Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1522083 (
Osteosarcoma
)
2,200
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
osteosarcoma
1448
Mol
175
Sep
120
p53
117
HOS
96
caspase-3
91
catenin
76
AKT
72
PI3K
68
Bcl-2
50
mTOR
46
osteogenic
39
alkaline phosphatase
38
matrix metalloproteinase
38
MMP-2
37
p21
35
E-cadherin
34
UTR
34
ERK
34
MAPK
33
MMP-9
33
p38
31
PARP
30
pRb
30
STAT3
27
MMP9
26
kit
26
cyclin D1
26
collagen
26
ERK1
25
VEGF
24
CCK
24
vascular endothelial growth factor
24
JNK
24
caspase-9
23
cytokine
22
MEK
22
annexin V
21
vimentin
21
osteocalcin
20
AS1
20
RUNX2
20
CXCR4
17
c-Myc
17
proteasome
16
MDM2
16
c-Jun
16
fibronectin
16
proliferating cell nuclear antigen
16
epidermal growth factor receptor
16
ROS
16
MMP2
15
phosphatidylinositol 3-kinase
15
Cyclin D1
15
N-cadherin
14
PTEN
13
Rho
13
osteopontin
13
chemokine
13
MYC
13
endoplasmic reticulum
13
p65
13
scratch
12
rhabdomyosarcoma
12
insulin
12
RB1
12
MRI
12
EGFR
12
Vimentin
12
ezrin
11
RANKL
11
TNF
11
AP-1
11
RhoA
11
p27
11
c-myc
11
caspase-8
11
Ki-67
11
histone
10
phosphatase
10
more...
Disease
osteosarcoma
2200
Osteosarcoma
2200
Osteosarcoma
2200
tumor
1321
cancer
1155
metastases
323
bone cancer
207
tumor growth
158
tumorigenesis
137
sarcoma
108
HOS
96
primary tumor
83
tumor progression
79
metastatic osteosarcoma
62
Ewing's sarcoma
61
lung metastases
59
chondrosarcoma
45
carcinogenesis
38
carcinoma
31
aggressiveness
31
retinoblastoma
28
Sarcoma
25
Sarcoma
25
osteoblastic osteosarcoma
23
AS1
20
bone neoplasm
19
leukemia
18
dysplasia
17
chondroblastic osteosarcoma
15
rare disease
14
multiple myeloma
14
bone metastases
14
DDP
13
childhood cancer
13
breast cancer
13
rhabdomyosarcoma
13
aggression
12
PDB
12
Chondrosarcoma
12
Chondrosarcoma
12
B-cell lymphoma
11
tumor initiation
11
osteoporosis
10
bone disease
10
pathological fracture
10
Li-Fraumeni syndrome
10
fibrosarcoma
10
localized osteosarcoma
10
solid tumor
9
malignant fibrous histiocytoma
9
EMT
9
melanoma
9
colon cancer
9
prostate cancer
9
recurrent osteosarcoma
8
osteoma
8
osteochondroma
8
GSH
8
neuroblastoma
8
RTS
7
lymphoma
7
fibroma
7
epiphysis
7
fibroblastic osteosarcoma
6
ovarian cancer
6
Blocking
6
SCID
6
cold
6
WT1
6
non-small cell lung cancer
6
infectious diseases
6
MTS
5
telangiectatic osteosarcoma
5
ATM
5
adenocarcinoma
5
APC
5
Still
4
angiosarcoma
4
familial cancer
4
intussusception
4
more...
