Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1522102 (Melanoma)
 7,698 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
PCDHB11 12.0
ATP-binding cassette, sub-family B (MDR/TAP), member 5 12.0
TRAF3IP3 protein 12.0
ZNF781 12.0
FBRSL1 11.0
phospholipase A2, group VI 11.0
CTL-recognized antigen on melanoma 11.0
SPANX-C 11.0
SPANX-B 11.0
MAGEA12 10.7
HPS6 10.6
RQCD1 10.4
ZNF484 10.4
RBMXL1 10.4
vacuolar protein sorting 33A 10.4
MAGEA2 protein 10.4
NLRP1 protein 10.4
BLOC1S3 10.2
HPS5 10.1
MAGEC3 10.0
P2RY10 10.0
Peripheral myelin protein 2 10.0
ATP6V0B 10.0
MAGEA9 10.0
SPRR2F 10.0
SSXT 10.0
ATP-binding cassette subfamily B member 5 10.0
C10orf90 10.0
PLCXD1 10.0
MAGEA10 10.0
MAGE-B1 9.8
MAGEA2 9.7
translocon-associated protein delta 9.7
human homolog of mouse double minute 2 9.7
apolipoprotein L6 9.7
OS-9 protein 9.7
EYA1 protein 9.7
C10orf11 9.7
DTWD1 9.7
BRN2 9.6
TYRP1 protein 9.6
HPS3 9.5
DAPL1 9.4
MITF-C 9.4
ATP-binding cassette sub-family B member 5 9.4
TRAF3-interacting protein 3 9.4
RFPL1 9.4
RNA-binding motif protein 47 9.4
MBD3L2 9.4
BIVM 9.4
ZNF22 9.4
H2AFJ 9.4
melanoma inhibitory activity 9.3
ADP-ribosyltransferase 3 9.2
MAGEB4 9.2
TSPAN10 9.2
CT25 9.2
SLAMF9 9.2
MIA protein 9.2
ABCB5 9.2
MDA-9 9.1
GPR160 9.0
ABCB8 9.0
THOC2 9.0
SASS6 9.0
MAGE-F1 9.0
FAM129B 9.0
Melanoma-associated antigen 9.0
HPS4 9.0
FAM150A 9.0
CLDN11 9.0
PREX2 9.0
IL-24 8.9
PPP1R3C 8.8
neuregulin 4 8.8
Interleukin-24 8.8
C10orf99 8.8
T-box 2 8.8
mRNA-decapping enzyme 8.8
MYADM 8.7
more...
Disease
stage IIB melanoma 12.0
Melanoma 12.0
Meningeal melanomatosis 11.0
Blue vision 11.0
Familial Melanoma 10.4
Haemorrhagic pericarditis 10.0
melanoma stage 10.0
stage III melanoma 9.8
stage IV melanoma 9.7
stage II melanoma 9.5
Spinal meningioma 9.4
stage I melanoma 9.4
recurrent melanoma 9.4
Acral lentiginous melanoma 9.3
nodular malignant melanoma 9.2
metastatic melanoma 9.2
OCA4 9.2
cutaneous melanoma 9.2
benign nevi 9.1
melanoma in situ 9.1
Pigmented basal cell carcinoma 9.0
pigmented skin lesion 8.9
OCA1B 8.8
cancer associated retinopathy 8.8
melanoma 8.8
uveal melanoma 8.8
Melanocytoma 8.8
Melanocytoma 8.8
Chronic inflammatory disease 8.7
Mammary adenocarcinoma 8.7
ocular melanoma 8.6
Surgical menopause 8.6
Conjunctival melanoma 8.3
lentigo 8.3
skin cancer 8.2
dysplastic nevi 8.1
iris melanoma 8.1
multiple nevi 8.1
Melanoacanthoma 8.1
superficial spreading malignant melanoma 8.0
Congenital melanocytic nevus 7.9
Segmental vitiligo 7.9
Singleton-Merten syndrome 7.8
Sentinel node 7.8
Melanotic schwannoma 7.7
nerve sheath neoplasm 7.6
amelanotic melanoma 7.6
OCA3 7.6
OCM 7.5
Speckled lentiginous nevus 7.5
Xeroderma 7.5
Generalized vitiligo 7.3
Spitz nevus 7.3
Lentigo maligna 7.2
freckles 7.2
compound nevus 7.2
brain metastases 7.1
halo nevus 7.0
leukoderma 6.9
HPS2 6.9
cancer regression 6.9
vitiligo 6.8
blue nevus 6.8
Desmoplastic 6.8
Griscelli syndrome 6.8
allergic urticaria 6.7
VAIN 6.7
canities 6.7
Metastatic malignant melanoma 6.6
skin metastases 6.6
EBSS 6.5
CNS cancer 6.5
preneoplastic state 6.4
melanosis 6.3
Koebner 6.3
Breast metastases 6.3
cancer remission 6.3
Squamous Cell Carcinoma 6.3
Epidermal nevus syndrome 6.3
junctional nevus 6.3
more...
