Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:B0FTZ7 (
catenin
)
18,795
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
catenin
18795
E-cadherin
2267
Mol
1869
Sep
1048
cadherin
1018
cyclin D1
949
GSK
938
p53
773
AKT
725
N-cadherin
722
PI3K
655
TCF
639
c-Myc
626
beta-catenin
579
osteogenic
570
vimentin
565
CTNNB1
492
collagen
451
caspase-3
401
APC
389
ERK
387
c-myc
378
mTOR
377
MAPK
367
p120
335
adenomatous polyposis coli
313
alkaline phosphatase
309
Bcl-2
304
Axin
289
CD44
282
TCF4
272
TNF
260
Dickkopf-1
253
DKK1
247
insulin
246
cytokine
243
alpha-catenin
242
p21
239
fibronectin
236
lymphoid
233
vascular endothelial growth factor
232
Axin2
229
EMT
227
Rho
215
LRP6
211
EGFR
208
matrix metalloproteinase
208
STAT3
204
ERK1
200
Cyclin D1
199
VEGF
184
Ki-67
184
vascular endothelium
183
PTEN
183
GSK3
182
p38
181
osteocalcin
181
MMP-9
178
proteasome
174
LRP5
171
IL-6
170
ubiquitin
169
SMA
169
JNK
168
tyrosine kinase
168
osteosarcoma
167
CD133
167
ZO-1
167
survivin
167
histone
165
plakoglobin
165
epidermal growth factor receptor
164
Vimentin
163
sclerostin
163
smooth muscle actin
162
RhoA
160
tumor necrosis factor
158
UTR
158
LEF1
156
BRAF
156
proliferating cell nuclear antigen
155
RANKL
148
Slug
147
gut
144
MMP-2
144
COX-2
141
CCK
139
KRAS
135
estrogen receptor
134
vinculin
132
ZEB1
129
occludin
128
MEK
127
p120 catenin
127
gamma-catenin
124
Nanog
121
TNM
118
MYC
116
YAP
115
STAT
115
MMP9
114
hedgehog
114
sonic hedgehog
110
phosphatase
109
ATP
108
CD34
107
frizzled
107
endoplasmic reticulum
107
PARP
106
cage
104
LEF-1
104
osteoprotegerin
103
Oct4
103
p65
103
transcription factor 7-like 2
101
ROS
101
extracellular signal-regulated kinase
100
protein kinase B
100
GTPase
99
cyclin
99
bone morphogenetic protein
98
androgen receptor
98
AXIN2
97
kit
97
ALP
96
c-Jun
96
Wnt4
95
peroxisome proliferator-activated receptor
95
tumour suppressor
93
Glycogen synthase
92
Cadherin
92
RUNX2
92
phosphatidylinositol 3-kinase
92
glycogen synthase kinase 3
91
p27
90
CCND1
90
Wnt receptor
88
cell adhesion molecule
87
IL-8
87
lipopolysaccharide
87
scratch
86
Smad2
86
Sclerostin
85
E3 ubiquitin ligase
85
cyclooxygenase-2
85
FAK
85
MMP2
84
focal adhesion kinase
84
threonine
83
low-density lipoprotein receptor
82
c-MYC
80
OCT4
79
p16
79
phosphoinositide 3-kinase
79
ATPase
79
osteopontin
78
MMP7
78
SNAIL
78
TCF7L2
76
AP-1
75
more...
