Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1864663 (HCC)
 2,985 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HCC 2985
Sep 187
AFP 126
Mol 117
p53 115
alpha-fetoprotein 94
interferon 63
caspase-3 60
AKT 55
IFN 54
TACE 49
MRI 45
catenin 44
Bcl-2 43
PI3K 43
mTOR 40
albumin 38
MAPK 36
TNM 35
insulin 35
ERK 34
surface antigen 33
UTR 32
PLC 31
STAT3 31
E-cadherin 29
VEGF 29
vascular endothelial growth factor 29
cytokine 28
EGFR 28
AST 26
p21 26
TNF 25
IL-6 24
cyclin D1 24
proliferating cell nuclear antigen 23
prothrombin 22
p38 20
ROS 20
CD8 20
aspartate aminotransferase 20
PD-L1 20
tyrosine kinase 20
epidermal growth factor receptor 20
alkaline phosphatase 19
alanine aminotransferase 19
PEG 19
beta-catenin 19
EMT 19
cage 18
c-Myc 18
PTEN 18
collagen 18
CD133 18
MMP-9 17
NMR 17
caspase-8 17
c-myc 16
JNK 16
Alpha-fetoprotein 16
histone 16
cytochrome c 15
endoplasmic reticulum 15
CEA 15
CD4 15
IL-10 15
hepatocyte growth factor 15
PD-1 15
ERK1 15
caspase-9 14
serum albumin 14
TOF 14
glucose-6-phosphatase 14
matrix metalloproteinase 13
proteasome 13
HGF 13
ATP 13
p27 13
kit 13
tumor necrosis factor 13
survivin 13
She 12
histone deacetylase 12
hemochromatosis 12
ACS 12
interleukin-6 12
MMP-2 12
PARP 12
CCK 12
p65 12
HER2 12
ras 11
MEK 11
annexin V 11
N-cadherin 11
MMP2 11
EGF 11
Ki-67 11
LC3 11
polypeptide 11
CD31 11
c-Met 10
HLF 10
cytokeratin 19 10
HNE 10
BRCA1 10
HLA 10
Fas 10
gut 10
glypican 10
estrogen receptor 10
H2AX 10
SMA 10
ECM 10
p62 10
CD90 10
MET 9
epidermal growth factor 9
FDG 9
carcinoembryonic antigen 9
superoxide dismutase 9
TRAIL 9
IL-17 9
Cyclin D1 9
GSH 9
CD34 9
fibronectin 9
Pol 9
MMP9 9
cytokeratin 9
vimentin 9
CD44 9
tumour suppressor 9
GSD 9
MYC 8
CTNNB1 8
ubiquitin 8
Cytokine 8
interacting protein 8
lymphoid 8
parathyroid hormone 8
HSP70 8
A-I 8
scratch 8
CO2 8
Mcl-1 8
cyclin 8
GGT 8
colon carcinoma 7
MDR1 7
Bid 7
TGF-beta 7
glutathione S-transferase 7
CCA 7
G6Pase 7
lectin 7
GST 7
ALP 7
IL-8 7
osteopontin 7
more...
