Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:A9QXG9 (bcl-2)
 7,497 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
bcl-2 7497
p53 1895
bax 1524
Bcl-2 1309
caspase-3 962
Sep 512
c-myc 454
Mol 397
Ki-67 382
lymphoid 332
Fas 332
proto-oncogene 300
p21 299
CD34 246
Bcl-X 234
cytochrome c 223
caspase-9 212
bcl-x 209
cytokine 198
proliferating cell nuclear antigen 189
Bax protein 175
cyclin D1 174
CD10 160
vimentin 159
CD20 144
survivin 142
PARP 130
anti-apoptotic protein 126
non-Hodgkin's lymphoma 125
MIB 124
superoxide dismutase 122
annexin V 119
tumor necrosis factor 119
erbB-2 115
estrogen receptor 114
p27 114
caspase-8 111
Bcl-6 111
nodal 110
TNF 108
CD95 103
IL-6 97
IgG3 97
CD99 96
TdT 96
ras 95
CD4 93
CD5 93
c-fos 92
cyclin D 88
mutant p53 87
cytokeratin 87
collagen 86
desmin 84
IL-2 83
APO-1 80
vascular endothelial growth factor 80
Fas ligand 78
IgH 78
thymus 76
GSH 76
catalase 75
CD8 73
epidermal growth factor receptor 70
membrane protein 67
cyclin 66
TNF-alpha 66
VEGF 65
c-kit 64
progesterone receptor 64
p38 63
p16 61
glutathione peroxidase 60
JNK 60
CD23 60
inhibitor of apoptosis 59
endoplasmic reticulum 59
poly(ADP-ribose) polymerase 58
p65 58
MAPK 58
fas 56
smooth muscle actin 56
cytochrome 55
PC-3 53
inducible nitric oxide synthase 53
interferon 52
ROS 52
ERK 52
PI3K 51
IL-4 51
lactate dehydrogenase 50
androgen receptor 49
ATP 48
CD30 48
CD56 47
SOD 47
survival factor 47
AKT 47
ERK1 46
cyclin E 46
STAT3 45
mTOR 45
all-trans 45
COX-2 45
insulin 45
P-glycoprotein 45
WAF1 44
neu 44
Mcl-1 43
AE1 42
Bak 42
E-cadherin 42
CD44 42
FasL 42
CD117 42
c-Jun 42
nerve growth factor 41
CLL 41
p63 41
CD45 41
EGFR 41
CD95L 40
heavy chain 40
CD31 40
S100 40
brain-derived neurotrophic factor 40
IL-10 40
CD40 39
EMA 39
CPP32 39
synaptophysin 39
mdm2 39
ICE 38
peroxidase 37
tyrosine kinase 37
IFN 37
IL-3 37
CD43 37
cyclin A 37
Polymerase 36
MMP-9 36
CHOP 36
BAX 35
HER2 35
LMP 35
cyclooxygenase-2 34
AP-1 34
Burkitt lymphoma 34
AE3 33
IFN-gamma 33
c-Myc 33
glial fibrillary acidic protein 33
pro-apoptotic protein 33
TCR 33
neuron-specific enolase 32
CD38 32
CIP1 32
interleukin-6 31
glycoprotein 31
CD68 31
more...
Disease
tumor 1702
cancer 1618
lymphoma 606
carcinoma 474
leukemia 344
breast cancer 330
follicular lymphoma 259
B-cell lymphoma 237
Hodgkin's disease 226
carcinogenesis 214
tumorigenesis 212
prostate cancer 187
Epstein 173
metastases 171
MCF 169
tumor growth 156
non-Hodgkin's lymphoma 146
ischemia 140
adenocarcinoma 135
B-cell lymphomas 132
chronic lymphocytic leukemia 124
squamous cell carcinoma 124
melanoma 120
lung cancer 114
acute myeloid leukemia 112
hepatocellular carcinoma 108
tumor progression 107
chronic lymphocytic leukemia 101
Leukemia 95
Burkitt's lymphoma 89
multiple myeloma 85
GSH 76
neuroblastoma 75
glioma 71
dysplasia 67
colorectal cancer 64
acute lymphoblastic leukemia 63
colon cancer 62
gastric cancer 62
non-small cell lung cancer 60
adenoma 59
cerebral ischemia 59
Alzheimer's disease 59
retinoblastoma 58
diabetes 58
HIV 58
stroke 56
mucosa-associated lymphoid tissue 54
acute promyelocytic leukemia 53
lung carcinoma 52
immunodeficiency 51
sarcoma 50
B-cell chronic lymphocytic leukemia 46
