Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1832526 (
PCC
)
5,967
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Transfer RNAs (tRNA) are important molecules that involved in protein translation machinery and acts as a bridge between the ribosome and codon of the mRNA. The study of tRNA is evolving considerably in the fields of bacteria, plants, and animals. However, detailed genomic study of the cyanobacterial tRNA is lacking. Therefore, we conducted a study of cyanobacterial tRNA from 61 species. Analysis revealed that; cyanobacteria contain thirty-six to seventy-eight tRNA gens per genome that encodes for 20 tRNA isotypes. The number of iso-acceptors (anti-codons) ranged from thirty-two to forty-three per genome. tRNA
Ile
with anti-codon AAU, GAU, and UAU was reported to be absent from the genome of
Gleocapsa
PCC
73,106 and
Xenococcus
sp.
PCC
7305. Instead, they were contained anti-codon CAU that is common to tRNA
Met
and tRNA
Ile
as well. The iso-acceptors ACA (tRNA
Cys
), ACC (tRNA
Gly
), AGA, ACU (tRNA
Ser
), AAA (tRNA
Phe
), AGG (tRNA
Pro
), AAC (tRNA
Val
),
GCG
(tRNA
Arg
), AUG (tRNA
His
), and AUC (tRNA
Asp
) were absent from the genome of cyanobacterial lineages studied so far. A few of the cyanobacterial species encode suppressor tRNAs, whereas none of the species were found to encode a selenocysteine iso-acceptor. Cyanobacterial species encode a few putative novel tRNAs whose functions are yet to be elucidated.
...
PMID:Analysis of genomic tRNA revealed presence of novel genomic features in cyanobacterial tRNA. 3188 26
