Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:O75191 (H. influenzae)
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Human Gene/Protein
H. influenzae 4961
MIC 406
Sep 349
Pseudomonas 295
membrane protein 178
lipopolysaccharide 141
Mol 121
CSF 77
reductase 71
TEM 69
IgA 66
NAD 49
GPT 46
protein D 39
MRSA 39
transferrin 38
PRP 36
NMR 35
Gen 32
SDS 31
hemoglobin 31
ATP 30
endonuclease 29
polypeptide 25
Rec 25
Hepp 24
porin 23
IL-8 22
C-reactive protein 22
haptoglobin 21
CO2 20
PISP 20
PRSP 19
TMP 19
IgA1 18
cryptic 18
ESI 18
IL-6 18
albumin 17
hinge 17
lactoferrin 17
NADPH 17
ENT 17
fused 16
kit 16
glycosyltransferase 16
AMP 16
cytokine 16
Gal 16
COPD 16
Pol 15
LPS 15
HP1 15
CRP 15
UTI 14
API 14
glycoprotein 14
tumor necrosis factor 14
IgE 13
tRNA 13
transaldolase 12
transketolase 12
catalase 12
unknown function 12
E. coli) 11
19A 11
serum albumin 11
hormone receptor 11
TLR4 11
mucin 10
erm 10
IgG3 10
surface antigen 10
superoxide dismutase 10
ATPase 10
peroxidase 10
methyltransferase 10
PBP 10
hemopexin 10
TNF-alpha 10
CD4 9
vitronectin 9
NADH 9
TLR2 9
K100 9
DNA gyrase 9
NADP 9
CD14 8
serine protease 8
CAP 8
lactate dehydrogenase 8
fibronectin 8
She 8
plasminogen 8
IL-10 8
TOF 8
OMP 8
BRL 8
aldose reductase 8
CPZ 8
phosphatase 8
factor V 7
housekeeping 7
IFN-gamma 7
chemokine 7
beta 1 7
CTX 7
dimeric 7
SOD 7
glucosamine 7
transferrin receptor 7
ORF 7
interleukin-6 6
ABC transporter 6
IL-1 beta 6
tumor necrosis factor alpha 6
TAL1 6
peptide deformylase 6
Polymerase 6
factor H 6
ribosomal protein 6
VIII 6
DPT 6
ABC 6
MLS 6
gut 6
CTM 6
5'-nucleotidase 6
Met 6
ACS 6
phosphoglucose isomerase 6
deoxyribonuclease 5
IL-5 5
mer 5
glutaredoxin 5
intercellular adhesion molecule-1 5
myeloperoxidase 5
lymphoid 5
serum protein 5
membrane-bound 5
MHA 5
DNase I 5
CD8 5
ADP 5
endothelin receptor 5
San 5
tap 5
lysozyme 5
TLR9 5
sugar transporter 5
FEV 5
lectin 5
integrase 5
heavy chain 5
CMP 5
sialyltransferase 5
L22 5
PRL 5
alcohol dehydrogenase 5
Mal 5
more...
Disease
Haemophilus 3873
meningitis 652
pneumonia 480
otitis media 303
Klebsiella 245
bacterial meningitis 241
acute otitis media 209
bacteremia 197
middle ear 167
chronic bronchitis 155
sepsis 145
infectious diseases 136
influenza 123
bronchitis 119
sinusitis 115
chronic obstructive pulmonary disease 112
sepsis 98
Proteus 96
Mycoplasma 92
bacterial infection 91
respiratory infection 89
tonsillitis 74
Infection 74
cystic fibrosis 72
pertussis 71
TEM 69
TEM 69
epiglottitis 65
bacterial pneumonia 61
otitis 60
diphtheria 57
Chlamydia 56
Legionella 55
urinary tract infection 54
bronchitis 53
cellulitis 52
bronchiectasis 50
tetanus 43
chancroid 41
conjunctivitis 41
Haemophilus influenzae meningitis 40
MRSA 39
septic arthritis 36
eosinophilia 36
Brazilian purpuric fever 36
tuberculosis 35
virus infection 34
Bordetella 34
pharyngitis 33
asthma 33
acute sinusitis 32
SDS 31
middle ear effusion 31
osteomyelitis 30
HIV 29
chronic otitis media 28
bronchopneumonia 28
empyema 28
meningococcal meningitis 27
arthritis 26
