Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1522084 (Osteosarcoma)
 2,200 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
deleted in lung and esophageal cancer protein 1 13.8
HIST1H2AI 13.8
KIAA0427 13.8
SRGAP2 protein 12.8
transmembrane protein 35 12.8
wingless-type MMTV integration site family, member 5B 12.8
EIF4G2 protein 12.8
VMO1 12.8
C3orf35 12.8
ANKMY1 12.8
FAM45A 12.8
mitogen-activated protein kinase kinase kinase 9 12.2
GTF2A2 12.2
SNRNP25 12.2
KRTAP10-1 12.2
kin of IRRE like 12.2
ZNF343 12.2
LCRMP 11.8
brain-specific angiogenesis inhibitor 2 11.8
receptor (TNFRSF)-interacting serine-threonine kinase 1 11.8
KRTCAP3 11.8
PRPSAP2 11.8
TP53RK 11.7
WW domain-containing protein 1 11.5
FATE1 11.5
Actin-like protein 11.5
Ribosomal protein S9 11.2
ZNRF2 11.2
ARPC5L 11.2
distal-less homeobox 6 11.0
BTNL9 11.0
cerebellin 4 11.0
LIN28B protein 11.0
BZW1 11.0
MMS19L 11.0
Cytoskeleton-associated protein 2 11.0
Receptor tyrosine kinase-like orphan receptor 2 11.0
Neurensin-2 11.0
SEZ-6 11.0
phosphatase and tensin homolog pseudogene 1 10.8
chromobox homolog 4 10.8
transmembrane protein 119 10.8
DNALI1 10.8
LIM domain kinase 2 10.8
Nuclear apoptosis-inducing factor 1 10.8
HOS 10.7
tribbles homolog 2 10.7
DDX56 10.7
sine oculis homeobox homolog 1 10.7
RICH2 10.7
TUBA1B 10.7
MIRK 10.7
DNAH8 10.7
NOLA2 10.7
TUT1 10.7
IGSF3 10.5
ABCA10 10.5
osteosarcoma 10.5
GRM4 10.4
WDR66 10.4
SLC25A10 10.4
CDKL3 10.4
DDX10 10.4
APPBP2 10.4
FER1L4 10.4
RBEL1 10.4
HMG-box transcription factor 1 10.2
interleukin-11 receptor 10.2
p53DINP1 10.2
MAPK7 10.2
IRX2 10.2
KIAA1429 10.1
RASGRP3 10.0
PIK3R5 10.0
LY9 10.0
GNRH2 10.0
RAB3D 10.0
RAB31 10.0
MNAT1 10.0
keratinocyte differentiation-associated protein 10.0
E6TP1 10.0
antioxidant protein 1 10.0
TRIP-Br2 9.9
GCIP 9.8
APCDD1 9.8
phosphoenolpyruvate carboxykinase 2 9.8
COPS3 9.8
EIF4G2 9.8
calponin 3 9.7
BHMT2 9.7
KCNMB4 9.7
TRIM46 9.7
TOP3A 9.7
ubiquitin-specific protease 1 9.7
CMTM8 9.7
M6A 9.7
annexin A10 9.6
RAB13 9.6
PGM5 9.6
LRRC4 9.5
TP53I3 9.5
RNA-binding protein AUF1 9.5
PARP12 9.5
GNB2 9.5
thioredoxin reductase 2 9.5
KIF18B 9.4
BOG 9.4
CLSTN2 9.4
DRG1 9.4
PRMT9 9.4
formin-like 1 9.4
MDGA1 9.4
ATG4A 9.4
DGK-zeta 9.4
Midori 9.4
MED19 9.4
KPNA3 9.3
PYGB 9.3
MTX2 9.3
fibulin-like extracellular matrix protein 9.3
OSTERIX 9.3
Hepatocyte growth factor receptor 9.3
cell division cycle 20 9.3
WASF3 9.3
USP47 9.2
MMP28 9.2
FBLN 9.2
CDCA5 9.2
septin 2 9.2
Insulin-like growth factor binding protein 3 9.2
small nucleolar RNA host gene 12 9.2
RUNX2 protein 9.2
GPR177 9.2
myeloid cell nuclear differentiation antigen 9.2
PKMYT1 9.2
HNRNPL 9.2
SRGAP2 9.2
actopaxin 9.2
MAP3K5 9.1
TERF1 9.1
HNF4G 9.1
RAC2 9.1
DIF-3 9.1
AMOT 9.1
NME2 9.1
Serine/threonine protein phosphatase 9.1
ADAMTS7 9.1
EPB41 9.0
BVES 9.0
Calpain-2 9.0
RPL8 9.0
PFKFB2 9.0
YTHDF3 9.0
DLG2 9.0
PIK3IP1 9.0
Cyr61 protein 9.0
chemokine (C-C motif) ligand 3 9.0
TRA2B 9.0
SF3a66 9.0
WNT7B 9.0
more...
