Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:B0FTZ7 (catenin)
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Human Gene/Protein
CRISPLD1 10.7
serine/threonine kinase 32B 10.7
ZNF614 10.7
Armadillo repeat-containing protein 8 10.7
PCDHGA9 10.7
ACSS2 protein 10.7
EPB41 protein 10.7
SPIN2B 10.7
ARFGAP1 protein 10.7
CHRDL2 10.7
LOC100129940 10.7
FLYWCH1 10.7
protocadherin 11X 10.7
ubiquitin protein ligase E3 component n-recognin 2 10.7
IQ motif and ubiquitin domain containing 10.7
GNG8 10.7
collagen, type IV, alpha 6 10.7
baculoviral IAP repeat-containing 6 10.7
catenin 10.7
Breast carcinoma amplified sequence 2 10.7
Histidine triad nucleotide binding protein 2 10.7
TMED5 10.7
epithelial discoidin domain receptor 1 10.7
Hematopoietically expressed homeobox 10.7
EPHA10 protein 10.7
phosphorylase kinase, beta 10.7
transmembrane protein 198 10.7
CTNNBIP1 protein 10.7
Activation peptide 10.7
M-phase phosphoprotein 9 10.7
F-box protein 16 10.7
G protein-coupled receptor 177 10.7
suppression of tumorigenicity 7-like 10.7
TTPAL 10.7
FAM123A 10.7
Transmembrane protein 170B 10.7
schlafen family member 5 10.7
C2 domain-containing protein 3 10.7
WNT10B protein 10.7
HOMER-3 10.7
ARL10 10.7
NBPF7 10.7
PCDHB17 10.7
neucrin 10.7
P2Y purinoceptor 1 10.7
Glutathione S-transferase omega 2 10.7
protocadherin gamma subfamily A, 9 10.7
breast cancer metastasis-suppressor 1-like 10.7
LOC441204 10.7
C9orf140 10.7
TatD DNase domain containing 1 10.7
chondroitin sulfate N-acetylgalactosaminyltransferase 2 10.7
Transmembrane protein 9 10.7
FOXB2 10.7
Alpha-catulin 10.7
tetraspanin 12 10.3
copine 6 10.1
RNA binding motif, single stranded interacting protein 3 10.1
Transmembrane protein 88 10.1
TAX1BP3 10.1
P120CTN 10.1
Glypican-2 10.1
CTNNBIP1 10.0
zinc and ring finger 3 9.9
axin 2 9.8
alphaT-catenin 9.8
ARVCF 9.8
Axin2 9.7
Microtubule-actin crosslinking factor 1 9.7
KRM2 9.7
PDZ domain containing 3 9.7
Tetraspanin 12 9.7
Axin 1 9.7
SH3GL2 protein 9.7
PPPDE1 protein 9.7
wingless-type MMTV integration site family, member 10B 9.7
LIM-1 9.7
Phytanoyl-CoA 2-hydroxylase 9.7
PYGO2 protein 9.7
V-set and transmembrane domain containing 2A 9.7
more...
Disease
DUPC1 10.7
Papillary craniopharyngioma 9.7
Lizard skin 9.7
Uterine fibrosis 9.7
Brisket disease 9.1
hair follicle disorder 9.1
Basal cell carcinoma with matrical differentiation 9.1
pediatric liver cancer 8.7
Aberrant Crypt Foci 8.4
colon growth 8.1
Atypical polypoid adenomyoma 7.9
Fetal adenocarcinoma 7.9
Adrenal carcinoma 7.9
type B thymoma 7.9
neoplasm of uncertain malignant potential 7.8
PPCD3 7.7
Tubular adenoma 7.6
Renal tubular atrophy 7.6
SOST 7.5
Islet cell tumor 7.4
Cardiac fibroma 7.4
DSH 7.2
Dentinogenic ghost cell tumor 7.1
Intravascular fasciitis 7.1
FGD2 7.1
EMT 7.1
floppy baby syndrome 7.0
Fibrodysplasia ossificans progressiva 7.0
PanIN-1 7.0
Thyroid Carcinoma 6.9
Adenomatosis 6.9
PanIN-3 6.9
Nuchal-type fibroma 6.8
Peritoneal infection 6.8
skin hyperkeratosis 6.8
MDS-U 6.7
Aortic valve calcification 6.6
MKS3 6.6
Mesenteric fibromatosis 6.6
cholemia 6.6
Van Buchem disease 6.6
Endometrioid carcinoma 6.5
invasive lobular breast carcinoma 6.5
Hepatocarcinogenesis 6.5
Small Intestine 6.5
Leukemia stem cell 6.5
metastatic follicular thyroid cancer 6.5
desmoid 6.5
HRPT2 6.5
intestinal cancer 6.4
Goblet cell carcinoid 6.3
Desmoplastic fibroma 6.3
metastatic parathyroid carcinoma 6.3
cerebral ischemia/hypoxia 6.3
relapsed childhood ALL 6.2
Renal interstitial fibrosis 6.2
PanIN-2 6.2
MCC deficiency 6.1
Renal fibrosis 6.1
Solid pseudopapillary tumor 6.0
OSX 6.0
Macroprolactinomas 6.0
APC 6.0
osteochondropathy 6.0
Basal cell adenocarcinoma 6.0
Primary progressive multiple sclerosis 6.0
familial adenomatous polyposis 6.0
disuse osteoporosis 6.0
Peritoneal fibrosis 5.9
pseudoglioma 5.9
NPHP4 5.9
Osteosarcoma 5.9
Osteosarcoma 5.9
Dedifferentiated chondrosarcoma 5.9
age related bone loss 5.9
Peripheral ameloblastoma 5.9
Colon cancer 5.9
tumor initiation 5.8
HCA 5.8
PPCD 5.8
more...
