Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C1522102 (Melanoma)
7,698 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein BRAF 600 Sep 346 Mol 231 tyrosinase 223 MEK 203 interferon 161 cytokine 156 p53 150 NRAS 144 MAPK 120 nodal 117 ERK 105 IFN 104 AKT 103 interleukin-2 98 CDKN2A 96 caspase-3 94 CD8 93 PI3K 90 PD-1 88 KIT 85 MITF 83 Bcl-2 79 MEL 76 F10 76 collagen 73 HLA 68 MART-1 67 lactate dehydrogenase 65 microphthalmia-associated transcription factor 65 vascular endothelial growth factor 65 CDK4 64 p16 62 E-cadherin 61 CD4 60 CTLA-4 56 gp100 56 p21 54 RAF 54 PTEN 51 mTOR 50 interferon-alpha 47 S100 47 MAGE 47 endoplasmic reticulum 46 IL-8 44 IL-6 43 fibronectin 43 mda-7 43 ERK1 42 IL-24 42 IL-2 42 Melan-A 41 matrix metalloproteinase 39 PD1 39 tyrosine kinase 39 receptor tyrosine kinase 38 PD-L1 37 IL-10 37 glycoprotein 37 TNF 37 p38 37 STAT3 36 MSH 36 catenin 35 extracellular signal-regulated kinase 35 MC1R 35 vimentin 34 tumour suppressor 34 c-kit 34 tumor necrosis factor 34 HLA class I 34 interferon-gamma 33 HLA-A2 33 N-cadherin 33 CD44 33 chemokine 33 Tyrosinase 33 MMP-2 31 cyclin D1 31 more...

Disease Melanoma 7698 melanoma 7697 cancer 2370 tumor 2074 metastases 1122 metastatic melanoma 912 skin cancer 865 cutaneous melanoma 514 mole 381 tumor growth 274 tumor progression 177 uveal melanoma 168 mole 164 tumorigenesis 154 brain metastases 147 primary tumor 120 vitiligo 97 carcinoma 86 breast cancer 82 stage IV melanoma 79 squamous cell carcinoma 74 benign nevi 63 aggressiveness 63 lentigo 61 carcinogenesis 57 basal cell carcinoma 56 dysplastic nevi 55 leukemia 50 melanoma in situ 46 sarcoma 46 lung cancer 41 ocular melanoma 37 stage III melanoma 36 lung metastases 34 prostate cancer 31 liver metastases 31 lymphoma 30 skin tumor 28 adenocarcinoma 28 thrombocytopenia 26 amelanotic melanoma 26 mimicry 26 colitis 25 neuroblastoma 25 renal cell carcinoma 24 solid tumor 23 neutropenia 23 recurrent melanoma 22 ovarian cancer 22 tumor angiogenesis 22 SCID 20 colon cancer 20 GSH 20 skin disease 20 colorectal cancer 19 melanosis 19 glioma 19 bone metastases 19 retinoblastoma 18 Hodgkin's disease 18 influenza 18 rash 17 pancreatic cancer 17 hepatocellular carcinoma 17 Sentinel node 16 rare disease 16 glioblastoma 16 anemia 16 non-small cell lung cancer 15 keratosis 15 aggression 15 stage I melanoma 15 Hermansky-Pudlak syndrome 15 renal cancer 14 autoimmune disease 14 pneumonia 14 diabetes 14 virus infection 14 lung carcinoma 13 Adhesion 13 more...

Symptom fatigue 34 pain 33 nausea 20 diarrhea 20 vomiting 18 erythema 14 anesthesia 13 headache 12 abdominal pain 10 nausea and vomiting 9 seizures 8 starvation 8 dyspnea 7 weakness 7 anorexia 7 constipation 5 arthralgia 5 paresthesia 4 ataxia 4 myalgia 4 sleepiness 3 discomfort 3 overweight 3 acute abdomen 3 cachexia 3 discomfort 3 vertigo 3 dysuria 3 asthenia 2 tinnitus 2 acidity 2 chills 2 chest pain 2 respiratory distress 2 cough 2 hemoptysis 2 exhaustion 2 dizziness 2 collapse 2 lethargy 2 dysarthria 2 skin damage 2 paresis 1 Skin depigmentation 1 Ill 1 cancer pain 1 skin irritation 1 nasal discharge 1 rectal pain 1 flushing 1 decreased appetite 1 hypotonia 1 distraction 1 myoclonus 1 tremor 1 pleuritic chest pain 1 right lower quadrant pain 1 thinning 1 productive cough 1 back pain 1 agitation 1 analgesia 1 bone pain 1 photophobia 1 Halo 1 menopausal symptoms 1 Scratch 1 acute abdominal pain 1 syncope 1 clubbing 1 ENT 1 penile lesion 1 splenomegaly 1 dry skin 1 otalgia 1

