Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:B6E4X6 (mutant p53)
3,342 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein mutant p53 3342 p53 3017 p21 314 Mol 301 Sep 211 Bcl-2 143 MDM2 137 tumour suppressor 101 p73 99 p53 target 95 caspase-3 93 bcl-2 87 WAF1 87 ras 85 p63 75 PRIMA 71 proteasome 66 DNA-binding domain 57 PARP 55 Li-Fraumeni syndrome 53 proliferating cell nuclear antigen 52 ubiquitin 52 c-myc 51 CIP1 50 Mdm2 46 osteosarcoma 42 bax 40 erbB-2 39 caspase-9 37 APR 37 cytochrome c 36 estrogen receptor 36 cyclin 35 p16 34 Ki-67 34 Fas 32 Hsp90 32 ATP 31 cyclin D1 31 cytokine 30 more...

Disease cancer 1685 tumor 1424 breast cancer 314 tumorigenesis 244 carcinoma 226 carcinogenesis 197 tumor progression 171 tumor growth 128 lung cancer 121 MCF 115 adenocarcinoma 99 colon cancer 90 hepatocellular carcinoma 86 colorectal cancer 82 squamous cell carcinoma 82 ovarian cancer 75 glioma 68 leukemia 65 prostate cancer 64 glioblastoma 64 metastases 61 Li-Fraumeni syndrome 55 melanoma 54 pancreatic cancer 49 non-small cell lung cancer 49 osteosarcoma 43 lymphoma 41 lung carcinoma 41 retinoblastoma 38 epithelial ovarian cancer 34 neoplastic transformation 31 skin cancer 29 bladder cancer 29 gastric cancer 28 ATM 27 cervical cancer 25 acute myeloid leukemia 24 hepatitis B 24 dysplasia 23 Burkitt's lymphoma 23 more...

Symptom starvation 10 exhaustion 3 collapse 3 seizures 1 syncope 1 splenomegaly 1 cachexia 1 HSA 1 fatigue 1 dyspnea 1 skin damage 1 abdominal pain 1 vomiting 1 erythema 1 nausea 1 diarrhea 1 DNA marker 1 headache 1

Drug Dermatol 17 ROS 17 Adriamycin 15 lysine 12 caffeine 10 Paraffin 9 G418 9 Taxol 7 MDM 7 ABC 7 Gel 6 CPT-11 6 Mutagen 5 IFN-gamma 5 ADR 5 ETS 5 Arsenic trioxide 5 Asn 4 Meth 4 MRC 4 DNase I 4 NVP 4 PFT 4 TTC 4 Atropine 3 CSF 3 MAP 3 NADH 3 ADM 3 vitamin E 3 Oxaliplatin 3 Vorinostat 3 Radicicol 3 Docetaxel 3 Taxotere 2 TAC 2 Simvastatin 2 Flavopiridol 2 AGG 2 VCR 2 more...

Enzyme ERK 92 caspase-3 74 mitogen-activated protein kinase 73 proteasome 67 PARP 59 luciferase 58 protein kinase 45 cdc2 43 caspase-9 29 P-glycoprotein 26 chloramphenicol acetyltransferase 25 catalase 22 topoisomerase 20 beta-galactosidase 19 MEK 19 topoisomerase 17 focal adhesion kinase 17 caspase-8 17 thymidine kinase 16 glutathione S-transferase 14 RNA polymerase 13 AMP-activated protein kinase 13 ATPase 11 protein kinase C 11 ribonucleotide reductase 10 ribonucleotide reductase 10 AMPK 9 AMPK 9 reverse transcriptase 8 superoxide dismutase 8 APC 8 RNase 7 RNase 7 MDR 7 peroxidase 6 DNA polymerase 6 gamma-glutamyl transpeptidase 5 dihydrofolate reductase 5 endonuclease 5 caspase-1 5 more...

Compound DNA 1077 Dec 240 Clin 111 MDA 104 oxygen 69 arginine 48 His 47 MTT 41 alanine 38 serine 37 ATP 31 zinc 30 tyrosine 29 urea 26 methionine 26 Adriamycin 26 cysteine 24 lysine 20 glucose 19 CAT 17 CAT 17 sodium 17 CAT 17 ADR 17 anthracene 17 threonine 16 acetate 16 DDP 16 pyrene 14 leucine 14 nitric oxide 14 water 13 TNF 13 hydrogen 12 CHIP 12 phosphate 12 bromide 12 NOXA 12 GTP 11 pyrimidine 11 more...

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