Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1389183 (autodigestion)
 317 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
KREMEN2 13.8
protease serine 1 13.4
GORASP2 13.0
muCANP 12.4
PRSS1 12.0
gep 12.0
cationic trypsinogen 12.0
CTRC 11.8
Maid 11.8
Golgi reassembly stacking protein 11.7
PRSS2 11.7
ABIN-2 11.5
mCANP 11.3
Shwachman-Bodian-Diamond syndrome 11.3
pancreatic secretory trypsin inhibitor 11.1
trypsinogen 11.0
INGAP 10.7
UVS 10.6
enteropeptidase 10.5
calcium-activated neutral protease 10.4
GRASP55 10.4
Calpain-1 10.4
PSTI 10.2
C1 esterase 10.2
anionic trypsinogen 10.1
CPA1 9.7
Hageman factor 9.4
kininase I 9.3
TIM23 9.2
bikunin 8.6
IFIH1 8.4
gastric mucin 8.4
FXI 8.3
ATG16L1 8.3
intestinal mucin 8.3
Cathepsin B 8.2
SSAT 8.2
ML-1 8.2
C1-INH 8.1
pancreatic phospholipase A2 8.0
CGT 8.0
alternative protein 7.9
TGT 7.9
FACE 7.9
NOXA 7.9
CASP 7.8
AMBP 7.8
colipase 7.8
cathepsin B 7.8
PDX-1 7.8
Trypsin 7.8
dectin-1 7.7
Plasmin 7.7
p20 7.7
cysteine proteinase 7.5
histocompatibility antigen 7.4
ADH2 7.4
enterokinase 7.4
metalloendopeptidase 7.4
Mucin 7.3
Kallikrein 7.3
Chymotrypsin 7.2
lactase 7.2
PGM 7.0
MAL 7.0
CD94 7.0
carboxypeptidase B 6.9
CAC 6.9
28 kDa 6.9
xanthine dehydrogenase 6.9
protein B 6.9
endoprotease 6.9
C1 inhibitor 6.8
adenyl cyclase 6.8
Phospholipase A2 6.7
factor XI 6.7
alpha2-macroglobulin 6.6
serine protease 6.6
trypsin inhibitor 6.6
calpain inhibitor 6.6
chymotrypsin 6.5
AGA 6.5
TSK 6.4
PPP 6.4
PHB 6.4
calpastatin 6.4
PAF receptor 6.4
MUC2 6.3
serine protease inhibitor 6.3
cathepsin 6.3
repressor protein 6.3
antichymotrypsin 6.3
neurofilament protein 6.3
lipase 6.3
protease inhibitor 6.2
progranulin 6.2
amylase 6.2
MUC5AC 6.2
vWF 6.2
CFTR 6.2
interleukin 10 6.1
calpain 6.1
tissue transglutaminase 6.1
MOLT 6.0
metalloprotease 6.0
C/EBP homologous protein 5.9
TAP 5.9
phospholipase A2 5.9
Bax protein 5.9
kallikrein 5.9
endonuclease 5.9
alpha-amylase 5.9
chymotrypsin-like 5.9
TRP 5.9
Hsp60 5.8
pepsinogen 5.8
Protein A 5.8
Plasminogen 5.7
AP2 5.7
serum amyloid A 5.6
DIC 5.6
AP1 5.6
PCI 5.6
cysteine protease 5.5
DNase 5.5
Bid 5.4
PIP 5.4
Vimentin 5.3
Bak 5.3
ACR 5.2
PAP 5.2
cholecystokinin 5.2
PAF 5.2
H2B 5.2
matrix metalloproteinase 2 5.1
galectin-3 5.1
esterase 5.1
alpha 1-antitrypsin 5.1
glucose-6-phosphatase 5.0
mucin 5.0
H2A 5.0
CD31 4.9
plasminogen 4.9
collagenase 4.9
BCL2 4.8
casein 4.8
desmin 4.8
acetyltransferase 4.8
aminopeptidase 4.8
bcl-2 4.7
THC 4.7
RPMI 4.6
acid phosphatase 4.6
RNA polymerase I 4.6
dynorphin 4.6
xanthine oxidase 4.5
helicase 4.5
aldehyde dehydrogenase 4.5
crystallin 4.5
somatostatin 4.5
SDS 4.5
CD11c 4.5
adenosine receptor 4.5
COX-1 4.5
cathepsin D 4.4
cytokeratin 4.4
CAS 4.4
tropomyosin 4.4
urokinase-type plasminogen activator 4.3
haptoglobin 4.3
