Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1519670 (
tumor angiogenesis
)
6,052
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
vascular endothelial growth factor
1329
VEGF
674
Mol
498
Sep
391
VEGFR2
322
Vascular endothelial growth factor
279
CD31
237
tyrosine kinase
198
cytokine
181
vascular endothelial growth factor A
180
CD34
161
p53
153
AKT
151
vascular endothelial growth factor receptor
137
mTOR
125
PI3K
105
VEGFR-1
100
collagen
99
endostatin
99
matrix metalloproteinase
97
KDR
88
IL-8
88
ERK
85
platelet-derived
83
vascular endothelial growth factor receptor 2
82
receptor tyrosine kinase
81
MMP-9
80
MMP-2
79
vascular endothelium
78
STAT3
77
ERK1
75
MRI
75
platelet-derived growth factor
74
Bcl-2
74
chemokine
72
cage
69
epidermal growth factor receptor
67
fibronectin
67
HIF-1alpha
65
MAPK
62
p38
61
cyclooxygenase-2
59
caspase-3
59
thrombospondin
57
factor VIII
57
hepatocyte growth factor
56
CD105
56
FGF
56
CXCR4
55
extracellular signal-regulated kinase
54
tumor necrosis factor
53
COX-2
51
IL-6
50
bFGF
50
placental growth factor
47
EGFR
47
TNF
46
VEGF-C
46
CD8
46
epidermal growth factor
45
HIF-1
45
PDGF
43
tissue factor
43
CXCL12
42
urokinase-type plasminogen activator
42
plasminogen
42
colon carcinoma
40
MEK
39
vitronectin
39
osteosarcoma
39
glycoprotein
38
neuropilin-1
38
Tie-2
38
phosphatidylinositol 3-kinase
38
focal adhesion kinase
38
angiopoietin-1
38
E-cadherin
38
angiogenin
37
heparanase
37
JNK
36
more...
Disease
tumor angiogenesis
6052
tumor
4239
cancer
3347
tumor growth
1694
tumor progression
709
breast cancer
505
carcinoma
393
metastases
361
tumorigenesis
331
melanoma
296
tumor vasculature
277
hepatocellular carcinoma
249
colorectal cancer
220
carcinogenesis
203
lung cancer
197
prostate cancer
180
glioma
176
adenocarcinoma
154
glioblastoma
146
squamous cell carcinoma
139
renal cell carcinoma
127
lung carcinoma
124
colon cancer
120
non-small cell lung cancer
117
primary tumor
109
ovarian cancer
105
gastric cancer
102
pancreatic cancer
101
solid tumor
99
MCF
67
aggressiveness
64
brain tumor
60
epithelial ovarian cancer
54
fibrosarcoma
50
ischemia
50
Hippel
47
liver cancer
46
SCID
46
sarcoma
44
glioblastoma multiforme
44
cervical cancer
42
lung metastases
42
bladder cancer
39
osteosarcoma
39
atherosclerosis
39
multiple myeloma
38
lymphoma
37
neuroblastoma
37
mammary tumor
36
lymphatic vessels
35
leukemia
35
Hepatocellular carcinoma
35
hypertension
35
mimicry
33
cornea
32
liver cancer
31
renal cancer
29
tumor initiation
29
Blocking
28
Glioblastoma
27
liver metastases
25
metastatic breast cancer
25
Kaposi's sarcoma
25
rheumatoid arthritis
24
Melanoma
22
obesity
22
adenoma
21
diabetes
21
HGF
21
endometrial cancer
21
suicide
19
retinopathy
19
head and neck cancer
18
oral cancer
17
metastatic renal cell carcinoma
17
arthritis
17
acute myeloid leukemia
17
sepsis
16
EMT
16
sepsis
16
more...
