Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:A9QXG9 (bcl-2)
7,497 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
bcl-2 7497
p53 1895
bax 1524
Bcl-2 1309
caspase-3 962
Sep 512
c-myc 454
Mol 397
Ki-67 382
Fas 332
lymphoid 332
proto-oncogene 300
p21 299
CD34 246
Bcl-X 234
cytochrome c 223
caspase-9 212
bcl-x 209
cytokine 198
proliferating cell nuclear antigen 189
Bax protein 175
cyclin D1 174
CD10 160
vimentin 159
CD20 144
survivin 142
PARP 130
anti-apoptotic protein 126
non-Hodgkin's lymphoma 125
MIB 124
superoxide dismutase 122
annexin V 119
tumor necrosis factor 119
erbB-2 115
p27 114
estrogen receptor 114
Bcl-6 111
caspase-8 111
nodal 110
TNF 108
CD95 103
IgG3 97
IL-6 97
CD99 96
TdT 96
ras 95
CD5 93
CD4 93
c-fos 92
cyclin D 88
cytokeratin 87
mutant p53 87
collagen 86
desmin 84
IL-2 83
vascular endothelial growth factor 80
APO-1 80
IgH 78
Fas ligand 78
GSH 76
thymus 76
catalase 75
CD8 73
epidermal growth factor receptor 70
membrane protein 67
TNF-alpha 66
cyclin 66
VEGF 65
progesterone receptor 64
c-kit 64
p38 63
p16 61
JNK 60
glutathione peroxidase 60
CD23 60
inhibitor of apoptosis 59
endoplasmic reticulum 59
MAPK 58
poly(ADP-ribose) polymerase 58
p65 58
more...
Disease
tumor 1702
cancer 1618
lymphoma 606
carcinoma 474
leukemia 344
breast cancer 330
follicular lymphoma 259
B-cell lymphoma 237
Hodgkin's disease 226
carcinogenesis 214
tumorigenesis 212
prostate cancer 187
Epstein 173
metastases 171
MCF 169
tumor growth 156
non-Hodgkin's lymphoma 146
ischemia 140
adenocarcinoma 135
B-cell lymphomas 132
chronic lymphocytic leukemia 124
squamous cell carcinoma 124
melanoma 120
lung cancer 114
acute myeloid leukemia 112
hepatocellular carcinoma 108
tumor progression 107
chronic lymphocytic leukemia 101
Leukemia 95
Burkitt's lymphoma 89
multiple myeloma 85
GSH 76
neuroblastoma 75
glioma 71
dysplasia 67
colorectal cancer 64
acute lymphoblastic leukemia 63
gastric cancer 62
colon cancer 62
non-small cell lung cancer 60
Alzheimer's disease 59
cerebral ischemia 59
adenoma 59
diabetes 58
retinoblastoma 58
HIV 58
stroke 56
mucosa-associated lymphoid tissue 54
acute promyelocytic leukemia 53
lung carcinoma 52
immunodeficiency 51
sarcoma 50
B-cell chronic lymphocytic leukemia 46
aggressiveness 45
Parkinson's disease 45
virus infection 44
cervical cancer 44
mantle cell lymphoma 44
AIDS 43
ovarian cancer 42
synovial sarcoma 41
lymphoproliferative disorders 40
EMA 39
EBV infection 39
chronic myeloid leukemia 38
suicide 37
bladder cancer 36
Solitary fibrous tumor 36
epithelial ovarian cancer 35
autoimmune disease 35
endometrial cancer 35
primary tumor 33
neoplastic transformation 33
basal cell carcinoma 32
pancreatic cancer 32
minimal residual disease 32
lymphadenopathy 32
systemic lupus erythematosus 32
myeloid leukemia 31
glioblastoma 30
more...
Symptom
starvation 27
collapse 24
pain 17
splenomegaly 15
functional recovery 13
seizures 10
anesthesia 9
abdominal pain 8
headache 8
erythema 6
cough 5
hypothermia 5
weakness 5
fatigue 4
flank pain 4
hepatosplenomegaly 4
chest pain 4
cachexia 4
exhaustion 4
nausea 3
dyspnea 3
hyperoxia 3
acute stress 3
arthralgia 3
vomiting 3
back pain 3
shortness of breath 3
dry eye 3
ENT 2
fever of unknown origin 2
abdominal discomfort 2
myoclonus 2
thinning 2
abdominal fullness 2
skin damage 2
epigastric pain 2
stridor 2
hemoptysis 2
ataxia 2
autodigestion 2
hepatomegaly 2
diarrhea 2
neurological disability 2
Scratch 1
dysarthria 1
dysuria 1
pallor 1
masculinization 1
memory loss 1
pelvic pain 1
facial droop 1
tenesmus 1
heartburn 1
anosmia 1
cerebellar ataxia 1
cancer pain 1
flushing 1
Anoxia 1
tingling 1
polydipsia 1
leg edema 1
hemiplegia 1
precordial pain 1
respiratory distress 1
productive cough 1
myalgia 1
paresis 1
polyuria 1
hoarseness 1
chromosome marker 1
agitation 1
numbness 1
constipation 1
Neuropathic pain 1
menopausal symptoms 1
sore throat 1
tremor 1
Neurologic symptoms 1
blurred vision 1
disturbed balance 1
more...