Symptom
difficulty with urination 6.0
Lung hyperinflation 5.9
Scratch 5.3
delayed language development 4.3
Neuropathic pain 3.3
impaired motor coordination 3.1
Noise-induced hearing loss 3.1
ACHE 2.9
neurological disability 2.5
hyperoxia 2.2
loss of taste 2.2
Tenderness 2.2
abdominal fullness 2.0
functional recovery 2.0
hepatomegaly 1.8
HSA 1.8
pelvic pain 1.7
masculinization 1.7
memory loss 1.7
Decreased activity 1.7
skin damage 1.2
bone pain 1.1
despair 1.1
exhaustion 1.0
abdominal discomfort 1.0
starvation 0.9
muscle cramps 0.9
dry skin 0.7
thinning 0.7
respiratory distress 0.7
polydipsia 0.6
urinary frequency 0.6
nasal congestion 0.6
decreased appetite 0.5
hot flushes 0.4
hypertonia 0.4
cachexia 0.3
polyuria 0.1
acute stress 0.1
bloating 0.0
epigastric pain -0.0
twitching -0.3
blurred vision -0.3
spasticity -0.3
abdominal pain -0.4
rhinorrhea -0.4
collapse -0.5
wheezing -0.5
splenomegaly -0.5
cancer pain -0.9
distraction -0.9
arthralgia -1.1
cerebellar ataxia -1.1
seizures -1.1
diarrhea -1.2
pain -1.3
dystonia -1.3
chills -1.3
hepatosplenomegaly -1.4
low back pain -1.6
acidity -1.6
ataxia -1.6
hypotonia -1.8
nausea -1.8
hemoptysis -1.9
fatigue -1.9
myalgia -2.0
tinnitus -2.0
dyspnea -2.0
weakness -2.2
hypercapnia -2.2
regurgitation -2.3
chest pain -2.3
hypothermia -2.4
overweight -2.4
syncope -2.4
nausea and vomiting -2.5
vomiting -2.6
discomfort -2.7
cough -2.8
more...
Drug
Fexaramine 10.7
Peretinoin 8.4
Hymenialdisine 7.4
Alsterpaullone 7.1
Ganirelix 6.6
Argininosuccinate 6.6
Gonadorelin 6.3
Berberine chloride 6.0
Fidarestat 5.9
Fidarestat 5.9
Tolfenamic acid 5.3
Eprinomectin 5.1
Emodin 5.0
Pizotifen 5.0
Ontak 4.8
Ontak 4.8
Butaprost 4.8
Casodex 4.7
CDX 4.7
OctreoScan 4.7
Emodin 4.7
Radicicol 4.7
Activin 4.6
KGF 4.6
Zebularine 4.6
GEO 4.6
ID2 4.6
Calcium silicate 4.6
Marimastat 4.6
Cremophor RH40 4.6
Rebamipide 4.5
Ciglitazone 4.4
Lipitor 4.4
CDX 4.3
Dasatinib 4.3
Sorafenib 4.3
Batimastat 4.2
Batimastat 4.2
OMP 4.2
AMK 4.2
PTC 4.1
Miglustat 4.1
Myricetin 4.0
Cinacalcet 4.0
Diamminedichloroplatinum 4.0
Terlipressin 3.9
Terlipressin 3.9
Lipitor 3.9
Lipitor 3.9
Ketorolac tromethamine 3.9
Teriparatide 3.9
Romidepsin 3.9
uPA 3.9
Pirfenidone 3.8
Safflower 3.8
PCP 3.8
Rhubarb 3.7
Propidium 3.7
Oxaliplatin 3.7
Podophyllotoxin 3.6
Clofarabine 3.6
Vioxx 3.6
Trabectedin 3.5
Vinpocetine 3.5
Epigallocatechin 3.5
Erlotinib 3.5
Span 60 3.4
NVP 3.4
Atovaquone 3.3
Gefitinib 3.3
L-Asparaginase 3.3
ETS 3.3
Fulvestrant 3.3
Imatinib 3.3
Raloxifene 3.2
ROS 3.2
Cetrorelix 3.1
CTX 3.1
CTX 3.1
Doyle 3.1
more...
