Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:A7KAX9 (grit)
 1,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The purpose of this study was to assess the surface free energy of a series of composite resin restorative materials, utilizing the concept of critical surface tension (yc). Cylindrical samples of 20 mm diameter and 2 mm in thickness were prepared from 4 microfilled, 3 hybrid and 6 small particle composite resins. The critical surface tension was determined by contact angle measurements on 1000 grit ground surfaces. A Zisman series of homologous liquids was used (Water, Glycerol, Formamide, Thiodiglycol, Dilodormethane, I-Bromonapthalane). The recorded yc means were 30.000-42.600 dyn/cm for microfilled, 42.47-44.68 dyn/cm for hybrid and 42.19-49.20 dyn/cm for small particle composites. In all the cases the work of wetting was primary attributed to non polar and dispersion forces. The type and the concentration of the reinforcing fillers is the major factor influencing yc, especially in the presence of hydrophylic particles like Ba. Microfilled materials showed decreased wetting efficiency. Hydrophobic monomers do not provide any significant advantage on the wettability of polished composite surfaces.
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PMID:[Evaluation of the critical surface tension (gc) of composite resins]. 213 Mar 25

A study was conducted which examined the influence of electropolishing on the corrosion resistance of a cold rolled 316L stainless steel. Test specimens were surface prepared to a final mechanical finish of wetted 600 grit SiC paper, prior to electropolishing. An o-H3PO4/Glycerol/H2O electropolishing solution was employed for times of 15, 20, and 25 min. Control specimens were surface prepared only to the final mechanical finish. Anodic polarization tests were performed in a deaerated Ringer's solution (37 degrees C) which was acidified to pH 1, with HCl. The electropolished specimens demonstrated increased corrosion resistance, when compared to the control specimens. This was evidenced for the former by more anodic corrosion and breakdown potentials, and the absence of a dissolution peak which was observed for the control specimens at the initial polarization potentials. Surface hardness measurements indicated that this increase in corrosion resistance was produced, in part, by the removal of the cold worked surface layer produced by the mechanical finish. In terms of increasing corrosion resistance, no optimum electropolishing time was found within the 15-25 min treatment period.
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PMID:The influence of electropolishing on the corrosion resistance of 316L stainless steel. 734 65

We present a gentle mechanical method for the noninvasive transepidermal delivery of topically applied optical skin clearing agents. Optical skin clearing reduces light scattering in highly turbid skin with the aid of hyperosmotic chemicals such as glycerol, polyethylene glycol, and solutions of dextrose. Transepidermal delivery of such agents is believed to be most patient compliant and most likely to be used in a clinical environment. Optical skin clearing has the potential to expand the current limited use of laser light in medicine for diagnostic and therapeutic applications. Light scattering limits the penetration depth of collimated light into skin. In order to increase the diffusion of topically applied optical skin clearing agents into skin, we present a gentle mechanical delivery method involving glycerol and dextrose as optical skin clearing agents and fine 220-grit sandpaper to rub the clearing agent into the tissue. Gentle rubbing causes abrasion of the superficial skin layer including the stratum corneum, which otherwise prevents these optical skin clearing agents from freely diffusing into skin. Results indicate very fast optical skin clearing rates. In vivo hamster skin turned transparent within 2 min. The 1e light penetration depth increased by 36+/-3.75% for dextrose and 43+/-8.24% for glycerol. Optical skin clearing was reversed using phosphate buffered saline solution. Skin viability was observed 70 h post-treatment and showed scabbing and erythema on a few percent of the total optically cleared skin surface.
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PMID:Using sandpaper for noninvasive transepidermal optical skin clearing agent delivery. 1696 46

The aim of this study was to characterize the mechanical properties and drug elution features of silk protein-based electrodeposited dental implant coatings. Silk processing conditions were modified to obtain coatings with a range of mechanical properties on titanium studs. These coatings were assessed for adhesive strength and dissolution, with properties tuned using water vapor annealing or glycerol incorporation to modulate crystalline content. Coating reproducibility was demonstrated over a range of silk concentrations from 1% to 10%. Surface roughness of titanium substrates was altered using industry relevant acid etching and grit blasting, and the effect of surface topography on silk coating adhesion was assessed. Florescent compounds were incorporated into the silk coatings, which were modulated for crystalline content, to achieve four days of sustained release of the compounds. This silk electrogelation technique offers a safe and relatively simple approach to generate mechanically robust, biocompatible, and degradable implant coatings that can also be functionalized with bioactive compounds to modulate the local regenerative tissue environment.
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PMID:Electrodeposited silk coatings for bone implants. 2554 62