Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:O75628 (
REM
)
5,581
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
REM
5581
Sep
357
dream
222
orexin
154
SWS
113
GABA
91
growth hormone
70
CO2
56
MRI
48
cage
43
Mem
38
prolactin
36
HLA
34
SWA
34
CSF
33
melanin-concentrating hormone
32
CA1
32
Mot
31
CPAP
30
olfactory
30
Orexin
30
Mol
29
PSG
26
beta-endorphin
24
ACTH
23
ANOVA
22
insulin
20
tyrosine hydroxylase
19
Pol
19
rhodanese
19
5-HT1A
18
muscarinic receptor
18
hemoglobin
17
acetylcholinesterase
17
COPD
16
P300
15
cytokine
15
PPT
15
GABA(A) receptor
14
leptin
14
more...
Disease
depression
432
sleep disorders
319
narcolepsy
252
sleep apnea
250
obstructive sleep apnea
234
sleep disturbances
218
epilepsy
175
Parkinson's disease
175
cataplexy
154
REM sleep behavior disorder
120
major depressive disorder
118
SWS
114
SWS
113
dementia
106
hallucinations
95
Alzheimer's disease
82
parasomnia
77
schizophrenia
75
behavior disorder
61
cognitive impairment
57
obesity
53
restless legs syndrome
49
sleepwalking
46
psychosis
45
chronic obstructive pulmonary disease
43
hypertension
43
SEM
39
clinical depression
38
posttraumatic stress disorder
37
cold
35
parkinsonism
35
stroke
31
movement disorder
30
fits
29
affective disorder
28
sudden infant death syndrome
28
disinhibition
26
anxiety disorders
24
aggression
23
bruxism
23
more...
Symptom
sleepiness
396
insomnia
283
seizures
161
hypersomnia
99
snoring
77
pain
72
anesthesia
65
fatigue
57
hypercapnia
54
myoclonus
38
headache
37
tremor
30
eds
29
weakness
27
twitching
22
agitation
21
dystonia
20
hypotonia
17
enuresis
17
ataxia
16
constipation
15
discomfort
12
discomfort
12
collapse
11
cough
11
analgesia
11
hypothermia
11
bradykinesia
11
dyspnea
11
anosmia
10
hypocapnia
10
overweight
9
hangover
9
CSR
8
vomiting
7
Periodic breathing
7
syncope
7
chorea
7
tachypnea
7
Poor sleep
7
more...
Drug
CSF
33
caffeine
28
Flurazepam
10
Zonisamide
10
Monit
10
Nephron
8
Clonidine
7
Spectrum
7
Frontal
7
Flunitrazepam
7
Diurnal
7
Apomorphine
6
Portal
6
Ethanol
6
Theophylline
6
Trimipramine
5
MDS
5
Brotizolam
5
Triazolam
5
Modafinil
5
CTX
4
DHT
4
DHT
4
Growth hormone
4
9-THC
4
Spectrum
4
DMI
4
MAP
4
Atropine
4
Growth hormone
4
LAAM
3
Cardiovasc
3
Dermatol
3
Scopolamine
3
Leaf
3
ROC
3
Histamine
3
Dormicum
3
Phentolamine
3
TMS
2
more...
Enzyme
monoamine oxidase
27
acetylcholinesterase
23
tyrosine hydroxylase
18
LDT
17
choline acetyltransferase
13
renin
11
cholinesterase
9
Alternating
9
FFT
9
SPT
6
ATPase
6
SPT
6
protein kinase
6
ACE
5
NO synthase
5
adenosine deaminase
5
adenosine deaminase
5
DAT
5
mitogen-activated protein kinase
5
catalase
4
ERK
4
peroxidase
4
NADPH-diaphorase
4
focal adhesion kinase
4
dopamine beta-hydroxylase
4
histidine decarboxylase
3
superoxide dismutase
3
CaMKII
3
aspartate aminotransferase
3
phospholipase C
2
arginase
2
PAM
2
CPT
2
acid phosphatase
2
alanine aminotransferase
2
5alpha-reductase
2
PCP
2
5alpha-reductase
2
glutathione peroxidase
2
cytochrome oxidase
2
more...
Compound
Clin
533
Dec
430
oxygen
202
water
94
GABA
92
GABA
91
CO2
72
5-HT
65
noradrenaline
52
ethanol
49
calcium
41
glutamate
37
DSM
35
glucose
31
sodium
29
caffeine
28
ACTH
26
tryptophan
24
tryptophan
22
tryptophan
22
tryptophan
22
nitric oxide
17
arginine
17
TSH
17
Zolpidem
16
His
15
DNA
15
Clonazepam
15
potassium
14
NMDA
14
gamma-aminobutyric acid
13
Melatonin
13
TRH
12
L-DOPA
12
cAMP
11
acetate
11
Adenosine
11
hydrogen
10
palmitic acid
10
ACh
10
more...