Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C1522102 (Melanoma)
7,698 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein BRAF 600 Sep 346 Mol 231 tyrosinase 223 MEK 203 interferon 161 cytokine 156 p53 150 NRAS 144 MAPK 120 nodal 117 ERK 105 IFN 104 AKT 103 interleukin-2 98 CDKN2A 96 caspase-3 94 CD8 93 PI3K 90 PD-1 88 KIT 85 MITF 83 Bcl-2 79 F10 76 MEL 76 collagen 73 HLA 68 MART-1 67 microphthalmia-associated transcription factor 65 lactate dehydrogenase 65 vascular endothelial growth factor 65 CDK4 64 p16 62 E-cadherin 61 CD4 60 CTLA-4 56 gp100 56 p21 54 RAF 54 PTEN 51 more...

Disease Melanoma 7698 melanoma 7697 cancer 2370 tumor 2074 metastases 1122 metastatic melanoma 912 skin cancer 865 cutaneous melanoma 514 mole 381 tumor growth 274 tumor progression 177 uveal melanoma 168 mole 164 tumorigenesis 154 brain metastases 147 primary tumor 120 vitiligo 97 carcinoma 86 breast cancer 82 stage IV melanoma 79 squamous cell carcinoma 74 aggressiveness 63 benign nevi 63 lentigo 61 carcinogenesis 57 basal cell carcinoma 56 dysplastic nevi 55 leukemia 50 melanoma in situ 46 sarcoma 46 lung cancer 41 ocular melanoma 37 stage III melanoma 36 lung metastases 34 prostate cancer 31 liver metastases 31 lymphoma 30 skin tumor 28 adenocarcinoma 28 thrombocytopenia 26 more...

Symptom fatigue 34 pain 33 diarrhea 20 nausea 20 vomiting 18 erythema 14 anesthesia 13 headache 12 abdominal pain 10 nausea and vomiting 9 starvation 8 seizures 8 dyspnea 7 anorexia 7 weakness 7 arthralgia 5 constipation 5 ataxia 4 paresthesia 4 myalgia 4 cachexia 3 dysuria 3 overweight 3 discomfort 3 acute abdomen 3 discomfort 3 sleepiness 3 vertigo 3 asthenia 2 exhaustion 2 hemoptysis 2 collapse 2 tinnitus 2 acidity 2 chills 2 dizziness 2 dysarthria 2 cough 2 respiratory distress 2 chest pain 2 more...

Drug Dermatol 325 IL-2 44 Ipilimumab 31 IFN-gamma 26 ROS 24 CSF 22 lysine 17 Retinoic acid 12 Fotemustine 11 p75 9 L-tyrosine 9 ROC 8 Paraffin 8 MAP 8 ascorbate 7 IFN-beta 6 NADH 6 Gelatin 5 Monit 5 CAM 5 Leaf 5 Gleevec 4 Taxol 4 Sorafenib 4 Adriamycin 4 GEO 4 Imatinib 3 PDL 3 BLM 3 vitamin E 3 uPA 3 NVP 3 G418 3 Mutagen 3 Alliance 3 CTX 3 Isotretinoin 3 Gefitinib 3 Cardiovasc 3 Intron A 3 more...

Enzyme mitogen-activated protein kinase 281 ERK 265 MEK 224 tyrosinase 212 caspase-3 74 lactate dehydrogenase 69 protein kinase 63 focal adhesion kinase 53 reverse transcriptase 47 luciferase 45 protein kinase C 42 PARP 33 DCF 32 caspase-9 19 urokinase-type plasminogen activator 18 catalase 17 proteasome 15 superoxide dismutase 14 AMP-activated protein kinase 13 glutathione S-transferase 13 collagenase 12 cdc2 11 thrombin 10 AMPK 10 RNA polymerase 10 calcineurin 10 MMP 9 phosphoinositide 3-kinase 9 caspase-8 9 DNA methyltransferase 8 MAP 8 beta-galactosidase 8 AMPK 8 phosphatidylinositol 3-kinase 8 P-glycoprotein 8 caspase-1 7 trypsin 7 transcriptase 7 DNA ligase 7 peroxidase 7 more...

Compound Dec 651 DNA 440 Clin 225 MEK 203 oxygen 151 tyrosine 98 DIC 67 MTT 55 cysteine 43 calcium 41 retinoic acid 39 sodium 37 TNF 37 cAMP 37 methionine 37 glucose 31 serine 30 arginine 30 vitamin D 27 GD3 26 water 26 hydrogen 24 boron 24 lysine 24 TNM 23 GSH 22 GSH 22 ATP 21 acetate 21 bromide 20 sulfate 20 iodine 20 nitric oxide 19 Melanin 19 leucine 19 iron 18 His 18 AMP 17 zinc 17 threonine 16 more...

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