Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:A7KAX9 (grit)
 1,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The purpose of this study was to characterize changes in the surface chemistry of dentin following various adhesive treatments. The coronal parts of sound freshly extracted third molars were cross-sectioned over the pulp chambers, each producing a pair of dentin samples which were polished to 600 grit and cleaned with 3% H2O2. The first sample of each pair was used as a control, while the second one was subjected to one of the following adhesive treatments: (a) Gluma Cleanser, (b) Tenure Conditioner, (c) Scotchprep, (d) Gluma Cleanser/Gluma Primer, (e) Tenure Conditioner/Tenure Solution A&B, or (f) Scotchprep/Scotchbond 2 Adhesive. The treated samples paired with their respective controls were studied by small-area ESCA spectroscopy. Three areas of 1.0 mm in diameter randomly chosen on each sample were analyzed by survey and C1s, O1s, N1s high-resolution spectra. The samples from groups d, e, and f were additionally subjected to argon-ion-depth profiling of the uppermost 2-nm layer at 0.5-nm intervals. According to the results, treatment modes a, b, and c caused the reduction of carbonates and increased the -NH/NH2 ratio. Treatments a and c increased the alcohol groups, while treatments b and c increased the carbonyl and ether groups. All these changes were in comparison to the reference dentin specimens. Dentin treatment with d, e, and f induced a complex in depth distribution of the C, N, O binding states. The energy shifts detected do not indicate primary bonding of the tested adhesives to the dental substrate.
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PMID:Surface reactions of adhesives on dentin. 208 97

Surface roughness is one of the most influential criteria affecting the durability and strength of the adhesive restorative materials to the dentine. This study was carried out to investigate the roughness of the dentine surface after some of the modalities proposed for its treatment prior to application of the DBA. Dentine surface roughness of the sixty teeth divided into 12 groups were tested where the dentine surfaces were denuded and were brought to a similar 600 grit surface roughness then different treatments were carried out using H2O2, CO2 gas laser at 30 and 48 J/cm2 energy densities, EDTA and polyacrylic acid treatments. The dentine surface roughness was determined using a profilometer and the results were digitized and plotted using an AUTO-CAD software and Rolland plotter to compare the effects of the different treatments on the dentine surface roughness of the tested samples. Results revealed that the laser treatment left smooth dentine surface and added further evidences to the simplicity and reliability of the conventional use of EDTA and the polyacrylic acid according to the type of adhesive to be used.
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PMID:Dentine roughness after different surface treatments. 829 36

Hydrogen peroxide solution can be very effective for cleaning grit filled wounds and grazes. Its use in Accident and Emergency (A&E) departments has gone out of vogue due to concerns about air emboli formation. This article discusses the truth behind these concerns and whether it is in fact safe to use hydrogen peroxide solution for wound cleaning in specific situations.
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PMID:Where have all the bubbles gone? An ode to Hydrogen peroxide, the champagne of all wound cleaners. 1263 24

Cell-titanium interactions are crucial to the clinical success of bone and dental implants. The physico-chemical characteristics of the substrates surface influence osteoblast proliferation, differentiation, and activity as well. The osteoblast behavior was analyzed on three different titanium surfaces: ground with an abrasive 600 grit SiC paper, blasted with alumina particles (65 microm diameter) and alumina blasted followed by a double chemical etch (4% HF+4% HF/8% H2O2). Scanning electron microscopy (SEM) and profilometry showed distinct microtopographies. Ground samples showed parallel-groove orientation. The Al2O3-blasted surface presented the roughest microtopography with aluminum-rich particles incrusted in the titanium surface. Osteoblasts cells from femora of Balb/c mice were seeded onto the substrates tested. Cell morphology and initial attachment were evaluated by SEM. Osteoblasts adhered to and spread on all samples tested. However, on rough surfaces, osteoblasts did not spread completely and acquired a polygonal morphology. Besides, the cell proliferation rate was diminished at the beginning of incubation on rough surfaces. Our results suggest a delay, rather than an impairment, in osteoblast viability and alkaline phosphatase activity when cells are cultured on rough surfaces, inducing a distinct osteoblast phenotype, rather than blocking its activity. At least in the culture conditions used in this work, alumina particles did not affect osteoblast behavior.
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PMID:Effect of three distinct treatments of titanium surface on osteoblast attachment, proliferation, and differentiation. 1630 73