Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:A7KAX9 (grit)
 1,275 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The clinical performance of All Bond 2 and Bis-Fil M used with a total etch technique is being monitored in adult patients with erosion/abrasion lesions. 78 restorations were placed among 36 patients. After a prophylaxis, a short bevel was placed on the enamel margin. Using cotton roll isolation, both enamel and dentin were conditioned with 10% phosphoric acid for 20 seconds. Both tissues were moist at the time of primer application in which several applications of the latter resulted in a shiny surface upon gentle air drying. Bonding agent was added, brush thinned and polymerized for 20 seconds. The restoration was completed with the appropriate shade of composite placed in two increments and finished with fine grit diamonds and polishing paste. Evaluation criteria according to Ryge included retention, color match, visual and tactile margin integrity, secondary caries and postoperative sensitivity. A 1-year recall of 73 restorations showed 98.6% retention with 95.8% Alfa color match and stain-free margins. Tactile integrity was 83.1% Alfa. There was no secondary caries nor postoperative sensitivity. It was concluded that these preliminary findings offer cautious optimism for this system and the total etch procedure.
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PMID:Clinical evaluation of Class V restorations using a total etch technique: 1-year results. 780 11

A widely held belief among orthopedic surgeons is that there is no adhesion between polymethylmethacrylate bone cement and metal. However, a bond does form between the cement and the standard grit-blasted implant finish. Moreover, it has been shown that disruption of this bond or "debonding" of this interface is a major factor in the initiation of failure of some cemented total joint arthroplasties. It is the purpose of this study to determine the tensile pull-off strength of the bone cement-implant surface interface. A 1.27 cm (0.5 in) layer of Simplex-P bone cement was cured between two Co-Cr-Mo pins of 2.22 cm (0.875 in) diameter which had the standard implant finish on the surface that was interfaced with the cement. The specimens were tested in an MTS machine in stroke control with a cross head rate of 1 in per minute. The maximum load to failure was recorded. Bonding of the cement to the surface does occur. The tensile pull-off strength of the bone cement-implant surface interface is approximately 5 MPa. Other studies have shown that maintaining this bond between the stem and cement is important in maintaining the stability of cemented total joint arthroplasties.
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PMID:Tensile bonding strength of the cement-prosthesis interface. 819 Jun 80

The etched enamel-composite resin bond is the most reliable bond known to us. Moisture and dentin primers are the two most important variables that can interfere with this bond. This study investigated the effect of dentin primer on bond strengths of composite resin to moist and dry enamel. One hundred freshly extracted molar teeth were used for shear bond strength testing. The teeth were mounted in phenolic rings with an approximal enamel surface exposed. The exposed enamel surface on each tooth was flattened using 320- 400- and 600-grit silicon carbide papers and etched using 34-38% phosphoric acid gel. The teeth were then divided into 10 groups (n = 10). Four groups were assigned to each of the two dentin bonding systems, Scotchbond Multi-Purpose and OptiBond FL. Two groups were assigned to the single-bottle bonding agent (Single Bond). Each bonding system was tested on moist and dry enamel. OptiBond FL and Scotchbond MP were tested with and without the use of primer. All samples were thermocycled and tested in shear. Fracture analysis was performed using a binocular microscope. For scanning electron microscopy, approximal samples of enamel (1 mm thick) were flattened, etched, and bonded with and without primer on moist and dry enamel. A 1 mm-thick layer of Z100 was bonded to the specimens, which were then immersed in 10% HCl for 24 hours to dissolve the enamel. The specimens were viewed under a scanning electron microscope. Results indicated that the use of primer on dry enamel did not significantly affect (P > 0.05) shear bond strengths for the two bonding systems, Scotchbond MP (primed 24.10 +/- 4.83 MPa, unprimed 29.57 +/- 7.49 MPa) and OptiBond FL (primed 26.82 +/- 4.44, unprimed 25.66 +/- 2.95). However, the use of primer was found to be essential on moist enamel to obtain acceptable bond strengths with both Scotchbond MP (primed 25.61 +/- 10.29 MPa, unprimed 3.26 +/- 0.95 MPa) and OptiBond FL (primed 30.28 +/- 3.49 MPa, unprimed 8.37 +/- 3.31 MPa). Moisture on enamel did not significantly affect (P > 0.05) bond strengths for the single-bottle bonding agent, Single Bond (moist enamel 31.34 +/- 9.03 MPa, dry enamel 27.93 +/- 5.41 MPa). Fracture analysis revealed that most fractures were adhesive or mixed, with a greater percentage being cohesive for the groups with dry enamel or with primer on moist enamel. Scanning electron micrographs corroborated the shear bond strength data. The specimens without primer on moist enamel showed very poor penetration of adhesive and composite resin into the etched enamel microporosities.
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PMID:Effect of dentin primer on shear bond strength of composite resin to moist and dry enamel. 1120 91