secretin 4.3
interleukin-10 4.3
endoplasmic reticulum 4.2
ALL 4.2
glucan 4.2
transcriptional repressor 4.2
Walker 4.1
cadherin 4.1
S100 4.1
myosin heavy chain 4.0
interleukin 2 4.0
ASA 4.0
serum protein 3.9
Dictyostelium 3.9
alcohol dehydrogenase 3.9
PTH 3.9
TOF 3.9
brush border 3.9
ribonucleoprotein 3.9
thyroglobulin 3.8
peroxisome proliferator-activated receptor gamma 3.8
Boc 3.8
myelin basic protein 3.8
CRP 3.7
bradykinin 3.7
cytochrome c 3.7
polypeptide 3.6
DNase I 3.6
G protein-coupled receptor 3.6
VIII 3.6
proximal tubule 3.6
elastin 3.5
glucagon 3.5
peroxisome proliferator-activated receptor 3.5
myoglobin 3.5
vimentin 3.4
GST 3.4
insulin receptor 3.4
angiotensin II 3.4
membrane-bound 3.4
von Willebrand factor 3.3
keratin 3.3
ICP 3.3
THP 3.3
RNA polymerase II 3.3
LDH 3.3
mitogen-activated protein 3.2
NHS 3.2
MHC 3.2
LHRH 3.2
epididymal 3.2
AP-1 3.2
heavy chain 3.2
cyclooxygenase-2 3.1
interleukin-6 3.1
dimeric 3.1
COX-2 3.0
glutathione S-transferase 2.9
gut 2.8
histone 2.7
fibrinogen 2.7
TNF 2.7
hemoglobin 2.7
matrix metalloproteinase 2.7
fibronectin 2.6
cytokine 2.6
TLR4 2.6
dilute 2.6
glial fibrillary acidic protein 2.6
PLA 2.6
calcitonin 2.6
Met 2.5
cyclooxygenase 2.5
phosphodiesterase 2.5
IL-1 2.4
ROS 2.4
lymphoid 2.3
ACTH 2.3
SOD 2.3
peroxidase 2.3
substance P 2.2
serum albumin 2.1
insulin 2.1
alkaline phosphatase 2.1
C-reactive protein 2.0
calmodulin 2.0
threonine 2.0
Pseudomonas 2.0
She 1.9
phosphatase 1.8
tumor necrosis factor 1.8
membrane protein 1.8
hole 1.8
microsomal 1.7
IgA 1.6
ATP 1.6
Bcl-2 1.6
thrombin 1.6
renin 1.5
Mol 1.4
thymus 1.3
MRI 1.2
catalase 1.1
CO2 1.0
fused 0.8
IL-6 0.8
albumin 0.7
glycoprotein 0.7
collagen -0.3
Sep -0.3
Gen -0.4
Disease
Obstructive chronic pancreatitis 15.0
Hereditary chronic pancreatitis 13.4
Edematous pancreatitis 11.8
Acute necrotizing pancreatitis 11.7
UVS 10.9
Pancreatic pseudocyst 10.7
pancreatic abscess 9.9
HPC 9.3
acute pancreatitis 9.3
biliary tract disease 9.1
alcoholic pancreatitis 8.7
pancreatitis 8.7
Intestinal ischemia 8.3
pancreatic fibrosis 8.2
Arthus reaction 7.9
chronic pancreatitis 7.9
platelet disorder 7.9
pancreatic insufficiency 7.6
protein deficiency 7.6
prurigo 7.4
Farber 7.3
lactose intolerance 7.1
parakeratosis 6.9
carcinoma of the pancreas 6.5
PPP 6.4
Hereditary angioedema 6.2
nephrocalcinosis 6.1
Pancreas 6.1
panniculitis 5.9
hyperlipoproteinemia 5.9
EDC 5.9
Pancreas 5.8
AGA 5.8
cardiac tamponade 5.8
acute disease 5.6
hypercortisolism 5.6
gallstones 5.5
THC 5.5
alcohol abuse 5.5
teratoma 5.4
malabsorption 5.4
secondary infection 5.3
childhood ALL 5.3
pericardial effusion 5.3
alcoholism 5.3
PAF 5.1
invasive cancer 5.0
hyperkeratosis 5.0
polyarthritis 4.9
bronchogenic carcinoma 4.8
intussusception 4.7
SDS 4.7
myeloid leukemia 4.7