Disease
Osteosarcoma 13.8
Osteosarcoma 13.8
dermoid inclusion 11.5
bone cancer 11.5
localized osteosarcoma 11.4
metastatic osteosarcoma 11.4
recurrent osteosarcoma 11.3
Intracortical osteosarcoma 11.2
Cardiac neoplasms 11.2
chondroblastic osteosarcoma 11.0
fibroblastic osteosarcoma 10.9
osteosarcoma 10.9
osteoblastic osteosarcoma 10.6
Malignant Peripheral Nerve Sheath Tumor 10.5
Periosteal chondrosarcoma 10.4
HOS 10.3
bone neoplasm 10.2
anaplastic osteosarcoma 10.0
Small cell osteosarcoma 9.8
Undifferentiated sarcoma 9.8
telangiectatic osteosarcoma 9.8
Medullary Thyroid Carcinoma 9.3
skeletal neoplasm 9.2
Chloroma 8.9
Extraskeletal osteosarcoma 8.8
Chondrosarcoma 8.6
Chondrosarcoma 8.6
Parosteal osteosarcoma 8.5
Hand-Schuller-Christian disease 8.3
Fibrous dysplasia of bone 8.2
Spermatic cord 8.2
congenital amegakaryocytic thrombocytopenia 8.1
Bone sarcomas 8.0
carcinoma of unknown origin 7.7
Sarcoma 7.6
Sarcoma 7.6
Ewing's sarcoma 7.5
lung metastases 7.3
AS1 7.3
Fibrous dysplasia 7.3
GIN 7.2
chondrosarcoma 7.2
Li-Fraumeni syndrome 7.2
Recurrent tumor 7.1
cementoma 7.1
RTS 7.0
pediatric solid tumor 6.9
Silence 6.6
Giant cell tumor 6.5
osteochondroma 6.5
MEST 6.5
pathological fracture 6.4
Fibrosarcoma 6.4
carcinoma of the parotid 6.4
neurofibrosarcoma 6.3
chondroma 6.2
PNET 6.2
familial cancer 6.2
chloroma 6.1
RP11 6.1
BCD 6.0
sarcoma 5.9
primary tumor 5.9
mesenchymoma 5.9
periostitis 5.8
radiation carcinogenesis 5.8
hemangiosarcoma 5.8
osteoma 5.8
SOST 5.7
malignant fibrous histiocytoma 5.6
BPP 5.6
enchondromatosis 5.6
Osteoid osteoma 5.6
second cancer 5.6
Giant cell tumor of bone 5.6
CNS metastases 5.6
orphan disease 5.6
EMT 5.5
Rhabdomyosarcoma 5.5
metastases 5.5
tumor initiation 5.5
Liposarcoma 5.5
childhood cancer 5.5
malignant state 5.4
epulis 5.4
PNET 5.3
OSX 5.3
tumor growth 5.3
uterine leiomyosarcoma 5.2
aggressiveness 5.2
retinoblastoma 5.2
enchondroma 5.2
Pelvis 5.2
RP1 5.1
DDP 5.1
tumorigenesis 5.1
fibroma 5.0
Malignant peripheral nerve sheath tumor 5.0
bone metastases 5.0
rhabdomyosarcoma 4.9
Angiosarcoma 4.9
monoarthritis 4.8
PARK2 4.8
tumor progression 4.8
Leiomyosarcoma 4.8
tumor 4.8
odontoma 4.8
chondroblastoma 4.8
MTS 4.7
epiphysis 4.7
chondromatosis 4.7
PDB 4.7
villonodular synovitis 4.7
chordoma 4.7
primitive neuroectodermal tumor 4.5
Ovarian Cancer 4.5
