenesis 189
mammary tumor 172
metastatic breast cancer 139
adenocarcinoma 138
ovarian cancer 110
MCF 108
tumor progression 104
ductal carcinoma 102
ductal carcinoma in situ 84
primary tumor 67
lung cancer 58
melanoma 54
prostate cancer 53
squamous cell carcinoma 48
epithelial ovarian cancer 47
gastric cancer 47
non-small cell lung cancer 37
colorectal cancer 36
endometrial cancer 33
carcinoma of the breast 31
aggressiveness 30
leukemia 27
aggression 27
lung carcinoma 27
retinoblastoma 25
lung metastases 23
carcinoma of the breast 22
bladder cancer 22
hepatocellular carcinoma 21
lymphoma 21
dysplasia 20
renal cell carcinoma 20
Luminal 19
neuroblastoma 19
glioblastoma 19
glioma 19
pancreatic cancer 19
colon cancer 18
infiltrating ductal carcinoma 17
invasive cancer 17
osteosarcoma 16
inflammatory breast cancer 16
SDS 16
carcinoma in situ 15
residual disease 15
brain metastases 15
sarcoma 15
neoplastic transformation 14
chronic myeloid leukemia 14
EMA 14
PDB 14
Barrett's esophagus 13
infectious diseases 13
SCID 13
tumor angiogenesis 13
comedo 13
WT1 13
cold 12
obesity 12
diabetes 12
schwannoma 12
liver metastases 12
Breast carcinoma 11
PSA 11
multiple myeloma 11
Blocking 10
bone metastases 9
glioblastoma multiforme 9
adenoma 9
carcinosarcoma 9
depression 9
tumor initiation 9
lymphadenopathy 8
more...
Symptom
pain 18
nipple discharge 7
nausea 7
nipple discharge 7
vomiting 5
anesthesia 5
diarrhea 5
fatigue 4
erythema 4
dyspnea 3
starvation 3
overweight 3
seizures 3
anorexia 3
headache 3
abdominal pain 3
back pain 2
rigors 2
cough 2
sleepiness 2
chills 2
Welt 1
acidity 1
constipation 1
retracted nipple 1
heartburn 1
bone pain 1
menopausal symptoms 1
Sister Mary Joseph's nodule 1
female puberty 1
breast hyperplasia 1
Sore 1
low back pain 1
hepatomegaly 1
syncope 1
masculinization 1
peau d'orange 1
Ill 1
analgesia 1
cancer pain 1
paresis 1
thinning 1
Spots 1
functional recovery 1
asthenia 1
decreased appetite 1
hot flushes 1
arthralgia 1
stigma 1
exhaustion 1
spasticity 1
hot flashes 1
ataxia 1
nausea and vomiting 1
Drug
Herceptin 235
IFN-gamma 57
CSF 36
IL-2 30
MAP 19
lysine 17
Taxol 14
Dermatol 14
Docetaxel 13
Paraffin 13
Taxotere 13
Gefitinib 13
ETS 10
Pertuzumab 8
CAM 8
Cetuximab 7
CTX 6
vitamin E 6
Rituximab 6
uPA 6
DM1 5
Cardiovasc 5
Adriamycin 5
Bevacizumab 5
ICI 4
Tarceva 4
ABC 4
ROS 4
Erlotinib 4
CDX 4
Gleevec 4
CDX 4
Emodin 4
Imatinib 4
Vinorelbine 4
Emodin 4
CPT-11 3
Navelbine 3
anti-CD33 3
Fluorescein 3
p75 3
Pemetrexed 3
Retinoic acid 3
EPI 3
Alimta 3
GEO 3
Norplant 3
Fulvestrant 3
G418 3
TAT 2
Tykerb 2
ROC 2
Gemzar 2
Olive oil 2
TAC 2
ENT 2
Everolimus 2
Vitamin E 2
G-CSF 2
Kenyan 2
EE2 2
Tocopherol 2
Gel 2
Xeloda 2
Mutagen 2
RFP 2
DNase I 2
BH4 1
Resovist 1
Dial 1
Halcinonide 1
Spiegel 1
Parlodel 1
Sorafenib 1
CTC 1
Spectrum 1
DHT 1
Ipilimumab 1
balanced salt solution 1
Radicicol 1
more...
Enzyme
ERK 1665
mitogen-activated protein kinase 101
protein kinase 43
focal adhesion kinase 27
topoisomerase 25
topoisomerase 24
cathepsin D 20
caspase-3 19
PARP 19
prostate-specific antigen 18
luciferase 17
protein kinase C 17
phosphatidylinositol 3-kinase 15
MEK 14
urokinase-type plasminogen activator 14
CD10 13
reverse transcriptase 13
proteasome 12
P-glycoprotein 11
peroxidase 10
IKK 9
chloramphenicol acetyltransferase 9
dihydrofolate reductase 9
neuraminidase 9
phospholipase C 9
AMP-activated protein kinase 8
catalase 8
cdc2 8
AMPK 7
alkaline phosphatase 7
APC 7
AMPK 7
MDR 7
thymidine kinase 7
RNA polymerase 6
RNase 6
RNase 6
MAP 6
beta-galactosidase 6
caspase-9 5
PTPase 5
aldehyde dehydrogenase 5
glutathione S-transferase 5
thymidylate synthase 5
sialidase 5
tyrosinase 5
calcineurin 5
ricin 5
lysyl oxidase 5
farnesyltransferase 4
farnesyltransferase 4
granzyme B 4
aldehyde dehydrogenase 4
aldehyde dehydrogenase 4
aldehyde dehydrogenase 4
thrombin 4
ACS 4
NOS 4
aldehyde dehydrogenase 4
thymidine phosphorylase 4
ATPase 4
caspase-8 3
dihydropyrimidine dehydrogenase 3
transcriptase 3
MMP 3
methylenetetrahydrofolate reductase 3
ribonuclease 3
methylenetetrahydrofolate reductase 3
ribonuclease 3
collagenase 3
aspartate aminotransferase 3
prostaglandin synthetase 3
dihydropyrimidine dehydrogenase 3
NQO1 3
ornithine decarboxylase 3
acid phosphatase 3
DNase 3
phosphatidylinositol 4-kinase 3
MMP-3 2
PHD 2
more...
Compound
DNA 429
Dec 315
tyrosine 225
Clin 200
MDA 92
ATP 34
serine 28
cysteine 25
valine 25
TNF 24
iron 23
glutamic acid 23
water 23
threonine 23
phosphate 22
lysine 21
retinoic acid 21
calcium 21
PEG 19
Luminal 19
TNM 19
SDS 18
CAM 17
cAMP 16
oxygen 16
Estrogen 15
ENU 15
acetate 15
Estrogen 15
galactose 15
glucose 15
DBA 14
methionine 14
anthracene 13
formaldehyde 13
barium 13
Progesterone 13
arginine 12
PEG 12
Paclitaxel 12
MTT 12
sodium 12
tryptophan 11
Pac 11
NEU 11
alanine 10
silver 10
hydrogen 10
leucine 10
Asp 9
MAP 9
Tamoxifen 9
DFS 9
Tamoxifen 9
Ile 9
CAP 9
CAP 8
Adriamycin 8
Phe 8
Curcumin 8
sulfate 8
zinc 7
PMA 7
iodine 7
vitamin D 7
His 7
MDR 7
DSM 7
VP-16 6
CTX 6
COS 6
ethanol 6
proline 6
CAT 6
CAT 6
NH2 6
DTPA 6
BCR 6
potassium 6
MEK 6
more...