Drug
IL-2 83
Dermatol 64
ROS 52
Paraffin 37
CSF 37
IFN-gamma 32
Taxol 23
ADR 23
Rituximab 22
MAP 22
Docetaxel 17
Adriamycin 16
Genasense 15
CED 14
Cardiovasc 14
vitamin E 13
Ginseng 10
CAM 10
G-CSF 10
ADM 10
BH4 10
Gel 10
Retinoic acid 9
ABC 9
p75 9
ascorbate 8
lysine 8
EE2 8
Taxotere 8
Arsenic trioxide 8
CPT-11 7
MDS 7
Monit 7
NADH 7
DNase I 6
CTX 6
Bortezomib 6
Indomethacin 6
Mutagen 5
TTC 5
Glutathione 5
Campath 5
Campath 5
PTH 5
Ethanol 5
Fludarabine 5
Heme 4
G418 4
AMC 4
ZnO 4
Zoledronic acid 4
Herceptin 4
DEX 4
MDM 4
VCR 4
Flavopiridol 4
Gefitinib 4
ICI 4
Growth hormone 4
Growth hormone 4
Etoposide 4
VCR 4
DHT 3
BLyS 3
Clopidogrel 3
DHT 3
Zoledronic acid 3
Rasagiline 3
Sorafenib 3
Angiotensin II 3
AraC 3
NBT 3
MRC 3
TAC 3
AZT 3
AZT 3
ALA 3
Vitamin K2 2
Trabectedin 2
uPA 2
more...
Enzyme
caspase-3 812
mitogen-activated protein kinase 197
ERK 175
caspase-9 169
CD10 160
superoxide dismutase 154
PARP 143
protein kinase 120
catalase 92
protein kinase C 87
caspase-8 77
caspase-1 70
reverse transcriptase 66
TdT 62
peroxidase 60
glutathione peroxidase 60
lactate dehydrogenase 56
cdc2 53
focal adhesion kinase 49
P-glycoprotein 46
topoisomerase 46
topoisomerase 40
luciferase 34
MEK 33
alanine aminotransferase 30
aspartate aminotransferase 29
glutathione S-transferase 29
cathepsin D 26
RNase 25
RNase 25
RNA polymerase 24
proteasome 23
phosphatidylinositol 3-kinase 22
prostate-specific antigen 22
alkaline phosphatase 22
transcriptase 21
caspase-7 21
calcineurin 21
caspase-2 20
caspase-7 19
caspase-2 17
endonuclease 17
AST 15
APC 14
granzyme B 14
ATPase 14
glyceraldehyde-3-phosphate dehydrogenase 14
transglutaminase 14
thymidylate synthase 14
NO synthase 13
beta-galactosidase 13
tyrosine hydroxylase 12
MDR 12
acetylcholinesterase 11
MAP 11
glutathione reductase 11
complex I 11
lysozyme 9
GSK 9
collagenase 9
thymidine phosphorylase 8
cathepsin B 8
AMP-activated protein kinase 8
CD13 8
phosphoinositide 3-kinase 8
MPP 8
phospholipase C 8
creatine kinase 8
DNA polymerase 7
chloramphenicol acetyltransferase 7
caspase-6 7
dihydrofolate reductase 7
thymidine kinase 7
trypsin 7
phosphodiesterase 7
NADPH oxidase 6
glyceraldehyde-3-phosphate dehydrogenase 6
urokinase-type plasminogen activator 6
renin 6
caspase-6 6
more...
Compound
DNA 1456
Dec 556
Clin 393
oxygen 342
MTT 236
dUTP 173
calcium 157
retinoic acid 113
TNF 108
glucose 105
MDA 89
nitric oxide 88
iodine 80
GSH 79
GSH 79
hydrogen 74
sodium 73
bromide 69
water 67
tyrosine 65
acetate 62
glutamate 55
cysteine 51
ATP 48
H2O2 45
serine 39
ethanol 36
cAMP 34
Asp 34
ADR 34
ADP-ribose 33
N-acetylcysteine 32
zinc 32
Adriamycin 27
nitrogen 27
MEK 27
boron 27
Neuronal 27
alanine 27
phosphate 26
ADP 25
TNM 25
acridine 24
VP-16 24
arginine 24
iron 23
AMP 22
Curcumin 22
Estrogen 22
DDP 22
formaldehyde 21
methionine 21
PMA 21
ADP 20
ADP 20
potassium 19
silver 19
Hoechst 33342 19
PMA 18
NH2 18
Estrogen 18
vitamin D 17
threonine 17
CAT 17
CAT 17
copper 17
CAT 17
PEG 16
creatinine 15
galactose 15
salt 15
Androgen 15
DMSO 15
Pac 15
Ara-C 14
selenium 14
sulfate 14
5-FU 13
leucine 13
nickel 13
more...