moderate mental retardation 4.5
hemangioendothelioma 4.5
ATRX 4.5
Hurler 4.4
Schwannoma 4.3
Schwannoma 4.3
phyllodes tumor 4.3
RP4 4.3
hemangiopericytoma 4.3
WRN 4.3
gliosarcoma 4.3
MCS 4.3
fibrosarcoma 4.3
MCS 4.3
bone disease 4.3
TCD 4.3
residual cancer 4.3
Medulloblastoma 4.2
recurrent breast cancer 4.2
primitive neuroectodermal tumor 4.2
anaplastic thyroid cancer 4.2
Neoplasms 4.2
embryonal rhabdomyosarcoma 4.2
measurable disease 4.1
solid tumor 4.1
DSS 4.1
Parathyroid 4.1
cancer recurrence 4.1
osteosclerosis 4.0
odontogenic tumor 4.0
ABS 4.0
Malignant transformation 4.0
rare disease 4.0
osteogenesis imperfecta 4.0
MEN1 4.0
Leber's hereditary optic neuropathy 4.0
cancer 3.9
intussusception 3.9
ABS 3.9
periosteum 3.9
BLM 3.8
angiosarcoma 3.8
TAS 3.8
synovial sarcoma 3.8
more...
Symptom
thigh pain 5.4
Scratch 5.2
Spots 5.0
heel pain 4.9
bone pain 4.5
cancer pain 4.2
dry skin 3.8
hip pain 3.0
leg pain 2.8
distraction 2.6
dysuria 2.6
knee pain 2.4
cyanosis 1.9
neck pain 1.9
low back pain 1.5
numbness 1.5
dyspnea 1.4
paresis 1.3
pain 1.1
regurgitation 0.8
starvation 0.8
syncope 0.6
nausea and vomiting 0.6
agitation 0.3
functional recovery 0.1
headache 0.0
vomiting -0.1
chest pain -0.3
hypothermia -0.3
diarrhea -0.4
anesthesia -0.6
discomfort -0.6
nausea -0.7
cough -0.7
discomfort -0.8
collapse -1.0
abdominal pain -1.1
fatigue -1.8
seizures -2.5
Drug
Mifamurtide 11.5
Molgramostim 11.2
2-Methoxyestradiol 8.0
Hydroxypropyl cellulose 8.0
Cilengitide 7.7
Valproic Acid 7.3
Trabectedin 6.6
Aprepitant 6.6
Auranofin 6.4
Tranilast 6.1
GEO 6.0
NVP 5.9
Anakinra 5.8
Zoledronic acid 5.8
Propidium 5.8
Zoledronic acid 5.8
Denosumab 5.7
Etoposide 5.7
Zein 5.7
Bestatin 5.7
Filgrastim 5.4
Filgrastim 5.2
PFT 4.9
EHDP 4.9
Leucovorin 4.8
IL-11 4.7
Adriamycin 4.6
PDL 4.5
Everolimus 4.4
Gleevec 4.3
Simvastatin 4.1
Cetuximab 3.9
ADR 3.8
ADM 3.8
uPA 3.8
Doxycycline 3.7
CDP 3.6
ROS 3.6
Arsenic trioxide 3.5
ETS 3.5
BLM 3.4
IL-1ra 3.4
Bortezomib 3.3
Sorafenib 3.3
Monit 3.2
Activin 3.1
Gelatin 3.1
Docetaxel 3.0
ROC 2.9
ACT 2.7
Imatinib 2.5
Alliance 2.4
Fluorescein 2.4
ALA 2.4
Indomethacin 2.2
MRC 2.1
HCH 2.1
Kenyan 2.1
Fluorescein 1.9
ABC 1.7
G-CSF 1.5
CTX 1.4
CTX 1.3
MAP 0.9
CTX 0.5
caffeine 0.4
TiO2 0.4
lysine -0.0
CSF -0.1
ascorbate -0.7
IFN-gamma -1.0
Cardiovasc -2.8
Dermatol -4.2
Enzyme
cathepsin F 7.8
