Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:O75628 (REM)
5,581 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
REM 5581
Sep 357
dream 222
orexin 154
SWS 113
GABA 91
growth hormone 70
CO2 56
MRI 48
cage 43
Mem 38
prolactin 36
HLA 34
SWA 34
CSF 33
melanin-concentrating hormone 32
CA1 32
Mot 31
CPAP 30
olfactory 30
Orexin 30
Mol 29
PSG 26
beta-endorphin 24
ACTH 23
ANOVA 22
insulin 20
tyrosine hydroxylase 19
Pol 19
rhodanese 19
5-HT1A 18
muscarinic receptor 18
hemoglobin 17
acetylcholinesterase 17
COPD 16
P300 15
cytokine 15
PPT 15
GABA(A) receptor 14
leptin 14
more...
Disease
depression 432
sleep disorders 319
narcolepsy 252
sleep apnea 250
obstructive sleep apnea 234
sleep disturbances 218
epilepsy 175
Parkinson's disease 175
cataplexy 154
REM sleep behavior disorder 120
major depressive disorder 118
SWS 114
SWS 113
dementia 106
hallucinations 95
Alzheimer's disease 82
parasomnia 77
schizophrenia 75
behavior disorder 61
cognitive impairment 57
obesity 53
restless legs syndrome 49
sleepwalking 46
psychosis 45
chronic obstructive pulmonary disease 43
hypertension 43
SEM 39
clinical depression 38
posttraumatic stress disorder 37
cold 35
parkinsonism 35
stroke 31
movement disorder 30
fits 29
affective disorder 28
sudden infant death syndrome 28
disinhibition 26
anxiety disorders 24
aggression 23
bruxism 23
more...
Symptom
sleepiness 396
insomnia 283
seizures 161
hypersomnia 99
snoring 77
pain 72
anesthesia 65
fatigue 57
hypercapnia 54
myoclonus 38
headache 37
tremor 30
eds 29
weakness 27
twitching 22
agitation 21
dystonia 20
hypotonia 17
enuresis 17
ataxia 16
constipation 15
discomfort 12
discomfort 12
collapse 11
cough 11
analgesia 11
hypothermia 11
bradykinesia 11
dyspnea 11
anosmia 10
hypocapnia 10
overweight 9
hangover 9
CSR 8
vomiting 7
Periodic breathing 7
syncope 7
chorea 7
tachypnea 7
Poor sleep 7
more...
Drug
CSF 33
caffeine 28
Flurazepam 10
Zonisamide 10
Monit 10
Nephron 8
Clonidine 7
Spectrum 7
Frontal 7
Flunitrazepam 7
Diurnal 7
Apomorphine 6
Portal 6
Ethanol 6
Theophylline 6
Trimipramine 5
MDS 5
Brotizolam 5
Triazolam 5
Modafinil 5
CTX 4
DHT 4
DHT 4
Growth hormone 4
9-THC 4
Spectrum 4
DMI 4
MAP 4
Atropine 4
Growth hormone 4
LAAM 3
Cardiovasc 3
Dermatol 3
Scopolamine 3
Leaf 3
ROC 3
Histamine 3
Dormicum 3
Phentolamine 3
TMS 2
more...
Enzyme
monoamine oxidase 27
acetylcholinesterase 23
tyrosine hydroxylase 18
LDT 17
choline acetyltransferase 13
renin 11
cholinesterase 9
Alternating 9
FFT 9
SPT 6
ATPase 6
SPT 6
protein kinase 6
ACE 5
NO synthase 5
adenosine deaminase 5
adenosine deaminase 5
DAT 5
mitogen-activated protein kinase 5
catalase 4
ERK 4
peroxidase 4
NADPH-diaphorase 4
focal adhesion kinase 4
dopamine beta-hydroxylase 4
histidine decarboxylase 3
superoxide dismutase 3
CaMKII 3
aspartate aminotransferase 3
phospholipase C 2
arginase 2
PAM 2
CPT 2
acid phosphatase 2
alanine aminotransferase 2
5alpha-reductase 2
PCP 2
5alpha-reductase 2
glutathione peroxidase 2
cytochrome oxidase 2
more...
Compound
Clin 533
Dec 430
oxygen 202
water 94
GABA 92
GABA 91
CO2 72
5-HT 65
noradrenaline 52
ethanol 49
calcium 41
glutamate 37
DSM 35
glucose 31
sodium 29
caffeine 28
ACTH 26
tryptophan 24
tryptophan 22
tryptophan 22
tryptophan 22
nitric oxide 17
arginine 17
TSH 17
Zolpidem 16
His 15
DNA 15
Clonazepam 15
potassium 14
NMDA 14
gamma-aminobutyric acid 13
Melatonin 13
TRH 12
L-DOPA 12
cAMP 11
acetate 11
Adenosine 11
hydrogen 10
palmitic acid 10
ACh 10
more...