Enzyme
GSK 7.9
mannosyl-oligosaccharide glucosidase 7.1
N-acetylglucosaminyltransferase III 6.7
EC 5.3.99.2 6.6
STK4 6.3
site-1 protease 5.9
histone-lysine N-methyltransferase 5.7
D-dopachrome tautomerase 5.7
matrix metalloproteinase 10 5.6
ALDH 5.4
APC 5.4
acylglycerol kinase 5.0
N-acetylglucosaminyltransferase V 5.0
site-1 protease 4.9
ribose-5-phosphate isomerase 4.9
luciferase 4.8
lysine acetyltransferase 4.8
sulfiredoxin 4.7
histone demethylase 4.7
Tpt1 4.7
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.7
nicotinamide phosphoribosyltransferase 4.5
phosphoinositide 3-kinase 4.5
arachidonate 5-lipoxygenase 4.5
STK11 4.4
protein kinase 4.4
HK2 4.4
glutamine synthetase 4.4
CDH 4.4
focal adhesion kinase 4.3
matrix metalloproteinase 14 4.3
protein phosphatase 2A 4.3
PDK1 4.2
MMP 4.2
matrix metalloproteinase 9 4.1
adenine deaminase 4.1
cathepsin K 4.0
BAT 4.0
mitogen-activated protein kinase 4.0
Protein 2 4.0
ERK 3.9
lysophospholipase D 3.9
rhomboid protease 3.9
MEK 3.9
caspase-3 3.9
phosphofructokinase 1 3.9
PARP 3.9
inositol 3-kinase 3.9
FPS 3.9
matrix metalloproteinase 2 3.9
AMPK 3.8
LDT 3.8
caspase-4 3.8
glucosylceramide synthase 3.8
phosphatidylinositol 3-kinase 3.8
guanylate kinase 3.8
aldehyde dehydrogenase 3.8
aldehyde dehydrogenase 3.8
aldehyde dehydrogenase 3.8
O-GlcNAc transferase 3.8
PCP 3.8
15-hydroxyprostaglandin dehydrogenase 3.8
caspase-9 3.7
hatching enzyme 3.7
CNPase 3.7
caspase-4 3.6
aldehyde dehydrogenase 3.6
AMP-activated protein kinase 3.6
PHD 3.6
HPI 3.5
alkaline phosphatase 3.4
inosine triphosphatase 3.4
protein disulfide-isomerase 3.4
CD10 3.4
histone acetyltransferase 3.4
proteasome 3.4
MMP-3 3.3
mu-calpain 3.3
CYP46A1 3.3
aldehyde dehydrogenase 3.3
more...
Compound
Erioflorin 10.7
C21H14ClN3O4S 10.7
Fexaramine 10.7
Tetraethyleneglycol dimethacrylate 9.7
C18H18N2O2 9.7
Pyrvinium 9.3
Telocinobufagin 8.7
2-acetyl-1,3-cyclopentanedione 8.7
C17H18O5 8.7
Lecanoric acid 8.4
Maclurin 8.1
5-Methoxytryptophan 8.1
Physodic acid 7.9
6-ECDCA 7.9
Cornin 7.9
Linoelaidic acid 7.9
Ovatodiolide 7.8
Azoxymethane 7.8
Methyl vanillate 7.7
Lithium chloride 7.7
Girinimbine 7.6
Calotropin 7.6
Xanthatin 7.5
Ethyl ferulate 7.4
Calotropin 7.4
Cyclovirobuxine D 7.4
Ethyl linoleate 7.4
Triptonide 7.3
Calotropin 7.3
Chebulagic acid 7.1
Bruceine D 7.1
Jatrophone 7.1
Chebulagic acid 7.1
Sulfuretin 7.1
Xanthatin 7.1
Glycogen synthase 7.0
Justicidin B 7.0
2,4-pyrimidinediamine 7.0
Methacycline 7.0
4-Methylcatechol 6.9
Aeroplysinin-1 6.9
Salinomycin 6.9
Vimentin 6.8
Isochlorogenic acid 6.7
Nonactin 6.6
Isoquercitrin 6.5
Amarogentin 6.5
Raddeanin A 6.5
methyl 3,4-dihydroxybenzoate 6.5
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 6.4
Chebulinic acid 6.4
Pinosylvin 6.3
Pinosylvin 6.3
Ailanthone 6.3
Limonin 6.3
TRU 6.3
Limonin 6.3
Gedunin 6.3
Gonadorelin 6.3
Limonin 6.3
Lycorine 6.2
Berbamine 6.2
Saikosaponin A 6.2
Geraniin 6.2
Atranorin 6.1
Psoralidin 6.1
Hymenialdisine 6.1
4-Thiouridine 6.0
Lupeol 6.0
Lanatoside C 6.0
Ginkgetin 6.0
Ergosterol peroxide 6.0
Notoginsenoside R1 6.0
KI3 5.9
Ciclopirox olamine 5.9
Eupatilin 5.9
Lumichrome 5.9
FMI 5.8
Alizarin Red S 5.8
Morusin 5.8
more...