Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1864663 (
HCC
)
2,985
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HCC
2985
Sep
187
AFP
126
Mol
117
p53
115
alpha-fetoprotein
94
interferon
63
caspase-3
60
AKT
55
IFN
54
TACE
49
MRI
45
catenin
44
Bcl-2
43
PI3K
43
mTOR
40
albumin
38
MAPK
36
TNM
35
insulin
35
ERK
34
surface antigen
33
UTR
32
PLC
31
STAT3
31
vascular endothelial growth factor
29
VEGF
29
E-cadherin
29
cytokine
28
EGFR
28
AST
26
p21
26
TNF
25
IL-6
24
cyclin D1
24
proliferating cell nuclear antigen
23
prothrombin
22
p38
20
ROS
20
CD8
20
epidermal growth factor receptor
20
PD-L1
20
tyrosine kinase
20
aspartate aminotransferase
20
PEG
19
alkaline phosphatase
19
alanine aminotransferase
19
beta-catenin
19
EMT
19
cage
18
c-Myc
18
CD133
18
collagen
18
PTEN
18
MMP-9
17
NMR
17
caspase-8
17
Alpha-fetoprotein
16
histone
16
JNK
16
c-myc
16
cytochrome c
15
CD4
15
PD-1
15
hepatocyte growth factor
15
IL-10
15
CEA
15
endoplasmic reticulum
15
ERK1
15
serum albumin
14
caspase-9
14
glucose-6-phosphatase
14
TOF
14
proteasome
13
kit
13
p27
13
tumor necrosis factor
13
survivin
13
ATP
13
HGF
13
more...
Disease
hepatocellular carcinoma
2985
HCC
2985
liver cancer
2985
tumor
1069
cancer
896
cirrhosis
552
liver cancer
281
hepatitis B
252
chronic hepatitis
198
liver disease
195
hepatitis C
145
carcinoma
144
carcinogenesis
129
tumor growth
119
Hepatocellular carcinoma
109
hepatitis
108
metastases
105
tumorigenesis
94
breast cancer
90
chronic liver disease
83
tumor progression
80
virus infection
52
viral hepatitis
51
diabetes
48
liver fibrosis
46
adenoma
33
liver metastases
32
obesity
32
MCF
32
lung cancer
31
portal hypertension
27
acute hepatitis
27
fatty liver
26
adenocarcinoma
25
chronic active hepatitis
22
HIV
21
gastric cancer
20
Cirrhosis
20
colorectal cancer
19
EMT
19
colon cancer
19
arterial embolization
19
hemangioma
19
metabolic syndrome
19
alcoholic fatty liver
18
melanoma
16
Best
14
infectious diseases
13
HCA
13
non-small cell lung cancer
13
Nonalcoholic fatty liver
13
hepatoblastoma
13
HGF
13
dysplasia
12
lung metastases
12
tumor angiogenesis
12
hemochromatosis
12
primary tumor
12
pancreatic cancer
12
renal cell carcinoma
12
viremia
11
alcohol abuse
11
Primary liver cancer
11
anemia
11
aggressiveness
11
residual disease
11
esophageal varices
11
prostate cancer
10
ICC
10
hypertension
10
Chronic hepatitis B
10
ICC
10
Fibrolamellar hepatocellular carcinoma
10
leukemia
10
hepatic encephalopathy
9
GSD
9
neoplastic transformation
9
alcoholism
9
GSD
9
Chronic hepatitis C
9
more...
Symptom
abdominal pain
13
pain
13
fatigue
11
hepatomegaly
9
nausea
7
exhaustion
7
diarrhea
7
anorexia
6
vomiting
6
splenomegaly
4
starvation
4
abdominal discomfort
3
collapse
3
right upper quadrant pain
3
weakness
3
dyspnea
3
headache
3
No adverse effect
2
cough
2
hemoptysis
2
back pain
2
Ill
2
discomfort
2
discomfort
2
chest pain
2
Tenderness
1
myalgia
1
respiratory distress
1
arthralgia
1
angina
1
hypoproteinemia
1
epigastric pain
1
nausea and vomiting
1
anesthesia
1
night sweats
1
HSA
1
chronic cough
1
acute abdominal pain
1
eds
1
acute stress
1
acidity
1
bone pain
1
left upper quadrant pain
1
tense
1
leg pain
1
overweight
1
paresis
1
Spots
1
chills
1
seizures
1
spasticity
1
hemiplegia
1
syncope
1
leg edema
1
Drug
Sorafenib
40
Lipiodol
28
ROS
20
ROC
14
lysine
11
Portal
9
Adriamycin
9
HCH
8
Albumin
7
ABC
7
Levovist
5
IL-2
5
Ethanol
5
GEO
5
Biopolymers
4
Nexavar
4
ADM
4
ENT
4
IFN-gamma
4
HCG
4
Herceptin
3
Resovist
3
CTX
3
Gel
3
ADR
3
CTX
3
EE2
3
CTX
3
Cardiovasc
3
BoNT/A
2
Doxifluridine
2
MTC
2
VCR
2
CTC
2
Erlotinib
2
AGG
2
BH4
2
EPI
2
Docetaxel
2
MRC
2
Everolimus
2
Telbivudine
2
PTH
2
Retinoic acid
2
CTC
2
vitamin E
2
Oxaliplatin
2
PTC
2
Gd-BOPTA
2
Gefitinib
2
Monit
2
ascorbate
2
G418
2
Ginseng
1
Pirfenidone
1
niacin
1
BTC
1
Optison
1
G-CSF
1
Glutathione
1
Bayer
1
Compound 16
1
Entecavir
1
CTM
1
VCR
1
CTA
1
citric acid
1
Sonazoid
1
Vena
1
Indomethacin
1
Nephron
1
Spectrum
1
Asthma
1
CDP
1
Nitisinone
1
Vitamin K
1
Bifidobacterium
1
MAP
1
Tacrolimus
1
Nitric Oxide
1
more...
