Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:O14944 (EPR)
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Human Gene/Protein
EPR 11.2
SDSL 10.3
BOLA1 10.2
ATBT 10.2
TYKY subunit 9.9
TYKY 9.7
tektin 1 9.7
ALKBH4 9.2
ARH2 9.2
TIED 8.9
truncated cytochrome P450 8.9
H5 variant 8.9
RGL2 protein 8.9
CX31 8.7
EPR1 8.7
EPGN 8.7
cycB2 8.7
MCD 8.6
IGL@ 8.4
Miner2 8.4
SH3B 8.2
DYR 8.2
NOV1 8.2
TYW1 8.2
Lipoyl synthase 8.2
PSST 8.2
CFD1 8.1
GRX5 8.1
NADH-cytochrome-b5 reductase 7.9
QPs1 7.9
Acetyl-CoA synthetase 7.9
PrPLP 7.8
Core protein II 7.8
electron transfer flavoprotein-ubiquinone oxidoreductase 7.8
Rieske iron-sulfur protein 7.7
GA protein 7.7
NDUFS6 7.7
RPL36A 7.7
epiregulin 7.6
CRSP70 7.5
coenzyme A synthase 7.5
Constitutive NOS 7.4
sulfite oxidase 7.4
Cysteine dioxygenase 7.4
epithelial mitogen 7.3
Neuregulin 4 7.3
NRG2 7.3
STF1 7.3
complex I) 7.2
D-beta-hydroxybutyrate dehydrogenase 7.2
Ribonucleotide reductase 7.2
HF10 7.2
aconitase 2 7.2
Tew 7.2
ferritin repressor protein 7.1
steroid 11beta-hydroxylase 7.1
A1A 7.1
complexin I 7.1
HL1 7.0
H63 7.0
Ru2 7.0
HL2 7.0
50kD 6.9
elongin A 6.9
T-cell immune regulator 1 6.9
BOLA3 6.9
Sulfite oxidase 6.9
NADH: ubiquinone oxidoreductase 6.9
NDUFAF2 6.9
HAO 6.9
cytochrome b561 6.8
NQO2 6.8
DPP III 6.8
cytochrome bc1 6.8
neuronal PAS domain protein 2 6.8
effector cell protease receptor-1 6.8
ferredoxin 6.8
ribonucleotide reductase 6.8
dipeptidyl peptidase III 6.8
PSST subunit 6.7
more...
Disease
MCD 8.6
Ogo 8.2
irradiated enamel 7.3
Radiation Syndrome 6.9
HPCD 6.6
QPD 6.2
HPS2 6.2
NDI 6.0
DMAT 5.9
Lowe 5.7
Photosensitization 5.7
Lederer 5.6
pseudomembranous enterocolitis 5.5
Hereditary tyrosinemia type I 5.5
Toxicosis 5.4
Photosensitized 5.2
DRS 5.2
Robin 5.2
PAPA 5.2
KNO 5.1
LMS 5.1
CHN 4.8
PMS 4.8
ACV 4.8
CTPA 4.7
PCC 4.7
NHC 4.6
Sweeney 4.6
DRM 4.6
Blastomycosis 4.5
NPHS2 4.5
chronic laryngitis 4.5
BCD 4.4
RHS 4.4
DRD 4.3
DPR 4.3
TAM 4.3
DMC 4.3
Spencer 4.2
favism 4.2
otomycosis 4.2
DMM 4.2
POH 4.2
FDH 4.1
HPP 4.1
HPP 4.0
PLG 4.0
LMS 3.9
LMS 3.9
AA1 3.8
Fibrosarcoma 3.8
Phototoxicity 3.8
HBT 3.7
PMT 3.6
TCO 3.6
TOC 3.6
DMS 3.6
AMN 3.6
MAS 3.6
TEM 3.6
CLS 3.6
subacute sclerosing panencephalitis 3.6
Dicrocoelium dendriticum 3.5
premenstrual syndrome 3.5
TEM 3.5
tumor vasculature 3.5
Buchanan 3.5
TNS 3.5
BOS 3.4
ODA 3.4
BDC 3.4
diabetic hyperglycemia 3.4
CP1 3.4
PPP 3.4
BPS 3.3
pheochromocytoma 3.3
CTM 3.3
CAN 3.2
HBD 3.2
LAD2 3.2
more...