FAS 4.6
peptic ulcer 4.6
cellulitis 4.6
disseminated intravascular coagulation 4.5
ileus 4.5
hyperparathyroidism 4.5
genetic disorder 4.5
lymphedema 4.4
pancreatic cancer 4.3
hypercalcemia 4.3
gastric ulcer 4.3
muscular dystrophy 4.1
Duchenne muscular dystrophy 3.7
peritonitis 3.7
hyperlipidemia 3.7
metabolic syndrome 3.6
sepsis 3.5
Blocking 3.5
suicide 3.4
pulmonary tuberculosis 3.4
sepsis 3.3
ICP 3.3
ischemia 3.3
acute lymphoblastic leukemia 3.2
NHS 3.2
myopathy 3.1
aggressiveness 3.0
cystic fibrosis 3.0
rare disease 3.0
Poland 2.9
celiac disease 2.9
malnutrition 2.8
pruritus 2.8
myelodysplastic syndrome 2.8
Leukemia 2.7
acute myeloid leukemia 2.5
Best 2.5
confusion 2.2
leukemia 2.1
hepatocellular carcinoma 2.1
cytomegalovirus 1.8
cataract 1.8
aggression 1.8
hyperglycemia 1.8
cold 1.7
hepatitis C 1.6
diabetes 1.5
virus infection 1.0
carcinoma 1.0
anemia 0.9
hypertension 0.8
tumorigenesis 0.8
tumor growth 0.8
prostate cancer 0.8
carcinogenesis 0.6
myocardial infarction 0.6
adenocarcinoma 0.6
tumor 0.6
arthritis 0.5
melanoma 0.5
heart failure 0.5
tuberculosis 0.4
atherosclerosis 0.4
metastases -0.0
cancer -0.3
obesity -0.3
depression -0.8
Symptom
autodigestion 16.6
epigastric pain 5.9
abdominal pain 4.7
chest pain 4.1
paresis 4.1
starvation 4.0
distraction 3.4
acidity 2.7
hypothermia 2.5
collapse 1.8
pain 0.2
Drug
Glumal 16.6
Gabexate mesilate 10.4
Asparaginase 8.6
Sucralfate 8.5
Lactase 8.5
Ginger 7.7
Lactose 7.5
Tuberculin 7.4
DFP 6.8
FeCl3 6.2
balanced salt solution 6.0
Vitamin E 4.9
lactose 4.2
Asn 4.1
CaCl2 4.0
CaCl2 4.0
CaCl2 3.9
PTH 3.9
NH3 3.8
DNase I 3.6
lysine 3.6
nitroglycerin 3.5
Ethanol 3.4
caffeine 3.2
Gel 2.8
ROS 2.4
Leaf 2.2
ascorbate 2.1
Monit 1.5
Dermatol -0.4
Cardiovasc -1.0
Enzyme
UmuD protein 12.7
bacillolysin 12.3
LexA repressor 11.9
C1 esterase 10.6
stem bromelain 9.9
alpha-lytic protease 9.8
PHB depolymerase 9.8
oligopeptidase B 9.6
hatching enzyme 9.6
tripeptidase 9.6
Hageman factor 9.2
astacin 8.7
clostripain 8.7
enterokinase 8.2
ficin 8.2
dextranase 8.0
CPN 7.8
CGT 7.8
cathepsin B 7.8
3C protease 7.7
TGT 7.6
carboxypeptidase B 7.4
acrosin 7.2
mu-calpain 7.2
lactase 7.1
isoamylase 7.1
CEP 7.1
trypsin 7.1
cathepsin G 6.8
micrococcal nuclease 6.7
bromelain 6.6
chymotrypsin 6.4
xanthine dehydrogenase 6.3
carboxypeptidase Y 6.3
PGM 6.2
lipase 6.1
endonuclease 5.9
deaminase 5.9
pepsin 5.9
alpha-amylase 5.8
plasmin 5.8
thermolysin 5.7
DNase 5.7
kallikrein 5.6
phospholipase A2 5.6
papain 5.5
subtilisin 5.5
matrix metalloproteinase 2 5.4
sucrase 5.4
MDP 5.2
asparaginase 5.2
beta-glucosidase 5.1
glucose-6-phosphatase 5.0
beta-glucosidase 4.9
hexosaminidase 4.8
S1 nuclease 4.8
collagenase 4.8
cathepsin D 4.6
xanthine oxidase 4.6
xylanase 4.6
acid phosphatase 4.6
aldehyde dehydrogenase 4.5