lymphadenitis 26
pyelonephritis 25
chronic sinusitis 24
Infections 23
acute tonsillitis 23
immunodeficiency 22
cold 21
respiratory disease 21
lung disease 20
Mycobacterium 20
rash 19
cholera 19
multiple myeloma 19
endocarditis 19
hepatitis B 18
measles 17
diabetes 17
peritonitis 17
COPD 16
upper respiratory infection 16
Middle ear 16
cancer 15
HP1 15
acute pharyngitis 15
pericarditis 15
Poland 14
neutropenia 14
systemic disease 14
Shigella 14
Haemophilus infections 14
polio 13
Mycoplasma pneumoniae pneumonia 13
enteritis 13
West 13
swine influenza 13
aseptic meningitis 12
herpes simplex 12
mumps 12
Yersinia 12
gonococcal 12
AIDS 12
meninges 12
emphysema 11
stroke 11
malnutrition 11
Haemophilus influenzae pneumonia 11
sickle cell disease 11
thrombocytosis 10
lobar pneumonia 10
HMR 10
fits 10
scarlet fever 10
brain abscess 9
salmonellosis 8
rubella 8
mastoiditis 8
recurrent tonsillitis 8
streptococcal pharyngitis 8
malaria 8
enterocolitis 8
respiratory failure 8
anemia 8
encephalitis 8
CAP 8
coma 8
chest infection 8
hypogammaglobulinemia 8
deafness 8
meningoencephalitis 8
viral meningitis 8
atypical pneumonia 8
hydrocephalus 7
rhinitis 7
conjunctiva 7
bronchiolitis 7
typhoid 7
lung cancer 7
varicella 7
secondary infection 7
CTX 7
purpura 7
lung abscess 7
acute conjunctivitis 6
cytomegalovirus 6
PCP 6
MLS 6
asthmatic bronchitis 6
pharyngotonsillitis 6
periodontitis 6
CTM 6
epilepsy 6
abortion 5
viral pneumonia 5
impetigo 5
pneumoconiosis 5
pharyngolaryngitis 5
mimicry 5
Adenovirus 5
pyothorax 5
scalded skin syndrome 5
more...
Symptom
diarrhea 64
cough 27
vomiting 19
dyspnea 18
ENT 17
pain 14
nausea 12
seizures 11
abdominal pain 10
nasal discharge 9
anesthesia 8
respiratory distress 8
rhinorrhea 7
headache 7
agitation 5
discomfort 5
discomfort 5
erythema 5
starvation 5
tachypnea 4
wheezing 4
stridor 4
lethargy 4
apathy 4
consciousness disturbance 3
weakness 3
twitching 3
ataxia 3
sore throat 3
otalgia 3
facial pain 3
rales 3
anorexia 2
fever of unknown origin 2
chills 2
productive cough 2
hypothermia 2
chronic cough 2
cyanosis 2
Ill 2
dizziness 2
tremor 2
paresis 1
anal pain 1
sneezing 1
non-productive cough 1
fatigue 1
analgesia 1
urinary frequency 1
swollen joints 1
collapse 1
arthralgia 1
hypoproteinemia 1
chest pain 1
Gastrointestinal symptoms 1
nasal congestion 1
hip pain 1
nausea and vomiting 1
angina 1
No adverse effect 1
dental pain 1
hemiplegia 1
hoarseness 1
eye discharge 1
back pain 1
incoordination 1
drooling 1
splenomegaly 1
Mills 1
sleepiness 1
abdominal cramps 1
hemoptysis 1
shortness of breath 1
blurred vision 1
dysuria 1
Drug
ampicillin 757
CSF 78
Azithromycin 39
AMC 29
IPM 25
Amoxicillin 21
Cefaclor 18
lactose 18
Cefditoren 18
ENT 17
Moxifloxacin 16
SBT 15
Zinat 14
Ceftazidime 14
CMZ 13
Meropenem 13
CEZ 13
Meropenem 13
lysine 12
Ofloxacin 11
CVA 11
Asn 11
CTM 11
NADH 9
AZT 8
CPZ 8
OMP 8
Fraction 8
Felodipine 8
Gatifloxacin 8
CTX 7
CMNX 7
IFN-gamma 7
CTX 7
CTRX 7
PAPM/BP 7
CTX 7
Gemifloxacin 6
Piperacillin 6
LMOX 6
CTM 6
Heme 6
Loracarbef 6