Disease
hepatocellular carcinoma 2985
liver cancer 2985
HCC 2985
tumor 1069
cancer 896
cirrhosis 552
liver cancer 281
hepatitis B 252
chronic hepatitis 198
liver disease 195
hepatitis C 145
carcinoma 144
carcinogenesis 129
tumor growth 119
Hepatocellular carcinoma 109
hepatitis 108
metastases 105
tumorigenesis 94
breast cancer 90
chronic liver disease 83
tumor progression 80
virus infection 52
viral hepatitis 51
diabetes 48
liver fibrosis 46
adenoma 33
obesity 32
liver metastases 32
MCF 32
lung cancer 31
portal hypertension 27
acute hepatitis 27
fatty liver 26
adenocarcinoma 25
chronic active hepatitis 22
HIV 21
Cirrhosis 20
gastric cancer 20
arterial embolization 19
colon cancer 19
colorectal cancer 19
metabolic syndrome 19
hemangioma 19
EMT 19
alcoholic fatty liver 18
melanoma 16
Best 14
HCA 13
Nonalcoholic fatty liver 13
infectious diseases 13
HGF 13
non-small cell lung cancer 13
hepatoblastoma 13
lung metastases 12
pancreatic cancer 12
primary tumor 12
renal cell carcinoma 12
tumor angiogenesis 12
hemochromatosis 12
dysplasia 12
viremia 11
esophageal varices 11
aggressiveness 11
Primary liver cancer 11
anemia 11
residual disease 11
alcohol abuse 11
ICC 10
leukemia 10
Chronic hepatitis B 10
Fibrolamellar hepatocellular carcinoma 10
prostate cancer 10
hypertension 10
ICC 10
neoplastic transformation 9
GSD 9
renal failure 9
Chronic hepatitis C 9
alcoholism 9
GSD 9
hepatic encephalopathy 9
GSH 9
Fanconi 8
SCID 8
ovarian cancer 8
type 2 diabetes 8
DDP 8
alcoholic cirrhosis 8
aggression 7
chronic persistent hepatitis 7
Epstein 7
schistosomiasis 7
tumor initiation 7
Hepatocarcinogenesis 7
primary biliary cirrhosis 7
osteomalacia 6
renal cancer 6
lymphoepithelioma 6
lung carcinoma 6
glycogen storage disease 6
HCG 6
cardiovascular disease 6
Chronic infection 6
lymphoma 6
EIA 6
MRT 6
LEL 6
solid tumor 6
iron overload 6
West 6
ischemia 6
Blocking 6
cholestasis 6
stroke 5
sarcoma 5
retinoblastoma 5
metabolic disorder 5
MTS 5
NOD 5
bone metastases 5
GSD I 5
mimicry 5
hypoglycemia 5
squamous cell carcinoma 5
depression 5
Budd-Chiari syndrome 5
encephalopathy 5
carcinoid 5
Still 5
chronic disease 5
SDS 5
tuberous sclerosis 5
gastrointestinal cancer 5
hyperlipidemia 5
hypercalcemia 5
hepatocholangiocarcinoma 4
Infection 4
renal disease 4
Lip 4
cervical cancer 4
cold 4
dyslipidemia 4
sepsis 4
Cholangiocarcinoma 4
familial adenomatous polyposis 4
Portal vein thrombosis 4
porphyria cutanea tarda 4
tetanus 4
varices 4
NAME 4
thrombocytopenia 4
myocardial infarction 4
NS3 4
non-Hodgkin's lymphoma 4
Cholangiocarcinoma 4
AS1 4
cholangitis 4
fibrosarcoma 4
FAS 4
sepsis 4
more...
Symptom
abdominal pain 13
pain 13
fatigue 11
hepatomegaly 9
nausea 7
exhaustion 7
diarrhea 7
anorexia 6
vomiting 6
splenomegaly 4
starvation 4
abdominal discomfort 3
collapse 3
right upper quadrant pain 3
weakness 3
dyspnea 3
headache 3
No adverse effect 2
cough 2
hemoptysis 2
back pain 2
Ill 2
discomfort 2
discomfort 2
chest pain 2
Tenderness 1
myalgia 1
respiratory distress 1
arthralgia 1
angina 1
hypoproteinemia 1
epigastric pain 1
nausea and vomiting 1
