Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:A9QXG9 (
bcl-2
)
7,497
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
bcl-2
7497
p53
1895
bax
1524
Bcl-2
1309
caspase-3
962
Sep
512
c-myc
454
Mol
397
Ki-67
382
Fas
332
lymphoid
332
proto-oncogene
300
p21
299
CD34
246
Bcl-X
234
cytochrome c
223
caspase-9
212
bcl-x
209
cytokine
198
proliferating cell nuclear antigen
189
Bax protein
175
cyclin D1
174
CD10
160
vimentin
159
CD20
144
survivin
142
PARP
130
anti-apoptotic protein
126
non-Hodgkin's lymphoma
125
MIB
124
superoxide dismutase
122
annexin V
119
tumor necrosis factor
119
erbB-2
115
p27
114
estrogen receptor
114
Bcl-6
111
caspase-8
111
nodal
110
TNF
108
CD95
103
IgG3
97
IL-6
97
CD99
96
TdT
96
ras
95
CD5
93
CD4
93
c-fos
92
cyclin D
88
cytokeratin
87
mutant p53
87
collagen
86
desmin
84
IL-2
83
vascular endothelial growth factor
80
APO-1
80
IgH
78
Fas ligand
78
GSH
76
thymus
76
catalase
75
CD8
73
epidermal growth factor receptor
70
membrane protein
67
TNF-alpha
66
cyclin
66
VEGF
65
progesterone receptor
64
c-kit
64
p38
63
p16
61
JNK
60
glutathione peroxidase
60
CD23
60
inhibitor of apoptosis
59
endoplasmic reticulum
59
MAPK
58
poly(ADP-ribose) polymerase
58
p65
58
more...
Disease
tumor
1702
cancer
1618
lymphoma
606
carcinoma
474
leukemia
344
breast cancer
330
follicular lymphoma
259
B-cell lymphoma
237
Hodgkin's disease
226
carcinogenesis
214
tumorigenesis
212
prostate cancer
187
Epstein
173
metastases
171
MCF
169
tumor growth
156
non-Hodgkin's lymphoma
146
ischemia
140
adenocarcinoma
135
B-cell lymphomas
132
chronic lymphocytic leukemia
124
squamous cell carcinoma
124
melanoma
120
lung cancer
114
acute myeloid leukemia
112
hepatocellular carcinoma
108
tumor progression
107
chronic lymphocytic leukemia
101
Leukemia
95
Burkitt's lymphoma
89
multiple myeloma
85
GSH
76
neuroblastoma
75
glioma
71
dysplasia
67
colorectal cancer
64
acute lymphoblastic leukemia
63
gastric cancer
62
colon cancer
62
non-small cell lung cancer
60
Alzheimer's disease
59
cerebral ischemia
59
adenoma
59
diabetes
58
retinoblastoma
58
HIV
58
stroke
56
mucosa-associated lymphoid tissue
54
acute promyelocytic leukemia
53
lung carcinoma
52
immunodeficiency
51
sarcoma
50
B-cell chronic lymphocytic leukemia
46
aggressiveness
45
Parkinson's disease
45
virus infection
44
cervical cancer
44
mantle cell lymphoma
44
AIDS
43
ovarian cancer
42
synovial sarcoma
41
lymphoproliferative disorders
40
EMA
39
EBV infection
39
chronic myeloid leukemia
38
suicide
37
bladder cancer
36
Solitary fibrous tumor
36
epithelial ovarian cancer
35
autoimmune disease
35
endometrial cancer
35
primary tumor
33
neoplastic transformation
33
basal cell carcinoma
32
pancreatic cancer
32
minimal residual disease
32
lymphadenopathy
32
systemic lupus erythematosus
32
myeloid leukemia
31
glioblastoma
30
more...
Symptom
starvation
27
collapse
24
pain
17
splenomegaly
15
functional recovery
13
seizures
10
anesthesia
9
abdominal pain
8
headache
8
erythema
6
cough
5
hypothermia
5
weakness
5
fatigue
4
flank pain
4
hepatosplenomegaly
4
chest pain
4
cachexia
4
exhaustion
4
nausea
3
dyspnea
3
hyperoxia
3
acute stress
3
arthralgia
3
vomiting
3
back pain
3
shortness of breath
3
dry eye
3
ENT
2
fever of unknown origin
2
abdominal discomfort
2
myoclonus
2
thinning
2
abdominal fullness
2
skin damage
2
epigastric pain
2
stridor
2
hemoptysis
2
ataxia
2
autodigestion
2
hepatomegaly
2
diarrhea
2
neurological disability
2
Scratch
1
dysarthria
1
dysuria
1
pallor
1
masculinization
1
memory loss
1
pelvic pain
1
facial droop
1
tenesmus
1
heartburn
1
anosmia
1
cerebellar ataxia
1
cancer pain
1
flushing
1
Anoxia
1
tingling
1
polydipsia
1
leg edema
1
hemiplegia
1
precordial pain
1
respiratory distress
1
productive cough
1
myalgia
1
paresis
1
polyuria
1
hoarseness
1
chromosome marker
1
agitation
1
numbness
1
constipation
1
Neuropathic pain
1
menopausal symptoms
1
sore throat
1
tremor
1
Neurologic symptoms
1
blurred vision
1
disturbed balance
1
more...