ABC 6
Augmentin 6
Gel 5
CXM 5
Asthma 5
Tosufloxacin 5
Augmentin 5
Cefprozil 5
Doyle 5
DNase I 5
CFDN 5
FMOX 5
PCP 4
LVFX 4
CMX 4
EPI 4
Cefmenoxime 4
Cefetamet 4
MEPM 4
Dirithromycin 4
Cefpiramide 3
Oxacillin 3
Trimethoprim-sulfamethoxazole 3
CZX 3
Glutathione 3
Histamine 3
Temocillin 3
Cefroxadine 3
MAP 3
CDX 3
CDP 3
Ethanol 3
CFS 3
Trib 3
Panipenem 3
Ceftibuten 3
CAZ 3
Cefuzonam 3
ROS 2
OFLX 2
NAG 2
CTT 2
Spectrum 2
CaCl2 2
Check 2
CaCl2 2
CaCl2 2
citric acid 2
TMS 2
Ertapenem 2
ZnCl2 2
Spectrum 2
CPFX 2
Prulifloxacin 2
ZnCl2 2
Leaf 2
CPFX 2
CEX 2
CET 2
THF 2
CFX 2
AZT 2
Sultamicillin 2
CFT 2
CZON 2
CPDX-PR 2
BCG vaccine 1
O-Acetylserine 1
Bactrim 1
APD 1
Mutagen 1
Mezlocillin 1
Pertussis vaccine 1
CZOP 1
Galactose 1
Garenoxacin mesylate 1
Amdinocillin 1
G418 1
Benserazide 1
ACT 1
Doxycycline 1
Acacia 1
ALA 1
TAC 1
Alliance 1
ICI 1
AMK 1
Rokitamycin 1
CPM 1
CFPN-PI 1
MINO 1
Budesonide 1
SPFX 1
CTC 1
Itraconazole 1
Intal 1
Ganciclovir 1
Honey 1
PE2 1
Rhamnose 1
Alanine 1
Bayer 1
VCR 1
ENX 1
NVP 1
AraC 1
pyridoxal phosphate 1
Rocephin 1
Rayon 1
Phenoxymethylpenicillin 1
TFLX 1
CTC 1
CAM 1
ETA 1
NFLX 1
ROC 1
Vitamin A 1
more...
Enzyme
beta-lactamase 725
xylulokinase 160
xylose isomerase 63
xylitol dehydrogenase 61
xylitol dehydrogenase 61
alanine aminotransferase 46
IgA1 protease 43
endonuclease 29
IgA protease 18
peroxidase 17
superoxide dismutase 13
chloramphenicol acetyltransferase 13
catalase 12
transketolase 12
trypsin 12
penicillin binding protein 12
transaldolase 12
proteinase K 11
transpeptidase 10
ATPase 10
lactate dehydrogenase 10
DNase 9
topoisomerase 9
topoisomerase 9
urease 8
aldose reductase 8
urease 8
deoxyribonuclease 8
RNA polymerase 7
alkaline phosphatase 6
lysozyme 6
phosphoglucose isomerase 6
arabitol dehydrogenase 6
alcohol dehydrogenase 6
ACS 6
5'-nucleotidase 6
deoxyribonuclease 6
glycerophosphodiester phosphodiesterase 6
phosphoketolase 5
peptide deformylase 5
peroxiredoxin 5
ribulokinase 5
pepsin 5
beta-galactosidase 5
sialyltransferase 5
glutathione S-transferase 5
sialyltransferase 5
sialyltransferase 5
HtrA 4
ribose-5-phosphate isomerase 4
nitrate reductase 4
BAL 4
nitrate reductase 4
glycerol kinase 4
nitrate reductase 4
aldolase 4
nitrate reductase 4
PCP 4
mitogen-activated protein kinase 4
malate dehydrogenase 4
tryptophan 2,3-dioxygenase 4
nitrate reductase 4
nitrate reductase 4
neuraminidase 4
dihydrofolate reductase 4
pyruvate dehydrogenase 4
tryptophanase 4
ornithine decarboxylase 4
phosphofructokinase 3
endodeoxyribonuclease 3
pyruvate decarboxylase 3
glyceraldehyde-3-phosphate dehydrogenase 3
lysine decarboxylase 3
acid phosphatase 3
CMP-Neu5Ac synthetase 3
glucose-6-phosphate dehydrogenase 3
nucleotidase 3
elastase 3
signal peptidase II 3
neutrophil elastase 3
PAL 3
C3 convertase 3
choline kinase 3
plasmin 3
MAP 3
DNA polymerase 3
PAL 3
pyruvate kinase 3
CDR 3
collagenase 3
6-phosphogluconate dehydrogenase 3
transcriptase 3
polyphosphate kinase 2
glyceraldehyde-3-phosphate dehydrogenase 2
phospholipase C 2
hexokinase 2
