Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1519176 (PSA)
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Human Gene/Protein
zinc finger protein 132 12.5
MANSC1 12.5
FAM13C 12.5
LDLRAD1 12.5
MYL9 protein 12.5
kallikrein-related peptidase 15 12.5
PSA 12.5
DKFZP564K247 12.5
KLK15 protein 11.5
56 AA 11.5
PRSSL1 11.5
TARP protein 11.5
NRPN 11.5
cell division cycle associated 3 11.5
HSD3B2 protein 11.5
hK3 11.0
C10orf88 10.9
B9 protein 10.9
ribosome binding protein 1 10.9
KLK-L3 10.9
kallikrein 9 10.9
KLK3 10.7
Pleomorphic adenoma gene 1 10.6
MGAT4C 10.5
KLK2 10.3
BAF53A 10.2
PCDHB9 10.2
breast carcinoma amplified sequence 1 10.2
TMED3 10.2
HSPC111 10.2
PROSTATE 10.2
SLC16A6 10.2
p27 kip1 9.9
ERGIC1 9.9
D-PCa-2 9.9
p53-regulated apoptosis-inducing protein 1 9.9
FGF-BP3 9.9
PSA2 9.8
TGM4 9.8
KLK15 9.7
KLKP1 9.7
cystatin-like molecule 9.7
CCNG2 protein 9.7
CYB5R2 9.7
TMTC3 9.7
DRE 9.6
PSMA 9.6
PSAP 9.5
HSPBAP1 9.5
prostein 9.5
nuclear receptor interaction protein 9.5
HSD17B6 9.5
PtdIns(3,4,5)P3-binding protein 9.5
KLK4 9.5
gamma-seminoprotein 9.5
ST8SIA2 9.4
FLNA protein 9.3
57kD 9.3
PHC3 9.3
NKX3.1 9.3
TBL1Y 9.3
AP-2 like 9.3
neural cell adhesion molecule 9.3
puromycin-sensitive aminopeptidase 9.2
hK2 9.2
New gene expressed in prostate 9.2
PF4V1 9.2
MAGEA2 9.2
homeobox C6 9.2
neural adhesion molecule 9.2
aldehyde dehydrogenase 1A3 9.2
kallikrein-like serine protease 9.1
PSGR 9.1
ST8Sia IV 9.1
INCA1 9.0
SPINLW1 9.0
EIF3S3 9.0
glutathione peroxidase 6 9.0
AOF1 9.0
Tbr-1 9.0
more...
Disease
PSA 12.5
AREI 11.5
Prostatic atrophy 11.5
prostate nodule 11.1
stage C prostate cancer 10.0
LEL 9.7
hormone refractory prostate cancer 9.4
androgen independent prostate cancer 9.4
PIN III 9.2
recurrent prostate cancer 9.1
Acute prostatitis 9.0
High grade prostatic intraepithelial neoplasia 9.0
prostate cancer stage 8.8
Occupational Cancer 8.8
HPCX 8.7
Autosomal recessive hypophosphatemic rickets 8.7
stage B prostate cancer 8.5
stage A prostate cancer 8.5
STL 8.5
prostatic disease 8.4
Scrotum 8.4
Genitourinary Cancers 8.4
prostatic adenoma 8.4
Prostate Cancer 8.4
prostatic adenocarcinoma 8.3
Scrotum 8.2
prostate cancer 8.1
Adult growth hormone deficiency 8.0
Endobronchial metastases 7.9
Adenocarcinoma of the rete testis 7.9
PCAP 7.9
bilateral cancer 7.8
stage D prostate cancer 7.8
dysbasia 7.6
Nephrogenic adenoma 7.5
Urethra 7.5
Urethra 7.5
Prostate tumor 7.5
LCA 7.5
Urethra 7.5
PIN 7.4
HPC1 7.4
Bladder neck 7.4
urinary system cancer 7.3
prostatitis 7.2
coronary artery rupture 7.1
locally advanced cancer 7.1
articulation disorder 7.0
high-risk cancer 7.0
PIN 7.0
Hurthle cell adenoma 6.9
SMA II 6.8
HBD 6.8
Teratocarcinoma 6.7
measurable disease 6.7
adenocarcinoma of unknown primary 6.7
residual cancer 6.6
benign hypertension 6.6
seminal vesicles 6.6
Oligodendroglioma 6.5
bone metastases 6.5
Scott syndrome 6.4
Prostatitis 6.4
Extramammary Paget's disease 6.3
carcinoma of unknown origin 6.3
ASAP 6.3
unknown primary cancer 6.3
spermatocele 6.2
prostatic obstruction 6.2
GS3 6.1
refractory cancer 6.0
recurrent bladder cancer 5.9
Semantic dementia 5.9
Androgen deficiency 5.9
Primary leiomyosarcoma 5.8
Large cell neuroendocrine carcinoma 5.8
MDK 5.8
ODA 5.7
RHS 5.7
pediatric solid tumor 5.6
more...
