Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1522102 (Melanoma)
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Human Gene/Protein
ATP-binding cassette, sub-family B (MDR/TAP), member 5 12.0
ZNF781 12.0
TRAF3IP3 protein 12.0
PCDHB11 12.0
phospholipase A2, group VI 11.0
SPANX-C 11.0
CTL-recognized antigen on melanoma 11.0
FBRSL1 11.0
SPANX-B 11.0
MAGEA12 10.7
HPS6 10.6
ZNF484 10.4
RBMXL1 10.4
MAGEA2 protein 10.4
RQCD1 10.4
NLRP1 protein 10.4
vacuolar protein sorting 33A 10.4
BLOC1S3 10.2
HPS5 10.1
MAGEC3 10.0
more...
Disease
Melanoma 12.0
stage IIB melanoma 12.0
Meningeal melanomatosis 11.0
Blue vision 11.0
Familial Melanoma 10.4
Haemorrhagic pericarditis 10.0
melanoma stage 10.0
stage III melanoma 9.8
stage IV melanoma 9.7
stage II melanoma 9.5
Spinal meningioma 9.4
stage I melanoma 9.4
recurrent melanoma 9.4
Acral lentiginous melanoma 9.3
nodular malignant melanoma 9.2
metastatic melanoma 9.2
OCA4 9.2
cutaneous melanoma 9.2
benign nevi 9.1
melanoma in situ 9.1
more...
Symptom
Skin depigmentation 10.0
penile lesion 5.8
rectal pain 4.4
right lower quadrant pain 3.8
Scratch 3.4
Halo 3.2
pleuritic chest pain 2.8
skin damage 2.4
dysuria 2.3
clubbing 2.2
erythema 2.1
otalgia 2.0
dry skin 2.0
acute abdomen 2.0
nausea and vomiting 2.0
productive cough 1.9
decreased appetite 1.8
nausea 1.8
paresthesia 1.7
asthenia 1.6
more...
Drug
Ecromeximab 12.0
Fotemustine 9.5
Ipilimumab 8.3
Roferon A 7.6
Proleukin 6.9
Cilengitide 6.8
Interferon alfa-2a 6.6
Intron A 6.6
Leukine 6.6
Intron A 6.5
Temodal 6.5
Sodium ascorbate 6.3
Intron A 6.2
Sesamol 6.2
Ciglitazone 5.7
Cangrelor 5.7
Lepirudin 5.6
Thymopentin 5.6
Tirapazamine 5.6
Flavopiridol 5.3
more...
Enzyme
type III restriction enzyme 9.6
MGAT 7.3
GMP reductase 7.2
fucokinase 6.7
methioninase 6.7
tyrosinase 6.6
PGE2 isomerase 6.3
chondroitinase B 6.1
DCF 6.1
GD3 synthase 6.1
MHCK 5.9
EC 4.4.1.5 5.8
protein L-isoaspartyl methyltransferase 5.7
N-acetylglucosaminyltransferase V 5.7
MEK 5.7
matrix metalloproteinase 14 5.6
nicotinamide N-methyltransferase 5.5
RGP 5.2
PNL 5.2
methylthioadenosine phosphorylase 5.2
more...
Compound
2-benzyl-1H-benzo[de]isoquinoline-1,3(2H)-dione 12.0
8-hydroxy-1,3,6-naphthalenetrisulfonic acid 12.0
3-hydroxyphenylalanine 9.8
3-hydroxyphenylalanine 9.8
3-hydroxyphenylalanine 9.8
3-hydroxyphenylalanine 9.8
methyl dihydrogen phosphate 9.2
Petasin 8.7
2-iodobenzamide 8.7
4-ethoxyphenol 8.6
2,4,6-octatrienoic acid 8.4
Pectolinarigenin 8.3
1-bromoheptane 8.3
Visnagin 8.3
PGF2beta 8.3
Apogossypol 8.2
Biflorin 8.2
DHICA 8.1
Digitoxigenin 8.1
2-Thiouracil 7.9
more...