Parkinson's disease 45
aggressiveness 45
cervical cancer 44
virus infection 44
mantle cell lymphoma 44
AIDS 43
ovarian cancer 42
synovial sarcoma 41
lymphoproliferative disorders 40
EBV infection 39
EMA 39
chronic myeloid leukemia 38
suicide 37
bladder cancer 36
Solitary fibrous tumor 36
epithelial ovarian cancer 35
autoimmune disease 35
endometrial cancer 35
neoplastic transformation 33
primary tumor 33
minimal residual disease 32
pancreatic cancer 32
lymphadenopathy 32
systemic lupus erythematosus 32
basal cell carcinoma 32
myeloid leukemia 31
glioblastoma 30
myelodysplastic syndrome 29
osteosarcoma 28
pheochromocytoma 26
residual disease 25
atherosclerosis 25
CEM 25
T-cell lymphomas 25
WT1 24
heart failure 24
ductal carcinoma in situ 24
aggression 24
small cell lung cancer 24
NHL 24
rheumatoid arthritis 23
SCID 23
infectious diseases 22
hypertension 22
T-cell lymphoma 21
hemangiopericytoma 21
liver cancer 21
Kaposi's sarcoma 21
renal cell carcinoma 20
solid tumor 20
skin cancer 20
esophageal cancer 19
uterine cervix 19
Infection 18
herpes simplex 18
esophageal cancer 18
plaque 18
acute leukemia 17
hepatitis C 17
carcinoma in situ 17
FAS 17
small lymphocytic lymphoma 17
lymphocytosis 17
depression 16
Diffuse large B-cell lymphoma 16
endometrial adenocarcinoma 16
dementia 15
osteoarthritis 15
myocardial ischemia 15
Dukes 15
uterus 15
hematologic malignancies 15
meningioma 15
cirrhosis 15
ductal carcinoma 15
familial adenomatous polyposis 14
herpes 14
lymphoblastic leukemia 14
APC 14
chronic hepatitis 14
mesothelioma 14
multiple sclerosis 13
carcinoid 13
leukemogenesis 13
invasive cancer 13
thymoma 13
DDP 13
marginal zone lymphoma 13
hyperglycemia 13
oral cancer 13
myocardial infarction 13
metastatic melanoma 13
metastatic breast cancer 13
leiomyosarcoma 13
adult T-cell leukemia/lymphoma 13
PSA 12
cutaneous T-cell lymphoma 12
erythroleukemia 12
amyotrophic lateral sclerosis 12
epithelial tumor 12
renal disease 12
high-grade lymphomas 12
cytomegalovirus 12
mole 12
cardiomyopathy 11
brain tumor 11
laryngeal squamous cell carcinoma 11
more...
Symptom
starvation 27
collapse 24
pain 17
splenomegaly 15
functional recovery 13
seizures 10
anesthesia 9
abdominal pain 8
headache 8
erythema 6
cough 5
hypothermia 5
weakness 5
fatigue 4
flank pain 4
hepatosplenomegaly 4
chest pain 4
cachexia 4
exhaustion 4
nausea 3
dyspnea 3
hyperoxia 3
acute stress 3
arthralgia 3
vomiting 3
back pain 3
shortness of breath 3
dry eye 3
ENT 2
fever of unknown origin 2
abdominal discomfort 2
myoclonus 2
thinning 2
abdominal fullness 2
skin damage 2
epigastric pain 2
stridor 2
hemoptysis 2
ataxia 2
autodigestion 2
hepatomegaly 2
diarrhea 2
neurological disability 2
Scratch 1
dysarthria 1
dysuria 1
pallor 1
masculinization 1
memory loss 1
pelvic pain 1
facial droop 1
tenesmus 1
heartburn 1
anosmia 1
cerebellar ataxia 1
cancer pain 1
flushing 1
Anoxia 1
tingling 1
polydipsia 1
leg edema 1
hemiplegia 1
precordial pain 1
respiratory distress 1
productive cough 1
myalgia 1
paresis 1
polyuria 1
hoarseness 1
chromosome marker 1
agitation 1
numbness 1
constipation 1
Neuropathic pain 1
menopausal symptoms 1
sore throat 1
tremor 1