anesthesia 1
night sweats 1
HSA 1
chronic cough 1
acute abdominal pain 1
eds 1
acute stress 1
acidity 1
bone pain 1
left upper quadrant pain 1
tense 1
leg pain 1
overweight 1
paresis 1
Spots 1
chills 1
seizures 1
spasticity 1
hemiplegia 1
syncope 1
leg edema 1
Drug
Sorafenib 40
Lipiodol 28
ROS 20
ROC 14
lysine 11
Portal 9
Adriamycin 9
HCH 8
Albumin 7
ABC 7
IL-2 5
Levovist 5
Ethanol 5
GEO 5
Nexavar 4
ENT 4
ADM 4
IFN-gamma 4
Biopolymers 4
HCG 4
Herceptin 3
CTX 3
Gel 3
Resovist 3
Cardiovasc 3
CTX 3
EE2 3
ADR 3
CTX 3
Retinoic acid 2
Telbivudine 2
Gd-BOPTA 2
VCR 2
Erlotinib 2
BH4 2
Doxifluridine 2
Docetaxel 2
CTC 2
EPI 2
Monit 2
Everolimus 2
Gefitinib 2
PTC 2
AGG 2
CTC 2
Oxaliplatin 2
MTC 2
ascorbate 2
vitamin E 2
BoNT/A 2
MRC 2
G418 2
PTH 2
Cetuximab 1
niacin 1
TiO2 1
BTC 1
Celebrex 1
Optison 1
Nephron 1
Compound 16 1
Entecavir 1
G-CSF 1
Glutathione 1
Bayer 1
CTM 1
citric acid 1
VCR 1
CTA 1
Sonazoid 1
Vena 1
Indomethacin 1
Nephron 1
Spectrum 1
CDP 1
LCM 1
balanced salt solution 1
Asthma 1
Nitisinone 1
DNase I 1
Dermatol 1
Vitamin K 1
Bifidobacterium 1
SF6 1
Vena 1
MAP 1
Nitric Oxide 1
DMSA 1
Rituximab 1
Tacrolimus 1
Liraglutide 1
FAD 1
Mangafodipir trisodium 1
Ouabain 1
Hyaluronidase 1
uPA 1
CTM 1
Kenyan 1
Pirarubicin 1
Gelfoam 1
Indocyanine green 1
PDL 1
Tenofovir 1
PMPA 1
ALA 1
PCB 1
Vitamin E 1
CAM 1
Etoposide 1
Prednisolone 1
LCM 1
Imiquimod 1
Mutagen 1
Tolvaptan 1
ICI 1
Livact 1
1,2,4-Triazole 1
Irinotecan 1
Hyaluronidase 1
caffeine 1
THF 1
Angiotensin II 1
Diphenhydramine 1
Ginseng 1
Pirfenidone 1
Asn 1
Entecavir 1
Fragment 1
IL-1ra 1
Aloe 1
Compound 18 1
Glycyrrhiza 1
TAT 1
NVP 1
Enzyme
ERK 97
alanine aminotransferase 75
mitogen-activated protein kinase 63
TACE 49
aspartate aminotransferase 45
luciferase 44
caspase-3 43
focal adhesion kinase 36
gamma-glutamyl transpeptidase 27
AST 26
alkaline phosphatase 19
protein kinase 16
PARP 15
glutathione S-transferase 14
glucose-6-phosphatase 14
proteasome 13
MEK 13
ACS 12
caspase-8 12
superoxide dismutase 11
caspase-9 11
RNA polymerase 9
GSK 8
cdc2 8
protein kinase C 7
AMPK 7
AMP-activated protein kinase 7
reverse transcriptase 6
ACE 5
AMPK 5
arginase 5
ATPase 5
P-glycoprotein 5
glutamine synthetase 4
glucose-6-phosphate dehydrogenase 4
acetylcholinesterase 4
glyceraldehyde-3-phosphate dehydrogenase 4
urokinase-type plasminogen activator 4
glyceraldehyde-3-phosphate dehydrogenase 4
phosphoinositide 3-kinase 4
lactate dehydrogenase 4
catalase 4
MMP 4
DNA polymerase 4
MDR 4
CD13 3
endonuclease 3
glyceraldehyde-3-phosphate dehydrogenase 3
dihydropyrimidine dehydrogenase 3
CD10 3
glutaminase 3
phosphorylase 3
peroxiredoxin 3
NQO1 3
dihydropyrimidine dehydrogenase 3
glyceraldehyde-3-phosphate dehydrogenase 3
glyceraldehyde-3-phosphate dehydrogenase 3
transcriptase 3
DNA methyltransferase 3
AGT 3
pyruvate kinase 3
calcineurin 2
RNase 2
nitrogenase 2
caspase-7 2
demethylase 2
HCS 2
pyruvate dehydrogenase 2
adenylate cyclase 2
alcohol dehydrogenase 2
adenosine deaminase 2
plasmin 2
glycine N-methyltransferase 2
O-GlcNAc transferase 2
SST 2
peroxidase 2
