Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:O15085 (
PDZ-RhoGEF
)
91
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PDZ-RhoGEF
91
RhoA
60
Rho
56
RhoGEF
20
LARG
20
LSC
17
guanine nucleotide exchange factor
17
GTP
16
Mol
12
GTPase
12
pleckstrin
9
RGS
9
plexin
9
GDP
8
small GTPase
7
regulator of G-protein signaling
7
regulator of G protein signaling
7
ARHGEF11
6
GEF
6
axonal
6
insulin
6
RhoC
6
GEF-H1
5
AKT
5
Rho kinase
5
p115
5
SEMA4D
4
PI3K
4
cofilin
4
tyrosine kinase
4
endothelin-1
4
PH domain
4
PAK4
3
thrombin
3
ARHGEF12
3
RhoB
3
PSD-95
3
Sep
3
catenin
2
receptor tyrosine kinase
2
more...
Disease
leukemia
22
tumor
11
RGS
9
cancer
8
Leukemia
5
tumor progression
4
diabetes
4
carcinoma
3
type 2 diabetes
3
tumorigenesis
3
epithelial ovarian cancer
2
breast cancer
2
hypertension
2
acute myeloid leukemia
2
glioblastoma
2
colon cancer
2
obesity
2
lung carcinoma
1
bronchiectasis
1
adenocarcinoma
1
bacterial infection
1
tumor growth
1
blast crisis
1
histiocytic lymphoma
1
erectile dysfunction
1
prostate cancer
1
neuroblastoma
1
lymphoma
1
glioblastoma multiforme
1
fatty liver
1
ATM
1
Hodgkin's disease
1
PML
1
ovarian cancer
1
schizophrenia
1
urethra
1
hepatocellular carcinoma
1
hyperglycemia
1
colorectal cancer
1
glucose intolerance
1
more...
Symptom
collapse
4
dysesthesia
1
starvation
1
paresthesia
1
pain
1
Drug
Mutagen
1
Enzyme
protein kinase
5
mitogen-activated protein kinase
5
thrombin
3
focal adhesion kinase
3
ERK
3
luciferase
2
triphosphatase
1
lipase
1
CaMKII
1
phosphatidylinositol 3-kinase
1
phospholipase C
1
proteasome
1
MMP
1
ATPase
1
NO synthase
1
Compound
GTP
16
Dec
12
GDP
8
serine
4
tyrosine
4
nitric oxide
3
sodium
3
Clin
3
calcium
3
MDA
2
Pima
2
cyclohexanecarboxamide
2
COS
2
threonine
2
DNA
2
glucose
2
cGMP
2
Ile
1
isoleucine
1
ATP
1
Guanine
1
benzamide
1
retinoic acid
1
Nitro-L-arginine
1
glutamic acid
1
Nifedipine
1
isoleucine
1
PEG
1
STZ
1
alanine
1
lysine
1
arginine
1
glutamate
1
PEG
1
salt
1
hydrogen
1
leucine
1
Phe
1