Disease
cancer
5391
tumor
4658
tumorigenesis
1486
colorectal cancer
1225
breast cancer
905
hepatocellular carcinoma
884
tumor growth
857
carcinogenesis
840
carcinoma
824
tumor progression
752
colon cancer
712
adenocarcinoma
463
lung cancer
425
gastric cancer
415
APC
390
metastases
387
osteoporosis
339
prostate cancer
321
glioma
296
squamous cell carcinoma
294
melanoma
293
liver cancer
250
non-small cell lung cancer
239
diabetes
236
adenoma
233
EMT
227
leukemia
217
MCF
214
osteosarcoma
197
liver cancer
193
pancreatic cancer
193
ovarian cancer
188
obesity
181
glioblastoma
175
Alzheimer's disease
173
Hepatocellular carcinoma
165
familial adenomatous polyposis
161
aggressiveness
152
dysplasia
150
cervical cancer
128
osteoarthritis
127
bladder cancer
125
colitis
119
acute myeloid leukemia
119
tumor initiation
118
ischemia
102
renal cell carcinoma
100
epithelial ovarian cancer
94
primary tumor
91
desmoid
89
Parkinson's disease
88
endometrial cancer
84
chronic myeloid leukemia
83
multiple myeloma
81
Blocking
78
WT1
78
Osteosarcoma
76
Osteosarcoma
76
neuroblastoma
75
glioblastoma multiforme
74
coronary artery disease
71
depression
69
hypertension
69
B-cell lymphoma
69
type 2 diabetes
67
stroke
67
renal disease
66
pulmonary fibrosis
66
liver fibrosis
65
mammary tumor
64
brain tumor
63
hepatitis B
59
sarcoma
59
AS1
59
AGS
58
diabetic nephropathy
57
atherosclerosis
57
DDP
57
lymphoma
57
cirrhosis
56
cardiovascular disease
55
autism
55
SCID
55
heart failure
55
inflammatory bowel disease
55
bone disease
54
uterus
53
aggression
52
asthma
52
lung carcinoma
52
idiopathic pulmonary fibrosis
51
thyroid cancer
50
medulloblastoma
49
fibromatosis
49
NOD
48
polyposis
48
hepatoblastoma
48
rheumatoid arthritis
48
skin cancer
48
schizophrenia
46
cardiomyopathy
46
HCC
44
hyperglycemia
44
papillary thyroid cancer
43
esophageal cancer
41
proteinuria
41
plaque
41
myocardial infarction
41
Glioblastoma
41
Colon cancer
40
HIV
39
esophageal cancer
39
virus infection
39
ulcerative colitis
38
neoplastic transformation
37
endometriosis
37
Fibrodysplasia ossificans progressiva
37
retinoblastoma
35
Melanoma
35
ABL
35
metastatic breast cancer
35
HGF
35
cerebral ischemia
34
liver disease
34
metabolic syndrome
33
liver metastases
33
cognitive impairment
33
tumor angiogenesis
33
oral cancer
33
arthritis
32
GSH
32
adrenocortical carcinoma
32
lung disease
31
infectious diseases
31
intestinal cancer
31
HCA
31
bipolar disorder
31
hepatitis C
31
chronic obstructive pulmonary disease
31
basal cell carcinoma
30
metastatic melanoma
30
SOST
30
PCP
30
infertility
30
Hippel
29
CTX
29
sepsis
29
sepsis
29
Epstein
29
periodontitis
28
Leukemia
28
polycystic kidney
27
heart disease
27
ATM
27
leukemogenesis
27
DSS
27
DSS
27
renal failure
27
craniopharyngioma
26
blindness
25
more...
Symptom
pain
64
functional recovery
31
starvation
28
seizures
22
respiratory distress
19
exhaustion
16
diarrhea
15
hyperoxia
14
abdominal pain
14
hepatomegaly
12
collapse
12
thinning
11
Scratch
9
pelvic pain
8
anesthesia
8
fatigue
8
Neuropathic pain
8
memory loss
7
HSA
6
masculinization
5
weakness
5
dyspnea
4
nausea
4
bone pain
4
splenomegaly
4
cachexia
4
neurological disability
3
acute stress
3
distraction
3
overweight
3
spasticity
3
acidity
3
ataxia
3
vomiting
3
cough
2
skin damage
2
epigastric pain
2
despair
2
discomfort
2
discomfort
2
analgesia
2
wheezing
2
arthralgia
2
dystonia
2
low back pain
2
hypothermia
2
polydipsia
2