phosphatidylinositol-4,5-bisphosphate 3-kinase 7.2
nicotinamide mononucleotide adenylyltransferase 6.8
stromelysin-3 6.8
KLK7 6.3
branched-chain aminotransferase 6.0
inositol 3-kinase 6.0
matrix metalloproteinase 2 5.6
luciferase 5.5
alginate lyase 5.3
GLO 5.2
Protein 2 5.1
matrix metalloproteinase 9 5.0
PARP 5.0
caspase-9 4.9
caspase-6 4.9
caspase-3 4.9
caspase-6 4.9
O-GlcNAc transferase 4.9
MMP 4.6
prostaglandin synthetase 4.6
MEKK1 4.5
caspase-8 4.5
enterokinase 4.4
GSK 4.4
methionine adenosyltransferase 4.4
ornithine aminotransferase 4.3
MEK 4.3
phosphatidylinositol 3-kinase 4.3
polo-like kinase 1 4.2
MCS 4.2
ALDH 4.0
MDP 4.0
cathepsin K 4.0
phosphoinositide 3-kinase 3.9
bromelain 3.8
mitogen-activated protein kinase 3.8
5'-nucleotidase 3.8
PDK1 3.7
MMP-3 3.7
ERK 3.6
focal adhesion kinase 3.6
alkaline phosphatase 3.5
11beta-hydroxysteroid dehydrogenase 3.5
cdc2 3.4
firefly luciferase 3.4
aldehyde dehydrogenase 3.3
aldehyde dehydrogenase 3.3
aldehyde dehydrogenase 3.3
protein phosphatase 2A 3.3
AMPK 3.2
AMP-activated protein kinase 3.1
granzyme B 3.1
aldehyde dehydrogenase 3.1
HSD 3.1
prostate-specific membrane antigen 3.0
proteasome 3.0
CaMKII 2.8
aldehyde dehydrogenase 2.7
topoisomerase 2.7
protein kinase 2.6
thioredoxin reductase 2.6
topoisomerase 2.5
DNA methyltransferase 2.5
thymidine kinase 2.5
P-glycoprotein 2.4
dihydrofolate reductase 2.3
complex I 2.3
collagenase 2.2
AMPK 2.2
ornithine decarboxylase 2.2
STR 2.2
APC 2.1
urokinase-type plasminogen activator 2.0
CD13 2.0
MAP 2.0
cathepsin D 1.8
cathepsin B 1.8
lactate dehydrogenase 1.8
chitinase 1.8
acid phosphatase 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.7
glyceraldehyde-3-phosphate dehydrogenase 1.7
glyceraldehyde-3-phosphate dehydrogenase 1.6
transcriptase 1.6
adenylate cyclase 1.6
transglutaminase 1.6
IKK 1.6
kinesin 1.5
CPR 1.5
hexokinase 1.5
demethylase 1.4
phosphorylase 1.4
glyceraldehyde-3-phosphate dehydrogenase 1.4
calcineurin 1.3
diaphorase 1.3
kallikrein 1.3
AST 1.3
protein kinase C 1.2
caspase-1 1.2
CYP3A4 1.2
glyceraldehyde-3-phosphate dehydrogenase 1.2
beta-glucuronidase 0.9
lipoxygenase 0.7
phospholipase C 0.6
endonuclease 0.6
glutathione reductase 0.6
reverse transcriptase 0.5
aspartate aminotransferase 0.4
chymotrypsin 0.4
glutathione S-transferase 0.4
RNA polymerase 0.3
alanine aminotransferase 0.1