Drug Dermatol 325 IL-2 44 Ipilimumab 31 IFN-gamma 26 ROS 24 CSF 22 lysine 17 Retinoic acid 12 Fotemustine 11 L-tyrosine 9 p75 9 MAP 8 Paraffin 8 ROC 8 ascorbate 7 IFN-beta 6 NADH 6 CAM 5 Monit 5 Leaf 5 Gelatin 5 Taxol 4 Sorafenib 4 Gleevec 4 Adriamycin 4 GEO 4 vitamin E 3 Alliance 3 Intron A 3 Isotretinoin 3 Mutagen 3 Imatinib 3 G418 3 PDL 3 uPA 3 CTX 3 Glutathione 3 Gefitinib 3 Cardiovasc 3 Intron A 3 NVP 3 BLM 3 CCL 2 Sesamol 2 NOV 2 caffeine 2 Flavopiridol 2 CPT-11 2 Imiquimod 2 Gel 2 Histamine 2 ABC 2 CTX 2 Spectrum 2 CTX 2 Intron A 2 Infliximab 2 Theophylline 2 Cilengitide 2 Photofrin 2 Retinoic Acid 2 Erlotinib 2 ETS 2 Ethanol 2 BH4 2 niacin 2 PCP 2 Infliximab 2 ID2 2 Estrogens 2 FAD 1 Ofloxacin 1 KAN 1 Cangrelor 1 Sodium ascorbate 1 Ouabain 1 Vitamin B 1 ADR 1 Interferon alfa-2a 1 Cinnarizine 1 more...

Enzyme mitogen-activated protein kinase 281 ERK 265 MEK 224 tyrosinase 212 caspase-3 74 lactate dehydrogenase 69 protein kinase 63 focal adhesion kinase 53 reverse transcriptase 47 luciferase 45 protein kinase C 42 PARP 33 DCF 32 caspase-9 19 urokinase-type plasminogen activator 18 catalase 17 proteasome 15 superoxide dismutase 14 glutathione S-transferase 13 AMP-activated protein kinase 13 collagenase 12 cdc2 11 thrombin 10 calcineurin 10 RNA polymerase 10 AMPK 10 phosphoinositide 3-kinase 9 MMP 9 caspase-8 9 AMPK 8 DNA methyltransferase 8 beta-galactosidase 8 phosphatidylinositol 3-kinase 8 MAP 8 P-glycoprotein 8 transcriptase 7 DNA ligase 7 DNA ligase 7 alkaline phosphatase 7 peroxidase 7 caspase-1 7 aldehyde dehydrogenase 7 trypsin 7 aldehyde dehydrogenase 6 aldehyde dehydrogenase 6 ACS 6 ribonucleotide reductase 6 aldehyde dehydrogenase 6 arginase 6 tissue plasminogen activator 6 aldehyde dehydrogenase 6 glutathione reductase 6 ATPase 6 hyaluronidase 5 ribonucleotide reductase 5 thromboplastin 5 phenol oxidase 5 topoisomerase 5 matrix metalloproteinase 2 5 topoisomerase 5 CD10 5 MDR 5 glyceraldehyde-3-phosphate dehydrogenase 5 plasmin 5 APC 5 thymidine kinase 5 adenylate cyclase 4 neuraminidase 4 NO synthase 4 RNase 4 cathepsin B 4 protein phosphatase 2A 4 RNase 4 gamma-glutamyl transpeptidase 4 thymidylate synthase 4 methioninase 4 dihydrofolate reductase 4 matrix metalloproteinase 9 4 argininosuccinate synthetase 4 enolase 4 more...

Compound Dec 651 DNA 440 Clin 225 MEK 203 oxygen 151 tyrosine 98 DIC 67 MTT 55 cysteine 43 calcium 41 retinoic acid 39 sodium 37 methionine 37 cAMP 37 TNF 37 glucose 31 arginine 30 serine 30 vitamin D 27 water 26 GD3 26 hydrogen 24 boron 24 lysine 24 TNM 23 GSH 22 GSH 22 acetate 21 ATP 21 iodine 20 bromide 20 sulfate 20 Melanin 19 nitric oxide 19 leucine 19 His 18 iron 18 AMP 17 zinc 17 threonine 16 phosphate 16 BCNU 15 Asp 15 MDA 15 GM3 14 tryptophan 14 galactose 14 fluorine 14 alanine 14 nitrogen 14 GM2 14 Curcumin 13 urea 13 Gly 13 PEG 12 GTP 12 DDP 12 glutamate 12 proline 11 Temozolomide 11 Optimal 11 copper 11 ADP 11 tryptophan 10 ADP 10 pyrimidine 10 selenium 10 ADP 10 pyrimidine 10 Phe 9 tryptophan 9 Melatonin 9 nicotinamide 9 acridine 9 L-DOPA 9 MIA 9 PEG 9 phenol 9 tryptophan 9 Vimentin 8 more...

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