phosphatidylinositol 3-kinase 2
pyruvate dehydrogenase 2
adenosine deaminase 2
APC 2
MIP 2
hexokinase 2
lysyl oxidase 2
botulinum neurotoxin 2
aldehyde dehydrogenase 2
PMT 2
collagenase 2
glutathione reductase 2
thrombin 2
caspase-7 2
pyruvate dehydrogenase 2
cholinesterase 2
RNase 2
ATP synthase 2
caspase-6 1
subtilisin 1
CYP3A4 1
MAT 1
tissue plasminogen activator 1
lysozyme 1
lecithin:cholesterol acyltransferase 1
thymidylate synthase 1
methionine adenosyltransferase 1
tyrosine hydroxylase 1
guanylate cyclase 1
HK2 1
GSase 1
PAM 1
choline acetyltransferase 1
NADPH oxidase 1
HSD 1
15-hydroxyprostaglandin dehydrogenase 1
BAT 1
TOR 1
granzyme B 1
NADPH oxidase 1
alpha-L-fucosidase 1
phosphatidylinositol-4,5-bisphosphate 3-kinase 1
aldolase 1
topoisomerase 1
isocitrate dehydrogenase 1
isocitrate dehydrogenase 1
chaperonin 1
transketolase 1
inositol 3-kinase 1
serine hydroxymethyltransferase 1
peptidylarginine deiminase 1
TSA 1
acid phosphatase 1
SPC 1
neuraminidase 1
enolase 1
phosphodiesterase 1
PDH 1
thymidine kinase 1
acyl-CoA oxidase 1
PAH 1
hyaluronidase 1
histidine kinase 1
CEP 1
cGMP phosphodiesterase 1
CEP 1
ALDH 1
topoisomerase 1
argininosuccinate synthetase 1
HPI 1
TAT 1
asparagine synthetase 1
3-hydroxy-3-methylglutaryl-CoA reductase 1
TSP-1 1
3-hydroxyacyl-CoA dehydrogenase 1
carbonic anhydrase 1
IKK 1
sulfatase 1
lipoate acetyltransferase 1
chondroitinase 1
chondroitinase 1
trypsin 1
cytidine deaminase 1
heparitinase I 1
more...
Compound
DNA 250
Dec 204
Clin 191
ethanol 65
MTT 53
oxygen 51
TACE 49
glucose 47
MDA 41
water 41
TNM 35
calcium 34
iron 27
TNF 25
phosphate 24
methionine 23
5-FU 23
25-hydroxycholecalciferol 23
PEG 21
PEG 20
sodium 19
CCC 18
CCC 18
tyrosine 18
alanine 16
vitamin D 16
Pac 15
Adriamycin 15
arginine 14
CO2 14
His 14
TOF 14
HCA 13
ATP 13
galactose 12
zinc 12
aflatoxin B1 12
copper 12
ASA 12
leucine 12
ACS 12
serine 12
lysine 12
ACS 12
MEK 11
iodine 11
GSH 10
GSH 10
acetate 10
threonine 10
PEI 10
glutamine 10
PEI 10
DDP 10
nitrogen 9
hydrogen 9
Insulin 9
ADR 9
cysteine 9
bromide 8
DEN 8
adenosylmethionine 8
retinoic acid 8
Phe 8
pyrimidine 7
Ile 7
3TC 7
phosphorus 7
MMC 7
ALP 7
pyrimidine 7
25-dihydroxycholecalciferol 6
DFS 6
Vimentin 6
silver 6
nitric oxide 6
ammonia 6
CCl4 6
sulfate 6
Paclitaxel 6
proline 6
DTPA 6
acetic acid 6
diacetate 5
NAD 5
GlcNAc 5
MDR 5
SDS 5
urea 5
Hoechst 33342 5
Lip 5
valine 5
chlorine 5
DMSO 5
MTS 5
hyaluronic acid 5
carbonate 5
THP 4
ADP-ribose 4
TEM 4
cadmium 4
Diazepam 4
GPT 4
Bilirubin 4
cAMP 4
CPH 4
palmitic acid 4
fluorine 4
THP 4
NAD 4
glycerol 4
Collagen 4
butyric acid 4
benzene 4
N-acetylcysteine 4
Epirubicin 4
glutamate 4
prostaglandin E1 3
FAP 3
vinyl 3
FAP 3
chalcone 3
ethyl acetate 3
PAR 3
palmitic acid 3
PPI 3
acridine 3
isoleucine 3
nickel 3
DCP 3
HCl 3
creatinine 3
isoleucine 3
DSM 3
manganese 3
PMA 3
selenium 3
cGMP 3
CTX 3
FK506 3
methanol 3
Cortisol 3
dUTP 3
DCP 3
HEP 3
Metformin 2
hexose 2
glucose-6-phosphate 2
quinazoline 2
HCO 2
Cytochrome c 2
Resveratrol 2
CTP 2
AAF 2
ADP 2
NADPH 2
tryptophan 2
8-OHdG 2
Bismuth 2
Cardiol 2
more...