Symptom
Skin depigmentation 10.0
penile lesion 5.8
rectal pain 4.4
right lower quadrant pain 3.8
Scratch 3.4
Halo 3.2
pleuritic chest pain 2.8
skin damage 2.4
dysuria 2.3
clubbing 2.2
erythema 2.1
otalgia 2.0
dry skin 2.0
acute abdomen 2.0
nausea and vomiting 2.0
productive cough 1.9
decreased appetite 1.8
nausea 1.8
paresthesia 1.7
asthenia 1.6
nasal discharge 1.6
arthralgia 1.5
fatigue 1.4
photophobia 1.4
menopausal symptoms 1.3
myalgia 1.3
vomiting 1.2
cachexia 1.1
dysarthria 1.1
anorexia 1.1
acute abdominal pain 1.1
constipation 1.0
chills 1.0
skin irritation 0.9
vertigo 0.8
lethargy 0.5
diarrhea 0.5
hemoptysis 0.4
cancer pain 0.4
bone pain 0.4
abdominal pain 0.4
starvation 0.4
tinnitus 0.3
ataxia 0.1
dyspnea 0.0
sleepiness -0.0
myoclonus -0.0
headache -0.2
dizziness -0.2
ENT -0.4
weakness -0.4
paresis -0.5
hypotonia -0.5
flushing -0.6
exhaustion -0.7
discomfort -0.9
acidity -0.9
pain -0.9
discomfort -1.0
anesthesia -1.0
chest pain -1.1
overweight -1.1
syncope -1.2
distraction -1.2
respiratory distress -1.2
splenomegaly -1.3
seizures -1.3
Ill -1.4
thinning -1.4
cough -1.5
agitation -1.5
back pain -1.6
collapse -1.8
tremor -2.2
analgesia -2.8
Drug
Ecromeximab 12.0
Fotemustine 9.5
Ipilimumab 8.3
Roferon A 7.6
Proleukin 6.9
Cilengitide 6.8
Interferon alfa-2a 6.6
Intron A 6.6
Leukine 6.6
Intron A 6.5
Temodal 6.5
Sodium ascorbate 6.3
Intron A 6.2
Sesamol 6.2
Ciglitazone 5.7
Cangrelor 5.7
Lepirudin 5.6
Thymopentin 5.6
Tirapazamine 5.6
Flavopiridol 5.3
NOV 5.3
Ethyol 5.2
Cinnarizine 5.2
Vindesine 5.2
Vindesine 5.1
Axitinib 5.0
KAN 4.9
ID2 4.9
ROX 4.8
Aprepitant 4.7
NLF 4.7
Lead acetate 4.7
SNL 4.5
Retinoic Acid 4.4
Optison 4.4
Mitomycin-C 4.3
Tarceva 4.3
PDL 4.2
Isotretinoin 4.2
Magnevist 4.1
RAL 4.0
CDX 4.0
Photofrin II 4.0
Imiquimod 4.0
L-tyrosine 4.0
Paraffin 3.9
Retinoic acid 3.9
Nimesulide 3.8
NVP 3.7
DEL 3.6
CDX 3.6
Gelatin 3.6
Optison 3.6
Gleevec 3.5
Amifostine 3.5
Erlotinib 3.5
Sorafenib 3.5
GEO 3.4
Gefitinib 3.4
Pemetrexed 3.4
Bosentan 3.3
Bosentan 3.3
p75 3.3
Trifluoperazine 3.2
BLM 3.2
Photofrin 3.2
ISP 3.1
PFT 3.1
IFN-beta 3.0
Zoledronic acid 3.0
AIC 3.0
Denosumab 2.9
Clofibrate 2.9
Infliximab 2.9
Infliximab 2.9
Budesonide 2.7
Cremophor EL 2.7
VCR 2.7
R1881 2.7
CCL 2.7
more...