Symptom
prostate problem 11.5
swollen prostate 10.9
Injection site pain 8.2
prostatism 7.8
GI irritation 6.5
Lower urinary tract symptoms 6.5
Acute urinary retention 6.5
Urge incontinence 6.5
Sister Mary Joseph's nodule 6.3
dysuria 5.7
bone pain 5.5
frequent urination 5.1
fasciculation 5.0
HSA 4.1
Physical findings 4.1
hot flashes 4.0
urinary frequency 4.0
muscle cramps 3.7
tenesmus 3.6
POA 3.4
nipple discharge 3.4
decreased appetite 3.3
Fluctuation 3.3
hot flushes 3.2
leg edema 3.1
partial seizure 3.1
blurred vision 3.1
groin pain 2.9
renal colic 2.8
acute stress 2.7
pelvic pain 2.5
joint stiffness 2.5
eds 2.4
Postoperative pain 2.4
bitter taste 2.0
chills 2.0
hoarseness 2.0
despair 1.8
back pain 1.7
functional recovery 1.6
anorexia 1.6
fatigue 1.5
discomfort 1.5
twitching 1.5
apathy 1.5
skin irritation 1.4
discomfort 1.4
pain 1.2
nausea 1.2
shortness of breath 1.2
tremor 1.1
ENT 1.1
cachexia 1.0
lethargy 1.0
agitation 0.9
dizziness 0.8
ophthalmoplegia 0.8
exertional dyspnea 0.8
insomnia 0.7
arthralgia 0.7
overweight 0.6
dysarthria 0.6
diarrhea 0.4
analgesia 0.3
anesthesia 0.3
low back pain 0.2
constipation 0.2
numbness 0.2
hyperoxia 0.2
dyspnea 0.1
hepatomegaly 0.0
weakness -0.1
vomiting -0.1
myalgia -0.2
collapse -0.3
seizures -0.3
dystonia -0.5
hypothermia -0.6
nausea and vomiting -0.7
splenomegaly -0.8
more...
Drug
Ibutamoren mesylate 11.5
Talactoferrin alfa 11.5
Canfosfamide hydrochloride 10.5
Lasofoxifene tartrate 10.5
Telavancin hydrochloride 10.2
Lumiliximab 9.9
ProstaScint 9.8
Apaziquone 9.7
Succinobucol 9.5
Focalin 9.3
Indiplon 9.3
4-Hydroxycoumarin 8.8
Emcyt 8.8
Indisulam 8.7
Maribavir 8.6
Bazedoxifene acetate 8.6
Dutasteride 8.5
Eulexin 8.3
SR 57746A 8.3
Almora 8.3
Metreleptin 8.1
PT-141 8.0
Peginterferon alfa-2b 8.0
Peginterferon alfa-2b 8.0
Aliskiren fumarate 7.9
Micafungin sodium 7.9
R1881 7.8
Satraplatin 7.7
Fampridine 7.7
Casodex 7.7
Provenge 7.7
Tulobuterol 7.6
Duloxetine hydrochloride 7.6
Estracyt 7.5
Retapamulin 7.5
Florisil 7.4
Escitalopram oxalate 7.4
Teduglutide 7.4
Pemetrexed disodium 7.4
Andriol 7.3
Lonafarnib 7.3
Methyl aminolevulinate 7.3
GNA 7.2
Doxifluridine 7.2
Estracyt 7.2
Azilect 7.2
CDX 7.1
Valdecoxib 7.0
Pegasys 7.0
Frovatriptan 6.7
Darbepoetin alfa 6.7
Genasense 6.7
CDX 6.7
Certolizumab pegol 6.6
Hyoscyamine 6.5
Docetaxel 6.5
ACT 6.5
Finasteride 6.3
Pyridoxamine 6.3
Triptorelin 6.3
Alefacept 6.2
Hyoscyamine 6.2
Drotrecogin alfa 6.2
Drotrecogin alfa 6.2
Telbivudine 6.2
Ixabepilone 6.1
Sandostatin LAR 6.1
Epoetin 6.0
Ciclesonide 6.0
AMK 5.9
Belimumab 5.9
Perphenazine 5.8
Marcaine 5.8
DHT 5.8
DHT 5.7
TPV 5.6
Pimecrolimus 5.6
Adefovir dipivoxil 5.6
Nesiritide 5.5
Zoladex 5.5
more...