Enzyme
ERK
97
alanine aminotransferase
75
mitogen-activated protein kinase
63
TACE
49
aspartate aminotransferase
45
luciferase
44
caspase-3
43
focal adhesion kinase
36
gamma-glutamyl transpeptidase
27
AST
26
alkaline phosphatase
19
protein kinase
16
PARP
15
glucose-6-phosphatase
14
glutathione S-transferase
14
MEK
13
proteasome
13
ACS
12
caspase-8
12
caspase-9
11
superoxide dismutase
11
RNA polymerase
9
cdc2
8
GSK
8
AMP-activated protein kinase
7
AMPK
7
protein kinase C
7
reverse transcriptase
6
P-glycoprotein
5
arginase
5
ATPase
5
ACE
5
AMPK
5
glucose-6-phosphate dehydrogenase
4
urokinase-type plasminogen activator
4
lactate dehydrogenase
4
catalase
4
glyceraldehyde-3-phosphate dehydrogenase
4
DNA polymerase
4
phosphoinositide 3-kinase
4
MDR
4
glutamine synthetase
4
acetylcholinesterase
4
MMP
4
glyceraldehyde-3-phosphate dehydrogenase
4
NQO1
3
AGT
3
dihydropyrimidine dehydrogenase
3
peroxiredoxin
3
glutaminase
3
CD10
3
dihydropyrimidine dehydrogenase
3
endonuclease
3
glyceraldehyde-3-phosphate dehydrogenase
3
CD13
3
transcriptase
3
glyceraldehyde-3-phosphate dehydrogenase
3
glyceraldehyde-3-phosphate dehydrogenase
3
phosphorylase
3
DNA methyltransferase
3
pyruvate kinase
3
pyruvate dehydrogenase
2
RNase
2
adenylate cyclase
2
APC
2
plasmin
2
demethylase
2
caspase-7
2
caspase-7
2
ATP synthase
2
calcineurin
2
alcohol dehydrogenase
2
glycine N-methyltransferase
2
peroxidase
2
lysyl oxidase
2
pyruvate dehydrogenase
2
SST
2
adenosine deaminase
2
adenosine deaminase
2
PMT
2
more...
Compound
DNA
250
Dec
204
Clin
191
ethanol
65
MTT
53
oxygen
51
TACE
49
glucose
47
water
41
MDA
41
TNM
35
calcium
34
iron
27
TNF
25
phosphate
24
5-FU
23
25-hydroxycholecalciferol
23
methionine
23
PEG
21
PEG
20
sodium
19
CCC
18
CCC
18
tyrosine
18
vitamin D
16
alanine
16
Pac
15
Adriamycin
15
arginine
14
His
14
CO2
14
TOF
14
ATP
13
HCA
13
zinc
12
serine
12
copper
12
leucine
12
ASA
12
galactose
12
ACS
12
lysine
12
aflatoxin B1
12
ACS
12
iodine
11
MEK
11
GSH
10
GSH
10
acetate
10
PEI
10
DDP
10
PEI
10
threonine
10
glutamine
10
ADR
9
cysteine
9
hydrogen
9
Insulin
9
nitrogen
9
Phe
8
adenosylmethionine
8
retinoic acid
8
DEN
8
bromide
8
pyrimidine
7
phosphorus
7
ALP
7
pyrimidine
7
Ile
7
MMC
7
3TC
7
DTPA
6
nitric oxide
6
ammonia
6
Vimentin
6
acetic acid
6
CCl4
6
silver
6
sulfate
6
DFS
6
more...