Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1864663 (HCC)
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Human Gene/Protein
SEC13-like 1 isoform 13.4
RNA-binding motif protein 43 13.4
Chloride intracellular channel protein 2 13.4
LOC100129335 13.4
GLS2 protein 13.4
HCC 13.4
SCAN domain containing 3 13.4
LAMC1 protein 12.4
HCC5 12.4
HCCA2 12.4
FAM9C 12.4
RACGAP1P 11.8
HCCS1 11.8
HCDH 11.8
AFMID 11.8
Uridine-cytidine kinase 2 11.8
HCAP1 11.8
TDRD4 11.8
Hyccin 11.6
N-acetylneuraminic acid phosphate synthase 11.4
hepatocellular carcinoma suppressor 1 11.4
TRMT11 11.4
URG11 11.4
RFTN1 11.4
H2A.3 11.1
FAM126A 11.1
NUP37 11.1
diacylglycerol kinase kappa 11.1
ZC3H3 10.8
histone H2A.1 10.8
erasin 10.8
actin, alpha 2, smooth muscle, aorta 10.8
OATP5A1 10.6
SSR3 10.6
checkpoint with forkhead and ring finger domains 10.6
KM-HN-1 10.6
AZ3B 10.6
HCC2 10.4
nitric oxide synthase 2A 10.4
HINT2 10.4
C5orf30 10.4
NXF3 10.4
GP73 10.2
HCC3 10.2
IWS1 10.2
HIST1H2BJ 10.2
CTDSP2 10.2
CALML3 10.2
HIST2H2BE 10.2
SNCG protein 10.2
TMC4 10.2
SLC25A26 10.2
NLRP11 10.2
HTPAP 10.2
CMTM2 10.1
PJA1 10.1
Peptidyl-prolyl cis-trans isomerase 10.1
Staphylococcal nuclease domain-containing protein 1 10.1
INHBC 10.1
CMTM1 10.1
OXSR1 9.9
exportin 5 9.9
HNRNP 9.9
ORP8 9.9
TDRD5 9.8
ASC2 9.8
OATP6A1 9.8
PCDH20 9.7
UL16-binding protein 2 9.7
MAGE-4 protein 9.7
PFDN5 9.7
GATAD2A 9.7
protein kinase TTK 9.6
SYF2 9.6
OCT6 9.6
DLEU7 9.6
chloride intracellular channel 4 9.5
GEMIN4 9.5
hRad50 9.5
C-myc protein 9.5
more...
Disease
HCC 13.4
Hepatobiliary neoplasms 12.4
Metastasis to spleen 11.8
liver cancer 11.0
Fibrolamellar hepatocellular carcinoma 10.9
Other liver diseases 10.8
hepatocholangiocarcinoma 10.3
Chronic liver disease and cirrhosis 9.9
Radiation-induced liver disease 9.9
Primary liver cancer 9.7
MRX34 9.6
LEL 9.5
PCWH 9.4
Stenotrophomonas maltophilia infection 9.3
MILS 9.3
Hepatocarcinogenesis 9.2
pediatric liver cancer 9.0
CARASIL 8.9
hepatocellular carcinoma 8.8
biliary neoplasm 8.7
APUDoma 8.5
Demyelinating Polyneuropathy 8.3
Hepatic hemangioma 8.2
liver cancer 8.0
Acute viral hepatitis 7.7
GSD I 7.7
HFH 7.6
Cirrhosis 7.6
Hepatocellular carcinoma 7.5
Giant axonal neuropathy 7.5
Focal nodular hyperplasia 7.5
Chronic viral hepatitis 7.4
Oculodentodigital dysplasia 7.3
GSD 7.3
HCA 7.2
Aujeszky 7.2
hepatic adenoma 7.2
disorders of calcium metabolism 7.2
Klatskin 7.1
Hand-foot syndrome 7.1
cirrhosis 7.1
GSD 7.1
Pelizaeus-Merzbacher 7.1
hepatic neoplasm 7.0
Clonal evolution 6.9
Chronic hepatitis B 6.9
Chronic hepatitis C 6.7
chronic hepatitis 6.7
Recurrent tumor 6.7
lymphoepithelioma 6.7
Multiple tumors 6.7
Malignant disease 6.7
chronic liver disease 6.6
Chronic infection 6.4
Portal vein thrombosis 6.4
arterial embolization 6.4
DPD deficiency 6.4
Digestive Diseases 6.3
MODY3 6.3
DTD 6.3
EMT 6.1
hepatitis B 6.1
tyrosinemia 6.1
Alcoholic liver disease 6.1
viral hepatitis 6.1
chronic persistent hepatitis 6.1
liver disease 6.1
CMTX 6.1
Squamous Cell Carcinoma 6.1
MEST 6.1
GAN 6.0
LGM 6.0
tropical sprue 6.0
bile duct stenosis 6.0
FHL2 6.0
HS3 6.0
chronic active hepatitis 5.9
HCV coinfection 5.9
liver fibrosis 5.9
coproporphyria 5.9
more...