Enzyme
snapalysin 12.5
kallikrein 9 10.9
kallikrein 13 10.2
endo-N 9.1
prostate-specific membrane antigen 8.6
prostate-specific antigen 8.1
neurosin 7.5
alpha-methylacyl-CoA racemase 7.3
neuropsin 7.2
phosphoserine aminotransferase 7.1
KLK7 7.0
hepsin 6.9
hepsin 6.9
neuropsin 6.9
KLK13 6.7
phosphatidylserine synthase 6.5
leishmanolysin 6.3
PST 6.3
5alpha-reductase 6.2
5alpha-reductase 6.2
tissue kallikrein 6.2
HDR 6.1
alanine aminopeptidase 6.0
phosphatidylserine decarboxylase 5.9
kallikrein 5.9
alpha-lytic protease 5.7
callose synthase 5.7
phosphoserine phosphatase 5.4
N-acetylglucosaminyltransferase 5.1
aspartoacylase 4.9
aminopeptidase B 4.7
PPH 4.6
iodothyronine 5'-deiodinase 4.4
murein hydrolase 4.2
histone demethylase 4.2
acrosin 4.1
caspase-11 4.1
caspase-11 4.0
trypanothione reductase 4.0
guanylate kinase 4.0
matriptase 4.0
sialyltransferase 3.9
sialyltransferase 3.9
sialyltransferase 3.9
PMT 3.9
TSA 3.9
cellulose synthase 3.8
glutamate decarboxylase 3.7
MDP 3.7
matriptase 3.5
thymidine phosphorylase 3.5
CYP27A1 3.4
aromatic L-amino acid decarboxylase 3.4
HK2 3.4
meprin 3.4
acid phosphatase 3.4
estrogen sulfotransferase 3.4
MTD 3.3
15-hydroxyprostaglandin dehydrogenase 3.2
acetolactate synthase 3.2
STR 3.2
LPL 3.1
type III procollagen 3.1
alpha-glucosidase 3.0
DAT 3.0
CEP 3.0
PNGase F 2.9
prolyl endopeptidase 2.9
dihydropyrimidine dehydrogenase 2.8
GABA transaminase 2.8
GSK 2.8
TSP-1 2.8
ALDH 2.7
sialidase 2.7
p100 2.7
glucose oxidase 2.7
histone acetyltransferase 2.7
enolase 2.6
3beta-hydroxysteroid dehydrogenase 2.6
C3 convertase 2.6
more...
Compound
Acid orange 63 12.5
DG 2 10.7
3-ethoxy-1,2-propanediol 10.7
4-sulfophthalic acid 10.2
3-pyridinesulfonic acid 10.2
4-sulfophthalic acid 10.2
methaneseleninic acid 9.9
Pyrazine diazohydroxide 9.7
methaneseleninic acid 9.7
Pindone 9.7
octyl acrylate 9.7
2-(trifluoromethyl)benzonitrile 9.5
3-pyridinesulfonic acid 9.5
Cinchophen 9.5
Di(2-ethylhexyl) adipate 9.3
2-(trifluoromethyl)-1H-benzimidazole 9.3
2-(trifluoromethyl)-1H-benzimidazole 9.3
NHS-Biotin 9.2
AFU 9.0
Pyrazine diazohydroxide 9.0
Avermectin B1a 8.3
Hexazinone 8.2
sebacic acid 8.1
sebacic acid 8.1
Kresoxim-methyl 8.1
Bicalutamide 8.1
3,5-dimethylisoxazole 8.0
sebacic acid 8.0
Estramustine 7.9
1-benzylpiperazine 7.6
PAP 7.6
Diisononyl phthalate 7.6
Aminoantipyrine 7.5
Tectorigenin 7.5
Quazepam 7.4
PAP 7.4
PAP 7.4
PAP 7.3
2-methylpropanamide 7.3
Estracyt 7.1
Estracyt 7.1
Blue Tetrazolium 7.1
Methylazoxymethanol 7.1
Nitroxoline 7.1
Dorzolamide 7.0
PNA 7.0
Androgen 7.0
Lubiprostone 7.0
Ethylketocyclazocine 6.9
Docetaxel 6.8
Hinokitiol 6.6
PIN 6.6
Ricinoleic acid 6.5
Dicofol 6.5
dipentyl 6.5
2-ethylhexyl acrylate 6.5
Perillyl alcohol 6.5
Methyllycaconitine 6.5
Perillyl alcohol 6.5
C6H10 6.5
Zinc pyrithione 6.4
Zinc pyrithione 6.4
Zinc pyrithione 6.4
PAPP 6.4
W37 6.4
mCPBG 6.4
Pyridoxamine 6.3
PNB 6.3
Emtricitabine 6.2
PAPP 6.2
Kallikrein 6.1
hydroxy coumarin 6.1
Calcein AM 6.1
Bromophenol Blue 6.1
KDN 6.1
DPC 6.0
DPC 6.0
Noscapine 6.0
Terazosin 6.0
Emetine 5.9
more...