Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:B6E4X6 (mutant p53)
 3,342 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
mutant p53 3342
p53 3017
p21 314
Mol 301
Sep 211
Bcl-2 143
MDM2 137
tumour suppressor 101
p73 99
p53 target 95
caspase-3 93
WAF1 87
bcl-2 87
ras 85
p63 75
PRIMA 71
proteasome 66
DNA-binding domain 57
PARP 55
Li-Fraumeni syndrome 53
more...
Disease
cancer 1685
tumor 1424
breast cancer 314
tumorigenesis 244
carcinoma 226
carcinogenesis 197
tumor progression 171
tumor growth 128
lung cancer 121
MCF 115
adenocarcinoma 99
colon cancer 90
hepatocellular carcinoma 86
colorectal cancer 82
squamous cell carcinoma 82
ovarian cancer 75
glioma 68
leukemia 65
glioblastoma 64
prostate cancer 64
more...
Symptom
starvation 10
exhaustion 3
collapse 3
seizures 1
syncope 1
splenomegaly 1
cachexia 1
HSA 1
fatigue 1
dyspnea 1
skin damage 1
abdominal pain 1
vomiting 1
erythema 1
nausea 1
diarrhea 1
DNA marker 1
headache 1
Drug
ROS 17
Dermatol 17
Adriamycin 15
lysine 12
caffeine 10
Paraffin 9
G418 9
MDM 7
Taxol 7
ABC 7
CPT-11 6
Gel 6
ADR 5
IFN-gamma 5
Mutagen 5
ETS 5
Arsenic trioxide 5
TTC 4
Asn 4
DNase I 4
more...
Enzyme
ERK 92
caspase-3 74
mitogen-activated protein kinase 73
proteasome 67
PARP 59
luciferase 58
protein kinase 45
cdc2 43
caspase-9 29
P-glycoprotein 26
chloramphenicol acetyltransferase 25
catalase 22
topoisomerase 20
MEK 19
beta-galactosidase 19
caspase-8 17
focal adhesion kinase 17
topoisomerase 17
thymidine kinase 16
glutathione S-transferase 14
more...
Compound
DNA 1077
Dec 240
Clin 111
MDA 104
oxygen 69
arginine 48
His 47
MTT 41
alanine 38
serine 37
ATP 31
zinc 30
tyrosine 29
methionine 26
urea 26
Adriamycin 26
cysteine 24
lysine 20
glucose 19
CAT 17
more...