Symptom
left upper quadrant pain 6.3
No adverse effect 6.1
right upper quadrant pain 5.6
Tenderness 4.8
Spots 4.6
abdominal discomfort 4.2
hepatomegaly 4.0
leg edema 4.0
eds 3.3
hypoproteinemia 3.2
night sweats 3.2
exhaustion 2.5
acute abdominal pain 2.4
chronic cough 2.4
leg pain 2.4
tense 2.3
anorexia 2.2
abdominal pain 2.2
splenomegaly 2.1
HSA 1.8
hemoptysis 1.8
bone pain 1.8
nausea 1.7
epigastric pain 1.6
hemiplegia 1.4
chills 1.3
acute stress 1.2
fatigue 1.2
vomiting 1.0
Ill 0.9
paresis 0.9
back pain 0.8
starvation 0.8
spasticity 0.7
myalgia 0.7
arthralgia 0.6
diarrhea 0.4
chest pain 0.3
syncope 0.2
dyspnea 0.2
collapse 0.2
nausea and vomiting 0.2
discomfort -0.1
cough -0.2
discomfort -0.2
weakness -0.2
acidity -0.5
headache -0.8
respiratory distress -0.9
pain -0.9
angina -1.0
overweight -1.3
seizures -2.9
anesthesia -3.4
Drug
Livact 11.8
1,2,4-Triazole 9.1
Doxifluridine 9.1
Mangafodipir trisodium 8.8
Nexavar 8.7
Lipiodol 8.5
Nitisinone 8.4
Resovist 8.2
Sorafenib 8.1
Telbivudine 8.0
Levovist 7.7
Gd-BOPTA 7.6
Pirarubicin 6.9
Compound 16 6.7
Compound 18 6.6
Celebrex 6.4
Sonazoid 6.0
Tolvaptan 5.6
Entecavir 5.6
Entecavir 5.6
Pirfenidone 5.5
CTM 5.5
MTC 5.4
GEO 5.1
Vena 5.1
Vena 5.1
CTM 5.0
Everolimus 4.9
Optison 4.9
Erlotinib 4.8
AGG 4.8
Tenofovir 4.7
HCH 4.6
Liraglutide 4.6
BoNT/A 4.6
LCM 4.6
LCM 4.6
Hyaluronidase 4.6
Oxaliplatin 4.5
Portal 4.5
Hyaluronidase 4.4
Adriamycin 4.4
Imiquimod 4.3
CTC 4.3
ROC 4.3
Indocyanine green 4.3
BTC 4.2
Gefitinib 4.2
VCR 4.1
CTC 4.0
PDL 4.0
HCG 4.0
ADR 4.0
Albumin 4.0
Gelfoam 3.9
DMSA 3.8
Herceptin 3.8
BH4 3.8
PMPA 3.8
ADM 3.8
VCR 3.8
Irinotecan 3.7
PTC 3.6
SF6 3.6
Docetaxel 3.6
Cetuximab 3.5
ROS 3.5
NVP 3.4
Diphenhydramine 3.4
EPI 3.3
G418 3.3
Etoposide 3.2
Aloe 3.1
ABC 3.1
IL-1ra 3.0
Vitamin K 2.9
CTA 2.9
Glycyrrhiza 2.9
Prednisolone 2.8
balanced salt solution 2.8
more...
