Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:O60502 (N-acetyl-beta-D-glucosaminidase)
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Human Gene/Protein
N-acetyl-beta-D-glucosaminidase 14.3
FGF-5S 12.3
FBXW10 11.5
MGEA5 11.1
NAG-2 11.1
NAG 11.1
VGLL3 10.6
ZNF335 10.6
O-GlcNAcase 10.4
Ss blood group 10.4
AMBP 10.1
NPM3 10.1
NAGA 9.8
O-GlcNAc transferase 9.8
lysosomal acid beta-galactosidase 9.8
DPP II 9.7
CHN1 9.7
beta 2-microglobulin 9.7
chitobiase 9.6
fucosyltransferase 1 9.6
alpha-L-fucosidase 9.6
Beta-2-microglobulin 9.5
Angiotensin I converting enzyme 9.3
GALA 9.3
ACS5 9.2
PLEKHM1 9.2
Muramidase 9.1
Glutamine:fructose-6-phosphate amidotransferase 9.0
ACS3 8.9
PEG1 8.8
gamma-glutamyltransferase 8.7
retinol-binding protein 8.7
beta-2-microglobulin 8.6
CBP1 8.6
acid alpha-glucosidase 8.5
GPAM 8.5
Trf 8.5
Acid phosphatase 8.5
beta-glucuronidase 8.4
gamma-glutamyltranspeptidase 8.4
gamma-glutamyl transpeptidase 8.4
ACS4 8.4
SKAP-55 8.3
Hexosaminidase 8.3
Endo-beta-N-acetylglucosaminidase 8.2
Beta-galactosidase 8.1
arylsulphatase 8.0
alpha-mannosidase 8.0
CHK 7.9
Glycosyltransferase 7.9
Lysophospholipase 7.9
MPS-1 7.9
GlcNAc transferase 7.9
alkaline phosphomonoesterase 7.8
urate transporter 1 7.8
leucine aminopeptidase 7.7
acidic mammalian chitinase 7.7
DRPLA 7.6
aspartylglucosaminidase 7.6
ACO2 7.6
AQP2 protein 7.6
neutrophil gelatinase-associated lipocalin 7.6
SE2 7.5
acid phosphatase 7.5
glycoprotein alpha 7.5
alpha-glucosidase 7.5
AMFR 7.5
intestinal alkaline phosphatase 7.4
alkaline phosphodiesterase I 7.4
Alb 7.4
betaglycan 7.3
Extracellular superoxide dismutase 7.2
D-amino-acid oxidase 7.2
CHN2 7.2
cytosolic malate dehydrogenase 7.2
arylsulfatase 7.2
kidney injury molecule 1 7.1
LDH-X 7.1
cysteine conjugate beta-lyase 7.1
cathepsin D 7.1
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Disease
Serum potassium increased 10.7
pancreatic islet hyperplasia 10.3
Neuroinfections 9.9
MF4 9.7
recurrent osteosarcoma 8.8
Idiopathic hypercalciuria 8.3
Unicameral bone cyst 8.3
lower urinary tract infection 8.0
corneal degeneration 7.8
Medulla 7.7
carcinoma of the uterus 7.7
tubular necrosis 7.7
Microscopic polyangiitis 7.7
pulmonary granuloma 7.6
renal glycosuria 7.6
Goldblatt hypertension 7.6
BEN 7.6
microalbuminuria 7.5
diabetic cataract 7.5
Mastitis 7.5
hemoglobinemia 7.4
uricosuria 7.4
Thorn 7.2
Proteinuria 7.2
aminoaciduria 7.1
uncomplicated hypertension 7.0
hypertensive nephropathy 7.0
diabetic nephropathy 6.9
mastitis 6.8
Aspartylglucosaminuria 6.8
nephrocalcinosis 6.8
pseudohypoparathyroidism 6.8
Granuloma 6.7
DBA2 6.7
proteinuria 6.7
borderline hypertension 6.6
acute undifferentiated leukemia 6.6
nephrosclerosis 6.6
fucosidosis 6.5
ASAT 6.5
Ototoxicity 6.4
GM2 gangliosidosis 6.4
neonatal asphyxia 6.3
GSD I 6.2
chronic glomerulonephritis 6.2
acute renal failure 6.2