Drug
IL-2
83
Dermatol
64
ROS
52
Paraffin
37
CSF
37
IFN-gamma
32
Taxol
23
ADR
23
Rituximab
22
MAP
22
Docetaxel
17
Adriamycin
16
Genasense
15
CED
14
Cardiovasc
14
vitamin E
13
Ginseng
10
CAM
10
G-CSF
10
ADM
10
BH4
10
Gel
10
Retinoic acid
9
ABC
9
p75
9
ascorbate
8
lysine
8
EE2
8
Taxotere
8
Arsenic trioxide
8
CPT-11
7
MDS
7
Monit
7
NADH
7
DNase I
6
CTX
6
Bortezomib
6
Indomethacin
6
Mutagen
5
TTC
5
Glutathione
5
Campath
5
Campath
5
PTH
5
Ethanol
5
Fludarabine
5
Heme
4
G418
4
AMC
4
ZnO
4
Zoledronic acid
4
Herceptin
4
DEX
4
MDM
4
VCR
4
Flavopiridol
4
Gefitinib
4
ICI
4
Growth hormone
4
Growth hormone
4
Etoposide
4
VCR
4
DHT
3
BLyS
3
Clopidogrel
3
DHT
3
Zoledronic acid
3
Rasagiline
3
Sorafenib
3
Angiotensin II
3
AraC
3
NBT
3
MRC
3
TAC
3
AZT
3
AZT
3
ALA
3
Vitamin K2
2
Trabectedin
2
uPA
2
more...
Enzyme
caspase-3
812
mitogen-activated protein kinase
197
ERK
175
caspase-9
169
CD10
160
superoxide dismutase
154
PARP
143
protein kinase
120
catalase
92
protein kinase C
87
caspase-8
77
caspase-1
70
reverse transcriptase
66
TdT
62
peroxidase
60
glutathione peroxidase
60
lactate dehydrogenase
56
cdc2
53
focal adhesion kinase
49
P-glycoprotein
46
topoisomerase
46
topoisomerase
40
luciferase
34
MEK
33
alanine aminotransferase
30
aspartate aminotransferase
29
glutathione S-transferase
29
cathepsin D
26
RNase
25
RNase
25
RNA polymerase
24
proteasome
23
phosphatidylinositol 3-kinase
22
prostate-specific antigen
22
alkaline phosphatase
22
transcriptase
21
caspase-7
21
calcineurin
21
caspase-2
20
caspase-7
19
caspase-2
17
endonuclease
17
AST
15
APC
14
granzyme B
14
ATPase
14
glyceraldehyde-3-phosphate dehydrogenase
14
transglutaminase
14
thymidylate synthase
14
NO synthase
13
beta-galactosidase
13
tyrosine hydroxylase
12
MDR
12
acetylcholinesterase
11
MAP
11
glutathione reductase
11
complex I
11
lysozyme
9
GSK
9
collagenase
9
thymidine phosphorylase
8
cathepsin B
8
AMP-activated protein kinase
8
CD13
8
phosphoinositide 3-kinase
8
MPP
8
phospholipase C
8
creatine kinase
8
DNA polymerase
7
chloramphenicol acetyltransferase
7
caspase-6
7
dihydrofolate reductase
7
thymidine kinase
7
trypsin
7
phosphodiesterase
7
NADPH oxidase
6
glyceraldehyde-3-phosphate dehydrogenase
6
urokinase-type plasminogen activator
6
renin
6
caspase-6
6
more...
Compound
DNA
1456
Dec
556
Clin
393
oxygen
342
MTT
236
dUTP
173
calcium
157
retinoic acid
113
TNF
108
glucose
105
MDA
89
nitric oxide
88
iodine
80
GSH
79
GSH
79
hydrogen
74
sodium
73
bromide
69
water
67
tyrosine
65
acetate
62
glutamate
55
cysteine
51
ATP
48
H2O2
45
serine
39
ethanol
36
cAMP
34
Asp
34
ADR
34
ADP-ribose
33
N-acetylcysteine
32
zinc
32
Adriamycin
27
nitrogen
27
MEK
27
boron
27
Neuronal
27
alanine
27
phosphate
26
ADP
25
TNM
25
acridine
24
VP-16
24
arginine
24
iron
23
AMP
22
Curcumin
22
Estrogen
22
DDP
22
formaldehyde
21
methionine
21
PMA
21
ADP
20
ADP
20
potassium
19
silver
19
Hoechst 33342
19
PMA
18
NH2
18
Estrogen
18
vitamin D
17
threonine
17
CAT
17
CAT
17
copper
17
CAT
17
PEG
16
creatinine
15
galactose
15
salt
15
Androgen
15
DMSO
15
Pac
15
Ara-C
14
selenium
14
sulfate
14
5-FU
13
leucine
13
nickel
13
more...