Enzyme
TACE 9.4
GSase 7.4
glycine N-methyltransferase 7.1
heparitinase I 7.0
EC 2.7.7.9 6.5
lipoate acetyltransferase 6.1
tetanus neurotoxin 5.7
PMT 5.7
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.7
HCS 5.7
glucose-6-phosphatase 5.6
inositol 3-kinase 5.5
AST 5.5
eEF2 kinase 5.5
O-GlcNAc transferase 5.4
AGT 5.4
dihydropyrimidine dehydrogenase 5.3
HPI 5.1
gamma-glutamyl transpeptidase 5.0
alanine aminotransferase 4.9
peptidylarginine deiminase 4.9
prostacyclin synthase 4.8
SST 4.8
dihydropyrimidine dehydrogenase 4.7
caspase-7 4.6
caspase-7 4.5
uroporphyrinogen decarboxylase 4.5
caspase-6 4.5
aspartate aminotransferase 4.5
caspase-6 4.4
asparagine synthetase 4.4
meprin 4.3
HK2 4.3
caspase-8 4.2
serine hydroxymethyltransferase 4.2
MTD 4.2
lysyl oxidase 4.1
15-hydroxyprostaglandin dehydrogenase 4.1
glutaminase 4.1
3-hydroxyacyl-CoA dehydrogenase 4.0
PDH 4.0
caspase-9 4.0
3-hydroxyacyl-CoA dehydrogenase 4.0
methionine adenosyltransferase 4.0
argininosuccinate synthetase 4.0
type III procollagen 3.9
alpha-L-fucosidase 3.9
arginase 3.8
CEP 3.8
microsomal epoxide hydrolase 3.7
caspase-3 3.7
BAT 3.7
GSK 3.7
TSP-1 3.6
luciferase 3.6
peroxiredoxin 3.6
phosphorylase kinase 3.6
ALDH 3.6
PARP 3.6
botulinum neurotoxin 3.5
cGMP phosphodiesterase 3.5
acyl-CoA oxidase 3.5
cytidine deaminase 3.4
ERK 3.4
cdc2 3.4
MMP 3.3
MDR 3.3
CEP 3.3
3-hydroxy-3-methylglutaryl-CoA reductase 3.3
CD13 3.2
TSA 3.1
lecithin:cholesterol acyltransferase 3.1
focal adhesion kinase 3.1
AMPK 3.1
glutamine synthetase 3.1
transketolase 3.0
MEK 2.9
glyceraldehyde-3-phosphate dehydrogenase 2.9
glyceraldehyde-3-phosphate dehydrogenase 2.9
glyceraldehyde-3-phosphate dehydrogenase 2.9
more...
Compound
1-dotriacontanol 12.4
3-Hydroxybiphenyl 11.8
1H-indole-2-carbohydrazide 11.1
3-chloro-1-butene 10.8
PHPS 10.2
Megestrol 10.2
2-(methylthio)ethanol 9.8
Ovatodiolide 9.5
5-hydroxyhexanoic acid 9.4
TACE 9.3
Eupafolin 9.1
Paraxanthine 9.1
aminomalonic acid 8.9
Clomazone 8.9
Ginkgolic acid 8.8
25-hydroxycholecalciferol 8.3
Sodium chlorate 8.1
NMOR 8.0
SHT 7.7
HCA 7.4
CPH 7.4
Cucurbitacin B 7.2
propiolic acid 7.1
C6H12 7.1
C6H12 7.0
hydrazinecarbothioamide 7.0
9,12-octadecadienoic acid 6.9
Vitexin 6.8
Epirubicin 6.7
CCC 6.7
CCC 6.7
D-erythrose 6.7
B 5 6.6
3-Deazaneplanocin 6.6
Aloe-emodin 6.6
NIX 6.6
DOD 6.6
Resazurin 6.5
Stigmasterol 6.5
Galangin 6.4
BOH 6.4
Oxymatrine 6.4
Esculetin 6.2
Bufalin 6.1
Xanthohumol 6.1
DEN 6.0
Isoliquiritigenin 6.0
CHM 6.0
FUDR 5.9
Thiotepa 5.9
N-Acetylglucosamine 5.8
Nelfinavir 5.8
Hesperetin 5.8
MUA 5.8
PMT 5.7
Aristolochic acid 5.7
Actinomycin 5.6
DFS 5.6
Relaxant 5.6
3TC 5.6
TIF 5.5
TNM 5.5
HEP 5.5
Matrine 5.5
Matrine 5.5
Matrine 5.5
Tetrandrine 5.4
Tetrandrine 5.4
Tetrandrine 5.4
HBC 5.4
Tetrandrine 5.4
Cyproheptadine 5.4
MTC 5.4
biphenylene 5.3
SSH 5.3
BSH 5.3
Diol 5.3
Lip 5.3
biphenylene 5.3
1H-1,2,4-triazole 5.2
more...