Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:A7KAX9 (grit)
1,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Enamel demineralization occurring adjacent to directly bonded orthodontic attachments is of great concern to orthodontists. The topical application of fluorides to enamel surfaces before acid etching and the bonding of the attachments is not recommended by many investigators. The objective of this study was to determine the enamel fluoride acquired from various topical fluoride agents and to determine the effect of the acquired fluoride on the tensile bond strength of an orthodontic bonding system. Fifty extracted maxillary central incisors were mounted in cups and the facial surfaces of the crowns were polished on 600-grit silicon carbide paper. Enamel microbiopsies were performed just off the midpoint of each tooth. Ten teeth served as controls and received no topical fluoride treatment, while a similar number were treated with either APF, SnF2, Duraphat, or Fluor Protector. The teeth were suspended in synthetic saliva 4 minutes after fluoride application. The topical fluoride agents were removed after 24 hours and the teeth were again suspended in synthetic saliva at 37 degrees C for 7 days. Enamel biopsies were again performed just off the midpoint of each tooth on the side not previously biopsied. The enamel surfaces were etched for 1 minute and the tensile bond strength of Concise orthodontic bonding system to the etched enamel surfaces was determined. The enamel surfaces acquired significantly different amounts of fluoride from the topical fluoride agents, but the bond strengths to these surfaces were not significantly different. The results of this in vitro study suggest that the application of topical fluoride agents to enamel surfaces 7 days before the bonding of orthodontic attachments will not have an adverse effect on bond strength.
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PMID:The effect of topical fluoride treatment on enamel fluoride uptake and the tensile bond strength of an orthodontic bonding resin. 315 23

The purpose of this study was to evaluate the effect of an APF gel treatment on the shear bond strength of a resin composite to enamel. A total of 45 noncarious human extracted permanent molars were used. A flat enamel surface was obtained with 600 grit silicon carbide paper and cleansed with a rubber cup and a water slurry of fine flour of pumice. The teeth were randomly distributed into three groups of 15 teeth each: Group 1: Etched for 30 sec with 37% orthophosphoric acid gel (control); Group 2: APF treatment (Topex gel--Sultan Dental Products, Englewood, NJ) for 1 min and then etched as in Group 1; Group 3: APF gel treatment for 4 min and then etched as in Group 1. After etching, rinsing, and drying, an unfilled resin (XR-Bond--Kerr Manufacturing Co., Romulus, MI) was applied thinly with a brush and cured for 20 sec. A nylon ring (internal diameter: 6.69 mm2) was placed over the area and filled with a light-cured composite resin (Herculite XR--Kerr Manufacturing Co., Romulus, MI). The teeth were thermocycled (x500), mounted in plastic cups and plaster, and sheared with a knife-edged blade in an Instron Testing Machine (Instron Engineering Corp., Canton, MA) running at a crosshead speed of 0.5 mm/min. The results in MPa were as follows: Group 1: 24.88 +/- 6.16; Group 2: 23.20 +/- 5.11; Group 3: 21.29 +/- 8.44. An ANOVA and Student-Newman-Keuls procedure revealed no statistically significant difference among the groups.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Shear bond strength of a resin composite to enamel treated with an APF gel. 824 3