Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1522102 (
Melanoma
)
7,698
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
BRAF
600
Sep
346
Mol
231
tyrosinase
223
MEK
203
interferon
161
cytokine
156
p53
150
NRAS
144
MAPK
120
nodal
117
ERK
105
IFN
104
AKT
103
interleukin-2
98
CDKN2A
96
caspase-3
94
CD8
93
PI3K
90
PD-1
88
more...
Disease
Melanoma
7698
melanoma
7697
cancer
2370
tumor
2074
metastases
1122
metastatic melanoma
912
skin cancer
865
cutaneous melanoma
514
mole
381
tumor growth
274
tumor progression
177
uveal melanoma
168
mole
164
tumorigenesis
154
brain metastases
147
primary tumor
120
vitiligo
97
carcinoma
86
breast cancer
82
stage IV melanoma
79
more...
Symptom
fatigue
34
pain
33
nausea
20
diarrhea
20
vomiting
18
erythema
14
anesthesia
13
headache
12
abdominal pain
10
nausea and vomiting
9
starvation
8
seizures
8
dyspnea
7
anorexia
7
weakness
7
constipation
5
arthralgia
5
paresthesia
4
ataxia
4
myalgia
4
more...
Drug
Dermatol
325
IL-2
44
Ipilimumab
31
IFN-gamma
26
ROS
24
CSF
22
lysine
17
Retinoic acid
12
Fotemustine
11
L-tyrosine
9
p75
9
ROC
8
MAP
8
Paraffin
8
ascorbate
7
NADH
6
IFN-beta
6
Monit
5
Leaf
5
Gelatin
5
more...
Enzyme
mitogen-activated protein kinase
281
ERK
265
MEK
224
tyrosinase
212
caspase-3
74
lactate dehydrogenase
69
protein kinase
63
focal adhesion kinase
53
reverse transcriptase
47
luciferase
45
protein kinase C
42
PARP
33
DCF
32
caspase-9
19
urokinase-type plasminogen activator
18
catalase
17
proteasome
15
superoxide dismutase
14
glutathione S-transferase
13
AMP-activated protein kinase
13
more...
Compound
Dec
651
DNA
440
Clin
225
MEK
203
oxygen
151
tyrosine
98
DIC
67
MTT
55
cysteine
43
calcium
41
retinoic acid
39
sodium
37
methionine
37
cAMP
37
TNF
37
glucose
31
serine
30
arginine
30
vitamin D
27
GD3
26
more...