Symptom
catarrh 3.7
tonic seizure 3.5
HSA 3.5
eds 2.8
Halo 2.4
skin damage 2.3
muscle rigidity 2.2
Anoxia 2.1
acidity 1.9
tense 1.7
rigors 1.6
general problem 1.5
twitching 1.3
Hudson 1.2
tonic-clonic seizure 0.9
collapse 0.8
blurred vision 0.2
thinning -0.2
hoarseness -0.3
exertional dyspnea -0.5
exhaustion -0.5
vertigo -0.6
hemiplegia -0.7
wheezing -1.0
starvation -1.0
hyperoxia -1.1
ENT -1.1
tremor -1.3
erythema -1.4
functional recovery -1.5
spasm -1.6
hypercapnia -1.7
seizures -1.9
syncope -1.9
respiratory distress -2.0
cough -2.3
agitation -2.3
weakness -2.4
anesthesia -2.5
anorexia -2.5
dyspnea -2.5
ataxia -2.7
fatigue -2.8
hypothermia -2.8
diarrhea -3.6
pain -5.7
Drug
Ranimustine 8.4
Efaproxiral 8.2
1-Methylimidazole 8.1
Radicut 7.9
Moco 7.9
Uvinul 7.8
Hypophosphite 7.7
Quadramet 7.5
Fosinopril sodium 7.5
BZQ 7.4
RXM 7.4
Peridinin 7.4
Tetrazol 7.3
Hpp 7.3
Bendazac 7.0
Mangafodipir trisodium 6.7
Benzylamine 6.4
CrCl3 6.0
Parsol 6.0
Desferal 5.6
FAD 5.5
CTZ 5.5
THF 5.5
Desferal 5.5
4-Hydroxytamoxifen 5.5
Potato starch 5.3
Violaxanthin 5.3
Nitric Oxide 5.3
C4H10 5.1
Heme 5.0
L-Ser 5.0
Flavin 4.8
Tirapazamine 4.8
Cefaclor 4.7
CSI 4.7
NADH 4.7
-deoxyadenosine 4.6
C4H10 4.6
Doyle 4.6
CPO 4.6
ascorbate 4.5
ISP 4.4
DMAP 4.3
Pertuzumab 4.2
BH4 4.1
Rhamnose 4.1
CLS 4.1
Dithranol 4.0
Riboflavin 4.0
CDP 4.0
Colombo 3.9
Lipiodol 3.9
Guanidine 3.9
Dexrazoxane 3.8
Guanidine 3.8
Atovaquone 3.8
CAZ 3.8
Felodipine 3.7
NH3 3.7
Gemzar 3.7
NBT 3.7
Deferasirox 3.6
FeCl3 3.6
MIL 3.6
Tween 60 3.6
Idarubicin 3.6
Galactose 3.5
PZC 3.5
Tarceva 3.5
Atovaquone 3.4
Pirfenidone 3.4
CTM 3.3
Primaquine 3.3
Crystal Violet 3.3
CoCl2 3.3
CoCl2 3.3
Prozac 3.3
Rasburicase 3.3
Photofrin II 3.2
Levovist 3.2
more...