chest pain
2
polyuria
2
abdominal discomfort
2
impaired motor coordination
1
bloating
1
Decreased activity
1
blurred vision
1
anorexia
1
Lung hyperinflation
1
Noise-induced hearing loss
1
loss of taste
1
regurgitation
1
dry skin
1
difficulty with urination
1
rhinorrhea
1
hypercapnia
1
hot flushes
1
urinary frequency
1
cerebellar ataxia
1
syncope
1
muscle cramps
1
hypertonia
1
chills
1
hepatosplenomegaly
1
myalgia
1
decreased appetite
1
hypotonia
1
angina
1
twitching
1
cancer pain
1
tinnitus
1
abdominal fullness
1
nasal congestion
1
Tenderness
1
headache
1
delayed language development
1
hemoptysis
1
nausea and vomiting
1
tremor
1
ACHE
1
Drug
Dermatol
118
lysine
106
ROS
101
Monit
49
PCP
30
CTX
29
CTX
29
CTX
29
Activin
25
PTH
22
GEO
22
IL-2
20
MAP
20
uPA
18
PTC
18
ABC
17
Sorafenib
17
Cardiovasc
16
CAM
16
Retinoic acid
16
Leaf
15
ETS
15
Imatinib
14
CSF
13
ICI
12
p75
10
Adriamycin
10
ADR
9
Emodin
9
Emodin
9
Simvastatin
8
vitamin E
8
Ethanol
8
MRC
8
Dasatinib
7
Gefitinib
7
Oxaliplatin
7
Propofol
7
Asthma
7
KGF
7
Alliance
7
Taxol
6
NVP
6
Portal
6
TAT
6
Indomethacin
6
ascorbate
5
OMP
5
Herceptin
5
Erlotinib
5
Paraffin
5
Angiotensin II
5
Heme
5
IL-11
5
Spectrum
5
ADM
5
Doxycycline
5
EPA
5
Vitamin A
4
Glutathione
4
Albumin
4
Asn
4
Parkin
4
Itraconazole
4
Parkin
4
Glucagon
4
Gelatin
4
Raloxifene
4
Fraction
4
Nephron
4
ID2
4
caffeine
4
CDX
4
Nephron
4
CDX
4
Rosiglitazone
4
EE2
4
Vitamin E
4
Epigallocatechin
3
Docetaxel
3
VCR
3
Myricetin
3
VCR
3
DHT
3
Irinotecan
3
ACT
3
Alanine
3
Bortezomib
3
Estrogens
3
Growth hormone
3
DHT
3
Casodex
3
Lovastatin
3
Growth hormone
3
TTC
3
FAD
3
ROC
3
Teriparatide
3
Dial
3
Gel
3
Lenalidomide
3
AMC
3
Bifidobacterium
3
CCL
3
Fulvestrant
2
DM1
2
Urokinase
2
MDS
2
RFP
2
lactose
2
Gleevec
2
DEX
2
Tolfenamic acid
2
G418
2
CoCl2
2
CoCl2
2
Denosumab
2
Cinacalcet
2
Ginger
2
Propidium
2
TAK
2
Tacrolimus
2
Rebamipide
2
Diamminedichloroplatinum
2
Ouabain
2
ALA
2
Liraglutide
2
nitroglycerin
2
Cilostazol
2
Spectrum
2
Xanthium
2
PDL
2
Cetuximab
2
CPT-11
2
Captopril
2
Fluorescein
2
Doyle
2
Ranitidine
2
Nitric Oxide
2
TAC
2
Glide
2
Pirfenidone
2
IFN-gamma
2
Vitamin K
2
Troglitazone
2
Aliskiren
1
Norplant
1
Amifostine
1
Theophylline
1
CTC
1
CPZ
1
Ketorolac tromethamine
1
Podophyllotoxin
1
Ketorolac
1
Atovaquone
1
Retinoic Acid
1
Misoprostol
1
Ontak
1
Cremophor RH40
1
Pizotifen
1
more...
Enzyme
protein kinase
1028
GSK
944
mitogen-activated protein kinase
904
ERK
865
luciferase
639
focal adhesion kinase
520
APC
394
caspase-3
318
alkaline phosphatase
309
proteasome
175
MEK
162
PARP
118
protein kinase C
116
phosphatidylinositol 3-kinase
92
AMP-activated protein kinase
91
ATPase
86
phosphoinositide 3-kinase
79
superoxide dismutase
70
calcineurin
65
glutamine synthetase
63
CD10
61
caspase-9
58
AMPK
55
AMPK
53
ACS
50
reverse transcriptase
45
MMP
45
catalase
42
P-glycoprotein
41
glutathione S-transferase
41
cdc2
39
collagenase
38
aldehyde dehydrogenase
37
renin
37
caspase-8
37
aldehyde dehydrogenase
36
aldehyde dehydrogenase
36
aldehyde dehydrogenase
36
aldehyde dehydrogenase
36
protein phosphatase 2A
34
lactate dehydrogenase
32
RNA polymerase
32
alanine aminotransferase
31
PCP
30
tyrosinase
29
urokinase-type plasminogen activator
28
DNA methyltransferase
27
thrombin
25
PDK1
25
aspartate aminotransferase
25
demethylase
23
NADPH oxidase
23
NADPH oxidase
23
matrix metalloproteinase 9
22
ALDH
22
peroxidase
22
phospholipase C
22
MMP-3
20
matrix metalloproteinase 2