Symptom
pain
14
starvation
14
diarrhea
10
collapse
7
nausea
7
fatigue
6
cachexia
5
vomiting
4
anesthesia
4
hypercapnia
4
seizures
4
hemoptysis
3
headache
3
hyperoxia
2
analgesia
2
overweight
2
asthenia
2
night sweats
1
ataxia
1
rigors
1
erythema
1
splenomegaly
1
Scratch
1
dyspnea
1
rundown
1
dry skin
1
pelvic pain
1
apathy
1
constipation
1
exhaustion
1
rhinorrhea
1
thinning
1
sneezing
1
flushing
1
functional recovery
1
skin damage
1
acidity
1
anorexia
1
skin irritation
1
cancer pain
1
productive cough
1
decreased appetite
1
chills
1
weakness
1
respiratory distress
1
Flu-like symptoms
1
hepatosplenomegaly
1
nausea and vomiting
1
Drug
Bevacizumab
86
Sorafenib
29
IFN-gamma
22
lysine
21
Dermatol
19
CSF
16
ROS
15
Cardiovasc
15
Paraffin
13
CAM
12
uPA
10
IL-2
9
Monit
9
MAP
8
vitamin E
7
Imatinib
6
CoCl2
6
CoCl2
6
Cetuximab
5
Arsenic trioxide
5
Gleevec
5
G-CSF
5
Gefitinib
5
NADH
5
CTX
5
Docetaxel
5
Taxol
5
ICI
4
Gel
4
Irinotecan
4
Bortezomib
4
RFP
4
Cilengitide
4
Gelatin
4
Activin
4
Adriamycin
4
2-Methoxyestradiol
4
BH4
4
Erlotinib
4
Retinoic acid
4
Nexavar
4
Lovastatin
3
CTT
3
Herceptin
3
Taxotere
3
Axitinib
3
Vandetanib
3
p75
3
TAT
3
Arresten
3
Indomethacin
3
ETS
3
Tarceva
3
TAK
3
Fragment
3
IFN-beta
3
Prednisolone
2
DMSA
2
Pemetrexed
2
Bestatin
2
KGF
2
EE2
2
GEO
2
Doxycycline
2
Gelfoam
2
Marimastat
2
CTX
2
Simvastatin
2
Semaxanib
2
Sunitinib malate
2
Albumin
2
Estrogens
2
Oxaliplatin
2
CTX
2
CPT-11
2
Azithromycin
2
Serum albumin
2
Optison
2
Optison
2
lactose
2
more...
Enzyme
ERK
486
mitogen-activated protein kinase
249
focal adhesion kinase
109
luciferase
63
protein kinase
62
MEK
54
urokinase-type plasminogen activator
49
caspase-3
48
phosphatidylinositol 3-kinase
38
proteasome
34
protein kinase C
30
thrombin
29
phosphoinositide 3-kinase
25
thymidine phosphorylase
24
MMP
24
ACS
22
trypsin
22
CD13
20
PARP
20
plasmin
18
collagenase
18
tryptase
16
matrix metalloproteinase 9
14
AMP-activated protein kinase
13
cathepsin B
12
reverse transcriptase
12
AMPK
11
RNase
11
RNase
11
prolyl hydroxylase
10
AMPK
10
GSK
10
caspase-9
9
thymidine kinase
9
TSP-1
9
MMP-3
9
tissue plasminogen activator
9
NADPH oxidase
9
NADPH oxidase
9
caspase-8
8
RNA polymerase
8
ribonuclease
8
matrix metalloproteinase 2
8
MAP
8
ribonuclease
8
catalase
8
peroxidase
8
P-glycoprotein
7
NO synthase
7
cdc2
7
alkaline phosphatase
7
APC
7
renin
7
hyaluronidase
6
phospholipase C
6
beta-galactosidase
6
lipoxygenase
6
hyaluronidase
6
calcineurin
6
ATP synthase
5
PDK1
5
prostate-specific antigen
5
NOS
5
12-lipoxygenase
5
transcriptase
5
IKK
4
pyruvate kinase
4
DNA methyltransferase
4
cathepsin D
4
superoxide dismutase
4
ATPase
4
complex I
4
prostate-specific membrane antigen
4
kallikrein
3
glutathione peroxidase
3
TAT
3
lactate dehydrogenase
3
indoleamine 2,3-dioxygenase
3
SPC
3
PAM
3
more...
Compound
Dec
422
Clin
257
oxygen
253
DNA
223
tyrosine
190
MDA
118
arginine
73
water
62
sulfate
50
nitric oxide
49
Asp
47
TNF
46
phosphate
45
MTT
42
glucose
40
MEK
39
methionine
39
PEG
39
calcium
35
cysteine
33
ATP
32
PEG
32
serine
30
Gly
30
iron
27
lysine
26
TNM
26
leucine
25
ethanol
24
copper
24
acetate
24
ACS
23
ACS
22
sodium
21
ASA
19
hydrogen
18
PGE2
17
His
17
aspartic acid
17
aspartic acid
17
aspartic acid
17
aspartic acid
17
threonine
16
iodine
15
alanine
15
CAM
14
SCC
13
nitrogen
13
5-FU
13
cAMP
12
urea
12
bromide
12
zinc
11
SDS
11
H2O2
11
galactose
11
Sphingosine
11
PMA
10
AMP
10
Neo
10
pyrimidine
10
pyrimidine
10
Phe
9
Heparin
9
DTPA
9
cobalt
9
selenium
9
NH2
9
APN
9
Adriamycin
9
MAP
8
Curcumin
8
dUTP
8
cGMP
7
Rapamycin
7
proline
7
quinoline
7
COS
7
anthracene
7
DDP
7
more...