renal papillary necrosis 6.1
acute cystitis 6.1
ACS1 6.1
Interstitial fibrosis 6.1
Hemorrhagic fever with renal syndrome 6.0
pelvic cancer 6.0
cystinosis 6.0
hemoglobinuria 6.0
pyuria 5.9
Superinfection 5.8
azotemia 5.8
hypercalciuria 5.8
renal impairment 5.8
pyelonephritis 5.7
LAP 5.6
Sezary syndrome 5.6
renal ischemia 5.5
acute tubular necrosis 5.5
hepatic veno-occlusive disease 5.4
hyperoxaluria 5.4
renal disease 5.4
nephritis 5.3
Sandhoff disease 5.3
Lyme arthritis 5.3
nephrotic syndrome 5.3
hepatorenal syndrome 5.3
PHP 5.2
western equine encephalomyelitis 5.2
cholesterolemia 5.2
Fanconi syndrome 5.2
MTC 5.1
subacute thyroiditis 5.1
uropathy 5.1
interstitial nephritis 5.0
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Symptom
cardiovascular impairment 7.5
polyuria 6.3
lassitude 6.1
oliguria 5.7
rundown 5.3
hypoproteinemia 5.1
polydipsia 4.2
urinary frequency 4.1
enuresis 3.6
tense 3.2
pallor 3.0
Wind 2.9
starvation 2.5
nausea and vomiting 2.0
respiratory distress 2.0
numbness 1.9
shortness of breath 1.9
anesthesia 1.6
overweight 1.6
functional recovery 1.5
dizziness 1.0
constipation 0.9
exhaustion 0.5
anorexia 0.5
collapse 0.5
ataxia 0.3
hypothermia 0.2
tremor 0.1
diarrhea 0.0
cough -0.3
fatigue -0.4
abdominal pain -0.7
vomiting -0.7
weakness -1.0
Drug
Halopredone acetate 12.7
Sergliflozin 11.9
Iodamide 11.7
Ioxilan 10.9
Pro-Banthine 10.8
Y-700 10.8
Cupric sulfate 10.3
Leucin 9.9
NAG 9.9
Alacepril 9.6
Muzolimine 9.5
Ulinastatin 9.4
Dazmegrel 8.9
Cilastatin 8.8
Epalrestat 8.6
Monarch 7.8
APM 7.8
Mineral oil 7.4
Protamine sulfate 7.3
Compound 15 7.3
Lead acetate 7.0
CET 6.9
Iohexol 6.9
Conray 6.8
Diamminedichloroplatinum 6.6
beta-Galactosidase 6.5
Mesalazine 6.4
Bestatin 6.1
Aprotinin 6.0
Perindopril 5.9
Lactose 5.7
Alanine 5.6
Olive oil 5.6
Nephron 5.6
Ramipril 5.5
Albumin 5.3
MTC 5.3
Cellulase 5.3
Acyclovir 5.2
Salicylate 5.1
Nephron 5.0
Hypaque 5.0
Ganciclovir 4.7
Vitamin A 4.7
Rosiglitazone 4.6
Pravastatin 4.6
Methylprednisolone 4.4
Oxaliplatin 4.4
Hypaque 4.1
Etoposide 4.1
Adriamycin 4.1
Serum albumin 4.0
Pronase 3.9
NBT 3.9
AZT 3.7
VCR 3.6
TAC 3.6
Diurnal 3.5
Fructose 3.4
CTX 3.3
ADR 3.3
lactose 3.2
Indomethacin 3.2
PTH 3.1
Captopril 3.1
Glycerol 3.1
Asn 2.7
SiO2 2.7
CaCl2 2.6
CaCl2 2.6
CaCl2 2.6
Vitamin E 2.6
MRC 2.5
Gel 2.4
niacin 2.4
vitamin E 2.2
nitroglycerin 2.1
ROS 2.0
ampicillin 1.8
TiO2 1.8
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Enzyme
EC 3.2.1.43 14.3
alanine aminopeptidase 11.5
N-acetylgalactosaminidase 11.2
beta-D-fucosidase 11.1
alpha-L-fucosidase 10.5
alpha-L-fucosidase 10.4
alpha-L-fucosidase 10.0
N-acetylglucosamine-6-sulfatase 9.6
O-GlcNAc transferase 9.6
alpha-mannosidase 9.4
CD13 9.2
alpha-N-acetylglucosaminidase 9.0
glutamine transaminase K 8.6
beta-glycerophosphatase 8.5
beta-glucuronidase 8.1
carboxyl proteinase 8.0
gamma-glutamyl transpeptidase 8.0