glucose dehydrogenase 2
adenylate kinase 2
phospholipase A2 2
prephenate dehydrogenase 2
DNA ligase 2
prephenate dehydrogenase 2
PARP 2
CD10 2
xylanase 2
glyceraldehyde-3-phosphate dehydrogenase 2
beta-glucosidase 2
4-epimerase 2
CMP-KDO synthetase 2
nitrite reductase 2
ribulose 5-phosphate 3-epimerase 2
nitrite reductase 2
Pla 2
glyceraldehyde-3-phosphate dehydrogenase 2
chorismate mutase 2
6-phosphogluconate dehydrogenase 2
C3 convertase 2
nitrite reductase 2
glyceraldehyde-3-phosphate dehydrogenase 2
factor D 2
thrombin 2
aspartate aminotransferase 2
beta-xylosidase 2
adenylate cyclase 2
beta-glucosidase 2
xylanase 2
pseudouridine synthase 2
tissue plasminogen activator 2
pyruvate oxidase 2
galactokinase 2
APC 2
glycinamide ribonucleotide transformylase 2
ribonuclease 2
mannitol 2-dehydrogenase 2
luciferase 2
pyruvate oxidase 2
DNA methyltransferase 2
urokinase-type plasminogen activator 2
RNase 2
dihydropteroate synthase 2
DNA ligase 2
aldehyde dehydrogenase 2
ribonuclease 2
SPC 2
ribokinase 2
RNase 2
reverse transcriptase 2
GAR 2
thymidylate synthase 2
acetolactate synthase 1
ClpP 1
alpha-ketoglutarate dehydrogenase 1
PRE 1
CEP 1
succinate dehydrogenase 1
argininosuccinate synthetase 1
CMP kinase 1
enoyl-ACP reductase 1
phospholipase D 1
succinic dehydrogenase 1
more...
Compound
Clin 506
MIC 406
DNA 401
Dec 328
xylose 157
glucose 142
phosphate 141
BRL 96
sodium 74
TEM 69
ethanol 67
Penicillin 64
iron 60
pentose 56
NAD 53
Penicillin 52
galactose 50
NAD 49
sulfate 48
pentose 46
GPT 46
pentose 46
pentose 46
heptose 44
heptose 44
heptose 44
oxygen 41
Azithromycin 39
SDS 39
CAM 31
ATP 30
hexose 28
hexose 28
hexose 28
hexose 28
Amoxicillin 26
water 26
Ceftriaxone 25
CO2 24
lysine 23
Clarithromycin 22
Telithromycin 22
nicotinamide 21
His 20
Cefotaxime 20
Ciprofloxacin 19
TMP 19
TMP 19
Imipenem 19
TMP 19
zinc 19
TMP 19
EDTA 19
alanine 18
EDTA 18
Cefaclor 18
hydrogen 17
NADPH 17
Levofloxacin 17
acetate 17
AMP 17
NADPH 17
Asp 16
Erythromycin 16
Moxifloxacin 16
cysteine 15
Xylose 15
threonine 15
Neu5Ac 15
glycerol 14
NADP 14
MBC 14
Methicillin 14
nitrogen 14
Cefuroxime 14
Ceftazidime 14
MBC 14
Cefixime 13
serine 12
nitrate 12
GalNAc 12
phenol 12
Optimal 12
T 1 12
Ofloxacin 11
bromide 11
methionine 11
leucine 11
Tobramycin 11
Ile 10
Gly 10
Phosphorylcholine 10
tyrosine 10
copper 9
Vancomycin 9
potassium 9
NADH 9
Chlorpromazine 8
GlcNAc 8
ammonium 8
CAP 8
arginine 8
OMP 8
CPZ 8
TOF 8
Trimethoprim 8
cAMP 8
calcium 8
CAP 8
salt 8
Ceftizoxime 8
Heme 8
GM1 7
BCG 7
Linezolid 7
CTX 7
Gatifloxacin 7
NMN 7
Cefoperazone 7
asparagine 7
Triton X-100 7
ABT-773 7
Cefdinir 7
Aztreonam 7
urea 6
DEAE 6
A 3 6
CoA 6
Tetracycline 6
acetone 6
alcohol dehydrogenase 6
Cefozopran 6
Rifampicin 6
Loracarbef 6
Piperacillin 6
DPT 6
Agar 6
nickel 6
ACS 6
ACS 6
Tigecycline 6
pyrimidine 5
Mg2+ 5
Cefuroxime axetil 5
cyanide 5
GSH 5
tryptophan 5
Xylitol 5
6-12 5
Sulbactam 5
A 1 5
Dexamethasone 5
Sparfloxacin 5
PCP 5
pyridine 5
chloroform 5
Tazobactam 5
TMB 5
Clavulanic acid 5
ADP 5
more...