Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1862200 (
RHE
)
1,093
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Thaliblastine exhibits dose dependent cytotoxic effect on HL-60, HL-60/DOX,
RHE
and HD-MY-2 leukemia cells. Additionally, typical for apoptosis oligonucleosomal DNA fragmentation could be detected in leukemia cells treated with thaliblastine. Moreover, an
MDR
-phenotype reversing effect of thaliblastine was also identified.
...
PMID:Effects of the plant alkaloid thaliblastine on non-cross-resistant and sensitive human leukemia cells in relation with reversal of acquired anthracycline resistance. 1556 48