Enzyme
EC 1.13.11.49 11.2
EC 3.6.3.34 11.2
CbiL 10.2
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 9.7
quinoline 2-oxidoreductase 9.4
3-hydroxy-4-oxoquinoline 2,4-dioxygenase 9.2
isoquinoline 1-oxidoreductase 9.2
2-methyleneglutarate mutase 9.2
2-oxo-1,2-dihydroquinoline 8-monooxygenase 9.2
methylviologen-reducing hydrogenase 8.9
PFL activase 8.9
lysine 2,3-aminomutase 8.7
PebB 8.7
PebA 8.7
2-halobenzoate 1,2-dioxygenase 8.7
SirB 8.7
homoprotocatechuate 2,3-dioxygenase 8.3
FldA 8.2
superoxide reductase 8.1
dimethylamine dehydrogenase 8.1
protocatechuate 4,5-dioxygenase 8.0
ubiquinol-cytochrome c oxidoreductase 7.9
CO dehydrogenase 7.9
CbiX 7.8
biotin synthase 7.8
nitric oxide dioxygenase 7.7
oxalate decarboxylase 7.7
F420-reducing hydrogenase 7.7
EC 1.12.2.1 7.7
quercetinase 7.7
catechol oxidase 7.6
glutamate mutase 7.6
acetylene hydratase 7.5
heterodisulfide reductase 7.5
trimethylamine dehydrogenase 7.4
hydroxylamine oxidoreductase 7.4
sulfite oxidase 7.4
sulfite oxidase 7.3
nitrous oxide reductase 7.3
pyruvate formate-lyase 7.3
rubredoxin reductase 7.3
protocatechuate 3,4-dioxygenase 7.3
cobaltochelatase 7.2
bidirectional hydrogenase 7.2
benzoyl-CoA reductase 7.2
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 7.2
tetrachloroethene reductive dehalogenase 7.2
D-aminopeptidase 7.2
phycocyanobilin:ferredoxin oxidoreductase 7.2
diol dehydratase 7.1
selenate reductase 7.1
enoate reductase 7.1
cytochrome c peroxidase 7.1
undecaprenol kinase 7.1
sulfite reductase 7.0
nicotinic acid hydroxylase 7.0
hydrogenase 7.0
hydrogenase 6.9
acetone carboxylase 6.9
L-ribulose-5-phosphate 4-epimerase 6.9
steroid 11beta-hydroxylase 6.9
methane monooxygenase 6.8
ribonucleotide reductase 6.8
benzylsuccinate synthase 6.7
sulfite reductase 6.7
sulfite reductase 6.7
ribonucleotide reductase 6.7
nitrogenase 6.7
sulfur reductase 6.6
membrane-bound hydrogenase 6.6
ethanolamine ammonia-lyase 6.6
APS reductase 6.5
decarbonylase 6.5
CysG 6.4
nitrite reductase 6.4
pyruvate:ferredoxin oxidoreductase 6.4
camphor hydroxylase 6.4
arsenite oxidase 6.4
nitrite reductase 6.4
nitrite reductase 6.4
more...
Compound
C7H10O6 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C7H10O6 11.2
Lactyl-CoA 11.2
C19H24N2O 11.2
C19H24N2O 11.2
C19H24N2O 11.2
Ethyl Malonate 11.2
C6H4O3 11.2
8-Methylguanine 11.2
C6H15N3 11.2
C19H24N2O 11.2
C7H10O6 11.2
C19H24N2O 11.2
1,4-diphenyl-2-butyne-1,4-dione 11.2
C19H24N2O 11.2
C6H15N3 10.2
C19H24N2O 10.2
C10H10ClNO2 10.2
C6H15N3 10.2
C10H10ClNO2 10.2
C10H10ClNO2 10.2
3-Ethylcatechol 10.2
4-chlorobenzohydrazide 10.2
2-hydroxybenzaldehyde semicarbazone 10.2
C10H10ClNO2 10.2
C10H10ClNO2 10.2
C10H10ClNO2 10.2
C10H10ClNO2 10.2
C10H10ClNO2 10.2
quinoxalino[2,3-b]quinoxaline 10.2
C10H10ClNO2 10.2
C10H10ClNO2 10.2
C10H10ClNO2 10.2
2-hydroxyisonicotinic acid 9.8
7-tridecanol 9.7
C9H8O4 9.7
4-bromo-2-((phenylimino)methyl)phenol 9.7
hydrazinecarbodithioic acid 9.7
C19H24N2O 9.7
2-oxopropylphosphonic acid 9.7
hydrazinecarbodithioic acid 9.7
Eburnamine 9.7
N-(4-chlorophenyl)-N'-hydroxyguanidine 9.7
C7H14O3 9.7
Stigmatellin 9.4
C17H16O4 9.2
1,3,5-cyclohexanetriamine 9.2
TMAT 9.2
4-Chlorophenylacetate 9.2
C19H24N2O 9.2
C40H56 9.2
C40H56 9.2
1-benzyl-1H-1,2,3-triazole 9.2
3-methyl-2,4-pentanedione 9.2
1-Tetralone 9.2
3-methyl-2,4-pentanedione 9.2
C6H12N2O4 9.2
2-methyl-2-nitrosopropane 9.1
Luteoskyrin 9.1
C7H14 8.9
C7H14 8.9
Tempamine 8.9
1H-imidazole-4-carboxylic acid 8.9
C7H14 8.9
C7H14 8.9
C7H14 8.9
C4H4O5 8.9
C4H4O5 8.9
C4H4O5 8.9
C7H14 8.9
more...