trypsin 0.0
thrombin -0.2
lysozyme -0.6
ATPase -0.6
glutathione peroxidase -0.6
ACS -0.9
superoxide dismutase -1.0
catalase -1.9
peroxidase -2.2
Compound
Sennoside B 12.2
Raddeanin A 11.2
Euxanthone 10.4
Bruceine D 10.2
Picropodophyllin 10.0
Sennoside A 9.3
Tomatidine 9.2
Tomatidine 9.2
Calycosin 9.1
11-aminoundecanoic acid 9.1
MNNG 8.9
Fangchinoline 8.8
Cinobufagin 8.8
N6-Methyladenosine 8.8
Punicalagin 8.4
Berbamine 8.3
Evodiamine 8.3
SC-58125 8.2
Evodiamine 8.2
Alantolactone 8.0
2-Methoxyestradiol 8.0
Lycorine 7.8
Anethole 7.7
Glabridin 7.7
Cucurbitacin B 7.6
Escin 7.6
Escin 7.5
Deguelin 7.5
Celastrol 7.5
Calcein AM 7.4
Noscapine 7.3
Dioscin 7.3
Dioscin 7.3
Oridonin 7.1
Phenethyl isothiocyanate 7.0
Mangostin 6.9
Fisetin 6.8
dADP 6.8
BAPN 6.8
Ifosfamide 6.8
TRU 6.8
AT-101 6.8
AT-101 6.7
D-Serine 6.7
AT-101 6.7
Cerulenin 6.7
DXP 6.7
Sinomenine 6.6
Bufalin 6.6
Triptolide 6.4
CHM 6.4
celastrol 6.4
Enoxacin 6.3
Pterostilbene 6.3
Hesperetin 6.3
Clofazimine 6.1
Magnolol 6.1
Vimentin 6.1
Wogonin 6.1
Plumbagin 6.0
CH3-THF 6.0
Baicalein 5.9
Selenocysteine 5.9
Geldanamycin 5.8
INN 5.8
benzohydrazide 5.8
Oxycodone 5.8
Shikonin 5.8
MHS 5.7
Phloretin 5.6
Honokiol 5.5
Bestatin 5.5
DDP 5.4
Pimozide 5.4
TPCK 5.3
NOXA 5.3
MTT 5.2
Sulforaphane 5.2
Propidium iodide 5.2
CNA 5.2
Epirubicin 5.2
DEG 5.1
Alizarin Red S 5.1
EHDP 5.1
CAN 5.1
SP-1 5.0
5-formyltetrahydrofolate 5.0
Adriamycin 5.0
APN 4.9
Cortisone 4.9
Leucovorin 4.9
Crystal Violet 4.9
Baicalin 4.9
Busulfan 4.8
Gossypol 4.8
ADR 4.8
Gossypol 4.8
MTS 4.8
Chlorogenic acid 4.7
Gemcitabine 4.7
MTX 4.7
Gemcitabine 4.7
DAC 4.7
nonyl 4.6
T13 4.6
Carrageenan 4.6
5-Aza-2'-deoxycytidine 4.6
MEK 4.6
Etanercept 4.5
STP 4.5
Cytochrome c 4.5
PPI 4.4
DBH 4.4
ALP 4.3
Methotrexate 4.3
DAPT 4.3
RELA 4.3
PDT 4.3
Alginate 4.3
Amide 4.2
L-PAM 4.2
L-PAM 4.2
VP-16 4.2
TNM 4.2
CDP 4.2
Ether 4.1
CHIP 4.1
Ether 4.1
Okadaic acid 4.1
Dobutamine 4.0
isoquinoline 3.9
Cyt 3.9
Valproic acid 3.8
PID 3.8
PID 3.8
Doxycycline 3.8
DMD 3.7
Hoechst 33342 3.6
Belt 3.6
Glycogen synthase 3.6
Berberine 3.6
XTT 3.5
keratan sulfate 3.5
chalcone 3.5
Sphingosine 3.4
MCH 3.4
Docetaxel 3.4
Mato 3.3
Paclitaxel 3.3
HMG-CoA 3.3
ADP-ribose 3.3
Quercetin 3.2
Neo 3.1
Rapamycin 3.1
folinic acid 3.1
ubiquinol 3.1
1H-imidazole 3.0
bromide 3.0
strontium 3.0
N-acetylcysteine 3.0
more...