Symptom
pain
39
anesthesia
5
dyspnea
5
bone pain
5
cancer pain
4
headache
4
distraction
4
diarrhea
3
starvation
3
low back pain
2
vomiting
2
thigh pain
2
leg pain
1
agitation
1
paresis
1
cough
1
regurgitation
1
cyanosis
1
fatigue
1
hip pain
1
nausea
1
knee pain
1
Scratch
1
dry skin
1
abdominal pain
1
discomfort
1
heel pain
1
numbness
1
functional recovery
1
nausea and vomiting
1
discomfort
1
chest pain
1
Spots
1
neck pain
1
collapse
1
hypothermia
1
syncope
1
seizures
1
dysuria
1
Drug
Monit
23
ROS
16
Adriamycin
8
GEO
7
Etoposide
4
ROC
4
lysine
4
NVP
4
ADM
3
2-Methoxyestradiol
3
Zoledronic acid
3
Auranofin
2
ADR
2
MAP
2
Cardiovasc
2
Denosumab
2
ABC
2
uPA
2
Zoledronic acid
2
Indomethacin
2
ETS
2
IL-11
2
Simvastatin
2
Mifamurtide
2
CSF
2
Gleevec
2
caffeine
2
CDP
2
Kenyan
1
G-CSF
1
Valproic Acid
1
Zein
1
Dermatol
1
Leucovorin
1
CTX
1
MRC
1
Arsenic trioxide
1
Cetuximab
1
Propidium
1
Molgramostim
1
BLM
1
Filgrastim
1
EHDP
1
Docetaxel
1
PFT
1
IL-1ra
1
Filgrastim
1
TiO2
1
Doxycycline
1
CTX
1
CTX
1
ACT
1
ascorbate
1
Fluorescein
1
IFN-gamma
1
Sorafenib
1
Alliance
1
Bestatin
1
Tranilast
1
Activin
1
Gelatin
1
Imatinib
1
Trabectedin
1
PDL
1
Everolimus
1
Anakinra
1
Cilengitide
1
Fluorescein
1
Hydroxypropyl cellulose
1
HCH
1
Bortezomib
1
Aprepitant
1
ALA
1
Enzyme
luciferase
121
mitogen-activated protein kinase
92
ERK
81
caspase-3
74
alkaline phosphatase
38
focal adhesion kinase
36
protein kinase
34
PARP
30
MEK
25
caspase-9
16
proteasome
16
phosphatidylinositol 3-kinase
15
caspase-8
11
GSK
10
matrix metalloproteinase 2
8
AMP-activated protein kinase
8
protein kinase C
8
MMP
7
lactate dehydrogenase
7
phosphoinositide 3-kinase
6
cdc2
6
collagenase
6
P-glycoprotein
5
APC
5
matrix metalloproteinase 9
5
AMPK
4
topoisomerase
4
topoisomerase
4
AMPK
4
adenylate cyclase
4
acid phosphatase
3
RNA polymerase
3
aldehyde dehydrogenase
3
aldehyde dehydrogenase
3
aldehyde dehydrogenase
3
prostaglandin synthetase
3
urokinase-type plasminogen activator
3
trypsin
3
thymidine kinase
3
aldehyde dehydrogenase
3
MDP
3
complex I
3
MEKK1
3
MMP-3
3
calcineurin
3
ACS
3
5'-nucleotidase
3
reverse transcriptase
3
ATPase
3
aldehyde dehydrogenase
3
alanine aminotransferase
2
protein phosphatase 2A
2
thrombin
2
glutathione S-transferase
2
cathepsin K
2
endonuclease
2
dihydrofolate reductase
2
firefly luciferase
2
CaMKII
2
transcriptase
2
HSD
2
PDK1
2
polo-like kinase 1
2
phosphatidylinositol-4,5-bisphosphate 3-kinase
2
aspartate aminotransferase
2
ornithine decarboxylase
2
phospholipase C
2
granzyme B
2
MAP
2
DNA methyltransferase
2
superoxide dismutase
2
glyceraldehyde-3-phosphate dehydrogenase
1
glyceraldehyde-3-phosphate dehydrogenase
1
kinesin
1
chitinase
1
methionine adenosyltransferase
1
MCS
1
AST
1
GLO
1
beta-glucuronidase
1
more...
Compound
Dec
151
DNA
122
Clin
113
MTT
85
oxygen
58
calcium
36
bromide
24
MNNG
23
DDP
22
MEK
21
Adriamycin
18
phosphate
14
methionine
13
ADR
12
Vimentin
12
TNF
11
tyrosine
10
nitrogen
10
TNM
10
serine
10
Pac
10
glucose
9
iodine
8
GSH
8
PEG
8
GSH
8
cysteine
7
threonine
7
Methotrexate
7
PEG
7
formaldehyde
6
ALP
6
ATP
6
Insulin
6
N-acetylcysteine
6
lysine
5
ASA
5
MTS
5
sodium
5
boron
5
Celastrol
4
Panam
4
carbonate
4
celastrol
4
retinoic acid
4
Ifosfamide
4
ethyl acetate
4
selenium
4
VP-16
4
GTP
4
MTX
4
ADP-ribose
4
water
4
titanium
4
PGE2
4
Cytochrome c
3
ACS
3
potassium
3
Gemcitabine
3
TOF
3
Triptolide
3
fluorine
3
Lactate
3
Evodiamine
3
PPI
3
TEM
3
Gemcitabine
3
NAD
3
phosphorus
3
adenosylmethionine
3
isoquinoline
3
Melatonin
3
ethanol
3
tryptophan
3
ACS
3
iron
3
NAD
3
Calycosin
3
leucine
3
Evodiamine
3
more...