Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1519670 (tumor angiogenesis)
6,052 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
vascular endothelial growth factor 1329
VEGF 674
Mol 498
Sep 391
VEGFR2 322
Vascular endothelial growth factor 279
CD31 237
tyrosine kinase 198
cytokine 181
vascular endothelial growth factor A 180
CD34 161
p53 153
AKT 151
vascular endothelial growth factor receptor 137
mTOR 125
PI3K 105
VEGFR-1 100
collagen 99
endostatin 99
matrix metalloproteinase 97
KDR 88
IL-8 88
ERK 85
platelet-derived 83
vascular endothelial growth factor receptor 2 82
receptor tyrosine kinase 81
MMP-9 80
MMP-2 79
vascular endothelium 78
STAT3 77
ERK1 75
MRI 75
platelet-derived growth factor 74
Bcl-2 74
chemokine 72
cage 69
epidermal growth factor receptor 67
fibronectin 67
HIF-1alpha 65
MAPK 62
p38 61
cyclooxygenase-2 59
caspase-3 59
thrombospondin 57
factor VIII 57
hepatocyte growth factor 56
CD105 56
FGF 56
CXCR4 55
extracellular signal-regulated kinase 54
tumor necrosis factor 53
COX-2 51
IL-6 50
bFGF 50
placental growth factor 47
EGFR 47
TNF 46
VEGF-C 46
CD8 46
epidermal growth factor 45
HIF-1 45
PDGF 43
tissue factor 43
CXCL12 42
urokinase-type plasminogen activator 42
plasminogen 42
colon carcinoma 40
MEK 39
vitronectin 39
osteosarcoma 39
glycoprotein 38
neuropilin-1 38
Tie-2 38
phosphatidylinositol 3-kinase 38
focal adhesion kinase 38
angiopoietin-1 38
E-cadherin 38
angiogenin 37
heparanase 37
JNK 36
more...
Disease
tumor angiogenesis 6052
tumor 4239
cancer 3347
tumor growth 1694
tumor progression 709
breast cancer 505
carcinoma 393
metastases 361
tumorigenesis 331
melanoma 296
tumor vasculature 277
hepatocellular carcinoma 249
colorectal cancer 220
carcinogenesis 203
lung cancer 197
prostate cancer 180
glioma 176
adenocarcinoma 154
glioblastoma 146
squamous cell carcinoma 139
renal cell carcinoma 127
lung carcinoma 124
colon cancer 120
non-small cell lung cancer 117
primary tumor 109
ovarian cancer 105
gastric cancer 102
pancreatic cancer 101
solid tumor 99
MCF 67
aggressiveness 64
brain tumor 60
epithelial ovarian cancer 54
fibrosarcoma 50
ischemia 50
Hippel 47
liver cancer 46
SCID 46
sarcoma 44
glioblastoma multiforme 44
cervical cancer 42
lung metastases 42
bladder cancer 39
osteosarcoma 39
atherosclerosis 39
multiple myeloma 38
lymphoma 37
neuroblastoma 37
mammary tumor 36
lymphatic vessels 35
leukemia 35
Hepatocellular carcinoma 35
hypertension 35
mimicry 33
cornea 32
liver cancer 31
renal cancer 29
tumor initiation 29
Blocking 28
Glioblastoma 27
liver metastases 25
metastatic breast cancer 25
Kaposi's sarcoma 25
rheumatoid arthritis 24
Melanoma 22
obesity 22
adenoma 21
diabetes 21
HGF 21
endometrial cancer 21
suicide 19
retinopathy 19
head and neck cancer 18
oral cancer 17
metastatic renal cell carcinoma 17
arthritis 17
acute myeloid leukemia 17
sepsis 16
EMT 16
sepsis 16
more...
