UMLS:C1326912 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: UMLS:C1326912 (tumorigenesis)
57,481 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
Mol	5231
p53	4795
Sep	3474
catenin	1486
AKT	1388
histone	1167
PI3K	1124
mTOR	1078
cyclin D1	1063
p21	1054
cytokine	935
MAPK	855
ERK	838
E-cadherin	824
epidermal growth factor receptor	812
ubiquitin	760
c-Myc	747
tyrosine kinase	727
PTEN	717
Bcl-2	716
beta-catenin	701
STAT3	648
estrogen receptor	614
ras	612
vascular endothelial growth factor	603
cage	599
EGFR	587
proto-oncogene	583
p16	569
UTR	561
c-myc	556
caspase-3	555
lymphoid	545
insulin	526
p27	498
osteosarcoma	495
tumour suppressor	493
MYC	488
BRAF	482
KRAS	481
proteasome	479
APC	471
receptor tyrosine kinase	465
ERK1	459
TNM	451
IL-6	424
BRCA1	421
p38	415
HER2	408
gut	406
ATP	402
phosphatase	396
MEK	396
VEGF	393
cyclin	381
cyclooxygenase-2	374
CD44	370
JNK	350
matrix metalloproteinase	341
COX-2	336
Ki-67	335
epidermal growth factor	332
endoplasmic reticulum	331
c-Jun	325
TNF	323
proliferating cell nuclear antigen	321
histone deacetylase	321
histone H3	320
p65	314
tumor necrosis factor	308
threonine	307
K-ras	301
E3 ubiquitin ligase	300
collagen	298
adenomatous polyposis coli	297
androgen receptor	296
telomeric	293
EGF	289
cyclin E	284
vimentin	283

Disease
tumorigenesis	57481
cancer	29871
tumor	27041
carcinogenesis	4964
breast cancer	4758
tumor progression	4162
tumor growth	3757
carcinoma	3399
colorectal cancer	2708
hepatocellular carcinoma	2258
lung cancer	2188
adenocarcinoma	2012
prostate cancer	1600
squamous cell carcinoma	1443
colon cancer	1426
gastric cancer	1381
metastases	1379
melanoma	1179
glioma	1168
leukemia	1126
lymphoma	936
ovarian cancer	921
non-small cell lung cancer	879
pancreatic cancer	832
adenoma	774
glioblastoma	747
mammary tumor	736
tumor initiation	694
liver cancer	672
retinoblastoma	655
renal cell carcinoma	649
MCF	608
Epstein	576
cervical cancer	570
osteosarcoma	560
liver cancer	558
bladder cancer	545
aggressiveness	526
dysplasia	511
neuroblastoma	487
APC	480
neoplastic transformation	467
sarcoma	453
primary tumor	439
colitis	408
obesity	401
skin cancer	394
acute myeloid leukemia	377
brain tumor	371
Hepatocellular carcinoma	370
epithelial ovarian cancer	352
lung carcinoma	331
tumor angiogenesis	331
Hippel	326
diabetes	322
Kaposi's sarcoma	318
B-cell lymphoma	317
thyroid cancer	316
hepatitis B	314
glioblastoma multiforme	313
endometrial cancer	299
virus infection	297
WT1	296
ATM	289
multiple endocrine neoplasia	285
multiple myeloma	282
familial adenomatous polyposis	267
medulloblastoma	265
AS1	256
SCID	253
esophageal cancer	231
Hodgkin's disease	220
esophageal cancer	213
EMT	203
solid tumor	199
papilloma	196
skin tumor	196
oral cancer	196
inflammatory bowel disease	194
cirrhosis	190

Symptom
starvation	159
pain	64
cachexia	41
exhaustion	35
collapse	34
overweight	32
hepatomegaly	31
splenomegaly	27
diarrhea	26
seizures	24
ataxia	22
headache	17
fatigue	16
functional recovery	14
erythema	13
acidity	12
abdominal pain	10
weakness	10
anesthesia	9
thinning	9
vomiting	9
masculinization	8
anorexia	8
skin damage	7
hypotonia	7
cancer pain	7
chest pain	6
HSA	6
hepatosplenomegaly	6
hyperoxia	6
Scratch	6
skin irritation	5
constipation	5
nausea	5
respiratory distress	5
acute stress	5
insomnia	4
cerebellar ataxia	4
DNA marker	3
loss of balance	3
bone pain	3
menopausal symptoms	3
analgesia	3
dyspnea	3
ENT	3
pelvic pain	3
polydipsia	3
angina	2
nipple discharge	2
nipple discharge	2
cough	2
nausea and vomiting	2
anosmia	2
low back pain	2
colic	2
ACHE	2
hunger	2
spasticity	2
vertigo	2
flushing	2
myalgia	2
disturbed balance	2
memory loss	2
exertional dyspnea	1
neck pain	1
polyuria	1
agitation	1
chromosome marker	1
physical appearance	1
Decreased activity	1
syncope	1
chronic cough	1
acute abdominal pain	1
Cushingoid	1
dizziness	1
impaired motor coordination	1
skin irritant	1
sleepiness	1
tinnitus	1
intestinal bleeding	1

Enzyme
ERK	2910
mitogen-activated protein kinase	2221
luciferase	1299
protein kinase	1098
focal adhesion kinase	895
MEK	552
proteasome	483
APC	478
caspase-3	412
cdc2	302
protein kinase C	286
phosphatidylinositol 3-kinase	281
reverse transcriptase	272
PARP	234
glutathione S-transferase	220
phosphoinositide 3-kinase	213
GSK	199
DNA methyltransferase	197
AMP-activated protein kinase	194
RNA polymerase	192
ATPase	176
ornithine decarboxylase	175
calcineurin	155
IKK	152
AMPK	141
demethylase	135
catalase	131
AMPK	123
caspase-9	94
succinate dehydrogenase	94
superoxide dismutase	90
caspase-8	80
DNA polymerase	79
RNase	77
urokinase-type plasminogen activator	77
RNase	74
histone demethylase	69
endonuclease	68
MMP	68
PDK1	67
ACS	67
NQO1	65
caspase-1	63
alkaline phosphatase	62
glutathione peroxidase	61
peroxidase	60
topoisomerase	60
pyruvate kinase	60
aldehyde dehydrogenase	57
histone acetyltransferase	56
aldehyde dehydrogenase	55
isocitrate dehydrogenase	55
aldehyde dehydrogenase	54
aldehyde dehydrogenase	54
aldehyde dehydrogenase	54
topoisomerase	53
collagenase	53
gamma-glutamyl transpeptidase	52
complex I	51
protein phosphatase 2A	50
isocitrate dehydrogenase	49
MAP	48
lactate dehydrogenase	47
lipoxygenase	46
fumarase	45
transcriptase	45
trypsin	43
alanine aminotransferase	42
phospholipase A2	41
polo-like kinase 1	41
NADPH oxidase	40
beta-galactosidase	40
prostate-specific antigen	38
CD10	38
NADPH oxidase	38
MEKK1	36
thrombin	35
phosphodiesterase	35
phospholipase C	35
STK11	35