leucine aminopeptidase 7.8
alpha-galactosidase 7.6
beta-glucosidase 7.6
acid phosphatase 7.5
DAP II 7.5
aspartylglucosaminidase 7.5
acetylserotonin O-methyltransferase 7.5
pantetheinase 7.5
alpha-glucosidase 7.4
transpeptidase 7.3
hexosaminidase 7.3
chitin deacetylase 7.2
tripeptidyl peptidase 7.1
aminopeptidase A 7.1
cathepsin D 7.1
D-amino-acid oxidase 7.0
cysteine conjugate beta-lyase 7.0
glycine amidinotransferase 6.9
dipeptidyl peptidase IV 6.9
5'-nucleotidase 6.7
glucoamylase 6.7
cathepsin C 6.7
beta-xylosidase 6.6
arylsulfatase 6.6
mannanase 6.4
beta-glucosidase 6.4
sulfhydryl oxidase 6.3
N-acetylglucosaminyltransferase 6.3
endoglycosidase H 6.2
beta-galactosidase 6.2
lactate dehydrogenase 6.2
TSP-1 6.1
trehalase 6.0
delta-aminolevulinic acid dehydratase 6.0
ACC oxidase 5.9
beta-1,3-glucanase 5.8
beta-1,3-glucanase 5.8
sorbitol dehydrogenase 5.8
sulfatase 5.8
alpha-L-iduronidase 5.7
beta-hydroxybutyrate dehydrogenase 5.7
lactic acid dehydrogenase 5.7
fructose 1,6-bisphosphatase 5.6
dextranase 5.6
ACC synthase 5.6
cathepsin B 5.6
lactase 5.5
DNase II 5.5
glucose-6-phosphatase 5.5
factor D 5.5
alkaline phosphatase 5.5
lysozyme 5.4
Hageman factor 5.3
sialidase 5.2
adenosine deaminase 4.9
adenosine deaminase 4.9
hyaluronidase 4.9
cellobiohydrolase 4.9
histone acetyltransferase 4.8
SMP 4.8
elastase 4.8
gamma-glutamylcysteine synthetase 4.8
ornithine aminotransferase 4.8
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Compound
C12H17N3O6 14.3
Methyl alpha-D-mannopyranoside 11.1
N-benzoyl-beta-alanine 10.9
p-Anisidine 10.0
decahydronaphthalene 9.2
Merbarone 9.2
decahydronaphthalene 9.1
1-methylpyrrolidine 9.1
N-acetylchitotriose 9.1
Cilastatin 8.8
Guanidinoacetic acid 8.8
Diatrizoate 8.5
Diatrizoate 8.5
iodic acid 8.4
Miglitol 8.4
Hexachlorobutadiene 8.3
N-Acetylglucosamine 8.3
Gentamicin sulfate 8.2
NDPS 8.2
Potassium dichromate 8.1
Nedaplatin 8.1
Gentamicin 8.0
Copper sulfate 7.6
Fleroxacin 7.5
Ferric chloride 7.5
Diamminedichloroplatinum 7.4
Caffeic acid phenethyl ester 7.3
dolichyl-phosphate 7.3
creatinine 7.3
S-allylcysteine 7.3
Thromboxane B2 7.1
GlcNAc 7.0
DCVC 7.0
Cefpirome 6.9
VO4 6.8
Aztreonam 6.7
Fosfomycin 6.7
D-glucosamine 6.7
11-dehydro-thromboxane 6.7
CdCl2 6.6
UDP-GlcNAc 6.6
GA2 6.6
THG 6.6
Netilmicin 6.6
Tetramethylpyrazine 6.6
DAP 6.5
DAP 6.4
HgCl2 6.3
Acridine Orange 6.3
Acridine Orange 6.3
Acridine Orange 6.3
pentanal 6.3
beta-D-galactoside 6.3
pentanal 6.2
Tobramycin 6.1
Perindopril 6.1
01M 6.0
m-cresol 5.9
Hypaque 5.9
TEG 5.9
Bestatin 5.9
Sulindac 5.9
Betamethasone 5.9
gamma-hydroxybutyric acid 5.9
Methimazole 5.9
Glucosamine 5.8
HPT 5.8
1,3-D 5.8
Tunicamycin 5.8
Luminol 5.8
4-nitrophenyl 5.8
Acarbose 5.7
Chloroquine 5.7
Chloroquine 5.7
Desmopressin 5.7
Triton WR-1339 5.7
Inulin 5.7
retinol 5.7
Plasmin 5.6
Lactose 5.6
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