Neurologic symptoms 1
blurred vision 1
disturbed balance 1
bone pain 1
DNA marker 1
Drug
IL-2 83
Dermatol 64
ROS 52
Paraffin 37
CSF 37
IFN-gamma 32
ADR 23
Taxol 23
Rituximab 22
MAP 22
Docetaxel 17
Adriamycin 16
Genasense 15
CED 14
Cardiovasc 14
vitamin E 13
Gel 10
CAM 10
ADM 10
G-CSF 10
Ginseng 10
BH4 10
ABC 9
Retinoic acid 9
p75 9
EE2 8
Arsenic trioxide 8
lysine 8
ascorbate 8
Taxotere 8
NADH 7
CPT-11 7
MDS 7
Monit 7
DNase I 6
CTX 6
Indomethacin 6
Bortezomib 6
Fludarabine 5
PTH 5
Mutagen 5
Glutathione 5
Ethanol 5
Campath 5
TTC 5
Campath 5
ICI 4
Flavopiridol 4
Heme 4
Zoledronic acid 4
AMC 4
MDM 4
VCR 4
Etoposide 4
G418 4
ZnO 4
Herceptin 4
Growth hormone 4
Gefitinib 4
DEX 4
VCR 4
Growth hormone 4
DHT 3
Rasagiline 3
Sorafenib 3
BLyS 3
AraC 3
Zoledronic acid 3
Angiotensin II 3
MRC 3
Clopidogrel 3
AZT 3
TAC 3
AZT 3
ALA 3
DHT 3
NBT 3
PTC 2
CCL 2
Teniposide 2
Artesunate 2
Vitamin K2 2
-deoxyadenosine 2
Simvastatin 2
ARA-C 2
Nitric Oxide 2
Spectrum 2
Trabectedin 2
Asn 2
Troglitazone 2
Tibolone 2
Amifostine 2
CTX 2
CDX 2
Estrogens 2
lactose 2
KCL 2
Thyroglobulin 2
ZnCl2 2
Prozac 2
CTX 2
EPA 2
R1881 2
CDX 2
Lovastatin 2
ENT 2
Portal 2
TiO2 2
uPA 2
ZnCl2 2
PCB 1
Tacrolimus 1
Acyclovir 1
ddI 1
Donepezil 1
Xanthium 1
Compound 15 1
Sandostatin 1
Loxoribine 1
Lenalidomide 1
NOV 1
Casodex 1
Acacia 1
MTC 1
Tannic acid 1
Fructose 1
Dial 1
CaCl2 1
Parkin 1
Acemannan 1
Poloxamer 188 1
Swainsonine 1
Mesalazine 1
Glycyrrhiza 1
Retinoic Acid 1
Cellcept 1
Miltefosine 1
balanced salt solution 1
CaCl2 1
TRM 1
Dried yeast 1
Spectrum 1
Tao 1
ROC 1
Mycophenolic acid 1
Imiquimod 1
HCG 1
Silica 1
Finasteride 1
Meth 1
Phenytoin 1
Florfenicol 1
Tubocurarine 1
Myricetin 1
TAT 1
Aliskiren 1
ampicillin 1
Hoelen 1
Cellcept 1
Bexarotene 1
more...
Enzyme
caspase-3 812
mitogen-activated protein kinase 197
ERK 175
caspase-9 169
CD10 160
superoxide dismutase 154
PARP 143
protein kinase 120
catalase 92
protein kinase C 87
caspase-8 77
caspase-1 70
reverse transcriptase 66
TdT 62
glutathione peroxidase 60
peroxidase 60
lactate dehydrogenase 56
cdc2 53
focal adhesion kinase 49
P-glycoprotein 46
topoisomerase 46
topoisomerase 40
luciferase 34
MEK 33
alanine aminotransferase 30
aspartate aminotransferase 29
glutathione S-transferase 29
cathepsin D 26
RNase 25
RNase 25
RNA polymerase 24
proteasome 23
prostate-specific antigen 22
phosphatidylinositol 3-kinase 22
alkaline phosphatase 22
caspase-7 21
calcineurin 21
transcriptase 21
caspase-2 20
caspase-7 19
caspase-2 17
endonuclease 17
AST 15
glyceraldehyde-3-phosphate dehydrogenase 14
thymidylate synthase 14
transglutaminase 14
APC 14
ATPase 14
granzyme B 14
beta-galactosidase 13
NO synthase 13
tyrosine hydroxylase 12
MDR 12
complex I 11
MAP 11
acetylcholinesterase 11
glutathione reductase 11
lysozyme 9
GSK 9
collagenase 9
cathepsin B 8
phospholipase C 8
phosphoinositide 3-kinase 8
CD13 8
thymidine phosphorylase 8
MPP 8
AMP-activated protein kinase 8
creatine kinase 8
phosphodiesterase 7
DNA polymerase 7
chloramphenicol acetyltransferase 7
trypsin 7
caspase-6 7
thymidine kinase 7
dihydrofolate reductase 7
succinate dehydrogenase 6
glyceraldehyde-3-phosphate dehydrogenase 6
renin 6
AMPK 6
caspase-6 6