20
CaMKII
19
trypsin
19
tyrosine hydroxylase
18
glutathione peroxidase
18
cathepsin K
18
histone acetyltransferase
17
phosphodiesterase
17
transcriptase
16
IKK
16
histone demethylase
15
MAP
15
lipoprotein lipase
13
PKG
13
myosin light chain kinase
13
furin
12
topoisomerase
12
topoisomerase
12
MDR
11
caspase-1
10
pyruvate kinase
10
lysozyme
10
acetyl-CoA carboxylase
10
acid phosphatase
10
arginase
10
firefly luciferase
9
NQO1
9
CAD
8
NO synthase
8
CAD
8
elastase
8
CAD
8
SPC
8
PDE
8
BAT
8
tissue plasminogen activator
7
transglutaminase
7
HK2
7
glyceraldehyde-3-phosphate dehydrogenase
7
prostate-specific antigen
7
NOS
7
TAT
7
complex I
7
CDH
7
AST
7
MPP
7
guanylate cyclase
6
lysyl oxidase
6
N-acetylglucosaminyltransferase III
6
STK11
6
neuraminidase
6
PHD
6
CYP3A4
6
kinesin
6
LPL
6
acetylcholinesterase
6
endonuclease
6
MEKK1
6
diamine oxidase
5
RNase
5
TdT
5
15-hydroxyprostaglandin dehydrogenase
5
carbonic anhydrase
5
peroxiredoxin
5
glucose-6-phosphatase
5
heme oxygenase
5
isocitrate dehydrogenase
5
isocitrate dehydrogenase
5
DCF
5
alcohol dehydrogenase
5
nicotinamide phosphoribosyltransferase
5
succinate dehydrogenase
5
triphosphatase
5
creatine kinase
5
sialidase
5
RNase
5
phospholipase A2
4
phosphorylase
4
monoamine oxidase
4
subtilisin
4
lipase
4
xanthine oxidase
4
gamma-glutamyl transpeptidase
4
ornithine decarboxylase
4
caspase-2
4
prolyl hydroxylase
4
adenylate cyclase
4
pyruvate dehydrogenase
4
DNA ligase
4
cathepsin D
4
DNA ligase
4
O-GlcNAc transferase
4
ATP synthase
4
glucocerebrosidase
4
sucrase
4
caspase-7
4
HSD
4
caspase-7
4
caspase-2
4
kallikrein
4
CNPase
4
m-calpain
4
more...
Compound
Dec
1147
DNA
899
calcium
475
Clin
433
oxygen
397
tyrosine
374
MTT
360
glucose
348
MDA
271
TNF
260
serine
212
sodium
177
Vimentin
163
water
162
phosphate
144
sulfate
138
threonine
135
lysine
130
retinoic acid
126
MEK
125
leucine
124
TNM
118
ATP
109
methionine
103
ALP
96
cAMP
94
Glycogen synthase
92
bromide
83
cysteine
78
vitamin D
74
arginine
68
DDP
64
zinc
64
Curcumin
62
ethanol
57
hydrogen
56
ADP
55
nitric oxide
55
titanium
54
ASA
54
ADP
52
ADP
52
creatinine
50
ACS
50
ACS
50
Lithium
48
alanine
46
acetate
46
PGE2
44
urea
43
BCR
42
PGE
41
Collagen
40
iron
39
nitrogen
37
iodine
36
5-FU
36
Alizarin
35
AMP
35
GSH
35
ABL
35
GSH
35
Resveratrol
35
Leucine
35
glutamate
34
Pac
34
Lithium chloride
32
Vitamin D
31
PCP
30
galactose
30
salt
30
dUTP
29
H2O2
29
Mato
29
CTX
29
DSS
28
PEG
27
NAD
27
nicotinamide
26
aldosterone
26
Insulin
26
GTP
25
cGMP
24
Asp
24
ADP-ribose
24
glutamine
23
His
23
Estrogen
23
Triton X-100
22
Estrogen
22
1,2-dimethylhydrazine
22
Adriamycin
22
Metformin
21
NH2
21
selenium
21
N-acetylcysteine
21
Metformin
21
cadmium
21
THP
21
MTS
21
THP
21
potassium
21
tryptophan
20
NAD
20
CAM
20
proline
20
COX
20
Neuronal
20
Phe
20
ADR
20
DMSO
19
SDS
19
Tyrosine
19
Thyroid
19
GlcNAc
19
Berberine
18
MDR
18
SCC
18
Androgen
18
MPTP
17
Casein
17
POP
17
Quercetin
17
Glycogen
17
Ang II
16
Hematoxylin
16
Ubiquitin
16
hyaluronic acid
16
Salinomycin
16
Cardiol
16
MAP
15
PEG
15
CCl4
15
Histone
15
Temozolomide
15
Phosphatidylinositol
15
Cereb
15
tryptophan
14
Melatonin
14
NMDA
14
FAP
14
phosphorus
14
tryptophan
14
Celecoxib
14
Serine
14
FAP
14
anthracene
14
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
14
tryptophan
14
Alizarin Red S
14
Dexamethasone
13
H2S
13
adenosylmethionine
13
pyrimidine
13
strontium
13
5-HT
13
STZ
13
DAPT
13
Rapamycin
12
pyrimidine
12
more...