Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C1335475 (Primary Carcinoma)
 3 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper presents the clinical and histopathological features of 221 Primary Carcinoma Liver studied over the last eight years. HBsAg studies were carried out in 93, AFP studies in 87 and both HBsAg and AFP in the same serum samples in 78. HBsAg positivity rate by CIEP was 29% and AFP positivity was 52%. There appears to be greater AFP posivity in HBsAg positive group compared to HBsAg negative group. Correlation of cell type with AFP positivity reveals significant greater positivity in clear type. The need for indepth studies to use morphological appearances of cancer cells as simple marker of altered function is suggested. Anti e was positive in 40% of HBsAg positive cases studied for e system, while e antigen was positive in 32%. A very unusual finding of e antigen and Anti e present at the same time in a patient with primary liver carcinoma is documented.
 ...
PMID:Correlated clinical, histopathological, HBV and AFP studies of primary carcinoma liver. 615 6

A number of major modifications were made to the classification of head and neck carcinomas in the eighth edition of the American Joint Committee on Cancer, Cancer Staging Manual and Union for International Cancer Control TNM classification of Malignant Tumors. These modifications were aimed at improving the prognosis prediction accuracy of the system. In this article, we review the new edition of the TNM classification system. Among the several changes in the new system, a separate algorithm for p16-positive oropharyngeal carcinoma was included, as were new chapters on 'Head and Neck Skin Carcinoma' and 'Unknown Primary Carcinoma-Cervical Nodes.' Changes to Tumor (T) classification were made by introducing the depth of invasion of oral carcinoma, whereas changes to Node (N) classification were made by adding extra-nodal extension. It is believed that these changes will help improve the accuracy of the system in the prediction of prognosis. However, it is necessary to verify their validity through further clinical research.
 ...
PMID:A review of head and neck cancer staging system in the TNM classification of malignant tumors (eighth edition). 3119 32