lipoxygenase 6
DNA methyltransferase 6
caspase-4 6
NADPH oxidase 6
glyceraldehyde-3-phosphate dehydrogenase 6
AMPK 6
DNase 6
DCF 6
NOS 6
ACS 6
glyceraldehyde-3-phosphate dehydrogenase 6
dihydropyrimidine dehydrogenase 6
urokinase-type plasminogen activator 6
NADPH oxidase 6
glyceraldehyde-3-phosphate dehydrogenase 6
dihydropyrimidine dehydrogenase 6
prostate-specific membrane antigen 5
tyrosinase 5
caspase-10 5
adenosine deaminase 5
ACE 5
IKK 5
ribonuclease 5
MEKK1 5
ribonuclease 5
NQO1 5
caspase-10 5
TSP-1 5
gamma-glutamyl transpeptidase 5
heme oxygenase 4
adenosine deaminase 4
ATP synthase 4
tissue plasminogen activator 4
aldehyde dehydrogenase 4
matrix metalloproteinase 2 4
carbonic anhydrase 4
ornithine decarboxylase 4
phospholipase A2 4
MMP 4
neutral sphingomyelinase 4
enolase 3
HSD 3
choline acetyltransferase 3
DNA ligase 3
DNA ligase 3
guanylate cyclase 3
aldehyde dehydrogenase 3
aldehyde dehydrogenase 3
BAL 3
RNase H 3
PKG 3
glutamine synthetase 3
thrombin 3
aldehyde dehydrogenase 3
MIP 3
aldehyde dehydrogenase 3
matrix metalloproteinase 9 3
TSA 3
12-lipoxygenase 3
cGMP phosphodiesterase 2
15-lipoxygenase 2
isocitrate dehydrogenase 2
isocitrate dehydrogenase 2
5alpha-reductase 2
HIV-1 protease 2
sphingosine kinase 2
5alpha-reductase 2
BMT 2
caspase-4 2
neuraminidase 2
ADP-ribosyltransferase 2
IMP dehydrogenase 2
UDP-glucuronosyltransferase 2
ADP-ribosyltransferase 2
myrosinase 2
chymase 2
indoleamine 2,3-dioxygenase 2
asparaginase 2
pyruvate kinase 2
CaMKII 2
more...
Compound
DNA 1456
Dec 556
Clin 393
oxygen 342
MTT 236
dUTP 173
calcium 157
retinoic acid 113
TNF 108
glucose 105
MDA 89
nitric oxide 88
iodine 80
GSH 79
GSH 79
hydrogen 74
sodium 73
bromide 69
water 67
tyrosine 65
acetate 62
glutamate 55
cysteine 51
ATP 48
H2O2 45
serine 39
ethanol 36
ADR 34
cAMP 34
Asp 34
ADP-ribose 33
N-acetylcysteine 32
zinc 32
MEK 27
Neuronal 27
Adriamycin 27
alanine 27
boron 27
nitrogen 27
phosphate 26
ADP 25
TNM 25
acridine 24
arginine 24
VP-16 24
iron 23
DDP 22
Estrogen 22
Curcumin 22
AMP 22
formaldehyde 21
methionine 21
PMA 21
ADP 20
ADP 20
potassium 19
Hoechst 33342 19
silver 19
Estrogen 18
NH2 18
PMA 18
threonine 17
CAT 17
CAT 17
CAT 17
vitamin D 17
copper 17
PEG 16
DMSO 15
creatinine 15
Pac 15
salt 15
galactose 15
Androgen 15
sulfate 14
Ara-C 14
selenium 14
Cereb 13
urea 13
5-FU 13
nickel 13
leucine 13
DBA 13
CAM 13
glutamine 13
Ara-C 13
UTP 12
THP 12
Docetaxel 12
anthracene 12
DCC 12
MAP 12
THP 12
MDR 12
Progesterone 11
Melatonin 11
pyrimidine 11
pyrimidine 11
FK506 10
butyric acid 10
BCR 10
PEG 10
cobalt 10
Cyt 10
Genistein 10
ethyl acetate 10
Paclitaxel 10
ASA 10
lysine 10
SCC 10
Estradiol 10
Glutamate 10
Valproic acid 9
diacetate 9
cadmium 9
Rapamycin 9
Cytochrome c 9
SDS 9
nicotinamide 9
PGE2 9
CO2 9
BCG 9
Insulin 9
ammonium 9
Dexamethasone 8
pyrrolidine 8
ATF 8
Phe 8
TPA 8
NAD 8
MPP 8
Histone 8
Gly 8
Neo 8
dATP 8
pyrrolidine 8
TPA 8
BCNU 8
MPP 8
Vimentin 8
Tanshinone 7
nitrate 7
butyric acid 7
pyrene 7
CPT-11 7
Tamoxifen 7
aldehyde 7
MIA 7
Staurosporine 7
Methamphetamine 7
methanol 7
Resveratrol 7
His 7
uridine 7
Sulforaphane 7
Staurosporine 7
acrylamide 7
Tamoxifen 7
ACNU 7
Retinal 7
more...