Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C1323099 (
sympathomimetic
)
2,957
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Since the early 1960s, a number of pharmacologic agents have been used to treat children with enuresis. Success has been reported with tricyclic antidepressants (imipramine), anticholinergics (oxybutynin), and desmopressin acetate (
DDAVP
). Sedatives, stimulants, or
sympathomimetic
agents have not proved beneficial. Because treatment with medication may be effective even in children with an organic problem such as infection or neuropathy, patients should always be evaluated carefully before drug therapy is started. Of the tricyclic antidepressants, imipramine has been investigated and used the most extensively. Oxybutynin is beneficial for children with small bladder capacity and daytime enuresis.
DDAVP
, introduced in the 1990s, has response rates similar to those of imipramine but with fewer side effects.
...
PMID:Older pharmacologic therapy for nocturnal enuresis. 803 32
