Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1326912 (
tumorigenesis
)
57,481
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
5231
p53
4795
Sep
3474
catenin
1486
AKT
1388
histone
1167
PI3K
1124
mTOR
1078
cyclin D1
1063
p21
1054
cytokine
935
MAPK
855
ERK
838
E-cadherin
824
epidermal growth factor receptor
812
ubiquitin
760
c-Myc
747
tyrosine kinase
727
PTEN
717
Bcl-2
716
beta-catenin
701
STAT3
648
estrogen receptor
614
ras
612
vascular endothelial growth factor
603
cage
599
EGFR
587
proto-oncogene
583
p16
569
UTR
561
c-myc
556
caspase-3
555
lymphoid
545
insulin
526
p27
498
osteosarcoma
495
tumour suppressor
493
MYC
488
BRAF
482
KRAS
481
more...
Disease
tumorigenesis
57481
cancer
29871
tumor
27041
carcinogenesis
4964
breast cancer
4758
tumor progression
4162
tumor growth
3757
carcinoma
3399
colorectal cancer
2708
hepatocellular carcinoma
2258
lung cancer
2188
adenocarcinoma
2012
prostate cancer
1600
squamous cell carcinoma
1443
colon cancer
1426
gastric cancer
1381
metastases
1379
melanoma
1179
glioma
1168
leukemia
1126
lymphoma
936
ovarian cancer
921
non-small cell lung cancer
879
pancreatic cancer
832
adenoma
774
glioblastoma
747
mammary tumor
736
tumor initiation
694
liver cancer
672
retinoblastoma
655
renal cell carcinoma
649
MCF
608
Epstein
576
cervical cancer
570
osteosarcoma
560
liver cancer
558
bladder cancer
545
aggressiveness
526
dysplasia
511
neuroblastoma
487
more...
Symptom
starvation
159
pain
64
cachexia
41
exhaustion
35
collapse
34
overweight
32
hepatomegaly
31
splenomegaly
27
diarrhea
26
seizures
24
ataxia
22
headache
17
fatigue
16
functional recovery
14
erythema
13
acidity
12
weakness
10
abdominal pain
10
anesthesia
9
vomiting
9
thinning
9
anorexia
8
masculinization
8
skin damage
7
cancer pain
7
hypotonia
7
HSA
6
chest pain
6
hyperoxia
6
Scratch
6
hepatosplenomegaly
6
respiratory distress
5
constipation
5
skin irritation
5
acute stress
5
nausea
5
cerebellar ataxia
4
insomnia
4
analgesia
3
polydipsia
3
more...
Drug
lysine
539
Dermatol
248
ROS
181
ETS
155
Monit
92
MAP
83
GEO
75
IL-2
61
IFN-gamma
57
vitamin E
48
Herceptin
47
Activin
47
PTC
45
ROC
45
Mutagen
44
CSF
40
caffeine
40
NADH
37
Estrogens
35
Imatinib
34
Cardiovasc
33
BLM
32
ascorbate
30
Paraffin
29
Retinoic acid
27
NVP
26
Sorafenib
26
uPA
25
G418
24
ICI
24
Gleevec
23
ABC
22
Gefitinib
22
Parkin
22
Parkin
22
Erlotinib
21
Gel
21
Bevacizumab
20
DNase I
20
Leaf
18
more...
Enzyme
ERK
2910
mitogen-activated protein kinase
2221
luciferase
1299
protein kinase
1098
focal adhesion kinase
895
MEK
552
proteasome
483
APC
478
caspase-3
412
cdc2
302
protein kinase C
286
phosphatidylinositol 3-kinase
281
reverse transcriptase
272
PARP
234
glutathione S-transferase
220
phosphoinositide 3-kinase
213
GSK
199
DNA methyltransferase
197
AMP-activated protein kinase
194
RNA polymerase
192
ATPase
176
ornithine decarboxylase
175
calcineurin
155
IKK
152
AMPK
141
demethylase
135
catalase
131
AMPK
123
caspase-9
94
succinate dehydrogenase
94
superoxide dismutase
90
caspase-8
80
DNA polymerase
79
RNase
77
urokinase-type plasminogen activator
77
RNase
74
histone demethylase
69
endonuclease
68
MMP
68
PDK1
67
more...
Compound
DNA
9217
Dec
3631
Clin
1831
oxygen
1218
tyrosine
1080
glucose
687
lysine
626
serine
605
anthracene
589
MTT
556
MDA
551
acetate
512
calcium
497
threonine
464
methionine
457
water
457
TNM
451
sodium
439
ATP
402
MEK
383
sulfate
370
TNF
323
cysteine
317
phosphate
315
DBA
313
arginine
290
pyrene
274
retinoic acid
246
zinc
225
cAMP
195
GTP
193
urea
185
leucine
184
iron
170
nitric oxide
164
hydrogen
162
NAD
155
glutamine
152
Histone
152
alanine
137
more...