Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:O15085 (PDZ-RhoGEF)
91 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PDZ-RhoGEF 91
RhoA 60
Rho 56
RhoGEF 20
LARG 20
LSC 17
guanine nucleotide exchange factor 17
GTP 16
Mol 12
GTPase 12
pleckstrin 9
RGS 9
plexin 9
GDP 8
small GTPase 7
regulator of G-protein signaling 7
regulator of G protein signaling 7
ARHGEF11 6
GEF 6
axonal 6
insulin 6
RhoC 6
GEF-H1 5
AKT 5
Rho kinase 5
p115 5
SEMA4D 4
PI3K 4
cofilin 4
tyrosine kinase 4
endothelin-1 4
PH domain 4
PAK4 3
thrombin 3
ARHGEF12 3
RhoB 3
PSD-95 3
Sep 3
catenin 2
receptor tyrosine kinase 2
more...
Disease
leukemia 22
tumor 11
RGS 9
cancer 8
Leukemia 5
tumor progression 4
diabetes 4
carcinoma 3
type 2 diabetes 3
tumorigenesis 3
epithelial ovarian cancer 2
breast cancer 2
hypertension 2
acute myeloid leukemia 2
glioblastoma 2
colon cancer 2
obesity 2
lung carcinoma 1
bronchiectasis 1
adenocarcinoma 1
bacterial infection 1
tumor growth 1
blast crisis 1
histiocytic lymphoma 1
erectile dysfunction 1
prostate cancer 1
neuroblastoma 1
lymphoma 1
glioblastoma multiforme 1
fatty liver 1
ATM 1
Hodgkin's disease 1
PML 1
ovarian cancer 1
schizophrenia 1
urethra 1
hepatocellular carcinoma 1
hyperglycemia 1
colorectal cancer 1
glucose intolerance 1
more...
Symptom
collapse 4
dysesthesia 1
starvation 1
paresthesia 1
pain 1
Drug
Mutagen 1
Enzyme
protein kinase 5
mitogen-activated protein kinase 5
thrombin 3
focal adhesion kinase 3
ERK 3
luciferase 2
triphosphatase 1
lipase 1
CaMKII 1
phosphatidylinositol 3-kinase 1
phospholipase C 1
proteasome 1
MMP 1
ATPase 1
NO synthase 1
Compound
GTP 16
Dec 12
GDP 8
serine 4
tyrosine 4
nitric oxide 3
sodium 3
Clin 3
calcium 3
MDA 2
Pima 2
cyclohexanecarboxamide 2
COS 2
threonine 2
DNA 2
glucose 2
cGMP 2
Ile 1
isoleucine 1
ATP 1
Guanine 1
benzamide 1
retinoic acid 1
Nitro-L-arginine 1
glutamic acid 1
Nifedipine 1
isoleucine 1
PEG 1
STZ 1
alanine 1
lysine 1
arginine 1
glutamate 1
PEG 1
salt 1
hydrogen 1
leucine 1
Phe 1