Enzyme
type III restriction enzyme 9.6
MGAT 7.3
GMP reductase 7.2
fucokinase 6.7
methioninase 6.7
tyrosinase 6.6
PGE2 isomerase 6.3
chondroitinase B 6.1
DCF 6.1
GD3 synthase 6.1
MHCK 5.9
EC 4.4.1.5 5.8
protein L-isoaspartyl methyltransferase 5.7
N-acetylglucosaminyltransferase V 5.7
MEK 5.7
matrix metalloproteinase 14 5.6
nicotinamide N-methyltransferase 5.5
RGP 5.2
PNL 5.2
methylthioadenosine phosphorylase 5.2
catechol oxidase 4.9
N-acetylgalactosaminidase 4.9
glycine N-methyltransferase 4.7
phenol oxidase 4.6
argininosuccinate synthetase 4.6
caspase-4 4.5
TSR 4.5
nicotinamide phosphoribosyltransferase 4.5
histamine N-methyltransferase 4.5
kynurenine 3-monooxygenase 4.4
NQO2 4.4
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.4
caspase-4 4.3
lysophospholipase D 4.2
phosphatidylethanolamine N-methyltransferase 4.2
ADE2 4.2
inositol 3-kinase 4.2
STK11 4.2
eEF2 kinase 4.1
3-mercaptopyruvate sulfurtransferase 4.1
proline oxidase 3.9
ALDH 3.8
chondroitinase AC 3.7
porphobilinogen deaminase 3.7
phosphoglycerate dehydrogenase 3.7
mitogen-activated protein kinase 3.6
ERK 3.5
SST 3.4
mannosidase II 3.4
peptidyl-prolyl cis-trans isomerase 3.4
DNA ligase 3.4
DNA ligase 3.4
caspase-9 3.4
HCS 3.3
PARP 3.3
lactate dehydrogenase 3.3
PAT 3.3
DNase II 3.3
Protein 2 3.3
caspase-7 3.2
caspase-7 3.2
matrix metalloproteinase 2 3.2
MMP 3.1
caspase-6 3.1
caspase-3 3.1
caspase-6 3.0
ribonucleotide reductase 3.0
dihydroorotate dehydrogenase 3.0
dihydroorotate dehydrogenase 3.0
thymidine phosphorylase 3.0
ADPase 2.9
matrix metalloproteinase 9 2.9
ribonucleotide reductase 2.9
urokinase-type plasminogen activator 2.8
MTD 2.8
arginase 2.7
DNA methyltransferase 2.7
cysteine synthase 2.7
factor C 2.7
phosphoinositide 3-kinase 2.7
more...
Compound
8-hydroxy-1,3,6-naphthalenetrisulfonic acid 12.0
2-benzyl-1H-benzo[de]isoquinoline-1,3(2H)-dione 12.0
3-hydroxyphenylalanine 9.8
3-hydroxyphenylalanine 9.8
3-hydroxyphenylalanine 9.8
3-hydroxyphenylalanine 9.8
methyl dihydrogen phosphate 9.2
Petasin 8.7
2-iodobenzamide 8.7
4-ethoxyphenol 8.6
2,4,6-octatrienoic acid 8.4
1-bromoheptane 8.3
Pectolinarigenin 8.3
Visnagin 8.3
PGF2beta 8.3
Biflorin 8.2
Apogossypol 8.2
Digitoxigenin 8.1
DHICA 8.1
2-Thiouracil 7.9
DIBA 7.6
2-Aminofluorene 7.6
L-dopachrome 7.6
3-hydroxyphenylethylamine 7.6
Ciprofloxacin hydrochloride 7.5
4-iodobenzamide 7.2
Ciprofloxacin hydrochloride 7.1
2-amino-1-butanol 7.1
2-amino-1-propanol 7.1
Fangchinoline 7.0
4-methoxybenzamide 7.0
Wedelolactone 7.0
Abietic acid 6.8
DIC 6.7
Dibenzoylmethane 6.6
Mezerein 6.5
Thiouracil 6.4
Melanin 6.2
Sesamol 6.2
GD3 6.2
Hinokitiol 6.1
PH2 6.1
isopropyl palmitate 6.1
Eriodictyol 6.1
MEK 6.0
N6-Methyladenosine 6.0
Sepiapterin 6.0
Tangeretin 5.8
Temozolomide 5.8
NOXA 5.8
BIF 5.7
Pinocembrin 5.7
FK520 5.7
Deoxyguanosine 5.6
KTS 5.6
MNT 5.5
2-butanol 5.5
Betulinic acid 5.4
SHB 5.4
IAN 5.3
DMDS 5.3
L-PAM 5.2
Deoxycytidine 5.2
L-PAM 5.2
DAHP 5.2
Plumbagin 5.2
p-Coumaric acid 5.2
DBI 5.1
GM2 5.1
Kojic acid 5.1
Toremifene 5.1
Galangin 5.0
Amonafide 5.0
Farnesyl diphosphate 5.0
DBI 5.0
SAN 4.9
Evodiamine 4.9
DDM 4.9
Evodiamine 4.8
Hypericin 4.8
more...