Symptom
pain 14
starvation 14
diarrhea 10
collapse 7
nausea 7
fatigue 6
cachexia 5
vomiting 4
anesthesia 4
hypercapnia 4
seizures 4
hemoptysis 3
headache 3
hyperoxia 2
analgesia 2
overweight 2
asthenia 2
night sweats 1
ataxia 1
rigors 1
erythema 1
splenomegaly 1
Scratch 1
dyspnea 1
rundown 1
dry skin 1
pelvic pain 1
apathy 1
constipation 1
exhaustion 1
rhinorrhea 1
thinning 1
sneezing 1
flushing 1
functional recovery 1
skin damage 1
acidity 1
anorexia 1
skin irritation 1
cancer pain 1
productive cough 1
decreased appetite 1
chills 1
weakness 1
respiratory distress 1
Flu-like symptoms 1
hepatosplenomegaly 1
nausea and vomiting 1
Drug
Bevacizumab 86
Sorafenib 29
IFN-gamma 22
lysine 21
Dermatol 19
CSF 16
ROS 15
Cardiovasc 15
Paraffin 13
CAM 12
uPA 10
IL-2 9
Monit 9
MAP 8
vitamin E 7
Imatinib 6
CoCl2 6
CoCl2 6
Cetuximab 5
Arsenic trioxide 5
Gleevec 5
G-CSF 5
Gefitinib 5
NADH 5
CTX 5
Docetaxel 5
Taxol 5
ICI 4
Gel 4
Irinotecan 4
Bortezomib 4
RFP 4
Cilengitide 4
Gelatin 4
Activin 4
Adriamycin 4
2-Methoxyestradiol 4
BH4 4
Erlotinib 4
Retinoic acid 4
Nexavar 4
Lovastatin 3
CTT 3
Herceptin 3
Taxotere 3
Axitinib 3
Vandetanib 3
p75 3
TAT 3
Arresten 3
Indomethacin 3
ETS 3
Tarceva 3
TAK 3
Fragment 3
IFN-beta 3
Prednisolone 2
DMSA 2
Pemetrexed 2
Bestatin 2
KGF 2
EE2 2
GEO 2
Doxycycline 2
Gelfoam 2
Marimastat 2
CTX 2
Simvastatin 2
Semaxanib 2
Sunitinib malate 2
Albumin 2
Estrogens 2
Oxaliplatin 2
CTX 2
CPT-11 2
Azithromycin 2
Serum albumin 2
Optison 2
Optison 2
lactose 2
more...
Enzyme
ERK 486
mitogen-activated protein kinase 249
focal adhesion kinase 109
luciferase 63
protein kinase 62
MEK 54
urokinase-type plasminogen activator 49
caspase-3 48
phosphatidylinositol 3-kinase 38
proteasome 34
protein kinase C 30
thrombin 29
phosphoinositide 3-kinase 25
thymidine phosphorylase 24
MMP 24
ACS 22
trypsin 22
CD13 20
PARP 20
plasmin 18
collagenase 18
tryptase 16
matrix metalloproteinase 9 14
AMP-activated protein kinase 13
cathepsin B 12
reverse transcriptase 12
AMPK 11
RNase 11
RNase 11
prolyl hydroxylase 10
AMPK 10
GSK 10
caspase-9 9
thymidine kinase 9
TSP-1 9
MMP-3 9
tissue plasminogen activator 9
NADPH oxidase 9
NADPH oxidase 9
caspase-8 8
RNA polymerase 8
ribonuclease 8
matrix metalloproteinase 2 8
MAP 8
ribonuclease 8
catalase 8
peroxidase 8
P-glycoprotein 7
NO synthase 7
cdc2 7
alkaline phosphatase 7
APC 7
renin 7
hyaluronidase 6
phospholipase C 6
beta-galactosidase 6
lipoxygenase 6
hyaluronidase 6
calcineurin 6
ATP synthase 5
PDK1 5
prostate-specific antigen 5
NOS 5
12-lipoxygenase 5
transcriptase 5
IKK 4
pyruvate kinase 4
DNA methyltransferase 4
cathepsin D 4
superoxide dismutase 4
ATPase 4
complex I 4
prostate-specific membrane antigen 4
kallikrein 3
glutathione peroxidase 3
TAT 3
lactate dehydrogenase 3
indoleamine 2,3-dioxygenase 3
SPC 3
PAM 3
more...
Compound
Dec 422
Clin 257
oxygen 253
DNA 223
tyrosine 190
MDA 118
arginine 73
water 62
sulfate 50
nitric oxide 49
Asp 47
TNF 46
phosphate 45
MTT 42
glucose 40
MEK 39
methionine 39
PEG 39
calcium 35
cysteine 33
ATP 32
PEG 32
serine 30
Gly 30
iron 27
lysine 26
TNM 26
leucine 25
ethanol 24
copper 24
acetate 24
ACS 23
ACS 22
sodium 21
ASA 19
hydrogen 18
PGE2 17
His 17
aspartic acid 17
aspartic acid 17
aspartic acid 17
aspartic acid 17
threonine 16
iodine 15
alanine 15
CAM 14
SCC 13
nitrogen 13
5-FU 13
cAMP 12
urea 12
bromide 12
zinc 11
SDS 11
H2O2 11
galactose 11
Sphingosine 11
PMA 10
AMP 10
Neo 10
pyrimidine 10
pyrimidine 10
Phe 9
Heparin 9
DTPA 9
cobalt 9
selenium 9
NH2 9
APN 9
Adriamycin 9
MAP 8
Curcumin 8
dUTP 8
cGMP 7
Rapamycin 7
proline 7
quinoline 7
COS 7
anthracene 7
DDP 7
more...