aldehyde dehydrogenase 4.5
xylanase 4.5
aldehyde dehydrogenase 4.5
elastase 4.5
transglutaminase 4.4
invertase 4.3
aldehyde dehydrogenase 4.3
urokinase-type plasminogen activator 4.2
aldehyde dehydrogenase 3.9
ribonuclease 3.9
ribonuclease 3.9
proteasome 3.8
beta-galactosidase 3.8
cytochrome oxidase 3.5
topoisomerase 3.5
alcohol dehydrogenase 3.4
topoisomerase 3.3
RNase 2.6
DNA polymerase 2.6
RNA polymerase 2.5
RNase 2.5
phosphodiesterase 2.4
creatine kinase 2.4
adenylate cyclase 2.4
glutathione S-transferase 2.2
alkaline phosphatase 2.1
protein kinase C 2.0
peroxidase 1.6
thrombin 1.6
renin 1.5
catalase 0.9
protein kinase 0.3
Compound
Aceglutamide 14.3
Calotropin 13.4
Calotropin 13.3
Calotropin 13.2
DPPD 10.6
Azocoll 10.5
Saccharin 8.6
Sucralfate 8.5
Chloral hydrate 8.5
Glu-Glu 8.5
6-aminohexanoic acid 8.5
6-aminohexanoic acid 8.5
PMSF 8.5
Taurocholate 8.4
TPCK 8.1
NOXA 8.1
Plasmin 8.0
TGT 7.9
Trypsin 7.8
Tetrahydrocannabinol 7.5
3-hydroxybutyric acid 7.5
Lactose 7.4
Kallikrein 7.2
Docosahexaenoic acid 6.9
MAL 6.8
Glutaraldehyde 6.7
NEM 6.7
Octreotide 6.7
Artemisinin 6.7
Pro-Gly 6.2
CCP 5.9
TAP 5.9
MIT 5.8
MIT 5.8
EDC 5.8
DTT 5.6
PHB 5.6
DTT 5.6
Bradykinin 5.5
MIA 5.4
Leucine 5.4
methyl methanesulfonate 5.4
L-leucine 5.4
HEPES 5.4
Vimentin 5.3
DIC 5.3
PAP 5.2
octyl 5.1
octyl 5.1
octyl 5.1
DEAE 5.1
PAP 5.0
PAP 5.0
Cysteine 4.9
PAP 4.9
Serine 4.9
EDTA 4.7
EDTA 4.7
2-mercaptoethanol 4.6
Vitamin E 4.6
Gly 4.6
Sodium 4.4
isopropanol 4.4
thiourea 4.4
SDS 4.4
hydroxylamine 4.2
hydroxylamine 4.2
Dexamethasone 4.0
CaCl2 3.9
Melatonin 3.9
TOF 3.9
HCl 3.9
cysteine 3.9
vanadium 3.9
Ile 3.9
acetone 3.8
acridine 3.8
acetaldehyde 3.8
Triton X-100 3.7
alanine 3.7
serine 3.6
alcohol dehydrogenase 3.6
acrylamide 3.6
TCA 3.5
Tris 3.5
lysine 3.5
guanidine 3.5
chloroform 3.4
Mg2+ 3.4
arginine 3.4
leucine 3.3
isoleucine 3.3
Phe 3.3
Tris 3.3
THP 3.3
aspartic acid 3.3
isoleucine 3.3
aspartic acid 3.3
THP 3.2
caffeine 3.2
aspartic acid 3.1
Asp 3.1
methionine 3.1
ammonium 3.0
aspartic acid 3.0
phenol 2.9
methane 2.9
Insulin 2.8
PGE2 2.8
threonine 2.8
valine 2.8
carbonate 2.8
zinc 2.8
calcium 2.7
H2O2 2.7
TNF 2.7
ASA 2.7
NH2 2.7
His 2.7
ethanol 2.7
formaldehyde 2.7
sulfate 2.6
urea 2.6
nicotinamide 2.6
cyanide 2.6
Optimal 2.5
aldehyde 2.4
ACTH 2.4
formaldehyde 2.3
tryptophan 2.3
salt 2.1
DNA 2.1
tyrosine 2.0
aldehyde 2.0
hydroxide 2.0
sodium 2.0
mercury 1.9
cobalt 1.8
cAMP 1.8
hydrogen 1.8
silver 1.7
nitrogen 1.7
proline 1.6
ATP 1.6
manganese 1.5
cadmium 1.5
tryptophan 1.5
tryptophan 1.5
tryptophan 1.5
galactose 1.4
glucose 1.4
glycerol 1.3
oxygen 1.3
bromide 1.2
ammonia 1.2
phosphorus 1.1
copper 1.1
phosphate 0.8
methanol 0.7
iron 0.5
ACS 0.4
CO2 0.2
nitric oxide 0.0
water 0.0
Dec -0.0
acetate -0.2
Clin -0.5
Cardiol -1.2