Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1389183 (
autodigestion
)
317
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The specific susceptibility of the intestinal mucosa to low blood flow states is related to the "physiologic" makeup of the intestinal milieu. Pancreatic proteases appear to play a crucial role in the ischemic
autodigestion
of the intestinal mucosa. Moreover, trypsin can activate the conversion of
xanthine dehydrogenase
into superoxide radicals producing xanthine oxidase. Oxygen-derived free radicals account for at least part of the damage to the postischemic intestinal mucosa.
...
PMID:Pancreatic proteases and oxygen-derived free radicals in acute ischemic enteropathy. 351 Apr 80
