Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:B6ZGS9 (
Farnesoid X receptor
)
212
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Farnesoid X receptor
17.2
NR1H4
14.1
bile acid receptor
13.0
M-BAR
12.9
ILBP
12.6
G-protein coupled receptor 5
12.5
SRC2
12.2
bile salt export pump
12.1
SHP
12.1
FXR
12.0
ileal bile acid binding protein
11.6
TGR5
11.5
bile acid-binding protein
11.4
acetyl-CoA carboxylase 2
11.4
CYP8B1
11.3
DDAH-1
11.2
glutamate-cysteine ligase modifier subunit
11.1
PLTP
11.0
multidrug resistance protein 2
10.9
ABCB11
10.8
Histidine-rich glycoprotein
10.8
hyodeoxycholic acid
10.7
GSTA2
10.5
ABCB4
10.5
STAM
10.4
MDR2
10.3
MATE2-K
10.3
CYP7A1
10.3
D3R
10.3
ABCG5
10.3
p-type)
10.2
nuclear receptor
10.2
peptide transporter 1
10.2
farnesoid X receptor
10.1
acetyl-CoA carboxylase 1
10.0
TRAP220
10.0
RBP4
9.9
RNF4
9.9
multidrug resistance-related protein
9.9
SLC22A1
9.9
more...
Disease
Ileum
10.0
ileocolitis
9.5
Spontaneous bacterial peritonitis
9.5
LBD
8.7
cholestasis
8.5
Nonalcoholic fatty liver
8.5
Alcoholic liver disease
8.3
biliary tract cancer
7.8
HEP
7.7
lipid disorder
7.6
fatty liver
7.5
primary sclerosing cholangitis
7.5
Chronic hepatitis B
7.4
biliary atresia
7.1
LDLR
7.1
cholangitis
7.0
tubular necrosis
6.9
bacterial peritonitis
6.8
hepatoblastoma
6.8
short bowel syndrome
6.7
alcoholic fatty liver
6.4
Tumour necrosis
6.3
hyperlipidemia
6.0
liver cancer
6.0
dyslipidemia
6.0
renal ischemia
5.9
gallstones
5.8
liver fibrosis
5.8
idiopathic pulmonary fibrosis
5.8
liver disease
5.7
metabolic syndrome
5.6
liver cancer
5.6
PDB
5.5
failure to thrive
5.5
pruritus
5.4
hepatocellular carcinoma
5.2
chronic liver disease
5.1
portal hypertension
5.0
primary biliary cirrhosis
5.0
glucose intolerance
4.7
more...
Symptom
starvation
2.6
overweight
2.5
diarrhea
2.4
abdominal pain
2.3
Drug
Fexaramine
17.2
Rifaximin
9.5
Pirfenidone
9.3
Simvastatin
6.5
Nitric Oxide
5.9
ALA
5.7
Bifidobacterium
4.7
Gel
3.3
Enzyme
CYP8B1
11.7
CYP7A1
10.4
dihydropyrimidine dehydrogenase
7.5
UDP-glucuronosyltransferase
7.1
dihydropyrimidine dehydrogenase
6.9
gamma-glutamylcysteine synthetase
6.7
acetyl-CoA carboxylase
6.7
Mg2+-ATPase
6.7
paraoxonase
6.5
MPP
6.3
paraoxonase
6.2
AMPK
6.2
phosphoenolpyruvate carboxykinase
6.2
phosphoenolpyruvate carboxykinase
6.2
soluble epoxide hydrolase
6.1
phosphoenolpyruvate carboxykinase
6.0
AMP-activated protein kinase
5.8
carboxylesterase
5.6
arginase
5.3
AMPK
5.2
aldehyde dehydrogenase
5.1
aldehyde dehydrogenase
5.1
aldehyde dehydrogenase
5.1
CPT
5.0
luciferase
5.0
DNA methyltransferase
4.9
aldehyde dehydrogenase
4.9
alanine aminotransferase
4.8
focal adhesion kinase
4.6
CYP3A4
4.6
aldehyde dehydrogenase
4.5
aspartate aminotransferase
4.4
NOS
4.4
glutathione S-transferase
4.3
thymidine kinase
4.3
alcohol dehydrogenase
4.0
mitogen-activated protein kinase
3.8
alkaline phosphatase
3.6
P-glycoprotein
3.5
phospholipase A2
3.4
more...
Compound
Fexaramine
17.2
Yangonin
14.6
Yangonin
14.4
6-ECDCA
14.4
Chenodeoxycholic acid
11.4
DHM
11.4
Imperatorin
10.9
Rilmenidine
10.4
Geniposide
9.9
AF-2
9.7
Farnesol
9.4
Chalcone
9.1
Taurocholate
9.0
glutaryl-CoA
8.8
Probucol
8.5
INT
8.5
8-Br-cGMP
7.8
HEP
7.7
Lycopene
7.7
AICAR
7.5
isoxazole
7.5
Valproic acid
7.2
p-cresol
7.0
chalcone
6.9
DPA
6.7
AICAR
6.7
benzamide
6.6
MCA
6.6
MCA
6.6
p-cresol
6.4
MPP
6.4
MPP
6.4
APAP
6.4
PDB
6.3
Taurine
6.0
Parenteral
5.9
DEHP
5.7
Valproic acid
5.5
INH
5.4
ANA
5.1
more...